Prophylactic mastectomy in BRCA1/2 mutation carriers and women at risk of hereditary breast cancer: long-term experiences at the Rotterdam Family Cancer Clinic von Heemskerk-Gerritsen, Bernadette A M, Brekelmans, Cecile T M, Menke-Pluymers, Marian B E, van Geel, Albert N, Tilanus-Linthorst, Madeleine M A, Bartels, Carina C M, Tan, Murly, Meijers-Heijboer, Hanne E J, Klijn, Jan G M, Seynaeve, Caroline

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Widespread domain-like perturbations of DNA methylation in whole blood of Down syndrome neonates von Henneman, Peter, Bouman, Arjan, Mul, Adri, Knegt, Lia, van der Kevie-Kersemaekers, Anne-Marie, Zwaveling-Soonawala, Nitash, Meijers-Heijboer, Hanne E J, van Trotsenburg, A S Paul, Mannens, Marcel M

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Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers von Heemskerk-Gerritsen, Bernadette A. M., Jager, Agnes, Koppert, Linetta B., Obdeijn, A. Inge-Marie, Collée, Margriet, Meijers-Heijboer, Hanne E. J., Jenner, Denise J., Oldenburg, Hester S. A., van Engelen, Klaartje, de Vries, Jakob, van Asperen, Christi J., Devilee, Peter, Blok, Marinus J., Kets, C. Marleen, Ausems, Margreet G. E. M., Seynaeve, Caroline, Rookus, Matti A., Hooning, Maartje J.

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Improved overall survival after contralateral risk‐reducing mastectomy in BRCA1/2 mutation carriers with a history of unilateral breast cancer: A prospective analysis von Heemskerk‐Gerritsen, Bernadette A.M., Rookus, Matti A., Aalfs, Cora M., Ausems, Margreet G.E.M., Collée, Johanna M., Jansen, Liesbeth, Kets, C. Marleen, Keymeulen, Kristien B.M.I., Koppert, Linetta B., Meijers‐Heijboer, Hanne E.J., Mooij, Thea M., Tollenaar, Rob A.E.M., Vasen, Hans F.A., HEBON, Hooning, Maartje J., Seynaeve, Caroline

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Combined germline pathogenic variants in FLCN and TP53 are associated with early onset renal cell carcinoma and brain tumors von Beek, Irma, Glykofridis, Iris E., Wagner, Anja, Toom, Dorine T., Bongers, Ernie M. H. F., Leenders, Geert J. L. H., Johannesma, Paul C., Meijers‐Heijboer, Hanne E. J., Wolthuis, Rob M. F., Steensel, Maurice A. M., Dubbink, Hendrikus J., Houweling, Arjan C.

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No evidence for increased prevalence of colorectal carcinoma in 399 Dutch patients with Birt-Hogg-Dubé syndrome von van de Beek, Irma, Glykofridis, Iris E., Wolthuis, Rob M. F., Gille, Hans J. J. P., Johannesma, Paul C., Meijers-Heijboer, Hanne E. J., Moorselaar, R. Jeroen A. van, Houweling, Arjan C.

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Renal imaging in 199 Dutch patients with Birt-Hogg-Dubé syndrome: Screening compliance and outcome von Johannesma, Paul C, van de Beek, Irma, van der Wel, Tijmen J W T, Reinhard, Rinze, Rozendaal, Lawrence, Starink, Theo M, van Waesberghe, Jan Hein T M, Horenblas, Simon, Gille, Hans J J P, Jonker, Marianne A, Meijers-Heijboer, Hanne E J, Postmus, Pieter E, Houweling, Arjan C, van Moorselaar, Jeroen R A

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Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations von Brohet, Richard M, Velthuizen, Maria E, Hogervorst, Frans B L, EJ Meijers-Heijboer, Hanne, Seynaeve, Caroline, Collée, Margriet J, Verhoef, Senno, Ausems, Margreet G E M, Hoogerbrugge, Nicoline, van Asperen, Christi J, Gómez García, Encarna, Menko, Fred, Oosterwijk, Jan C, Devilee, Peter, Veer, Laura J van't, van Leeuwen, Flora E, Easton, Douglas F, Rookus, Matti A, Antoniou, Antonis C

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Leptin receptor deficiency: a systematic literature review and prevalence estimation based on population genetics von Kleinendorst, Lotte, Abawi, Ozair, van der Kamp, Hetty J, Alders, Mariëlle, Meijers-Heijboer, Hanne E J, van Rossum, Elisabeth F C, van den Akker, Erica L T, van Haelst, Mieke M

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Clonality, Antigen Recognition, and Suppression of CD8 + T Cells Differentially Affect Prognosis of Breast Cancer Subtypes von Hammerl, Dora, Massink, Maarten P G, Smid, Marcel, van Deurzen, Carolien H M, Meijers-Heijboer, Hanne E J, Waisfisz, Quinten, Debets, Reno, Martens, John W M

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Increased prevalence of BRCA1/2 mutations in women with macrotextured breast implants and anaplastic large cell lymphoma of the breast von de Boer, Mintsje, Hauptmann, Michael, Hijmering, Nathalie J., van Noesel, Carel J.M., Rakhorst, Hinne A., Meijers-Heijboer, Hanne E.J., de Boer, Jan Paul, van der Hulst, René R.W.J., de Jong, Daphne, van Leeuwen, Flora E.

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PRDM10 directs FLCN expression in a novel disorder overlapping with Birt–Hogg–Dubé syndrome and familial lipomatosis von van de Beek, Irma, Glykofridis, Iris E, Oosterwijk, Jan C, van den Akker, Peter C, Diercks, Gilles F H, Bolling, Maria C, Waisfisz, Quinten, Mensenkamp, Arjen R, Balk, Jesper A, Zwart, Rob, Postma, Alex V, Meijers-Heijboer, Hanne E J, van Moorselaar, R Jeroen A, Wolthuis, Rob M F, Houweling, Arjan C

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Variation in mutation spectrum partly explains regional differences in the breast cancer risk of female BRCA mutation carriers in the Netherlands von Vos, Janet R, Teixeira, Natalia, van der Kolk, Dorina M, Mourits, Marian J E, Rookus, Matti A, van Leeuwen, Flora E, Collée, Margriet, van Asperen, Christi J, Mensenkamp, Arjen R, Ausems, Margreet G E M, van Os, Theo A M, Meijers-Heijboer, Hanne E J, Gómez-Garcia, Encarna B, Vasen, Hans F, Brohet, Richard M, van der Hout, Annemarie H, Jansen, Liesbeth, Oosterwijk, Jan C, de Bock, Geertruida H

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Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers von Kuchenbaecker, Karoline B, McGuffog, Lesley, Barrowdale, Daniel, Lee, Andrew, Soucy, Penny, Dennis, Joe, Domchek, Susan M, Robson, Mark, Spurdle, Amanda B, Ramus, Susan J, Mavaddat, Nasim, Terry, Mary Beth, Neuhausen, Susan L, Schmutzler, Rita Katharina, Simard, Jacques, Pharoah, Paul D P, Offit, Kenneth, Couch, Fergus J, Chenevix-Trench, Georgia, Easton, Douglas F, Antoniou, Antonis C

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Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium von Li, Hongyan, Terry, Mary Beth, Antoniou, Antonis C, Phillips, Kelly-Anne, Kast, Karin, Mooij, Thea M, Engel, Christoph, Noguès, Catherine, Stoppa-Lyonnet, Dominique, Lasset, Christine, Berthet, Pascaline, Mari, Veronique, Caron, Olivier, Barrowdale, Daniel, Frost, Debra, Brewer, Carole, Evans, D Gareth, Izatt, Louise, Side, Lucy, Walker, Lisa, Tischkowitz, Marc, Rogers, Mark T, Porteous, Mary E, Snape, Katie, Meijers-Heijboer, Hanne E J, Gille, Johan J P, Blok, Marinus J, Hoogerbrugge, Nicoline, Daly, Mary B, Andrulis, Irene L, Buys, Saundra S, John, Esther M, McLachlan, Sue-Anne, Friedlander, Michael, Tan, Yen Y, Osorio, Ana, Caldes, Trinidad, Jakubowska, Anna, Simard, Jacques, Singer, Christian F, Olah, Edith, Navratilova, Marie, Foretova, Lenka, Gerdes, Anne-Marie, Roos-Blom, Marie-José, Arver, Brita, Olsson, Håkan, Schmutzler, Rita K, Hopper, John L, Milne, Roger L, Easton, Douglas F, Van Leeuwen, Flora E, Rookus, Matti A, Andrieu, Nadine, Goldgar, David E

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Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells von Glykofridis, Iris E, Knol, Jaco C, Balk, Jesper A, Westland, Denise, Pham, Thang V, Piersma, Sander R, Lougheed, Sinéad M, Derakhshan, Sepide, Veen, Puck, Rooimans, Martin A, van Mil, Saskia E, Böttger, Franziska, Poddighe, Pino J, van de Beek, Irma, Drost, Jarno, Zwartkruis, Fried Jt, de Menezes, Renee X, Meijers-Heijboer, Hanne Ej, Houweling, Arjan C, Jimenez, Connie R, Wolthuis, Rob Mf

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Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers von COUCH, Fergus J, GAUDET, Mia M, MCGUFFOG, Lesley, BARROWDALE, Daniel, LEE, Andrew, HEALEY, Sue, SINILNIKOVA, Olga M, ANDRULIS, Irene L, OZCELIK, Hilmi, MULLIGAN, Anna Marie, THOMASSEN, Mads, GERDES, Anne-Marie, ANTONIOU, Antonis C, BIRK JENSEN, Uffe, SKYTTE, Anne-Bine, KRUSE, Torben A, CALIGO, Maria A, VON WACHENFELDT, Anna, BARBANY-BUSTINZA, Gisela, LOMAN, Niklas, SOLLER, Maria, EHRENCRONA, Hans, KARLSSON, Per, RAMUS, Susan J, NATHANSON, Katherine L, REBBECK, Timothy R, DOMCHEK, Susan M, JAKUBOWSKA, Ania, LUBINSKI, Jan, JAWORSKA, Katarzyna, DURDA, Katarzyna, ZLOWOCKA, Elzbieta, HUZARSKI, Tomasz, BYRSKI, Tomasz, KUCHENBAECKER, Karoline B, GRONWALD, Jacek, CYBULSKI, Cezary, GORSKI, Bohdan, OSORIO, Ana, DURAN, Mercedes, ISABEL TEJADA, Maria, BENITEZ, Javier, HAMANN, Ute, HOGERVORST, Frans B. L, OS, Theo A. Van, SOUCY, Penny, LEEUWEN, Flora E. Van, MEIJERS-HEIJBOER, Hanne E. J, WIJNEN, Juul, BLOK, Marinus J, KETS, Marleen, HOONING, Maartje J, OLDENBURG, Rogier A, AUSEMS, Margreet G. E. M, PEOCK, Susan, BEESLEY, Jonathan, XIAOQING CHEN, XIANSHU WANG, KIRCHHOFF, Tomas

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A Nonsynonymous Polymorphism in IRS1 Modifies Risk of Developing Breast and Ovarian Cancers in BRCA1 and Ovarian Cancer in BRCA2 Mutation Carriers von DING, Yuan C, MCGUFFOG, Lesley, KRISTOFFERSSON, Ulf, STENMARK-ASKMALM, Marie, MELIN, Beatrice, DOMCHEK, Susan M, NATHANSON, Katherine L, REBBECK, Timothy R, JAKUBOWSKA, Anna, LUBINSKI, Jan, JAWORSKA, Katarzyna, DURDA, Katarzyna, HEALEY, Sue, GRONWALD, Jacek, HUZARSKI, Tomasz, CYBULSKI, Cezary, BYRSKI, Tomasz, OSORIO, Ana, RAMONY CAJAL, Teresa, STAVROPOULOU, Alexandra V, BENITEZ, Javier, HAMANN, Ute, ROOKUS, Matti, FRIEDMAN, Eitan, AALFS, Cora M, DE LANE, Judith L, MEIJERS-HEIJBOER, Hanne E. J, OOSTERWIJK, Jan C, ASPEREN, Christi J. Van, GOMEZ GARCIA, Encarna B, HOOGERBRUGGE, Nicoline, JAGER, Agnes, DER LUIJT, Rob B. Van, EASTON, Douglas F, LAITMAN, Yael, PEOCK, Susan, FROST, Debra, ELLIS, Steve D, PLATTE, Radka, FINEBERG, Elena, EVANS, D. Gareth, LALLOO, Fiona, IZATT, Louise, EELES, Ros, ADLARD, Julian, PALUCH-SHIMON, Shani, DAVIDSON, Rosemarie, ECCLES, Diana, COLE, Trevor, COOK, Jackie, BREWER, Carole, TISCHKOWITZ, Marc, GODWIN, Andrew K, PATHAK, Harsh, STOPPA-LYONNET, Dominique, SINILNIKOVA, Olga M, KAUFMAN, Bella, LILJEGREN, Annelie, LINDBLOM, Annika, OLSSON, Hakan

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Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression : identification of a modifier of breast cancer... von Soucy, Penny, Kuchenbaeker, Karoline B, Pastinen, Tomi, Aittomaki, Kristiina, Arnold, Norbert, Arun, Banu K, Azzollini, Jacopo, Barjhoux, Laure, Barrowdale, Daniel, Berthet, Pascaline, Blok, Marinus J, Bonanni, Bernardo, Bradbury, Angela R, Buecher, Bruno, Caligo, Maria A, Chung, Wendy K, De Leeneer, Kim, Diez, Orland, Dolcetti, Riccardo, Eccles, Diana, Eeles, Ros, Ejlertsen, Bent, Engel, Christoph, Evans, D. Gareth, Foulkes, William D, Fountzilas, George, Friedman, Eitan, Frost, Debra, Ganschow, Pamela, Garber, Judy, Gerdes, Anne-Marie, Glendon, Gord, Goldgar, David E, Greene, Mark H, Hahnen, Eric, Hulick, Peter J, Imyanitov, Evgeny N, Isaacs, Claudine, Izatt, Louise, Janavicius, Ramunas, John, Esther M, Joseph, Vijai, Just, Walter, Kaczmarek, Katarzyna, Karlan, Beth Y, Kirk, Judy, Kriege, Mieke, Laitman, Yael, Laurent, Maite, Lazaro, Conxi, Leslie, Goska, Lester, Jenny, Lesueur, Fabienne, Loman, Niklas, Loud, Jennifer T, Manoukian, Siranoush, Mariani, Milena, Mazoyer, Sylvie, McGuffog, Lesley, Meijers-Heijboer, Hanne E. J, Mulligan, Anna Marie, Nathanson, Katherine L, Olopade, Olufunmilayo I, Osorio, Ana, Papi, Laura, Park, Sue Kyung, Pedersen, Inge Sokilde, Segura, Pedro Perez, Peterlongo, Paolo, Radice, Paolo, Rantala, Johanna, Rennert, Gad, Richardson, Andrea, Robson, Mark, Schmutzler, Rita Katharina, Sevenet, Nicolas, Shah, Payal D, Singer, Christian F, Slavin, Thomas P, Sokolowska, Johanna, Southey, Melissa, Spurdle, Amanda B, Stadler, Zsofia, Stoppa-Lyonnet, Dominique, Tea, Muy-Kheng, Teixeira, Manuel R, Teo, Soo-Hwang, Terry, Mary Beth, Tihomirova, Laima, Tognazzo, Silvia, Toland, Amanda Ewart, van den Ouweland, Ans M. W, van Rensburg, Elizabeth J, Varon-Mateeva, Raymonda, Wijnen, Juul T, Couch, Fergus J, Nord, Silje, Simard, Jacques, HEBON, [missing], KConFab Investigators, [missing]

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Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers von Im, Kate M., Kirchhoff, Tomas, Wang, Xianshu, Green, Todd, Chow, Clement Y., Korn, Joshua, Gaudet, Mia M., Fredericksen, Zachary, Shane Pankratz, V., Guiducci, Candace, Crenshaw, Andrew, McGuffog, Lesley, Kartsonaki, Christiana, Morrison, Jonathan, Healey, Sue, Sinilnikova, Olga M., Mai, Phuong L., Greene, Mark H., Piedmonte, Marion, Rubinstein, Wendy S., Hogervorst, Frans B., Rookus, Matti A., Collée, J. Margriet, Hoogerbrugge, Nicoline, Meijers-Heijboer, Hanne E. J., Van Roozendaal, Cees E., Perez-Segura, Pedro, Jakubowska, Anna, Huzarski, Tomasz, Blecharz, Paweł, Nevanlinna, Heli, Aittomäki, Kristiina, Lazaro, Conxi, Blanco, Ignacio, Barkardottir, Rosa B., D’Andrea, Emma, Devilee, Peter, Olopade, Olufunmilayo I., Peissel, Bernard, Bonanni, Bernardo, Peterlongo, Paolo, Singer, Christian F., Rennert, Gad, Lejbkowicz, Flavio, Andrulis, Irene L., Ozcelik, Hilmi, Toland, Amanda Ewart, Caligo, Maria Adelaide, Beattie, Mary S., Chan, Salina, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Phelan, Catherine, Narod, Steven, John, Esther M., Hopper, John L., Buys, Saundra S., Southey, Melissa C., Terry, Mary-Beth, Tung, Nadine, Hansen, Thomas v. O., Benitez, Javier, Weitzel, Jeffrey N., Garber, Judy, Hamann, Ute, Peock, Susan, Cook, Margaret, Oliver, Clare T., Frost, Debra, Eeles, Ros, Izatt, Louise, Paterson, Joan, Brewer, Carole, Hodgson, Shirley, Porteous, Mary, Walker, Lisa, Rogers, Mark T., Side, Lucy E., Godwin, Andrew K., Wappenschmidt, Barbara, Laitman, Yael, Deissler, Helmut, Varon-Mateeva, Raymonda, Preisler-Adams, Sabine, Kast, Karin, Venat-Bouvet, Laurence, Stoppa-Lyonnet, Dominique, Chenevix-Trench, Georgia, Easton, Douglas F., Klein, Robert J., Daly, Mark J., Friedman, Eitan, Dean, Michael, Clark, Andrew G., Altshuler, David M., Antoniou, Antonis C., Couch, Fergus J., Offit, Kenneth, Gold, Bert

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