The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies von Manry, Jérémy, Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Rosain, Jérémie, Philippot, Quentin, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Eto, Shohei, Garcia-Prat, Marina, Bizien, Lucy, Parra-Martínez, Alba, Yang, Rui, Haljasmägi, Liis, Migaud, Mélanie, Särekannu, Karita, Maslovskaja, Julia, de Prost, Nicolas, Tandjaoui-Lambiotte, Yacine, Luyt, Charles-Edouard, Amador-Borrero, Blanca, Gaudet, Alexandre, Poissy, Julien, Morel, Pascal, Richard, Pascale, Cognasse, Fabrice, Troya, Jesús, Trouillet-Assant, Sophie, Belot, Alexandre, Saker, Kahina, Garçon, Pierre, Rivière, Jacques G, Lagier, Jean-Christophe, Gentile, Stéphanie, Rosen, Lindsey B, Shaw, Elana, Morio, Tomohiro, Tanaka, Junko, Dalmau, David, Tharaux, Pierre-Louis, Sene, Damien, Stepanian, Alain, Mégarbane, Bruno, Triantafyllia, Vasiliki, Fekkar, Arnaud, Heath, James R, Franco, José Luis, Anaya, Juan-Manuel, Solé-Violán, Jordi, Imberti, Luisa, Biondi, Andrea, Bonfanti, Paolo, Castagnoli, Riccardo, Delmonte, Ottavia M, Zhang, Yu, Snow, Andrew L, Holland, Steven M, Biggs, Catherine M, Moncada-Vélez, Marcela, Arias, Andrés Augusto, Lorenzo, Lazaro, Boucherit, Soraya, Anglicheau, Dany, Planas, Anna M, Haerynck, Filomeen, Duvlis, Sotirija, Ozcelik, Tayfun, Keles, Sevgi, Bousfiha, Ahmed A, El Bakkouri, Jalila, Ramirez-Santana, Carolina, Paul, Stéphane, Pan-Hammarström, Qiang, Hammarström, Lennart, Dupont, Annabelle, Kurolap, Alina, Metz, Christine N, Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Ciceri, Fabio, Barreiros, Lucila A, Dominguez-Garrido, Elena, Vidigal, Mateus, Zatz, Mayana, van de Beek, Diederik, Sahanic, Sabina, Tancevski, Ivan, Stepanovskyy, Yurii, Boyarchuk, Oksana, Nukui, Yoko, Tsumura, Miyuki, Vidaur, Loreto, Tangye, Stuart G, Burrel, Sonia, Duffy, Darragh, Quintana-Murci, Lluis, Klocperk, Adam, Kann, Nelli Y, Shcherbina, Anna

Volltext

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths von Gervais, A, Philippot, Q, Manry, J, Michailidis, E, Parra-Martinez, A, Yang, R, Haljasmagi, L, Migaud, M, Sarekannu, K, Maslovskaja, J, de Prost, N, Tandjaoui-Lambiotte, Y, Poissy, J, Morel, P, Richard, P, Trouillet-Assant, S, Belot, A, Saker, K, Garcon, P, Lagier, JC, Gentile, S, Shaw, E, Morio, T, Tharaux, PL, Sene, D, Stepanian, A, Heath, JR, Franco, JL, Imberti, L, Biondi, A, Bonfanti, P, Castagnoli, R, Zhang, Y, Holland, SM, Biggs, CM, Lorenzo, L, Anglicheau, D, Haerynck, F, Nussbaum, RL, Keles, S, Bousfiha, AA, El Bakkouri, J, Ramirez-Santana, C, Pan-Hammarstrom, Q, Kurolap, A, Lampasona, V, Dominguez-Garrido, E, Vidigal, M, Zatz, M, van de Beek, D, Sahanic, S, Tancevski, I, Boyarchuk, O, Tangye, SG, Burrel, S, Duffy, D, Quintana-Murci, L, Klocperk, A, Shcherbina, A, Lau, YL, Chauvineau-Grenier, A, Venet, F, Monneret, G, Dyer, AH, Bourke, NM, Dorgham, K, Sedkaoui, SM, Rigo-Bonnin, R, Vinh, DC, Ostrowski, SR, Condino-Neto, A, Prando, C, Bondarenko, A, Spaan, AN, Gilardin, L, Fellay, J, Lyonnet, S, Lifton, RP, Mane, S, Anderson, MS, Andreakos, E, Pujol, A, Mogensen, TH, Mond, J, Debette, S, de Lamballerie, X, Gorochov, G, Solanich, X, Susen, S, Raoult, D, Gregersen, PK, Piemonti, L, Rodriguez-Gallego, C, Notarangelo, LD, Kisand, K, Okada, S, Rice, CM, Tiberghien, P, Zhang, Q, Abel, L

Volltext

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 or 16:02 individuals von Peel, Jessica N, Yang, Rui, Le Voyer, Tom, Gervais, Adrian, Rosain, Jérémie, Bastard, Paul, Behere, Anish, Cederholm, Axel, Bodansky, Aaron, Seeleuthner, Yoann, Conil, Clément, Ding, Jing-Ya, Lei, Wei-Te, Bizien, Lucy, Soudee, Camille, Migaud, Mélanie, Ogishi, Masato, Yatim, Ahmad, Lee, Danyel, Bohlen, Jonathan, Perpoint, Thomas, Perez, Laura, Messina, Fernando, Genet, Roxana, Karkowski, Ludovic, Blot, Mathieu, Lafont, Emmanuel, Toullec, Laurie, Goulvestre, Claire, Mehlal-Sedkaoui, Souad, Sallette, Jérôme, Martin, Fernando, Puel, Anne, Jouanguy, Emmanuelle, Anderson, Mark S, Landegren, Nils, Tiberghien, Pierre, Abel, Laurent, Boisson-Dupuis, Stéphanie, Bustamante, Jacinta, Ku, Cheng-Lung, Casanova, Jean-Laurent

Volltext

Neutralizing IFN-γ autoantibodies are rare and in HLA-DRB115:02 or 16:02 individuals von Peel, JN, Yang, R, Le, Voyer T, Gervais, A, Rosain, J, Bastard, P, Behere, A, Cederholm, A, Bodansky, A, Seeleuthner, Y

Volltext

Neutralizing IFN-[gamma] autoantibodies are rare and pathogenic in HLA-DRB115:02 or 16:02 individuals von Peel, Jessica N, Yang, Rui, Le Voyer, Tom, Gervais, Adrian, Rosain, Jeremie, Bastard, Paul, Behere, Anish, Cederholm, Axel, Bodansky, Aaron, Seeleuthner, Yoann, Conil, Clement, Ding, Jing-Ya, Lei, Wei-Te, Bizien, Lucy, Soudee, Camille, Migaud, Melanie, Ogishi, Masato, Yatim, Ahmad, Lee, Danyel, Bohlen, Jonathan, Perpoint, Thomas, Perez, Laura, Messina, Fernando, Genet, Roxana, Karkowski, Ludovic, Blot, Mathieu, Lafont, Emmanuel, Toullec, Laurie, Goulvestre, Claire, Mehlal-Sedkaoui, Souad, Sallette, Jerome, Martin, Fernando, Puel, Anne, Jouanguy, Emmanuelle, Anderson, Mark S, Landegren, Nils, Tiberghien, Pierre, Abel, Laurent, Boisson-Dupuis, Stephanie, Bustamante, Jacinta, Ku, Cheng-Lung, Casanova, Jean-Laurent

Volltext

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 or 16:02 individuals von Peel, Jessica N, Yang, Rui, Le Voyer, Tom, Gervais, Adrian, Rosain, Jérémie, Bastard, Paul, Behere, Anish, Cederholm, Axel, Bodansky, Aaron, Seeleuthner, Yoann, Conil, Clément, Ding, Jing-Ya, Lei, Wei-Te, Bizien, Lucy, Soudee, Camille, Migaud, Mélanie, Ogishi, Masato, Yatim, Ahmad, Lee, Danyel, Bohlen, Jonathan, Perpoint, Thomas, Perez, Laura, Messina, Fernando, Genet, Roxana, Karkowski, Ludovic, Blot, Mathieu, Lafont, Emmanuel, Toullec, Laurie, Goulvestre, Claire, Mehlal-Sedkaoui, Souad, Sallette, Jérôme, Martin, Fernando, Puel, Anne, Jouanguy, Emmanuelle, Du Sang, Etablissement, Anderson, Mark S, Landegren, Nils, Tiberghien, Pierre, Abel, Laurent, Boisson-Dupuis, Stéphanie, Bustamante, Jacinta, Ku, Cheng-Lung, Casanova, Jean-Laurent

Volltext

Autoantibodies against type I IFNs in patients with critical influenza pneumonia von Zhang, Qian, Pizzorno, Andrés, Gervais, Adrian, Manry, Jeremy, Rosain, Jérémie, Christodoulou, John, Bondarenko, Anastasiia, Morio, Tomohiro, Bonneaudeau, Brigitte, Cannet, Dorothée, Etablissement Français Du Sang Study Group, Pothier, Pierre, Gregersen, Peter K, Lemonnier, Sylvie, Padey, Blandine, Del Mar Muñoz Garcia, Maria, O'farrelly, Cliona, Lachaize, Morgane, Cooper, Megan A, Lucas, Carrie L, Romero Vázquez, Gloria María, Navarrete, Nicolás, Castagnoli, Riccardo, Maródi, László, Lau, Yu-lung, Pozzetto, Bruno, Renia, Laurent, Tancevski, Ivan, Ferres, Marcela, Franco, José Luis, Imai, Kohsuke, Souweine, Bertrand, Sánchez Cordero, Maria Jose, Perroquin, Magali, Abou Tayoun, Ahmad, Le Corre, Nicole, Snow, Andrew L, Tzourio, Christophe, Coeuret Pellicer, Mireille, Notarangelo, Luigi D, Javouhey, Etienne, Saker, Kahina, Covid Human Genetic Effort, Rombauts, Alexander, Zatz, Mayana, Kisand, Kai, Gallian, Pierre, Palomo, Virginia, Richard, Pascale, Ferreres, José, Tiberghien, Pierre, Reipi Inf Working Group, Goldberg, Marcel, Andreakos, Evangelos, Novelli, Antonio, Mehlal Sedkaoui, Souad, Sallette, Jérôme, Drolet, Beth A, Schwebel, Carole, Salamanca Rivera, Celia, Aiuti, Alessandro, 3C-Dijon Study, Debette, Stéphanie, Hamzeh Cognasse, Hind, Belot, Alexandre, Abel, Laurent, Abad Arranz, Maria, Meyts, Isabelle, Casanova, Jean-Laurent, Valiente, Adoración, El Baghdadi, Jamila, Balsera-manzanero, María, Hammarström, Lennart, Queromes, Gregory, Prando, Carolina, Aydillo, Teresa, Okamoto, Keisuke, Karamitros, Timokratis, Feys, Simon, Romero Oraa, Laura, Quintana Murci, Lluis, Hsieh, Elena W.Y, Tal, Galit, Fournet, Thomas, Patural, Hugues, Novelli, Giuseppe, Lyon Antigrippe Working Group, Arias, Andrés A, Jouanguy, Emmanuelle, Su, Helen C, Mogensen, Trine H, Casari, Giorgio, Ramaswamy, Sathishkumar, Abelenda Alonso, Gabriela, Fragkou, Paraskevi C, Vanderbeke, Lore, Biggs, Catherine M, Von Bernuth, Horst, Hagin, David, Bolze, Alexandre

Volltext

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths von Bastard, Paul, Le Voyer, Tom, Rosain, Jérémie, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Eto, Shohei, Haljasmägi, Liis, Migaud, Mélanie, Särekannu, Karita, Tandjaoui-Lambiotte, Yacine, Gaudet, Alexandre, Poissy, Julien, Morel, Pascal, Richard, Pascale, Troya, Jesus, Saker, Kahina, Gentile, Stéphanie, Shaw, Elana, Morio, Tomohiro, Dalmau, David, Sene, Damien, Stepanian, Alain, Megarbane, Bruno, Fekkar, Arnaud, Heath, James R, Anaya, Juan-Manuel, Solé-Violán, Jordi, Bonfanti, Paolo, Castagnoli, Riccardo, Delmonte, Ottavia M, Zhang, Yu, Holland, Steven M, Arias, Andrés Augusto, Lorenzo, Lazaro, Anglicheau, Dany, Planas, Anna M, Ozcelik, Tayfun, Keles, Sevgi, El Bakkouri, Jalila, Ramirez-Santana, Carolina, Pan-Hammarström, Qiang, Hammarström, Lennart, Metz, Christine N, Aiuti, Alessandro, Casari, Giorgio, Ciceri, Fabio, Vidigal, Mateus, Sahanic, Sabina, Stepanovskyy, Yurii, Tsumura, Miyuki, Duffy, Darragh, Quintana-Murci, Lluis, Kann, Nelli Y, Shcherbina, Anna, Lau, Yu-Lung, Koning, Rutger, Nussenzweig, Michel C, Baris-Feldman, Hagit, Wauters, Joost, Bourke, Nollaig M, Sharif-Askari, Narjes Saheb, Mehlal Sedkaoui, Souad, AlKhater, Suzan, Morandeira, Francisco, Vinh, Donald C, Condino-Neto, Antonio, Spaan, András N, Bilguvar, Kaya, Lifton, Richard P, Anderson, Mark S, Boisson, Bertrand, Zhang, Shen-Ying, Andreakos, Evangelos, Peterson, Pärt, Rowen, Lee, Duval, Xavier, Mentré, France, Zins, Marie, Soler-Palacin, Pere, Susen, Sophie, Martinez-Picado, Javier, Raoult, Didier, Piemonti, Lorenzo, Notarangelo, Luigi D, Okada, Satoshi, Rice, Charles M, Cobat, Aurélie, Abel, Laurent, HGID Lab, [missing], COVID-STORM Clinicians, [missing], NH-COVAIR Study Group, [missing], Danish Blood Donor Study, [missing], French COVID Cohort Study Group, [missing], The Milieu Intérieur Consortium, [missing], CoV-Contact Cohort, [missing], Amsterdam UMC Covid-19 Biobank Investigators, [missing], COVID Human Genetic Effort, [missing], Van Braeckel, Eva, Bosteels, Cedric, Hoste, Eric

Volltext

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 or 16:02 individuals von Peel, Jessica N, Yang, Rui, Le Voyer, Tom, Gervais, Adrian, Rosain, Jérémie, Bastard, Paul, Behere, Anish, Cederholm, Axel, Bodansky, Aaron, Seeleuthner, Yoann, Conil, Clément, Ding, Jing-Ya, Lei, Wei-Te, Bizien, Lucy, Soudee, Camille, Migaud, Mélanie, Ogishi, Masato, Yatim, Ahmad, Lee, Danyel, Bohlen, Jonathan, Perpoint, Thomas, Perez, Laura, Messina, Fernando, Genet, Roxana, Karkowski, Ludovic, Blot, Mathieu, Lafont, Emmanuel, Toullec, Laurie, Goulvestre, Claire, Mehlal-Sedkaoui, Souad, Sallette, Jérôme, Martin, Fernando, Puel, Anne, Jouanguy, Emmanuelle, Anderson, Mark S, Landegren, Nils, Tiberghien, Pierre, Abel, Laurent, Boisson-Dupuis, Stéphanie, Bustamante, Jacinta, Ku, Cheng-Lung, Casanova, Jean-Laurent

Volltext bestellen