One‐thousand‐and‐one substrates of protein kinase CK2? von Meggio, Flavio, Pinna, Lorenzo A.

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Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight von Lolli, Graziano, Cozza, Giorgio, Mazzorana, Marco, Tibaldi, Elena, Cesaro, Luca, Donella-Deana, Arianna, Meggio, Flavio, Venerando, Andrea, Franchin, Cinzia, Sarno, Stefania, Battistutta, Roberto, Pinna, Lorenzo A

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Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer von Battistutta, Roberto, Cozza, Giorgio, Pierre, Fabrice, Papinutto, Elena, Lolli, Graziano, Sarno, Stefania, O’Brien, Sean E, Siddiqui-Jain, Adam, Haddach, Mustapha, Anderes, Kenna, Ryckman, David M, Meggio, Flavio, Pinna, Lorenzo A

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The selectivity of inhibitors of protein kinase CK2: an update von Pagano, Mario A, Bain, Jenny, Kazimierczuk, Zygmunt, Sarno, Stefania, Ruzzene, Maria, Di Maira, Giovanni, Elliott, Matthew, Orzeszko, Andrzej, Cozza, Giorgio, Meggio, Flavio, Pinna, Lorenzo A

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Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 von Cozza, Giorgio, Mazzorana, Marco, Papinutto, Elena, Bain, Jenny, Elliott, Matthew, di Maira, Giovanni, Gianoncelli, Alessandra, Pagano, Mario A, Sarno, Stefania, Ruzzene, Maria, Battistutta, Roberto, Meggio, Flavio, Moro, Stefano, Zagotto, Giuseppe, Pinna, Lorenzo A

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Coumarin as Attractive Casein Kinase 2 (CK2) Inhibitor Scaffold: An Integrate Approach To Elucidate the Putative Binding Motif and Explain Structure–Activity Relationships von Chilin, Adriana, Battistutta, Roberto, Bortolato, Andrea, Cozza, Giorgio, Zanatta, Samuele, Poletto, Giorgia, Mazzorana, Marco, Zagotto, Giuseppe, Uriarte, Eugenio, Guiotto, Adriano, Pinna, Lorenzo A, Meggio, Flavio, Moro, Stefano

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Roscovitine Targets, Protein Kinases and Pyridoxal Kinase[boxs] von Bach, Stéphane, Knockaert, Marie, Reinhardt, Jens, Lozach, Olivier, Schmitt, Sophie, Baratte, Blandine, Koken, Marcel, Coburn, Stephen P., Tang, Lin, Jiang, Tao, Liang, Dong-cai, Galons, Hervé, Dierick, Jean-Francois, Pinna, Lorenzo A., Meggio, Flavio, Totzke, Frank, Schächtele, Christoph, Lerman, Andrea S., Carnero, Amancio, Wan, Yongqin, Gray, Nathanael, Meijer, Laurent

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The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks von Loizou, Joanna I., El-Khamisy, Sherif F., Zlatanou, Anastasia, Moore, David J., Chan, Douglas W., Qin, Jun, Sarno, Stefania, Meggio, Flavio, Pinna, Lorenzo A., Caldecott, Keith W.

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Optimization of Protein Kinase CK2 Inhibitors Derived from 4,5,6,7-Tetrabromobenzimidazole von Pagano, Mario A, Andrzejewska, Mariola, Ruzzene, Maria, Sarno, Stefania, Cesaro, Luca, Bain, Jenny, Elliott, Matthew, Meggio, Flavio, Kazimierczuk, Zygmunt, Pinna, Lorenzo A

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Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 (‘casein kinase-2’) von Sarno, Stefania, Reddy, Helen, Meggio, Flavio, Ruzzene, Maria, Davies, Stephen P., Donella-Deana, Arianna, Shugar, David, Pinna, Lorenzo A.

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Identification of Ellagic Acid as Potent Inhibitor of Protein Kinase CK2:  A Successful Example of a Virtual Screening Application von Cozza, Giorgio, Bonvini, Paolo, Zorzi, Elisa, Poletto, Giorgia, Pagano, Mario A., Sarno, Stefania, Donella-Deana, Arianna, Zagotto, Giuseppe, Rosolen, Angelo, Pinna, Lorenzo A., Meggio, Flavio, Moro, Stefano

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Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors von Pagano, Mario A., Poletto, Giorgia, Di Maira, Giovanni, Cozza, Giorgio, Ruzzene, Maria, Sarno, Stefania, Bain, Jenny, Elliott, Matthew, Moro, Stefano, Zagotto, Giuseppe, Meggio, Flavio, Pinna, Lorenzo A.

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Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA) von Sarno, Stefania, de Moliner, Erika, Ruzzene, Maria, Pagano, Mario A, Battistutta, Roberto, Bain, Jenny, Fabbro, Doriano, Schoepfer, Joseph, Elliott, Matthew, Furet, Pascal, Meggio, Flavio, Zanotti, Giuseppe, Pinna, Lorenzo A

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Toward the rational design of protein kinase casein kinase-2 inhibitors von Sarno, Stefania, Moro, Stefano, Meggio, Flavio, Zagotto, Giuseppe, Dal Ben, Diego, Ghisellini, Paola, Battistutta, Roberto, Zanotti, Giuseppe, Pinna, Lorenzo A

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A Noncanonical Sequence Phosphorylated by Casein Kinase 1 in β-Catenin May Play a Role in Casein Kinase 1 Targeting of Important Signaling Proteins von Marin, Oriano, Bustos, Victor H., Cesaro, Luca, Meggio, Flavio, Pagano, Mario A., Antonelli, Marcelo, Allende, Catherine C., Pinna, Lorenzo A., Allende, Jorge E.

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Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization von An, Rong, da Silva Xavier, Gabriela, Semplici, Francesca, Vakhshouri, Saharnaz, Hao, Huai-Xiang, Rutter, Jared, Pagano, Mario A., Meggio, Flavio, Pinna, Lorenzo A., Rutter, Guy A.

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Inhibition of Protein Kinase CK2 by Condensed Polyphenolic Derivatives. An in Vitro and in Vivo Study von Meggio, Flavio, Pagano, Mario A, Moro, Stefano, Zagotto, Giuseppe, Ruzzene, Maria, Sarno, Stefania, Cozza, Giorgio, Bain, Jenny, Elliott, Matthew, Deana, Arianna Donella, Brunati, Anna Maria, Pinna, Lorenzo A

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CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with β-TrCP and enhances β-catenin degradation von SEMPLICI, Francesca, MEGGIO, Flavio, PINNA, Lorenzo A, OLIVIERO, Salvatore

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A Modified KESTREL Search Reveals a Basophilic Substrate Consensus for the Saccharomyces cerevisiae Npr1 Protein Kinase von Gander, Stefan, Martin, Dietmar, Hauri, Simon, Moes, Suzette, Poletto, Giorgia, Pagano, Mario A, Marin, Oriano, Meggio, Flavio, Jenoe, Paul

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Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 von Gianoncelli, Alessandra, Cozza, Giorgio, Orzeszko, Andrzej, Meggio, Flavio, Kazimierczuk, Zygmunt, Pinna, Lorenzo A.

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