Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092 von Yu, Yi, Savage, Ronald E, Eathiraj, Sudharshan, Meade, Justin, Wick, Michael J, Hall, Terence, Abbadessa, Giovanni, Schwartz, Brian

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NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in intestinal epithelial cells von Mazzone, Ryan J., Winsor, Nathaniel J., Li, Lu Yi, Barry, Kristian T., Ranger, Adrienne, Goyal, Shawn, Meade, Justin J., Bruce, Jessica, Philpott, Dana J., Mogridge, Jeremy, Girardin, Stephen E.

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Activation of the NLRP1B inflammasome by caspase-8 von Meade, Justin J., Stuart, Sarah, Neiman-Zenevich, Jana, Krustev, Christian, Girardin, Stephen E., Mogridge, Jeremy

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Abstract B185: ARQ 092 enhances the efficacy of paclitaxel, lapatinib, trastuzumab, trametinib, and ARQ 087 both in cancer cell lines and mouse xenograft cancer models von Yu, Yi, Meade, Justin, Wick, Michael J., Terence, Hall, Eathiraj, Sudhi, Schwartz, Brian, Abbadessa, Giovanni

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Abstract 4760: Efficacy of EGFR/HER2 duel-kinase inhibitors in PDX models harboring known and novel HER2-mutations von Wick, Michael J., Farley, Monica, Vaught, Teresa, Meade, Justin, Glassman, Michaels, Moriarty, Alyssa, Tolcher, Anthony W., Rasco, Drew, Patnaik, Amita, Papadopoulos, Kyriakos P.

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Abstract 4760: Efficacy of EGFRHER2 duel-kinase inhibitors in PDX models harboring known and novel HER2-mutations von Wick, Michael J, Farley, Monica, Vaught, Teresa, Meade, Justin, Glassman, Michaels, Moriarty, Alyssa, Tolcher, Anthony W, Rasco, Drew, Patnaik, Amita, Papadopoulos, Kyriakos P

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Abstract B181: Association of AKT1E17K and PIK3CAH1047R mutations with efficacy of ARQ 092 in vitro, in vivo and in patients von Abbadessa, Giovanni, Yu, Yi, Eathiraj, Sudharshan, Meade, Justin, Wick, Michael J., Tolcher, Anthony, Papadopoulos, Kyri, Saleh, Mansoor, Sachdev, Jasgit, Chai, Feng, Schwartz, Brian

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Abstract C74: Establishment and characterization of a HER2-positive, TDM1-resistant PDX breast model von Wick, Michael J., Vaught, Teresa L., Meade, Justin, Farley, Monica, Diaz, Armando, Tolcher, Anthony W., Rasco, Drew W., Patnaik, Amita, Beeram, Murali, Papadopoulos, Kyriakos P.

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Abstract 2985: In vivo evaluation of regorafenib and liposomal-doxorubicin in a panel of low passage uterine START-PDX tumor models von Meade, Justin, Wick, Michael J., Vaught, Teresa, Gamez, Lizette, Chavez, Roger, Tolcher, Anthony, Rasco, Drew, Patnaik, Amita, White, Allan J., Papadopoulos, Kyriakos

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Abstract 1223: Establishment, characterization and evaluation of a panel of head and neck patient-derived xenograft (PDX) models von Wick, Michael J., Vaught, Teresa, Gamez, Lizette, Diaz, Armando, Meade, Justin, Farley, Monica, Moriarty, Alyssa, Carlile, Jennifer, Tolcher, Anthony, Rasco, Drew, Patnaik, Amita, Newman, Richard, Papadopoulos, Kyriakos

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Abstract C10: Establishment and characterization of melanoma patient-derived xenograft (PDX) model sets: correlation with clinical response and progression using serial biopsy samp... von Wick, Michael J., Meade, Justin, Brown, Jennifer, Vaught, Teresa L., Tolcher, Anthony W., Gamez, Lizette, Rasco, Drew, Patnaik, Amita, Drengler, Ronald, Papadopoulos, Kyriakos P.

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Abstract A106: Utilization of low passage adenoid cystic carcinoma (ACC) models to identify novel therapies von Meade, Justin, Wick, Michael J., Vaught, Teresa L., Carlile, Jennifer, Tolcher, Anthony W., Rasco, Drew, Patnaik, Amita, Kaufman, Jeffrey, Moskaluk, Chris, Papadopoulos, Kyriakos P.

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Abstract C104: Preclinical sensitivity of low and high-HER2 expressing START-PDX breast models to T-DM1 and effects of HER3 expression on drug antitumor activity von Wick, Michael J., Brown, Jennifer, Vaught, Teresa L., Meade, Justin, Tolcher, Anthony W., Rasco, Drew, Patnaik, Amita, Lang, Amy, Beeram, Murali, Papadopoulos, Kyriakos P.

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Abstract 2037: Establishment and characterization of paired mutant B-raf, vemurafenib-sensitive and -resistant patient-derived xenograft models von Wick, Michael J., Vaught, Teresa L., Gamez, Lizette, Meade, Justin, Carden, Skylar, Tolcher, Anthony W., Rasco, Drew W., Patnaik, Amita, Miller, Alexander, Drengler, Ronald, Papadopoulos, Kyriakos P.

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A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification von Iverson, Sonya V., Eriksson, Sofi, Xu, Jianqiang, Prigge, Justin R., Talago, Emily A., Meade, Tesia A., Meade, Erin S., Capecchi, Mario R., Arnér, Elias S.J., Schmidt, Edward E.

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Human-modified landscapes provide key foraging areas for a threatened flying mammal: The grey-headed flying-fox von Yabsley, Samantha H., Meade, Jessica, Martin, John M., Welbergen, Justin A.

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Extreme mobility of the world's largest flying mammals creates key challenges for management and conservation von Welbergen, Justin A., Meade, Jessica, Field, Hume E., Edson, Daniel, McMichael, Lee, Shoo, Luke P., Praszczalek, Jenny, Smith, Craig, Martin, John M.

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Using weather radar to monitor the number, timing and directions of flying-foxes emerging from their roosts von Meade, Jessica, van der Ree, Rodney, Stepanian, Phillip M., Westcott, David A., Welbergen, Justin A.

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Fast food in the city? Nomadic flying-foxes commute less and hang around for longer in urban areas von Meade, Jessica, Martin, John M, Welbergen, Justin A

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Rodeo Thumb: To Replant or Not von Davis, Justin J., Meade, Anna E., Cochran, Lindsey, Sammer, Douglas M., Zhang, Andrew Y.

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