Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells von Gennaro, Victoria J., Stanek, Timothy J., Peck, Amy R., Sun, Yunguang, Wang, Feng, Qie, Shuo, Knudsen, Karen E., Rui, Hallgeir, Butt, Tauseef, Diehl, J. Alan, McMahon, Steven B.

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Myc Regulates a Transcriptional Program That Stimulates Mitochondrial Glutaminolysis and Leads to Glutamine Addiction von Wise, David R., DeBerardinis, Ralph J., Mancuso, Anthony, Sayed, Nabil, Zhang, Xiao-Yong, Pfeiffer, Harla K., Nissim, Ilana, Daikhin, Evgueni, Yudkoff, Marc, McMahon, Steven B., Thompson, Craig B.

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Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation von Petruk, Svetlana, Cai, Jingli, Sussman, Robyn, Sun, Guizhi, Kovermann, Sina K., Mariani, Samanta A., Calabretta, Bruno, McMahon, Steven B., Brock, Hugh W., Iacovitti, Lorraine, Mazo, Alexander

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Acetylation of the p53 DNA-Binding Domain Regulates Apoptosis Induction von Sykes, Stephen M., Mellert, Hestia S., Holbert, Marc A., Li, Keqin, Marmorstein, Ronen, Lane, William S., McMahon, Steven B.

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Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase von Aggarwal, Priya, Vaites, Laura Pontano, Kim, Jong Kyong, Mellert, Hestia, Gurung, Buddha, Nakagawa, Hiroshi, Herlyn, Meenhard, Hua, Xianxin, Rustgi, Anil K., McMahon, Steven B., Diehl, J. Alan

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Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates von Farkas, Marina, Hashimoto, Hideharu, Bi, Yingtao, Davuluri, Ramana V., Resnick-Silverman, Lois, Manfredi, James J., Debler, Erik W., McMahon, Steven B.

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The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression von Zhang, Xiao-Yong, Varthi, Maya, Sykes, Stephen M., Phillips, Charles, Warzecha, Claude, Zhu, Wenting, Wyce, Anastasia, Thorne, Alan W., Berger, Shelley L., McMahon, Steven B.

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The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer von Barta, Julie A, Pauley, Kristen, Kossenkov, Andrew V, McMahon, Steven B

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USP22 Functions as an Oncogenic Driver in Prostate Cancer by Regulating Cell Proliferation and DNA Repair von McCann, Jennifer J., Vasilevskaya, Irina A., Neupane, Neermala Poudel, Shafi, Ayesha A., McNair, Christopher, Dylgjeri, Emanuela, Mandigo, Amy C., Schiewer, Matthew, Schrecengost, Randy S., Gallagher, Peter, Stanek, Timothy J., Mcmahon, Steven B., Berman-Booty, Lisa D., Ostrander, William F., Knudsen, Karen E.

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Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53 von Charvet, Céline, Wissler, Manuela, Brauns-Schubert, Prisca, Wang, Shang-Jui, Tang, Yi, Sigloch, Florian C., Mellert, Hestia, Brandenburg, Martin, Lindner, Silke E., Breit, Bernhard, Green, Douglas R., McMahon, Steven B., Borner, Christoph, Gu, Wei, Maurer, Ulrich

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Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC von Gennaro, Victoria J, Wedegaertner, Helen, McMahon, Steven B

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The Epigenetic Modifier Ubiquitin-specific Protease 22 (USP22) Regulates Embryonic Stem Cell Differentiation via Transcriptional Repression of Sex-determining Region Y-box 2 (SOX2) von Sussman, Robyn T., Stanek, Timothy J., Esteso, Paul, Gearhart, John D., Knudsen, Karen E., McMahon, Steven B.

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USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression von SCHRECENGOST, Randy S, DEAN, Jeffry L, VISAKORPI, Tapio, DEMARZO, Angelo M, MCMAHON, Steven B, KNUDSEN, Karen E, GOODWIN, Jonathan F, SCHIEWER, Matthew J, URBAN, Mark W, STANEK, Timothy J, SUSSMAN, Robyn T, HICKS, Jessica L, BIRBE, Ruth C, DRAGANOVA-TACHEVA, Rossitza A

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MYC and the control of apoptosis von McMahon, Steven B

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p53: The TRiC Is Knowing When to Fold ‘Em von Monteith, Jessica, McMahon, Steven B.

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USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A von Zhang, Xiao-yong, Pfeiffer, Harla, Thorne, Alan, McMahon, Steven B.

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A High-Confidence Interaction Map Identifies SIRT1 as a Mediator of Acetylation of USP22 and the SAGA Coactivator Complex von Armour, Sean M., Bennett, Eric J., Braun, Craig R., Zhang, Xiao-Yong, McMahon, Steven B., Gygi, Steven P., Harper, J. Wade, Sinclair, David A.

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Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells von KE CHEN, KONGMING WU, LISANTI, Michael P, TOZEREN, Aydin, TANES, Ceylan, ADDYA, Sankar, GORMLEY, Michael, CHENGUANG WANG, MCMAHON, Steven B, PESTELL, Richard G, SHAOXIN CAI, WEI ZHANG, JIE ZHOU, JING WANG, ERTEL, Adam, ZHIPING LI, RUI, Hallgeir, QUONG, Andrew

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MYST protein acetyltransferase activity requires active site lysine autoacetylation von Yuan, Hua, Rossetto, Dorine, Mellert, Hestia, Dang, Weiwei, Srinivasan, Madhusudan, Johnson, Jamel, Hodawadekar, Santosh, Ding, Emily C, Speicher, Kaye, Abshiru, Nebiyu, Perry, Rocco, Wu, Jiang, Yang, Chao, Zheng, Y George, Speicher, David W, Thibault, Pierre, Verreault, Alain, Johnson, F Bradley, Berger, Shelley L, Sternglanz, Rolf, McMahon, Steven B, Côté, Jacques, Marmorstein, Ronen

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Acetylation of the DNA Binding Domain Regulates Transcription-independent Apoptosis by p53 von Sykes, Stephen M., Stanek, Timothy J., Frank, Amanda, Murphy, Maureen E., McMahon, Steven B.

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