Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors von GRAY, Steven J, FOTI, Stacey B, SCHWARTZ, Joel W, BACHABOINA, Lavanya, TAYLOR-BLAKE, Bonnie, COLEMAN, Jennifer, EHLERS, Michael D, ZYLKA, Mark J, MCCOWN, Thomas J, SAMULSKI, R. Jude

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N -acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase von Francis, Jeremy S., PhD, Wojtas, Ireneusz, PhD, Markov, Vladimir, MD, Gray, Steven J., PhD, McCown, Thomas J., PhD, Samulski, R. Jude, PhD, Bilaniuk, Larissa T., MD, Wang, Dah-Jyuu, PhD, De Vivo, Darryl C., MD, Janson, Christopher G., MD, Leone, Paola, PhD

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Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles von Li, Wuping, Asokan, Aravind, Wu, Zhijian, Van Dyke, Terry, DiPrimio, Nina, Johnson, Jarrod S, Govindaswamy, Lakshmanan, Agbandje-McKenna, Mavis, Leichtle, Stefan, Eugene Redmond Jr, D, McCown, Thomas J, Petermann, Kimberly B, Sharpless, Norman E, Samulski, Richard J

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Mutagenesis of Adeno-Associated Virus Type 2 Capsid Protein VP1 Uncovers New Roles for Basic Amino Acids in Trafficking and Cell-Specific Transduction von Johnson, Jarrod S, Li, Chengwen, DiPrimio, Nina, Weinberg, Marc S, McCown, Thomas J, Samulski, R Jude

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Current prospects and challenges for epilepsy gene therapy von Weinberg, Marc S., McCown, Thomas J.

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AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo von Powell, Sara K., Samulski, R. Jude, McCown, Thomas J.

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Adeno-associated virus (AAV) gene therapy for neurological disease von Weinberg, Marc S., Samulski, R. Jude, McCown, Thomas J.

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Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility von Weinberg, Marc S., Blake, Bonita L., McCown, Thomas J.

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Treatment Strategies Targeting Excess Hippocampal Activity Benefit Aged Rats with Cognitive Impairment von Koh, Ming Teng, Haberman, Rebecca P, Foti, Stacey, McCown, Thomas J, Gallagher, Michela

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Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo von McCown, Thomas J

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Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons von Weinberg, Marc S., Criswell, Hugh E., Powell, Sara K., Bhatt, Aadra P., McCown, Thomas J.

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Generation of a Stable Cell Line Producing High-Titer Self-Inactivating Lentiviral Vectors von Xu, Kailin, Ma, Hong, McCown, Thomas J., Verma, Inder M., Kafri, Tal

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Adeno-Associated Virus Capsid-Promoter Interactions in the Brain Translate from Rat to the Nonhuman Primate von Bohlen, Martin O, McCown, Thomas J, Powell, Sara K, El-Nahal, Hala G, Daw, Tierney, Basso, Michele A, Sommer, Marc A, Samulski, R Jude

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Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB) von Gray, Steven J, Blake, Bonita L, Criswell, Hugh E, Nicolson, Sarah C, Samulski, R Jude, McCown, Thomas J

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Neuropeptide Y signaling modulates the expression of ethanol-induced behavioral sensitization in mice von Hayes, Dayna M., Fee, Jon R., McCown, Thomas J., Knapp, Darin J., Breese, George R., Cubero, Inmaculada, Carvajal, Francisca, Lerma-Cabrera, Jose Manuel, Navarro, Montserrat, Thiele, Todd E.

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Therapeutic Liabilities of in Vivo Viral Vector Tropism: Adeno-Associated Virus Vectors, NMDAR1 Antisense, and Focal Seizure Sensitivity von Haberman, Rebecca P., Criswell, Hugh E., Snowdy, Stephen, Ming, Zhen, Breese, George R., Samulski, R.Jude, McCown, Thomas J.

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Adeno-Associated Virus Vector-Mediated Expression and Constitutive Secretion of Galanin Suppresses Limbic Seizure Activity von McCown, Thomas J.

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Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administ... von Cook, Jason B, Werner, David F, Maldonado-Devincci, Antoniette M, Leonard, Maggie N, Fisher, Kristen R, O'Buckley, Todd K, Porcu, Patrizia, McCown, Thomas J, Besheer, Joyce, Hodge, Clyde W, Morrow, A Leslie

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Overexpression of the Steroidogenic Enzyme Cytochrome P450 Side Chain Cleavage in the Ventral Tegmental Area Increases 3 alpha ,5 alpha -THP and Reduces Long-Term Operant Ethanol S... von Cook, Jason B, Werner, David F, Maldonado-Devincci, Antoniette M, Leonard, Maggie N, Fisher, Kristen R, O'Buckley, Todd K, Porcu, Patrizia, McCown, Thomas J, Besheer, Joyce, Hodge, Clyde W, Morrow, A Leslie

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Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion von McCown, Thomas J, Haberman, Rebecca P, Samulski, R Jude

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