Exposing the exposures responsible for type 2 diabetes and obesity von Franks, Paul W., McCarthy, Mark I.

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Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine von Udler, Miriam S, McCarthy, Mark I, Florez, Jose C, Mahajan, Anubha

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10 Years of GWAS Discovery: Biology, Function, and Translation von Visscher, Peter M., Wray, Naomi R., Zhang, Qian, Sklar, Pamela, McCarthy, Mark I., Brown, Matthew A., Yang, Jian

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Five Years of GWAS Discovery von VISSCHER, Peter M, BROWN, Matthew A, MCCARTHY, Mark I, JIAN YANG

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Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases von Sanna, Serena, van Zuydam, Natalie R., Mahajan, Anubha, Kurilshikov, Alexander, Vich Vila, Arnau, Võsa, Urmo, Mujagic, Zlatan, Masclee, Ad A. M., Jonkers, Daisy M. A. E., Oosting, Marije, Joosten, Leo A. B., Netea, Mihai G., Franke, Lude, Zhernakova, Alexandra, Fu, Jingyuan, Wijmenga, Cisca, McCarthy, Mark I.

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Detection of human adaptation during the past 2000 years von Field, Yair, Boyle, Evan A, Telis, Natalie, Gao, Ziyue, Gaulton, Kyle J., Golan, David, Yengo, Loic, Rocheleau, Ghislain, Froguel, Philippe, McCarthy, Mark I., Pritchard, Jonathan K.

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Using human genetics to understand the disease impacts of testosterone in men and women von Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R. B.

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The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines von Eizirik, Décio L, Sammeth, Michael, Bouckenooghe, Thomas, Bottu, Guy, Sisino, Giorgia, Igoillo-Esteve, Mariana, Ortis, Fernanda, Santin, Izortze, Colli, Maikel L, Barthson, Jenny, Bouwens, Luc, Hughes, Linda, Gregory, Lorna, Lunter, Gerton, Marselli, Lorella, Marchetti, Piero, McCarthy, Mark I, Cnop, Miriam

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Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) von Chung, Wendy K., Erion, Karel, Florez, Jose C., Hattersley, Andrew T., Hivert, Marie-France, Lee, Christine G., McCarthy, Mark I., Nolan, John J., Norris, Jill M., Pearson, Ewan R., Philipson, Louis, McElvaine, Allison T., Cefalu, William T., Rich, Stephen S., Franks, Paul W.

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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation von Gamazon, Eric R., Segrè, Ayellet V., van de Bunt, Martijn, Wen, Xiaoquan, Xi, Hualin S., Hormozdiari, Farhad, Ongen, Halit, Konkashbaev, Anuar, Derks, Eske M., Aguet, François, Quan, Jie, Nicolae, Dan L., Eskin, Eleazar, Kellis, Manolis, Getz, Gad, McCarthy, Mark I., Dermitzakis, Emmanouil T., Cox, Nancy J., Ardlie, Kristin G.

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Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution von Mägi, Reedik, Horikoshi, Momoko, Sofer, Tamar, Mahajan, Anubha, Kitajima, Hidetoshi, Franceschini, Nora, McCarthy, Mark I, Morris, Andrew P

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A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies von Lehne, Benjamin, Drong, Alexander W, Loh, Marie, Zhang, Weihua, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Scott, James, Jarvelin, Marjo-Riitta, Elliott, Paul, McCarthy, Mark I, Kooner, Jaspal S, Chambers, John C

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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population von Bell, Jordana T, Tsai, Pei-Chien, Yang, Tsun-Po, Pidsley, Ruth, Nisbet, James, Glass, Daniel, Mangino, Massimo, Zhai, Guangju, Zhang, Feng, Valdes, Ana, Shin, So-Youn, Dempster, Emma L, Murray, Robin M, Grundberg, Elin, Hedman, Asa K, Nica, Alexandra, Small, Kerrin S, Dermitzakis, Emmanouil T, McCarthy, Mark I, Mill, Jonathan, Spector, Tim D, Deloukas, Panos

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The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease von Moutsianas, Loukas, Agarwala, Vineeta, Fuchsberger, Christian, Flannick, Jason, Rivas, Manuel A, Gaulton, Kyle J, Albers, Patrick K, McVean, Gil, Boehnke, Michael, Altshuler, David, McCarthy, Mark I

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The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis von van de Bunt, Martijn, Gaulton, Kyle J, Parts, Leopold, Moran, Ignasi, Johnson, Paul R, Lindgren, Cecilia M, Ferrer, Jorge, Gloyn, Anna L, McCarthy, Mark I

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Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements von Grundberg, Elin, Meduri, Eshwar, Sandling, Johanna K., Hedman, Åsa K., Keildson, Sarah, Buil, Alfonso, Busche, Stephan, Yuan, Wei, Nisbet, James, Sekowska, Magdalena, Wilk, Alicja, Barrett, Amy, Small, Kerrin S., Ge, Bing, Caron, Maxime, Shin, So-Youn, Ahmadi, Kourosh R., Ainali, Chrysanthi, Barrett, Amy, Bataille, Veronique, Bell, Jordana T., Buil, Alfonso, Deloukas, Panos, Dermitzakis, Emmanouil T., Dimas, Antigone S., Durbin, Richard, Glass, Daniel, Grundberg, Elin, Hassanali, Neelam, Hedman, Åsa K., Ingle, Catherine, Knowles, David, Krestyaninova, Maria, Lindgren, Cecilia M., Lowe, Christopher E., McCarthy, Mark I., Meduri, Eshwar, di Meglio, Paola, Min, Josine L., Montgomery, Stephen B., Nestle, Frank O., Nica, Alexandra C., Nisbet, James, O’Rahilly, Stephen, Parts, Leopold, Potter, Simon, Sandling, Johanna, Sekowska, Magdalena, Shin, So-Youn, Small, Kerrin S., Soranzo, Nicole, Spector, Tim D., Surdulescu, Gabriela, Travers, Mary E., Tsaprouni, Loukia, Tsoka, Sophia, Wilk, Alicja, Yang, Tsun-Po, Zondervan, Krina T., Lathrop, Mark, Dermitzakis, Emmanouil T., McCarthy, Mark I., Spector, Timothy D., Bell, Jordana T., Deloukas, Panos

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Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits von Yang, Jian, Ferreira, Teresa, Morris, Andrew P, Medland, Sarah E, Madden, Pamela A F, Heath, Andrew C, Martin, Nicholas G, Montgomery, Grant W, Weedon, Michael N, Loos, Ruth J, Frayling, Timothy M, McCarthy, Mark I, Hirschhorn, Joel N, Goddard, Michael E, Visscher, Peter M

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Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications von Pinnick, Katherine E, Nicholson, George, Manolopoulos, Konstantinos N, McQuaid, Siobhán E, Valet, Philippe, Frayn, Keith N, Denton, Nathan, Min, Josine L, Zondervan, Krina T, Fleckner, Jan, McCarthy, Mark I, Holmes, Chris C, Karpe, Fredrik

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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants von Pasquali, Lorenzo, Gaulton, Kyle J, Rodríguez-Seguí, Santiago A, Mularoni, Loris, Miguel-Escalada, Irene, Akerman, İldem, Tena, Juan J, Morán, Ignasi, Gómez-Marín, Carlos, van de Bunt, Martijn, Ponsa-Cobas, Joan, Castro, Natalia, Nammo, Takao, Cebola, Inês, García-Hurtado, Javier, Maestro, Miguel Angel, Pattou, François, Piemonti, Lorenzo, Berney, Thierry, Gloyn, Anna L, Ravassard, Philippe, Skarmeta, José Luis Gómez, Müller, Ferenc, McCarthy, Mark I, Ferrer, Jorge

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Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people von Finer, Sarah, Martin, Hilary C, Khan, Ahsan, Hunt, Karen A, MacLaughlin, Beverley, Ahmed, Zaheer, Ashcroft, Richard, Durham, Ceri, MacArthur, Daniel G, McCarthy, Mark I, Robson, John, Trivedi, Bhavi, Griffiths, Chris, Wright, John, Trembath, Richard C, van Heel, David A

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