Abstract 4123: ORIC-101 overcomes glucocorticoid receptor-mediated chemoresistance in pancreatic cancer models von Sun, Jessica D., Zhou, Haiying, Kong, Wayne, Yuen, Natalie, Duong, Frank L., Barkund, Shravani, Pankov, Aleksandr, McWeeney, Dan, Ye, Qiuping, Kabbarah, Omar, Friedman, Lori S., Daemen, Anneleen, Junttila, Melissa

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Abstract A133: Development of murine models to evaluate the impact of glucocorticoid receptor (GR) inhibition on chemotherapy response von Jahchan, Nadine, Zhou, Haiying, Stice, James, Kong, Wayne, McWeeney, Dan, Sun, Daqing, Rew, Yosup, Du, Xiaohui, Zhu, Liusheng, Ye, Qiuping, Jackson, Erica L., Fantin, Valeria

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Abstract 4172: Activation of AR signaling by mifepristone enhances prostate cancer growth and impairs enzalutamide response von Zhou, Haiying, Jachan, Nadine, Singh, Mallika, Tran, Chris, McWeeney, Dan, Balbas, Minna, Schenkein, Emily, Zovorotinskaya, Tatiana, Jackson, Erica L., Medina, Julio, Sun, Daqing, Rew, Yosup, Du, Xiaohui, Eksterowicz, John, Yan, Xuelei, Zhu, Liusheng, Ye, Qiuping, Fantin, Valeria

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Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms von Zhang, Haijiao, Savage, Samantha, Schultz, Anna Reister, Bottomly, Daniel, White, Libbey, Segerdell, Erik, Wilmot, Beth, McWeeney, Shannon K., Eide, Christopher A., Nechiporuk, Tamilla, Carlos, Amy, Henson, Rachel, Lin, Chenwei, Searles, Robert, Ho, Hoang, Lam, Yee Ling, Sweat, Richard, Follit, Courtney, Jain, Vinay, Lind, Evan, Borthakur, Gautam, Garcia-Manero, Guillermo, Ravandi, Farhad, Kantarjian, Hagop M., Cortes, Jorge, Collins, Robert, Buelow, Daelynn R., Baker, Sharyn D., Druker, Brian J., Tyner, Jeffrey W.

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Functional genomic landscape of acute myeloid leukaemia von Tyner, Jeffrey W., Tognon, Cristina E., Bottomly, Daniel, Wilmot, Beth, Kurtz, Stephen E., Savage, Samantha L., Long, Nicola, Schultz, Anna Reister, Traer, Elie, Abel, Melissa, Agarwal, Anupriya, Blucher, Aurora, Borate, Uma, Bryant, Jade, Burke, Russell, Carlos, Amy, Carpenter, Richie, Carroll, Joseph, Chang, Bill H., Coblentz, Cody, d’Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T., Degnin, Michie, Devine, Deirdre, Dibb, James, Edwards, David K., Eide, Christopher A., English, Isabel, Glover, Jason, Henson, Rachel, Ho, Hibery, Jemal, Abdusebur, Johnson, Kara, Johnson, Ryan, Junio, Brian, Kaempf, Andy, Leonard, Jessica, Lin, Chenwei, Liu, Selina Qiuying, Lo, Pierrette, Loriaux, Marc M., Luty, Samuel, Macey, Tara, MacManiman, Jason, Martinez, Jacqueline, Mori, Motomi, Nelson, Dylan, Nichols, Ceilidh, Peters, Jill, Ramsdill, Justin, Rofelty, Angela, Schuff, Robert, Searles, Robert, Segerdell, Erik, Smith, Rebecca L., Spurgeon, Stephen E., Sweeney, Tyler, Thapa, Aashis, Visser, Corinne, Wagner, Jake, Watanabe-Smith, Kevin, Werth, Kristen, Wolf, Joelle, White, Libbey, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R., Collins, Robert H., Connolly, Denise C., Deininger, Michael W., Drusbosky, Leylah, Hourigan, Christopher S., Jordan, Craig T., Kropf, Patricia, Lin, Tara L., Martinez, Micaela E., Medeiros, Bruno C., Pallapati, Rachel R., Pollyea, Daniel A., Swords, Ronan T., Watts, Justin M., Weir, Scott J., Wiest, David L., Winters, Ryan M., McWeeney, Shannon K., Druker, Brian J.

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Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations von Iancu, Ovidiu D, Colville, Alexandre, Oberbeck, Denesa, Darakjian, Priscila, McWeeney, Shannon K, Hitzemann, Robert

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Limited Clinical Utility of a Genetic Risk Score for the Prediction of Fracture Risk in Elderly Subjects von Eriksson, Joel, Evans, Daniel S, Nielson, Carrie M, Shen, Jian, Srikanth, Priya, Hochberg, Marc, McWeeney, Shannon, Cawthon, Peggy M, Wilmot, Beth, Zmuda, Joseph, Tranah, Greg, Mirel, Daniel B, Challa, Sashi, Mooney, Michael, Crenshaw, Andrew, Karlsson, Magnus, Mellström, Dan, Vandenput, Liesbeth, Orwoll, Eric, Ohlsson, Claes

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The Aryl Hydrocarbon Receptor Defines a Unique Genomic and Immune Signature in AML Characterized By Monocytic Differentiation, Venetoclax Resistance and Is Targetable By Ahr Antago... von Saultz, Jennifer N., Bottomly, Daniel, Burns, Faith, Byrd, Kaelan, Kosaka, Yoko, McWeeney, Shannon K., Kurtz, Stephen E., Fan, Guang, Kaempf, Andy, McGovern, Karen, Wang, Lei, Sanchez-Martin, Marta, Kaufman, Dan S, Lind, Evan F., Tyner, Jeffrey W.

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Selection for Drinking in the Dark Alters Brain Gene Coexpression Networks von Iancu, Ovidiu D., Oberbeck, Denesa, Darakjian, Priscila, Metten, Pamela, McWeeney, Shannon, Crabbe, John C., Hitzemann, Robert

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Gender‐Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs von Iancu, Ovidiu Dan, Colville, Alex M., Wilmot, Beth, Searles, Robert, Darakjian, Priscila, Zheng, Christina, McWeeney, Shannon, Kawane, Sunita, Crabbe, John C., Metten, Pamela, Oberbeck, Denesa, Hitzemann, Robert

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Abstract 791: CG'806, a first-in-class pan-FLT3/pan-BTK inhibitor, demonstrates superiority to other FLT3 and BTK inhibitors against primary patient samples von Kurtz, Stephen E., Watanabe-Smith, Kevin, Bottomly, Dan, Wilmot, Beth, Mcweeney, Shannon, Local, Andrea, Zhang, Hongying, Howell, Stephen, Rice, William, Druker, Brian J., Tyner, Jeffrey W.

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Gender‐Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNA s von Iancu, Ovidiu Dan, Colville, Alex M., Wilmot, Beth, Searles, Robert, Darakjian, Priscila, Zheng, Christina, McWeeney, Shannon, Kawane, Sunita, Crabbe, John C., Metten, Pamela, Oberbeck, Denesa, Hitzemann, Robert

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Gender Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Non-Coding RNAs von Iancu, Ovidiu Dan, Colville, Alex, Wilmot, Beth, Searles, Robert, Darakjian, Priscila, Zheng, Christina, McWeeney, Shannon, Kawane, Sunita, Crabbe, John C., Metten, Pamela, Oberbeck, Denesa, Hitzemann, Robert

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Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma von Johnson, Douglas B, Atkins, Michael B, Hennessy, Cassandra, Wise-Draper, Trisha, Heilman, Hannah, Awosika, Joy, Bakouny, Ziad, Labaki, Chris, Saliby, Renee Maria, Hwang, Clara, Singh, Sunny R K, Balanchivadze, Nino, Friese, Christopher R, Fecher, Leslie A, Yoon, James J, Hayes-Lattin, Brandon, Bilen, Mehmet A, Castellano, Cecilia A, Lyman, Gary H, Tachiki, Lisa, Shah, Sumit A, Glover, Michael J, Flora, Daniel B, Wulff-Burchfield, Elizabeth, Kasi, Anup, Abbasi, Saqib H, Farmakiotis, Dimitrios, Viera, Kendra, Klein, Elizabeth J, Weissman, Lisa B, Jani, Chinmay, Puc, Matthew, Fahey, Catherine C, Reuben, Daniel Y, Mishra, Sanjay, Beeghly-Fadiel, Alicia, French, Benjamin, Warner, Jeremy L

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Abstract 3599: Novel and established acute myeloid leukemia (AML) subsets correlate with ex vivo sensitivity to BCL-2 and PI3K inhibition von Sumiyoshi, Teiko, Bolen, Chris, Tyner, Jeff, Kurtz, Steve, Borate, Uma, McWeeney, Shannon, Wilmot, Beth, Bottomly, Dan, Segerdell, Erik, Dail, Monique, Wilson, Timothy R., Hong, Wan-Jen, Venstrom, Jeffrey M.

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Reporting guidelines for human microbiome research: the STORMS checklist von Mirzayi, Chloe, Renson, Audrey, Zohra, Fatima, Elsafoury, Shaimaa, Geistlinger, Ludwig, Kasselman, Lora J, Eckenrode, Kelly, van de Wijgert, Janneke, Loughman, Amy, Marques, Francine Z, MacIntyre, David A, Arumugam, Manimozhiyan, Azhar, Rimsha, Beghini, Francesco, Bergstrom, Kirk, Bhatt, Ami, Bisanz, Jordan E, Braun, Jonathan, Bravo, Hector Corrada, Buck, Gregory A, Bushman, Frederic, Casero, David, Clarke, Gerard, Carmen Collado, Maria, Cotter, Paul D, Cryan, John F, Demmer, Ryan T, Devkota, Suzanne, Elinav, Eran, Escobar, Juan S, Fettweis, Jennifer, Finn, Robert D, Fodor, Anthony A, Forslund, Sofia, Franke, Andre, Furlanello, Cesare, Gilbert, Jack, Grice, Elizabeth, Haibe-Kains, Benjamin, Handley, Scott, Herd, Pamela, Holmes, Susan, Jacobs, Jonathan P, Karstens, Lisa, Knight, Rob, Knights, Dan, Koren, Omry, Kwon, Douglas S, Langille, Morgan, Lindsay, Brianna, McGovern, Dermot, McHardy, Alice C, McWeeney, Shannon, Mueller, Noel T, Nezi, Luigi, Olm, Matthew, Palm, Noah, Pasolli, Edoardo, Raes, Jeroen, Redinbo, Matthew R, Ruhlemann, Malte, Sartor, R. Balfour, Schloss, Patrick D, Schriml, Lynn, Segal, Eran, Shardell, Michelle, Sharpton, Thomas, Smirnova, Ekaterina, Sokol, Harry, Sonnenburg, Justin L, Srinivasan, Sujatha, Thingholm, Louise B, Turnbaugh, Peter J, Upadhyay, Vaibhav, Walls, Ramona L, Wilmes, Paul, Yamada, Takuji, Zeller, Georg, Zhang, Mingyu, Zhao, Ni, Zhao, Liping, Bao, Wenjun, Culhane, Aedin, Devanarayan, Viswanath, Dopazo, Joaquin, Fan, Xiaohui, Fischer, Matthias, Jones, Wendell, Kusko, Rebecca, Mason, Christopher E, Mercer, Tim R, Sansone, Susanna-Assunta, Scherer, Andreas, Shi, Leming, Thakkar, Shraddha, Tong, Weida, Wolfinger, Russ, Hunter, Christopher, Segata, Nicola, Huttenhower, Curtis

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Dual-Trait Selection for Ethanol Consumption and Withdrawal: Genetic and Transcriptional Network Effects von Metten, Pamela, Iancu, Ovidiu D., Spence, Stephanie E., Walter, Nicole A. R., Oberbeck, Denesa, Harrington, Christina A., Colville, Alexandre, McWeeney, Shannon, Phillips, Tamara J., Buck, Kari J., Crabbe, John C., Belknap, John K., Hitzemann, Robert J.

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Detection of expression quantitative trait Loci in complex mouse crosses: impact and alleviation of data quality and complex population substructure von Iancu, Ovidiu D, Darakjian, Priscila, Kawane, Sunita, Bottomly, Daniel, Hitzemann, Robert, McWeeney, Shannon

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