Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins von Wang, Yunzhang, Karlsson, Robert, Lampa, Erik, Zhang, Qian, Hedman, Åsa K., Almgren, Malin, Almqvist, Catarina, McRae, Allan F., Marioni, Riccardo E., Ingelsson, Erik, Visscher, Peter M., Deary, Ian J., Lind, Lars, Morris, Tiffany, Beck, Stephan, Pedersen, Nancy L., Hägg, Sara

Volltext

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies von Hedman, Åsa K, Mendelson, Michael M, Marioni, Riccardo E, Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R, Zhi, Degui, Sandling, Johanna K, Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Tianxiao, McRae, Allan F, Demissie, Serkalem, Shah, Sonia, Starr, John M, Cupples, L Adrienne, Deloukas, Panos, Spector, Timothy D, Sundström, Johan, Krauss, Ronald M, Arnett, Donna K, Deary, Ian J, Lind, Lars, Levy, Daniel, Ingelsson, Erik

Volltext

Geographical structure and differential natural selection among North European populations von McEvoy, Brian P, Montgomery, Grant W, McRae, Allan F, Ripatti, Samuli, Perola, Markus, Spector, Tim D, Cherkas, Lynn, Ahmadi, Kourosh R, Boomsma, Dorret, Willemsen, Gonneke, Hottenga, Jouke J, Pedersen, Nancy L, Magnusson, Patrik K E, Kyvik, Kirsten Ohm, Christensen, Kaare, Kaprio, Jaakko, Heikkilä, Kauko, Palotie, Aarno, Widen, Elisabeth, Muilu, Juha, Syvänen, Ann-Christine, Liljedahl, Ulrika, Hardiman, Orla, Cronin, Simon, Peltonen, Leena, Martin, Nicholas G, Visscher, Peter M

Volltext

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood von Qi, T, Wu, Y, Zeng, J, Zhang, F, Xue, A, Jiang, L, Zhu, Z, Kemper, K, Yengo, L, Zheng, Z, Marioni, RE, Montgomery, GW, Deary, IJ, Wray, NR, Visscher, PM, McRae, AF, Yang, J

Volltext

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders von Borbye-Lorenzen, Nis, Zhu, Zhihong, Agerbo, Esben, Albiñana, Clara, Benros, Michael E., Bian, Beilei, Børglum, Anders D., Bulik, Cynthia M., Debost, Jean-Christophe Philippe Goldtsche, Grove, Jakob, Hougaard, David M., McRae, Allan F., Mors, Ole, Mortensen, Preben Bo, Musliner, Katherine L., Nordentoft, Merete, Petersen, Liselotte V., Privé, Florian, Sidorenko, Julia, Skogstrand, Kristin, Werge, Thomas, Wray, Naomi R., Vilhjálmsson, Bjarni J., McGrath, John J.

Volltext

The genetic and phenotypic correlates of neonatal Complement Component 4 protein concentration with a focus on psychiatric and autoimmune disorders von Borbye-Lorenzen, N, Zhu, ZH, Agerbo, E, Albinana, C, Benros, ME, Bian, BL, Borglum, A, Bulik, CM, Debost, JCPG, Grove, J, Hougaard, DM, McRae, AF, Mors, O, Mortensen, PB, Musliner, K, Nordentoft, M, Petersen, LV, Prive, F, Sidorenko, J, Skogstrand, K, Werge, T, Wray, NR, Vilhjalmsson, B, McGrath, JJ

Volltext

Linkage Disequilibrium in Domestic Sheep von McRae, A. F, McEwan, J. C, Dodds, K. G, Wilson, T, Crawford, A. M, Slate, J

Volltext

An epigenome-wide association study meta-analysis of educational attainment von Karlsson Linnér, R, Marioni, RE, Rietveld, CA, Simpkin, AJ, Davies, NM, Watanabe, K, Armstrong, NJ, Auro, K, Baumbach, C, Bonder, MJ, Buchwald, J, Fiorito, G, Ismail, K, Iurato, S, Joensuu, A, Karell, P, Kasela, S, Lahti, J, McRae, AF, Mandaviya, PR, Seppälä, I, Wang, Y, Baglietto, L, Binder, EB, Harris, SE, Hodge, AM, Horvath, S, Hurme, M, Johannesson, M, Latvala, A, Mather, KA, Medland, SE, Metspalu, A, Milani, L, Milne, RL, Pattie, A, Pedersen, NL, Peters, A, Polidoro, S, Räikkönen, K, Severi, G, Starr, JM, Stolk, L, Waldenberger, M, BIOS Consortium, Eriksson, JG, Esko, T, Franke, L, Gieger, C, Giles, GG, Hägg, S, Jousilahti, P, Kaprio, J, Kähönen, M, Lehtimäki, T, Martin, NG, Van Meurs, JBC, Ollikainen, M, Perola, M, Posthuma, D, Raitakari, OT, Sachdev, PS, Taskesen, E, Uitterlinden, AG, Vineis, P, Wijmenga, C, Wright, MJ, Relton, C, Davey Smith, G, Deary, IJ, Koellinger, PD, Benjamin, DJ

Volltext

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases von Ligthart, S, Marzi, C, Aslibekyan, S, Mendelson, MM, Conneely, KN, Tanaka, T, Colicino, E, Waite, LL, Joehanes, R, Guan, W, Brody, JA, Elks, C, Marioni, R, Jhun, MA, Agha, G, Bressler, J, Ward-Caviness, CK, Chen, BH, Huan, T, Bakulski, K, Salfati, EL, Wahl, S, Schramm, K, Sha, J, Hernandez, DG, Just, AC, Smith, JA, Sotoodehnia, N, Pilling, LC, Pankow, JS, Tsao, PS, Liu, C, Zhao, W, Guarrera, S, Michopoulos, VJ, Smith, AK, Peters, MJ, Melzer, D, Vokonas, P, Fornage, M, Prokisch, H, Bis, JC, Chu, AY, Herder, C, Grallert, H, Yao, C, Shah, S, McRae, AF, Lin, H, Horvath, S, Fallin, D, Hofman, A, Wareham, NJ, Wiggins, KL, Feinberg, AP, Starr, JM, Visscher, PM, Murabito, JM, Kardia, SLR, Absher, DM, Binder, EB, Singleton, AB, Bandinelli, S, Peters, A, Waldenberger, M, Matullo, G, Schwartz, JD, Demerath, EW, Uitterlinden, AG, Van Meurs, JBJ, Franco, OH, Chen, Y-DI, Levy, D, Turner, ST, Deary, IJ, Ressler, KJ, Dupuis, J, Ferrucci, L, Ong, KK, Assimes, TL, Boerwinkle, E, Koenig, W, Arnett, DK, Baccarelli, AA, Benjamin, EJ, Dehghan, A

Volltext

Examination of a region showing linkage map discrepancies across sheep breeds von McRae, Allan F, Beraldi, Dario

Volltext

Modeling Linkage Disequilibrium in Natural Populations: The Example of the Soay Sheep Population of St. Kilda, Scotland von McRae, Allan F, Pemberton, Josephine M, Visscher, Peter M

Volltext

Bone density in sheep: genetic variation and quantitative trait loci localisation von Campbell, A.W, Bain, W.E, McRae, A.F, Broad, T.E, Johnstone, P.D, Dodds, K.G, Veenvliet, B.A, Greer, G.J, Glass, B.C, Beattie, A.E, Jopson, N.B, McEwan, J.C

Volltext

Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers von Boen, R, Kaufmann, T, van der Meer, D, Frei, O, Agartz, I, Ames, D, Andersson, M, Armstrong, NJ, Artiges, E, Atkins, JR, Bauer, J, Boomsma, DI, Brodaty, H, Brosch, K, Buckner, RL, Cairns, MJ, Calhoun, V, Caspers, S, Cichon, S, Corvin, AP, Crespo-Facorro, B, Dannlowski, U, David, FS, de Geus, EJC, de Zubicaray, GI, Desrivières, S, Doherty, JL, Donohoe, G, Ehrlich, S, Eising, E, Espeseth, T, Fisher, SE, Forstner, AJ, Fortaner-Uyà, L, Frouin, V, Fukunaga, M, Ge, T, Glahn, DC, Goltermann, J, Grabe, HJ, Green, MJ, Groenewold, NA, Grotegerd, D, Grøntvedt, GR, Hahn, T, Hashimoto, R, Hehir-Kwa, JY, Henskens, FA, Holmes, AJ, Håberg, AK, Haavik, J, Jacquemont, S, Jansen, A, Jockwitz, C, Jönsson, EG, Kikuchi, M, Kircher, T, Kumar, K, Le Hellard, S, Leu, C, Linden, DE, Liu, J, Loughnan, R, Mather, KA, McMahon, KL, McRae, AF, Medland, SE, Meinert, S, Moreau, CA, Morris, DW, Mowry, BJ, Mühleisen, TW, Nenadić, I, Nöthen, MM, Nyberg, L, Ophoff, RA, Owen, MJ, Pantelis, C, Paus, T, Pausova, Z, Persson, K, Quidé, Y, Marques, TR, Sachdev, PS, Sando, SB, Schall, U, Scott, RJ, Selbæk, G, Shumskaya, E, Silva, AI, Sisodiya, SM, Stein, F, Stein, DJ, Straube, B, Streit, F, Teumer, A, Teutenberg, L, Quide, Yann, Wen, Wei, Thalamuthu, Anbu

Volltext bestellen

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1 von Restuadi, R, Steyn, FJ, Kabashi, E, Ngo, ST, Cheng, F-F, Nabais, MF, Thompson, MJ, Qi, T, Wu, Y, Henders, AK, Wallace, L, Bye, CR, Turner, BJ, Ziser, L, Mathers, S, McCombe, PA, Needham, M, Schultz, D, Kiernan, MC, van Rheenen, W, van den Berg, LH, Veldink, JH, Ophoff, R, Gusev, A, Zaitlen, N, McRae, AF, Henderson, RD, Wray, NR, Giacomotto, J, Garton, FC

Volltext bestellen

Identical twins carry a persistent epigenetic signature of early genome programming von Van Dongen, J, Gordon, SD, McRae, AF, Odintsova, VV, Mbarek, H, Breeze, CE, Sugden, K, Lundgren, S, Castillo-Fernandez, JE, Hannon, E, Moffitt, TE, Hagenbeek, FA, Van Beijsterveldt, CEM, Jan Hottenga, J, Tsai, P-C, van Dongen, J, Hottenga, J-J, Min, JL, Hemani, G, Ehli, EA, Paul, F, Stern, CD, Heijmans, BT, Slagboom, PE, Daxinger, L, van der Maarel, SM, De Geus, EJC, Willemsen, G, Montgomery, GW, Reversade, B, Ollikainen, M, Kaprio, J, Spector, TD, Bell, JT, Mill, J, Caspi, A, Martin, NG, Boomsma, DI

Volltext bestellen

Author Correction: Bayesian reassessment of the epigenetic architecture of complex traits von Banos, DT, McCartney, DL, Patxot, M, Anchieri, L, Battram, T, Christiansen, C, Costeira, R, Walker, RM, Morris, SW, Campbell, A, Zhang, Q, Porteous, DJ, McRae, AF, Wray, NR, Visscher, PM, Haley, CS, Evans, KL, Deary, IJ, McIntosh, AM, Hemani, G, Bell, JT, Marioni, RE, Robinson, MR

Volltext bestellen

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology von Bakker, MK, Westra, H-J, Deelen, P, Dolzhenko, E, Gawor, K, Tazelaar, GHP, Doherty, M, Al Khleifat, A, Shatunov, A, Smith, BN, Shaw, PJ, Sendtner, M, Fogh, I, Lauria, G, Sproviero, D, D’Alfonso, S, Sorarù, G, Siciliano, G, Padovani, A, Moglia, C, Brunetti, M, Lerner, Y, Zabari, M, Gotkine, M, Millecamps, S, Meininger, V, Rojas-García, R, Dion, PA, Ross, JP, Durr, A, Payan, CAM, Wood, NW, Franke, A, Ripke, S, Whiteman, DC, Gerardi, F, Cotelli, MS, Rinaldi, F, Guaita, MC, Ceroni, M, Ferrarese, C, Delodovici, ML, Vasta, R, Bombaci, A, Casale, F, Fuda, G, Salamone, P, Iazzolino, B, Peotta, L, Palumbo, F, Gallone, S, Sbaiz, L, Mauro, A, De Marchi, F, Gionco, M, Pignatta, P, De Mattei, M, Papurello, DM, Gusmaroli, G, Comi, C, Ruiz, L, Di Vito, N, Meineri, P, Ghiglione, P, Dotta, M, Di Sapio, A, Tiloca, C, Gagliardi, S, Ferlini, A, Mundi, C, Zarrelli, M, Cauchi, RJ, Wiedau-Pazos, M, Lomen-Hoerth, C, van Deerlin, VM, Jörk, A, Graff, C, Fominykh, V, Ataulina, A, Koritnik, B, Zidar, J, Glavač, D, Drory, V, McCombe, PA, Ngo, ST, Pamphlett, R, Williams, KL, Wallace, L, Brown, RH, Andersen, PM, van Es, MA, Fan, D, Garton, FC, Davey Smith, G, Mill, J, Hardiman, O, Wray, NR, Franke, L, van den Berg, LH, Veldink, JH

Volltext bestellen

Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis von Nabais, MF, Lin, T, Benyamin, B, Williams, KL, Garton, FC, Vinkhuyzen, AAE, Zhang, F, Vallerga, CL, Restuadi, R, Freydenzon, A, Zwamborn, RAJ, Hop, PJ, Robinson, MR, Gratten, J, Visscher, PM, Hannon, E, Mill, J, Brown, MA, Laing, NG, Mather, KA, Sachdev, PS, Ngo, ST, Steyn, FJ, Wallace, L, Henders, AK, Needham, M, Veldink, JH, Mathers, S, Nicholson, G, Rowe, DB, Henderson, RD, McCombe, PA, Pamphlett, R, Yang, J, Blair, IP, McRae, AF, Wray, NR

Volltext bestellen

Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs von Sønderby, IE, Ching, CRK, Thomopoulos, SI, van der Meer, D, Sun, D, Villalon-Reina, JE, Agartz, I, Amunts, K, Arango, C, Armstrong, NJ, Ayesa-Arriola, R, Bakker, G, Bassett, AS, Boomsma, DI, Bülow, R, Butcher, NJ, Calhoun, VD, Caspers, S, Chow, EWC, Cichon, S, Ciufolini, S, Craig, MC, Crespo-Facorro, B, Cunningham, AC, Dale, AM, Dazzan, P, de Zubicaray, GI, Doherty, JL, Donohoe, G, Draganski, B, Durdle, CA, Ehrlich, S, Emanuel, BS, Espeseth, T, Fisher, SE, Ge, T, Glahn, DC, Grabe, HJ, Gur, RE, Gutman, BA, Håberg, AK, Hansen, LA, Hashimoto, R, Hibar, DP, Holmes, AJ, Hottenga, J-J, Hulshoff Pol, HE, Jalbrzikowski, M, Knowles, EEM, Kushan, L, Linden, DEJ, Liu, J, Lundervold, AJ, Martin-Brevet, S, Martínez, K, Mather, KA, Mathias, SR, McDonald-McGinn, DM, McRae, AF, Medland, SE, Moberget, T, Modenato, C, Monereo Sánchez, J, Moreau, CA, Mühleisen, TW, Paus, T, Pausova, Z, Prieto, C, Ragothaman, A, Reis Marques, T, Repetto, GM, Reymond, A, Roalf, DR, Rodriguez-Herreros, B, Rucker, JJ, Sachdev, PS, Schmitt, JE, Schofield, PR, Silva, AI, Stefansson, H, Stein, DJ, Tamnes, CK, Tordesillas-Gutiérrez, D, Ulfarsson, MO, Vajdi, A, van 't Ent, D, van den Bree, MBM, Vassos, E, Vázquez-Bourgon, J, Vila-Rodriguez, F, Walters, GB, Wen, W, Westlye, LT, Zackai, EH, Stefánsson, K, Thompson, PM, Bearden, CE, Andreassen, OA, ENIGMA-CNV Working Group, ENIGMA 22q11.2 Deletion Syndrome Working Group

Volltext bestellen

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology von van der Spek, RAA, Bakker, MK, de Klein, N, Westra, H-J, Deelen, P, Dolzhenko, E, Gawor, K, Westeneng, H-J, Tazelaar, GHP, van Eijk, KR, Kooyman, M, Doherty, M, Al Khleifat, A, Shatunov, A, Ticozzi, N, Cooper-Knock, J, Smith, BN, Shaw, PJ, Hardy, J, Sendtner, M, van der Kooi, AJ, Fogh, I, Lauria, G, Sproviero, D, Sorarù, G, Siciliano, G, Padovani, A, Moglia, C, Brunetti, M, Grassano, M, Logroscino, G, Nefussy, B, Nordin, A, Lerner, Y, Zabari, M, Gotkine, M, Millecamps, S, Meininger, V, Mora Pardina, JS, Assialioui, A, Rojas-García, R, Dion, PA, Ross, JP, Freischmidt, A, Bensimon, G, Durr, A, Payan, CAM, Wood, NW, Tittmann, L, Lieb, W, Franke, A, Ripke, S, Whiteman, DC, Hofman, A, PARALS Consortium, SLAP Consortium, Traynor, BJ, Singleton, AB, Mitne Neto, M, Cauchi, RJ, Ophoff, RA, Wiedau-Pazos, M, Grosskreutz, J, Roediger, A, Gaur, N, Jörk, A, Witte, OW, Steinbach, R, Ataulina, A, Rogelj, B, Zidar, J, Glavač, D, Stević, Z, Drory, V, Povedano, M, Henderson, RD, Mathers, S, McCombe, PA, Pamphlett, R, Mather, KA, Henders, AK, Wallace, L, de Carvalho, M, Petri, S, Breen, G, Glass, JD, Shaw, CE, Andersen, PM, Groen, EJN, Pasterkamp, RJ, Fan, D, Garton, FC, McRae, AF, Davey Smith, G, Eberle, MA, Hardiman, O, Kenna, KP, Wray, NR, Runz, H, Veldink, JH

Volltext bestellen