An Inhibitor of the Protease Blocks Maturation of Human and Simian Immunodeficiency Viruses and Spread of Infection von Ashorn, Per, McQuade, Thomas J., Thaisrivongs, Suvit, Tomasselli, Alfredo G., Tarpley, W. Gary, Moss, Bernard

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A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle Maturation von McQuade, T. J., Tomasselli, A. G., Liu, L., Karacostas, V., Moss, B., Sawyer, T. K., Heinrikson, R. L., Tarpley, W. G.

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Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effect... von Thaisrivongs, Suvit, Tomasselli, Alfredo G, Moon, Joseph B, Hui, John, McQuade, Thomas J, Turner, Steve R, Strohbach, Joseph W, Howe, W. Jeffrey, Tarpley, W. Gary, Heinrikson, Robert L

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Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors von Islam, I, Ng, K. Y, Chong, K. T, McQuade, T. J, Hui, J. O, Wilkinson, K. F, Rush, B. D, Ruwart, M. J, Borchardt, R. T, Fisher, J. F

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Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transit... von Thaisrivongs, Suvit, Turner, Steve R, Strohbach, Joseph W, TenBrink, Ruth E, Tarpley, W. Gary, McQuade, Thomas J, Heinrikson, Robert L, Tomasselli, Alfredo G, Hui, John O, Howe, W. Jeffrey

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A rapid solution immunoassay to quantify binding of the human immunodeficiency virus envelope glycoprotein to soluble CD4 von McQuade, T.J., Pitts, T.W., Tarpley, W.G.

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Denaturation/refolding of purified recombinant HIV reverse transcriptase yields monomeric enzyme with high enzymatic activity von DEIBEL, M. R, MCQUADE, T. J, BRUNNER, D. P, TARPLEY, W. G

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An ultrasensitive human immunodeficiency virus type 1 protease radioimmuno rate assay with a potential for monitoring blood levels of protease inhibitors in acquired immunodeficien... von Evans, David B., Vosters, Anne F., McQuade, Thomas J., Sharma, Satish K.

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Soluble CD4-PE40 is cytotoxic for a transfected mammalian cell line stably expressing the envelope protein of human immunodeficiency virus (HIV-1), and cytotoxicity is variably inh... von PITTS, T. W, BOHANON, M. J, LEACH, M. F, MCQUADE, T. J, MARSCHKE, C. K, MERRITT, J. A, WIERENGA, W, NICHOLAS, J. A

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Discovery and optimization of nonpeptide HIV-1 protease inhibitors von Tummino, Peter J., Vara Prasad, J.V.N., Ferguson, Donna, Nouhan, Carolyn, Graham, Neil, Domagala, John M., Ellsworth, Edmund, Gajda, Christopher, Hagen, Susan E., Lunney, Elizabeth A., Para, Kimberly S., Tait, Bradley D., Pavlovsky, Alexander, Erickson, John W., Gracheck, Stephen, McQuade, Thomas J., Hupe, Donald J.

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Nonpeptidic potent HIV-1 protease inhibitors : (4-hydroxy-6-phenyl-2-oxo-2H-pyran-3-yl)thiomethanes that span P1-P2' subsites in a unique mode of active site binding von VARA PRASAD, J. V. N, PARA, K. S, GRACHECK, S. J, BHAT, T. N, BEISHAN LIU, BALDWIN, E. T, ERICKSON, J. W, SAWYER, T. K, TUMMINO, P. J, FERGUSON, D, MCQUADE, T. J, LUNNEY, E. A, RAPUNDALO, S. T, BATLEY, B. L, HINGORANI, G, DOMAGALA, J. M

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Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties von Sawyer, T.K., Fisher, J.F., Hester, J.B., Smith, C.W., Tomasselli, A.G., Tarpley, W.G., Burton, P.S., Hui, J.O., McQuade, T.J., Conradi, R.A., Bradford, V.S., Liu, L., Kinner, J.H., Tustin, J., Alexander, D.L., Harrison, A.W., Emmert, D.E., Staples, D.J., Maggiora, L.L., Zhang, Y.Z., Poorman, R.A., Dunna, B.M., Rao, C., Scarborough, P.E., Lowther, W.T., Craik, C., DeCamp, D., Moon, J., Howe, W.J., Heinrikson, R.L.

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Nonpeptidic HIV protease inhibitors: 4-hydroxy-pyran-2-one inhibitors with functional tethers to P1 phenyl ring to reach S3 pocket of the enzyme von Vara Prasad, J, Tummino, P J, Ferguson, D, Saunders, J, Vander Roest, S, McQuade, T J, Heldsinger, A, Reyner, E L, Stewart, B H, Guttendorf, R J, Para, K S, Lunney, E A, Gracheck, S J, Domagala, J M

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Nonpeptidic potent HIV-1 protease inhibitors: (4-hydroxy-6-phenyl-2-oxo-2H-pyran-3-yl)thiomethanes that span P sub(1)-P sub(2)' subsites in a unique mode of active site binding von Vara Prasad, JVN, Para, K S, Tummino, P J, Ferguson, D, McQuade, T J, Lunney, E A, Rapundalo, ST, Batley, B L, Hingorani, G

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Purification of an active monomeric recombinant HIV-1 trans-activator von Waszak, Gregory A., Hasler, Jim M., McQuade, Thomas J., Tarpley, W. Gary, Deibel, Martin R.

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A synthesis HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation von MCQUADE, T. J, TOMASSELLI, A. G, LIU, L, KARACOSTAS, V, MOSS, B, SAWYER, T. K, HEINRIKSON, R. L, TARPLEY, W. G

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Molecular orbital calculations on transition element compounds: II. CNDO type studies of permanganate and chromate von Brown, R. D., James, B. H., McQuade, T. J. V., O'Dwyer, M. F.

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Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease von Torres, Vicente E, Chapman, Arlene B, Devuyst, Olivier, Gansevoort, Ron T, Perrone, Ronald D, Koch, Gary, Ouyang, John, McQuade, Robert D, Blais, Jaime D, Czerwiec, Frank S, Sergeyeva, Olga

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Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab von Menzies, A.M., Johnson, D.B., Ramanujam, S., Atkinson, V.G., Wong, A.N.M., Park, J.J., McQuade, J.L., Shoushtari, A.N., Tsai, K.K., Eroglu, Z., Klein, O., Hassel, J.C., Sosman, J.A., Guminski, A., Sullivan, R.J., Ribas, A., Carlino, M.S., Davies, M.A., Sandhu, S.K., Long, G.V.

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How Do Foreclosures Exacerbate Housing Downturns? von GUREN, ADAM M., MCQUADE, TIMOTHY J.

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