Achieving Precision Death with Cell-Cycle Inhibitors that Target DNA Replication and Repair von Lin, Aimee Bence, McNeely, Samuel C, Beckmann, Richard P

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The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells von Landau, Heather J, McNeely, Samuel C, Nair, Jayasree S, Comenzo, Raymond L, Asai, Takashi, Friedman, Hillel, Jhanwar, Suresh C, Nimer, Stephen D, Schwartz, Gary K

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Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent von McNeely, Samuel C., Taylor, B. Frazier, States, J. Christopher

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A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors von Garralda, Elena, Schram, Alison M, Bedard, Philippe L, Schwartz, Gary K, Yuen, Eunice, McNeely, Samuel C, Ribeiro, Silvia, Cunningham, Jason, Wang, Yi, Urunuela, Arantxa, Xu, Xiaojian, LoRusso, Patricia

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Addition of ramucirumab or merestinib to standard first-line chemotherapy for locally advanced or metastatic biliary tract cancer: a randomised, double-blind, multicentre, phase 2... von Valle, Juan W, Vogel, Arndt, Denlinger, Crystal S, He, Aiwu Ruth, Bai, Li-Yuan, Orlova, Rashida, Van Cutsem, Eric, Adeva, Jorge, Chen, Li-Tzong, Obermannova, Radka, Ettrich, Thomas J, Chen, Jen-Shi, Wasan, Harpreet, Girvan, Allicia C, Zhang, Wei, Liu, Jiangang, Tang, Chunlao, Ebert, Philip J, Aggarwal, Amit, McNeely, Samuel C, Moser, Brian A, Oliveira, Joana M, Carlesi, Roberto, Walgren, Richard A, Oh, Do-Youn

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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib von Blosser, Wayne D, Dempsey, Jack A, McNulty, Ann M, Rao, Xi, Ebert, Philip J, Lowery, Caitlin D, Iversen, Philip W, Webster, Yue Wang, Donoho, Gregory P, Gong, Xueqian, Merzoug, Farhana F, Buchanan, Sean, Boehnke, Karsten, Yu, Chunping, You, Xin Tian, Beckmann, Richard P, Wu, Wenjuan, McNeely, Samuel C, Lin, Aimee Bence, Martinez, Ricardo

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Pirtobrutinib, a highly selective, non-covalent (reversible) BTK inhibitor in patients with B-cell malignancies: analysis of the Richter transformation subgroup from the multicentr... von Wierda, William G, Shah, Nirav N, Cheah, Chan Y, Lewis, David, Hoffmann, Marc S, Coombs, Catherine C, Lamanna, Nicole, Ma, Shuo, Jagadeesh, Deepa, Munir, Talha, Wang, Yucai, Eyre, Toby A, Rhodes, Joanna M, McKinney, Matthew, Lech-Maranda, Ewa, Tam, Constantine S, Jurczak, Wojciech, Izutsu, Koji, Alencar, Alvaro J, Patel, Manish R, Seymour, John F, Woyach, Jennifer A, Thompson, Philip A, Abada, Paolo B, Ho, Caleb, McNeely, Samuel C, Marella, Narasimha, Nguyen, Bastien, Wang, Chunxiao, Ruppert, Amy S, Nair, Binoj, Liu, Hui, Tsai, Donald E, Roeker, Lindsey E, Ghia, Paolo

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Arsenite Disrupts Mitosis and Induces Apoptosis in SV40-Transformed Human Skin Fibroblasts von States, J.Christopher, Reiners, John J., Pounds, Joel G., Kaplan, David J., Beauerle, Brian D., McNeely, Samuel C., Mathieu, Patricia, McCabe, Michael J.

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Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization von Taylor, B. Frazier, McNeely, Samuel C., Miller, Heather L., States, J. Christopher

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Suppression of p53 and p21CIP1/WAF1 Reduces Arsenite-Induced Aneuploidy von Salazar, Ana María, Miller, Heather L, McNeely, Samuel C, Sordo, Monserrat, Ostrosky-Wegman, Patricia, States, J. Christopher

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Exit from Arsenite-Induced Mitotic Arrest Is p53 Dependent von McNeely, Samuel C., Xu, Xiaogiang, Taylor, B. Frazier, Zacharias, Wolfgang, McCabe, Michael J., States, J. Christopher

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Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest von McNeely, Samuel C., Belshoff, Alex C., Taylor, B. Frazier, Fan, Teresa W-M., McCabe, Michael J., Pinhas, Allan R., States, J. Christopher

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Addition of ramucirumab or merestinib to standard first-line chemotherapy for locally advanced or metastatic biliary tract cancer: a randomised, double-blind, multicentre, phase 2... von Valle, Juan W, Vogel, Arndt, Denlinger, Crystal S, He, Aiwu Ruth, Bai, Li-Yuan, Orlova, Rashida, Van Cutsem, Eric, Adeva, Jorge, Chen, Li-Tzong, Obermannova, Radka, Ettrich, Thomas J, Chen, Jen-Shi, Wasan, Harpreet, Girvan, Allicia C, Zhang, Wei, Liu, Jiangang, Tang, Chunlao, Ebert, Philip J, Aggarwal, Amit, McNeely, Samuel C, Moser, Brian A, Oliveira, Joana M, Carlesi, Roberto, Walgren, Richard A, Oh, Do-Youn

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Abstract A108: LY2606368, a second generation Chk1 inhibitor, inhibits growth of ovarian carcinoma xenografts either as monotherapy or in combination with standard-of-care agents von McNeely, Samuel C., Burke, Teresa F., DurlandBusbice, Sara, Barnard, Darlene S., Marshall, Mark S., Bence, Aimee K., Beckmann, Richard P.

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Suppression of p53 and p21 CIP1/WAF1 Reduces Arsenite-Induced Aneuploidy von Salazar, Ana María, Miller, Heather L., McNeely, Samuel C., Sordo, Monserrat, Ostrosky-Wegman, Patricia, States, J. Christopher

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A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors von Garralda, Elena, Schram, Alison M, Bedard, Philippe L, Schwartz, Gary K, Yuen, Eunice, McNeely, Samuel C, Ribeiro, Silvia, Cunningham, Jason, Wang, Yi, Urunuela, Arantxa, Xu, Xiaojian, LoRusso, Patricia

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Arsenite Disrupts Mitosis and Induces Apoptosis in SV40-Transformed Human Skin Fibroblasts von Christopher States, J., Reiners, John J., Pounds, Joel G., Kaplan, David J., Beauerle, Brian D., McNeely, Samuel C., Mathieu, Patricia, McCabe, Michael J.

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Arsenite Disrupts Mitosis and Induces Apoptosis in SV40-Transformed Human Skin Fibroblasts: Volume 180, Number 2 (2002), pages 83–91 von Christopher States, J., Reiners, John J., Pounds, Joel G., Kaplan, David J., Beauerle, Brian D., McNeely, Samuel C., Mathieu, Patricia, McCabe, Michael J.

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Arsenite treatment delays mitotic entry, and p53 deficiency delays mitotic exit in arsenite-treated cells von McNeely, Samuel C., Xiaogiang Xu, B. Frazier Taylor, Zacharias, Wolfgang, McCabe, Michael J., J. Christopher States

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Synchronization of TR9-7 cells expressing or not expressing p53 in G phase von McNeely, Samuel C., Xiaogiang Xu, B. Frazier Taylor, Zacharias, Wolfgang, McCabe, Michael J., J. Christopher States

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