Phase II Trial of Pertuzumab and Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer That Progressed During Prior Trastuzumab Th... von BASELGA, José, GELMON, Karen A, FUMOLEAU, Pierre, GIANNI, Luca, VERMA, Shailendra, WARDLEY, Andrew, CONTE, Pierfranco, MILES, David, BIANCHI, Giulia, CORTES, Javier, MCNALLY, Virginia A, ROSS, Graham A

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Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase von McNally, Virginia A., Rajabi, Mehdi, Gbaj, Abdul, Stratford, Ian J., Edwards, Philip N., Douglas, Kenneth T., Bryce, Richard A., Jaffar, Mohammed, Freeman, Sally

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Synthesis and enzymatic evaluation of pyridinium-Substituted uracil derivatives as novel inhibitors of thymidine phosphorylase von Murray, Paul E, McNally, Virginia A, Lockyer, Stacey D, Williams, Kaye J, Stratford, Ian J, Jaffar, Mohammed, Freeman, Sally

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ChemInform Abstract: Synthesis and Enzymatic Evaluation of Pyridinium-Substituted Uracil Derivatives as Novel Inhibitors of Thymidine Phosphorylase von Murray, Paul E., McNally, Virginia A., Lockyer, Stacey D., Williams, Kaye J., Stratford, Ian J., Jaffar, Mohammed, Freeman, Sally

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5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, op... von Gianni, Luca, Prof, Pienkowski, Tadeusz, Prof, Im, Young-Hyuck, Prof, Tseng, Ling-Ming, MD, Liu, Mei-Ching, MD, Lluch, Ana, MD, Starosławska, Elżbieta, Prof, de la Haba-Rodriguez, Juan, MD, Im, Seock-Ah, Prof, Pedrini, Jose Luiz, MD, Poirier, Brigitte, MD, Morandi, Paolo, MD, Semiglazov, Vladimir, Prof, Srimuninnimit, Vichien, Prof, Bianchi, Giulia Valeria, MD, Magazzù, Domenico, PhD, McNally, Virginia, PhD, Douthwaite, Hannah, MSc, Ross, Graham, FFPM, Valagussa, Pinuccia, BS

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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAF(V600) mutation-positive melanoma (IMspire150): primary analysis of the randomised,... von Gutzmer, Ralf, Stroyakovskiy, Daniil, Gogas, Helen, Robert, Caroline, Lewis, Karl, Protsenko, Svetlana, Pereira, Rodrigo P., Eigentler, Thomas, Rutkowski, Piotr, Demidov, Lev, Manikhas, Georgy Moiseevich, Yan, Yibing, Huang, Kuan-Chieh, Uyei, Anne, McNally, Virginia, McArthur, Grant A., Ascierto, Paolo A.

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Cells Undergo Major Changes in the Quantity of Cytoplasmic Organelles after Uptake of Gold Nanoparticles with Biologically Relevant Surface Coatings von Kepsutlu, Burcu, Wycisk, Virginia, Achazi, Katharina, Kapishnikov, Sergey, Pérez-Berná, Ana Joaquina, Guttmann, Peter, Cossmer, Antje, Pereiro, Eva, Ewers, Helge, Ballauff, Matthias, Schneider, Gerd, McNally, James G

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Combination Targeted Therapy With Sorafenib and Bevacizumab Results in Enhanced Toxicity and Antitumor Activity von AZAD, Nilofer S, POSADAS, Edwin M, LIANG CAO, MCNALLY, Deborah, CHOW, Catherine, CHEN, Helen X, WRIGHT, John J, KOHN, Elise C, KWITKOWSKI, Virginia E, STEINBERG, Seth M, JAIN, Lokesh, ANNUNZIATA, Christina M, MINASIAN, Lori, SAROSY, Gisele, KOTZ, Herbert L, PREMKUMAR, Ahalya

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Evaluating the predictive value of biomarkers for efficacy outcomes in response to pertuzumab- and trastuzumab-based therapy: an exploratory analysis of the TRYPHAENA study von Schneeweiss, Andreas, Chia, Stephen, Hegg, Roberto, Tausch, Christoph, Deb, Rahul, Ratnayake, Jayantha, McNally, Virginia, Ross, Graham, Kiermaier, Astrid, Cortés, Javier

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Association of baseline systemic corticosteroid use with overall survival and time to next treatment in patients receiving immune checkpoint inhibitor therapy in real-world US onco... von Drakaki, Alexandra, Dhillon, Preet K, Wakelee, Heather, Chui, Stephen Y, Shim, Jinjoo, Kent, Matthew, Degaonkar, Viraj, Hoang, Tien, McNally, Virginia, Luhn, Patricia, Gutzmer, Ralf

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High-plasma soluble prorenin receptor is associated with vascular damage in male, but not female, mice fed a high-fat diet von Visniauskas, Bruna, Reverte, Virginia, Abshire, Caleb M, Ogola, Benard O, Rosales, Carla B, Galeas-Pena, Michelle, Sure, Venkata N, Sakamuri, Siva S V P, Harris, Nicholas R, Kilanowski-Doroh, Isabella, Mcnally, Alexandra B, Horton, Alec C, Zimmerman, Margaret, Katakam, Prasad V G, Lindsey, Sarah H, Prieto, Minolfa C

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Tumor-Infiltrating Lymphocytes in Patients Receiving Trastuzumab/Pertuzumab-Based Chemotherapy: A TRYPHAENA Substudy von Ignatiadis, Michail, Van den Eynden, Gert, Roberto, Salgado, Fornili, Marco, Bareche, Yacine, Desmedt, Christine, Rothé, Françoise, Maetens, Marion, Venet, David, Holgado, Esther, McNally, Virginia, Kiermaier, Astrid, Savage, Heidi M, Wilson, Timothy R, Cortes, Javier, Schneeweiss, Andreas, Willard-Gallo, Karen, Biganzoli, Elia, Sotiriou, Christos

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Returning integrated genomic risk and clinical recommendations: The eMERGE study von Chisholm, Rex L., Clayton, Ellen Wright, DiVietro, Alanna, Green, Richard, Harden, Maegan V., Limdi, Nita A., Rasmussen, Luke V., Schmidlen, Tara, Cimino, James J., Guiducci, Candace, Harr, Margaret, Larkin, Katie, Mooney, Sean D., Mutai, Brenda, Namjou, Bahram, Perez, Emma F., Saadatagah, Seyedmohammad, Seabolt, Lynn, Shaibi, Gabriel Q., Sharp, Richard R., Sterling, Rene, Tiwari, Hemant K., Allworth, Aimee, DiVietro, Alanna, Khera, Amit, Kontorovich, Amy, Prince, Anya, Iverson, Ayuko, Khales, Bahram Namjou, Benoit, Barbara, Satterfield, Benjamin, Devine, Beth, Grundmeier, Bob, Piening, Brian, Korf, Bruce, Hammack, Catherine, Gascoigne, Caytie, Lange, Christoph, Liu, Cong, Shimbo, Daichi, Singh, Davinder, Edwards, Digna Velez, Morales, Eduardo, Cohn, Elizabeth, Karlson, Elizabeth, DeFranco, Emily, Perez, Emma, Cash, Erin, Berner, Eta, Wang, Fei, Mentch, Frank, Wiesner, Georgia, Belbin, Gillian, Hakonarson, Hakon, Tiwari, Hemant, Thomas, Hope, Hellwege, Jacklyn, Snyder, James, Olson, Janet, Glessner, Joe, Alsip, Jorge, Kannry, Joseph, Peterson, Josh, Galasso, Julia, Starren, Justin, Mittendorf, Kate, Anderson, Katherine, Bonini, Katherine, Rasmussen-Torvik, Laura, Gomez, Lizbeth, Petukhova, Lynn, Beasley, Mark, Horike, Martha, Hamed, Marwan, Davis, Matthew, Preuss, Michael, Shi, Mingjian, Perera, Minoli, Elkind, Mitch, Saadatagah, Mohammad, Netherly, Neil, Lennon, Niall, Limdi, Nita, Robinson, Nora, Elsekaily, Omar, Kovatch, Patricia, O’Reilly, Paul, Murali, Priyanka, Sharp, Richard, Peters, Riki, Rowley, Robb, Freimuth, Robert, Green, Robert, Winter, Robert, Irvin, Ryan, Knerr, Sarah, Bland, S.T., Booth, Stuart James, Desai, Vimi, Luo, Yuan

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Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III I... von Zhou, Caicun, Srivastava, Minu K, Xu, Hao, Felip, Enriqueta, Wakelee, Heather, Altorki, Nasser, Reck, Martin, Liersch, Rüdiger, Kryzhanivska, Anna, Oizumi, Satoshi, Tanaka, Hiroshi, Hamm, John, McCune, Steven L, Bennett, Elizabeth, Gitlitz, Barbara, McNally, Virginia, Ballinger, Marcus, McCleland, Mark, Zou, Wei, Das Thakur, Meghna, Novello, Silvia

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PS1-5 IMpower010: results from Asian patients in a phase 3 study of adjuvant atezolizumab in resected stage IB-IIIA NSCLC von Kenmotsu, Hirotsugu, Zhou, Caicun, Altorki, Nasser, Felip, Enriqueta, Vallieres, Eric, Sugawara, Shunichi, Sakai, Hiroshi, Saito, Haruhiro, Tao, Min, Kawaguchi, Koji, Liu, Yunpeng, Yu, Chong-Jen, Wu, Qiong, Lin, Huang, Wu, Fan, Bennett, Elizabeth, Mcnally, Virginia, Gitlitz, Barbara, Wakelee, Heather

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Abstract 5388: Association of baseline systemic corticosteroid use with time to next treatment in patients with advanced melanoma, non-small cell lung cancer or urothelial cancer r... von Drakaki, Alexandra, Dhillon, Preet K., Wakelee, Heather, Chui, Stephen Y., Shim, Jinjoo, Kent, Matthew, Degaonkar, Viraj, Hoang, Tien, McNally, Virginia, Luhn, Patricia, Gutzmer, Ralf

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The Effects of a Low Sodium Meal Plan on Blood Pressure in Older Adults: The SOTRUE Randomized Feasibility Trial von Juraschek, Stephen P., Millar, Courtney L., Foley, Abby, Shtivelman, Misha, Cohen, Alegria, McNally, Virginia, Crevatis, Robert, Post, Stephen M., Mukamal, Kenneth J., Lipsitz, Lewis A., Cluett, Jennifer L., Davis, Roger B., Sahni, Shivani

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2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3 – Recommendations o... von Piccoli, Steven, Mehta, Devangi, Vitaliti, Alessandra, Allinson, John, Amur, Shashi, Eck, Steve, Green, Cherie, Hedrick, Michael, Hopper, Shirley, Ji, Allena, Joyce, Alison, Litwin, Virginia, Maher, Kevin, Mathews, Joel, Peng, Kun, Safavi, Afshin, Wang, Yow-Ming, Zhang, Yan, Amaravadi, Lakshmi, Palackal, Nisha, Thankamony, Sai, Beaver, Chris, Bame, Eris, Emrich, Thomas, Grimaldi, Christine, Haulenbeek, Jonathan, Kakkanaiah, Vellalore, Lanham, David, Mayer, Andrew, Trampont, Paul C, Vermet, Laurent, Dakappagari, Naveen, Fleener, Catherine, Garofolo, Fabio, Rogers, Cynthia, Tangri, Shabnam, Xu, Yuanxin, Liang, Meina, Rajadhyaksha, Manoj, Richards, Susan, Schweighardt, Becky, Purushothama, Shobha, Baltrukonis, Daniel, Brumm, Jochen, Cherry, Elana, Delcarpini, Jason, Gleason, Carol, Kirshner, Susan, Kubiak, Robert, Pan, Luying, Partridge, Michael, Pedras-Vasconcelos, João, Qu, Qiang, Skibeli, Venke, Saunders, Therese Solstad, Staack, Roland F, Stubenrauch, Kay, Torri, Al, Verthelyi, Daniela, Yan, Haoheng, Gorovits, Boris, Palmer, Rachel, Milton, Mark, Long, Brian, Corsaro, Bart, Farrokhi, Vahid, Fiscella, Michele, Henderson, Neil, Jawa, Vibha, McNally, Jim, Murphy, Rocio, Waldner, Hanspeter, Yang, Tong-Yuan

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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, d... von Gutzmer, R., Stroyakovskiy, D., Gogas, H., Robert, Caroline, Lewis, Karl, Protsenko, Svetlana, Pereira, Rodrigo P., Eigentler, Thomas, Rutkowski, Piotr, Demidov, Lev, Manikhas, Georgy Moiseevich, Yan, Yibing, Huang, Kuan-Chieh, Uyei, Anne, McNally, Virginia, McArthur, Grant A., Ascierto, Paolo A.

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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAF V600 mutation-positive melanoma (IMspire150): primary analysis of the randomised,... von Gutzmer, Ralf, Stroyakovskiy, Daniil, Gogas, Helen, Robert, Caroline, Lewis, Karl, Protsenko, Svetlana, Pereira, Rodrigo P, Eigentler, Thomas, Rutkowski, Piotr, Demidov, Lev, Manikhas, Georgy Moiseevich, Yan, Yibing, Huang, Kuan-Chieh, Uyei, Anne, McNally, Virginia, McArthur, Grant A, Ascierto, Paolo A

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