A randomized phase II study evaluating the combination of carboplatin-based chemotherapy with pertuzumab versus carboplatin-based therapy alone in patients with relapsed, platinum-... von Kaye, S.B., Poole, C.J., Dańska-Bidzińska, A., Gianni, L., Del Conte, G., Gorbunova, V., Novikova, E., Strauss, A., Moczko, M., McNally, V.A., Ross, G., Vergote, I.

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Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening von MCNALLY, V. A, GBAJ, A, DOUGLAS, K. T, STRATFORD, I. J, JAFFAR, M, FREEMAN, S, BRYCE, R. A

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Phase II COLET study: Atezolizumab (A) + cobimetinib (C) + paclitaxel (P)/nab-paclitaxel (nP) as first-line (1L) treatment (tx) for patients (pts) with locally advanced or metastat... von Brufsky, Adam, Kim, Sung-Bae, Zvirbule, Zanete, Dirix, Luc Yves, Eniu, Alexandru E., Carabantes, Francisco, Izarzugaza, Yann, Mebis, Jeroen, Sohn, Joohyuk, Wongchenko, Matthew, Chohan, Saibah, Amin, Reena, McNally, V. A., Miles, David, Loi, Sherene

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COLET (NCT02322814): A multistage, phase 2 study evaluating the safety and efficacy of cobimetinib (C) in combination with paclitaxel (P) as first-line treatment for patients (pts)... von Miles, David, Kim, Sung-Bae, McNally, V. A., Simmons, Brian P., Wongchenko, Matthew, Hsu, Jessie J., Brufsky, Adam M.

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Tumor infiltrating lymphocytes before and after dual HER2 blockade in HER2-amplified early breast cancer: A TRYPHAENA substudy von Ignatiadis, Michail, Van den Eynden, Gert G., Salgado, Roberto, Fornili, Marco, Desmedt, Christine, Holgado, Esther, McNally, V. A., Kiermaier, Astrid Christina, Cortes, Javier, Schneeweiss, Andreas, Willard-Gallo, Karen, Biganzoli, Elia, Sotiriou, Christos

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Cobimetinib (C) + paclitaxel (P) as first-line treatment in patients (pts) with advanced triple-negative breast cancer (TNBC): Updated results and biomarker data from the phase 2 C... von Brufsky, Adam, Kim, Sung-Bae, Velu, Thierry J., Garcia Saenz, Jose Angel, Tan-Chiu, Elizabeth, Sohn, Joohyuk, Dirix, Luc Yves, Vanasek, Jaroslav, Borms, Marleen V., Mingorance, J. Ignacio Delgado, Liu, Mei-Ching, Moezi, Mehdi M., Kozloff, Mark, Sparano, Joseph A., Hsu, Jessie J., Wongchenko, Matthew, Simmons, Brian P., McNally, V. A., Miles, David

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A phase I, dose escalation study to determine the maximum tolerated dose of erlotinib when combined with pertuzumab in previously treated non-small-cell lung cancer patients von Felip, E., Ranson, M., Cedres, S., Dean, E., De Droogh, E., Brewster, M., McNally, V. A., Ross, G., Galdermans, D.

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A randomised phase II study evaluating the combination of carboplatin-based chemotherapy with pertuzumab (P) versus carboplatin-based therapy alone in patients with relapsed, plati... von Kaye, S. B., Poole, C. J., Bidzinksi, M., Gianni, L., Gorbunova, V., Novikova, E., Strauss, A., McNally, V. A., Ross, G., Vergote, I.

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Results of a phase II trial of trastuzumab (H) and pertuzumab (P) in patients (pts) with HER2-positive metastatic breast cancer (MBC) who had progressed during trastuzumab therapy von Gelmon, K. A., Fumoleau, P., Verma, S., Wardley, A. M., Conte, P. F., Miles, D., Gianni, L., McNally, V. A., Ross, G., Baselga, J.

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Synthesis and enzymatic evaluation of pyridinium-Substituted uracil derivatives as novel inhibitors of thymidine phosphorylase von Murray, Paul E, McNally, Virginia A, Lockyer, Stacey D, Williams, Kaye J, Stratford, Ian J, Jaffar, Mohammed, Freeman, Sally

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Fracture-related infection: A consensus on definition from an international expert group von Metsemakers, WJ, Morgenstern, M., McNally, M.A., Moriarty, T.F., McFadyen, I., Scarborough, M., Athanasou, N.A., Ochsner, P.E., Kuehl, R., Raschke, M., Borens, O., Xie, Z., Velkes, S., Hungerer, S., Kates, S.L., Zalavras, C., Giannoudis, P.V., Richards, R.G., Verhofstad, M.H.J.

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Heterobiaryl synthesis by contractive C-C coupling via P(V) intermediates von Hilton, Michael C, Zhang, Xuan, Boyle, Benjamin T, Alegre-Requena, Juan V, Paton, Robert S, McNally, Andrew

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Oxygen redox chemistry without excess alkali-metal ions in Na 2/3 [Mg 0.28 Mn 0.72 ]O 2 von Maitra, Urmimala, House, Robert A, Somerville, James W, Tapia-Ruiz, Nuria, Lozano, Juan G, Guerrini, Niccoló, Hao, Rong, Luo, Kun, Jin, Liyu, Pérez-Osorio, Miguel A, Massel, Felix, Pickup, David M, Ramos, Silvia, Lu, Xingye, McNally, Daniel E, Chadwick, Alan V, Giustino, Feliciano, Schmitt, Thorsten, Duda, Laurent C, Roberts, Matthew R, Bruce, Peter G

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An actin-dependent annexin complex mediates plasma membrane repair in muscle von Demonbreun, Alexis R, Quattrocelli, Mattia, Barefield, David Y, Allen, Madison V, Swanson, Kaitlin E, McNally, Elizabeth M

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Solving the Polyploid Mystery in Health and Disease von Gjelsvik, K.J., Besen-McNally, R., Losick, V.P.

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A phase II randomized trial of cobimetinib plus chemotherapy, with or without atezolizumab, as first-line treatment for patients with locally advanced or metastatic triple-negative... von Brufsky, A., Kim, S.B., Zvirbule, Ž., Eniu, A., Mebis, J., Sohn, J.H., Wongchenko, M., Chohan, S., Amin, R., Yan, Y., McNally, V., Miles, D., Loi, S.

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Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis von Whitehead, Anna, Krause, Fynn N., Moran, Amy, MacCannell, Amanda D. V., Scragg, Jason L., McNally, Ben D., Boateng, Edward, Murfitt, Steven A., Virtue, Samuel, Wright, John, Garnham, Jack, Davies, Graeme R., Dodgson, James, Schneider, Jurgen E., Murray, Andrew J., Church, Christopher, Vidal-Puig, Antonio, Witte, Klaus K., Griffin, Julian L., Roberts, Lee D.

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Pathogen invasion history elucidates contemporary host pathogen dynamics von Vredenburg, Vance T, McNally, Samuel V G, Sulaeman, Hasan, Butler, Helen M, Yap, Tiffany, Koo, Michelle S, Schmeller, Dirk S, Dodge, Celeste, Cheng, Tina, Lau, Gordon, Briggs, Cheryl J

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Phosphorus-mediated sp2–sp3 couplings for C–H fluoroalkylation of azines von Zhang, Xuan, Nottingham, Kyle G., Patel, Chirag, Alegre-Requena, Juan V., Levy, Jeffrey N., Paton, Robert S., McNally, Andrew

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Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early brea... von Schneeweiss, A., Chia, S., Hickish, T., Harvey, V., Eniu, A., Hegg, R., Tausch, C., Seo, J.H., Tsai, Y.-F., Ratnayake, J., McNally, V., Ross, G., Cortés, J.

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