Mechanisms of trinucleotide repeat instability during human development von McMurray, Cynthia T

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Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease von Budworth, Helen, Harris, Faye R, Williams, Paul, Lee, Do Yup, Holt, Amy, Pahnke, Jens, Szczesny, Bartosz, Acevedo-Torres, Karina, Ayala-Peña, Sylvette, McMurray, Cynthia T

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Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice von Polyzos, Aris A., Lee, Do Yup, Datta, Rupsa, Hauser, Meghan, Budworth, Helen, Holt, Amy, Mihalik, Stephanie, Goldschmidt, Pike, Frankel, Ken, Trego, Kelly, Bennett, Michael J., Vockley, Jerry, Xu, Ke, Gratton, Enrico, McMurray, Cynthia T.

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Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts von Polyzos, Aris A., McMurray, Cynthia T.

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A Brief History of Triplet Repeat Diseases von Budworth, Helen, McMurray, Cynthia T.

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XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent von Polyzos, Aris A, Wood, Nigel I, Williams, Paul, Wipf, Peter, Morton, A Jennifer, McMurray, Cynthia T

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Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain von Polyzos, Aris A., Cheong, Ana, Yoo, Jung Hyun, Blagec, Lana, Toprani, Sneh M., Nagel, Zachary D., McMurray, Cynthia T.

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Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease von Xun, Zhiyin, Rivera-Sánchez, Sulay, Ayala-Peña, Sylvette, Lim, James, Budworth, Helen, Skoda, Erin M., Robbins, Paul D., Niedernhofer, Laura J., Wipf, Peter, McMurray, Cynthia T.

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Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans von Sammi, Shreesh Raj, Foguth, Rachel M, Nieves, Claudia Sofía, De Perre, Chloe, Wipf, Peter, McMurray, Cynthia T, Lee, Linda S, Cannon, Jason R

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Features of trinucleotide repeat instability in vivo von Kovtun, Irina V, McMurray, Cynthia T

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OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells von Kovtun, Irina V, Klungland, Arne, Liu, Yuan, Bjoras, Magnar, McMurray, Cynthia T, Wilson, Samuel H

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Trinucleotide expansion in disease: why is there a length threshold? von Lee, Do-Yup, McMurray, Cynthia T

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The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington’s disease von Polyzos, Aris A., McMurray, Cynthia T.

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Folate deficiency drives mitotic missegregation of the human FRAXA locus von Bjerregaard, Victoria A., Garribba, Lorenza, McMurray, Cynthia T., Hickson, Ian D., Liu, Ying

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Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair von Lai, Yanhao, Budworth, Helen, Beaver, Jill M., Chan, Nelson L. S., Zhang, Zunzhen, McMurray, Cynthia T., Liu, Yuan

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Comprehensive macromolecular conformations mapped by quantitative SAXS analyses von Hura, Greg L, Budworth, Helen, Dyer, Kevin N, Rambo, Robert P, Hammel, Michal, McMurray, Cynthia T, Tainer, John A

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An infrared spectral biomarker accurately predicts neurodegenerative disease class in the absence of overt symptoms von Lovergne, Lila, Ghosh, Dhruba, Schuck, Renaud, Polyzos, Aris A., Chen, Andrew D., Martin, Michael C., Barnard, Edward S., Brown, James B., McMurray, Cynthia T.

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Bidirectional transcription of trinucleotide repeats: Roles for excision repair von Budworth, Helen, McMurray, Cynthia T.

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Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes von Polyzos, Aris, Holt, Amy, Brown, Christopher, Cosme, Celica, Wipf, Peter, Gomez-Marin, Alex, Castro, Maríadel R, Ayala-Peña, Sylvette, McMurray, Cynthia T

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Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease von McMurray, Cynthia T.

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