Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors von McMahon, Róisín M., Premkumar, Lakshmanane, Martin, Jennifer L.

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Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development von Christensen, Signe, Halili, Maria A, Strange, Natalie, Petit, Guillaume A, Huston, Wilhelmina M, Martin, Jennifer L, McMahon, Róisín M

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Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase von Christensen, Signe, Grøftehauge, Morten K, Byriel, Karl, Huston, Wilhelmina M, Furlong, Emily, Heras, Begoña, Martin, Jennifer L, McMahon, Róisín M

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Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity von Gor, Mian-Chee, Vezina, Ben, McMahon, Róisín M., King, Gordon J., Panjikar, Santosh, Rehm, Bernd H. A., Martin, Jennifer L., Smith, Andrew T.

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Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo von Ireland, Philip M, McMahon, Róisín M, Marshall, Laura E, Halili, Maria, Furlong, Emily, Tay, Stephanie, Martin, Jennifer L, Sarkar-Tyson, Mitali

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Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1 von Mohanty, Biswaranjan, Rimmer, Kieran, McMahon, Róisín M, Headey, Stephen J, Vazirani, Mansha, Shouldice, Stephen R, Coinçon, Mathieu, Tay, Stephanie, Morton, Craig J, Simpson, Jamie S, Martin, Jennifer L, Scanlon, Martin J

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Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA von Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J, Tay, Stephanie, McMahon, Róisín M, Fairlie, David P, Martin, Jennifer L

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Identification and characterization of two drug‐like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA von Petit, Guillaume A., Mohanty, Biswaranjan, McMahon, Róisín M., Nebl, Stefan, Hilko, David H., Wilde, Karyn L., Scanlon, Martin J., Martin, Jennifer L., Halili, Maria A.

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Opposing effects of HLA class I molecules in tuning autoreactive CD8 + T cells in multiple sclerosis von McMahon, Róisín M, Huygelen, Véronique, Jakobsen, Karen B, Etzensperger, Ruth, Jensen, Lise T, Bell, John I, Friis, Lone, Jones, E Yvonne, Fugger, Lars, Craner, Matthew J, Friese, Manuel A

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Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB von McMahon, Róisín M, Ireland, Philip M, Sarovich, Derek S, Petit, Guillaume, Jenkins, Christopher H, Sarkar-Tyson, Mitali, Currie, Bart J, Martin, Jennifer L

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NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei von Nebl, Stefan, Alwan, Wesam S., Williams, Martin L., Sharma, Gaurav, Taylor, Ashley, Doak, Bradley C., Wilde, Karyn L., McMahon, Róisín M., Halili, Maria A., Martin, Jennifer L., Capuano, Ben, Fenwick, R. Bryn, Mohanty, Biswaranjan, Scanlon, Martin J.

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Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials von Wang, Geqing, Mohanty, Biswaranjan, Williams, Martin L., Doak, Bradley C., Dhouib, Rabeb, Totsika, Makrina, McMahon, Róisín M., Sharma, Gaurav, Zheng, Dan, Bentley, Matthew R., Ka‐Yan Chin, Yanni, Horne, James, Chalmers, David K., Heras, Begoña, Scanlon, Martin J.

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The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis von Wonderen, Jessica H., McMahon, Róisin M., O'Mara, Megan L., McDevitt, Christopher A., Thomson, Andrew J., Kerr, Ian D., MacMillan, Fraser, Callaghan, Richard

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Dissection of the multiple sclerosis associated DR2 haplotype von Etzensperger, Ruth, McMahon, Róisín M, Jones, E. Yvonne, Fugger, Lars

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Structure of HLA-A0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis von McMahon, Róisín M., Friis, Lone, Siebold, Christian, Friese, Manuel A., Fugger, Lars, Jones, E. Yvonne

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Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility von McMahon, Roisin M., Coinçon, Mathieu, Tay, Stephanie, Heras, Begoña, Morton, Craig J., Scanlon, Martin J., Martin, Jennifer L.

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The central cavity of ABCB 1 undergoes alternating access during ATP hydrolysis von van Wonderen, Jessica H., McMahon, Róisin M., O'Mara, Megan L., McDevitt, Christopher A., Thomson, Andrew J., Kerr, Ian D., MacMillan, Fraser, Callaghan, Richard

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ChemInform Abstract: Interrogating Fragments Using a Protein Thermal Shift Assay von McMahon, Roisin M., Scanlon, Martin J., Martin, Jennifer L.

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Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA: e0133805 von Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J, Tay, Stephanie, McMahon, Roisin M, Fairlie, David P, Martin, Jennifer L

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Dissection of the multiple sclerosis associated DR2 haplotype: Mechanisms of Autoimmunity: A Tribute to Professor Ian Mackay von ETZENSPERGER, Ruth, MCMAHON, Roisin M, YVONNE JONES, E, FUGGER, Lars

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