Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies von Mazzulli, Joseph R., Xu, You-Hai, Sun, Ying, Knight, Adam L., McLean, Pamela J., Caldwell, Guy A., Sidransky, Ellen, Grabowski, Gregory A., Krainc, Dimitri

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Exosomal cell-to-cell transmission of alpha synuclein oligomers von Danzer, Karin M, Kranich, Lisa R, Ruf, Wolfgang P, Cagsal-Getkin, Ozge, Winslow, Ashley R, Zhu, Liya, Vanderburg, Charles R, McLean, Pamela J

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α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling von Wang, Lina, Das, Utpal, Scott, David A., Tang, Yong, McLean, Pamela J., Roy, Subhojit

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Protein degradation pathways in Parkinson’s disease: curse or blessing von Ebrahimi-Fakhari, Darius, Wahlster, Lara, McLean, Pamela J.

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Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease von Grozdanov, Veselin, Bousset, Luc, Hoffmeister, Meike, Bliederhaeuser, Corinna, Meier, Christoph, Madiona, Karine, Pieri, Laura, Kiechle, Martin, McLean, Pamela J., Kassubek, Jan, Behrends, Christian, Ludolph, Albert C., Weishaupt, Jochen H., Melki, Ronald, Danzer, Karin M.

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Cellular models of alpha‐synuclein toxicity and aggregation von Delenclos, Marion, Burgess, Jeremy D., Lamprokostopoulou, Agaristi, Outeiro, Tiago F., Vekrellis, Kostas, McLean, Pamela J.

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Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway von Park, Jae-Hyeon, Burgess, Jeremy D., Faroqi, Ayman H., DeMeo, Natasha N., Fiesel, Fabienne C., Springer, Wolfdieter, Delenclos, Marion, McLean, Pamela J.

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Formation of toxic oligomeric alpha-synuclein species in living cells von Outeiro, Tiago Fleming, Putcha, Preeti, Tetzlaff, Julie E, Spoelgen, Robert, Koker, Mirjam, Carvalho, Filipe, Hyman, Bradley T, McLean, Pamela J

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SIRT1 protects against α-synuclein aggregation by activating molecular chaperones von Donmez, Gizem, Arun, Anirudh, Chung, Chee-Yeun, McLean, Pamela J, Lindquist, Susan, Guarente, Leonard

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Biomarkers in Parkinson's disease: Advances and strategies von Delenclos, Marion, Jones, Daryl R, McLean, Pamela J, Uitti, Ryan J

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Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates von Jiang, Peizhou, Gan, Ming, Yen, Shu-Hui, McLean, Pamela J., Dickson, Dennis W.

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Chaperones in Neurodegeneration von Lindberg, Iris, Shorter, James, Wiseman, R Luke, Chiti, Fabrizio, Dickey, Chad A, McLean, Pamela J

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Optimizing SH-SY5Y cell culture: exploring the beneficial effects of an alternative media supplement on cell proliferation and viability von Kaya, Zeynep Bengisu, Santiago-Padilla, Valeria, Lim, Melina, Boschen, Suelen L., Atilla, Pergin, McLean, Pamela J.

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Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5) von Kalia, Lorraine V, Kalia, Suneil K, Chau, Hien, Lozano, Andres M, Hyman, Bradley T, McLean, Pamela J

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α-Synuclein oligomers and clinical implications for Parkinson disease von Kalia, Lorraine V., Kalia, Suneil K., McLean, Pamela J., Lozano, Andres M., Lang, Anthony E.

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Self as coach, self as leader: developing the best in you to develop the best in others von McLean, Pamela

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CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage von Sun, Jichao, Carlson-Stevermer, Jared, Das, Utpal, Shen, Minjie, Delenclos, Marion, Snead, Amanda M., Koo, So Yeon, Wang, Lina, Qiao, Dianhua, Loi, Jonathan, Petersen, Andrew J., Stockton, Michael, Bhattacharyya, Anita, Jones, Mathew V., Zhao, Xinyu, McLean, Pamela J., Sproul, Andrew A., Saha, Krishanu, Roy, Subhojit

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Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein von Ebrahimi-Fakhari, Darius, Cantuti-Castelvetri, Ippolita, Fan, Zhanyun, Rockenstein, Edward, Masliah, Eliezer, Hyman, Bradley T, McLean, Pamela J, Unni, Vivek K

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Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease von Theodore, Shaji, Cao, Shuwen, McLean, Pamela J, Standaert, David G

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Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson's disease von Bhattarai, Yogesh, Si, Jie, Pu, Meng, Ross, Owen A., McLean, Pamela J., Till, Lisa, Moor, William, Grover, Madhusudan, Kandimalla, Karunya K., Margolis, Kara G., Farrugia, Gianrico, Kashyap, Purna C.

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