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Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria von Kokkonda, Sreekanth, Deng, Xiaoyi, White, Karen L, El Mazouni, Farah, White, John, Shackleford, David M, Katneni, Kasiram, Chiu, Francis C. K, Barker, Helena, McLaren, Jenna, Crighton, Elly, Chen, Gong, Angulo-Barturen, Inigo, Jimenez-Diaz, Maria Belen, Ferrer, Santiago, Huertas-Valentin, Leticia, Martinez-Martinez, Maria Santos, Lafuente-Monasterio, Maria Jose, Chittimalla, Rajesh, Shahi, Shatrughan P, Wittlin, Sergio, Waterson, David, Burrows, Jeremy N, Matthews, Dave, Tomchick, Diana, Rathod, Pradipsinh K, Palmer, Michael J, Charman, Susan A, Phillips, Margaret A

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Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 von Shackleford, David M, Chiu, Francis C. K, Katneni, Kasiram, Blundell, Scott, McLaren, Jenna, Wang, Xiaofang, Zhou, Lin, Sriraghavan, Kamaraj, Alker, André M, Hunziker, Daniel, Scheurer, Christian, Zhao, Qingjie, Dong, Yuxiang, Möhrle, Jörg J, Abla, Nada, Matile, Hugues, Wittlin, Sergio, Vennerstrom, Jonathan L, Charman, Susan A

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Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12) von Dong, Yuxiang, Sonawane, Yogesh, Maher, Steven P, Zeeman, Anne-Marie, Chaumeau, Victor, Vantaux, Amélie, Cooper, Caitlin A, Chiu, Francis C. K, Ryan, Eileen, McLaren, Jenna, Chen, Gong, Wittlin, Sergio, Witkowski, Benoît, Nosten, François, Sriraghavan, Kamaraj, Kyle, Dennis E, Kocken, Clemens H. M, Charman, Susan A, Vennerstrom, Jonathan L

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