CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis von Gillmore, Julian D, Gane, Ed, Taubel, Jorg, Kao, Justin, Fontana, Marianna, Maitland, Michael L, Seitzer, Jessica, O’Connell, Daniel, Walsh, Kathryn R, Wood, Kristy, Phillips, Jonathan, Xu, Yuanxin, Amaral, Adam, Boyd, Adam P, Cehelsky, Jeffrey E, McKee, Mark D, Schiermeier, Andrew, Harari, Olivier, Murphy, Andrew, Kyratsous, Christos A, Zambrowicz, Brian, Soltys, Randy, Gutstein, David E, Leonard, John, Sepp-Lorenzino, Laura, Lebwohl, David

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Addition of the PARP inhibitor veliparib plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (BrighTNess): a randomised, pha... von Loibl, Sibylle, O'Shaughnessy, Joyce, Untch, Michael, Sikov, William M, Rugo, Hope S, McKee, Mark D, Huober, Jens, Golshan, Mehra, von Minckwitz, Gunter, Maag, David, Sullivan, Danielle, Wolmark, Norman, McIntyre, Kristi, Ponce Lorenzo, Jose J, Metzger Filho, Otto, Rastogi, Priya, Symmans, W Fraser, Liu, Xuan, Geyer, Charles E

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Monobenzyl Ether of Hydroquinone and 4-Tertiary Butyl Phenol Activate Markedly Different Physiological Responses in Melanocytes: Relevance to Skin Depigmentation von Hariharan, Vidhya, Klarquist, Jared, Reust, Mary J., Koshoffer, Amy, McKee, Mark D., Boissy, Raymond E., Caroline Le Poole, I.

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Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trial von Cainap, Calin, Qin, Shukui, Huang, Wen-Tsung, Chung, Ik Joo, Pan, Hongming, Cheng, Ying, Kudo, Masatoshi, Kang, Yoon-Koo, Chen, Pei-Jer, Toh, Han-Chong, Gorbunova, Vera, Eskens, Ferry A L M, Qian, Jiang, McKee, Mark D, Ricker, Justin L, Carlson, Dawn M, El-Nowiem, Saied

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Breast Conservation After Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: Surgical Results From the BrighTNess Randomized Clinical Trial von Golshan, Mehra, Loibl, Sibylle, Wong, Stephanie M, Huober, Jens Bodo, O’Shaughnessy, Joyce, Rugo, Hope S, Wolmark, Norman, McKee, Mark D, Maag, David, Sullivan, Danielle M, Metzger-Filho, Otto, Von Minckwitz, Gunter, Geyer, Charles E, Sikov, William M, Untch, Michael

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CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema von Longhurst, Hilary J., Lindsay, Karen, Petersen, Remy S., Fijen, Lauré M., Gurugama, Padmalal, Maag, David, Butler, James S., Shah, Mrinal Y., Golden, Adele, Xu, Yuanxin, Boiselle, Carri, Vogel, Joseph D., Abdelhady, Ahmed M., Maitland, Michael L., McKee, Mark D., Seitzer, Jessica, Han, Bo W., Soukamneuth, Samantha, Leonard, John, Sepp-Lorenzino, Laura, Clark, Eliana D., Lebwohl, David, Cohn, Danny M.

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Phase I combination study of the PARP inhibitor veliparib plus carboplatin and gemcitabine in patients with advanced ovarian cancer and other solid malignancies von Gray, Heidi J., Bell-McGuinn, Katherine, Fleming, Gini F., Cristea, Mihaela, Xiong, Hao, Sullivan, Danielle, Luo, Yan, McKee, Mark D., Munasinghe, Wijith, Martin, Lainie P.

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Reply to M. Bouattour et al von Cainap, Calin, McKee, Mark D, Ricker, Justin L

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Randomized phase II study of carboplatin and paclitaxel with either linifanib or placebo for advanced nonsquamous non-small-cell lung cancer von Ramalingam, Suresh S, Shtivelband, Mikhail, Soo, Ross A, Barrios, Carlos H, Makhson, Anatoly, Segalla, José G M, Pittman, Kenneth B, Kolman, Petr, Pereira, Jose R, Srkalovic, Gordan, Belani, Chandra P, Axelrod, Rita, Owonikoko, Taofeek K, Qin, Qin, Qian, Jiang, McKeegan, Evelyn M, Devanarayan, Viswanath, McKee, Mark D, Ricker, Justin L, Carlson, Dawn M, Gorbunova, Vera A

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T cell avidity and tumor recognition: implications and therapeutic strategies von McKee, Mark D, Roszkowski, Jeffrey J, Nishimura, Michael I

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Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors von Creelan, Ben C, Gabrilovich, Dmitry I, Gray, Jhanelle E, Williams, Charles C, Tanvetyanon, Tawee, Haura, Eric B, Weber, Jeffrey S, Gibney, Geoffrey T, Markowitz, Joseph, Proksch, Joel W, Reisman, Scott A, McKee, Mark D, Chin, Melanie P, Meyer, Colin J, Antonia, Scott J

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Plasma biomarker signature associated with improved survival in advanced non-small cell lung cancer patients on linifanib von McKeegan, Evelyn M, Ansell, Peter J, Davis, Gerard, Chan, Sabrina, Chandran, Raj K, Gawel, Susan H, Dowell, Barry L, Bhathena, Anahita, Chakravartty, Arunava, McKee, Mark D, Ricker, Justin L, Carlson, Dawn M, Ramalingam, Suresh S, Devanarayan, Viswanath

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Phase 1 dose escalation trial of ilorasertib, a dual Aurora/VEGF receptor kinase inhibitor, in patients with hematologic malignancies von Garcia-Manero, Guillermo, Tibes, Raoul, Kadia, Tapan, Kantarjian, Hagop, Arellano, Martha, Knight, Emily A., Xiong, Hao, Qin, Qin, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Albert, Daniel H., Oliver, Brian, McKee, Mark D., Ricker, Justin L., Khoury, Hanna Jean

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The prognostic significance of margin width for extremity and trunk sarcoma von Mc Kee, Mark D., Liu, Dong Feng, Brooks, John J., Gibbs, John F., Driscoll, Deborah L., Kraybill, William G.

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A phase 1 study of linifanib in combination with carboplatin/paclitaxel as first-line treatment of Japanese patients with advanced or metastatic non-small cell lung cancer (NSCLC) von Horinouchi, Hidehito, Yamamoto, Noboru, Nokihara, Hiroshi, Horai, Takeshi, Nishio, Makoto, Ohyanagi, Fumiyoshi, Horiike, Atsushi, Nakagawa, Kazuhiko, Terashima, Masaaki, Okabe, Takafumi, Kaneda, Hiroyasu, McKee, Mark D., Carlson, Dawn M., Xiong, Hao, Tamura, Tomohide

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Pancreaticobiliary reflux and gallbladder cancer von McKee, Mark D.

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Randomized Phase II Open-Label Study of mFOLFOX6 in Combination With Linifanib or Bevacizumab for Metastatic Colorectal Cancer von O'Neil, Bert H, Cainap, Calin, Van Cutsem, Eric, Gorbunova, Vera, Karapetis, Christos S, Berlin, Jordan, Goldberg, Richard M, Qin, Qin, Qian, Jiang, Ricker, Justin L, Fischer, JuDee, McKee, Mark D, Carlson, Dawn M, Kim, Tae Won

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An open-label, phase 1 study evaluating safety, tolerability, and pharmacokinetics of linifanib (ABT-869) in Japanese patients with solid tumors von Asahina, Hajime, Tamura, Yosuke, Nokihara, Hiroshi, Yamamoto, Noboru, Seki, Yoshitaka, Shibata, Takashi, Goto, Yasushi, Tanioka, Maki, Yamada, Yasuhide, Coates, Andrew, Chiu, Yi-Lin, Li, Xiaohui, Pradhan, Rajendra, Ansell, Peter J., McKeegan, Evelyn M., McKee, Mark D., Carlson, Dawn M., Tamura, Tomohide

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Melanoma-Associated Antigen Expression in Lymphangioleiomyomatosis Renders Tumor Cells Susceptible to Cytotoxic T Cells von Klarquist, Jared, Barfuss, Allison, Kandala, Sridhar, Reust, Mary J, Braun, Ruedi K, Hu, Jennifer, Dilling, Daniel F, McKee, Mark D, Boissy, Raymond E, Love, Robert B, Nishimura, Michael I, Le Poole, I. Caroline

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Identification of a hepatitis C virus-reactive T cell receptor that does not require CD8 for target cell recognition von CALLENDER, Glenda G, ROSEN, Hugo R, ROSZKOWSKI, Jeffrey J, LYONS, Gretchen E, MINGLI LI, MOORE, Tamson, BRASIC, Natasha, MCKEE, Mark D, NISHIMURA, Michael I

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