Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA von Blakney, Anna K., McKay, Paul F., Yus, Bárbara Ibarzo, Aldon, Yoann, Shattock, Robin J.

Volltext

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice von McKay, Paul F., Hu, Kai, Blakney, Anna K., Samnuan, Karnyart, Brown, Jonathan C., Penn, Rebecca, Zhou, Jie, Bouton, Clément R., Rogers, Paul, Polra, Krunal, Lin, Paulo J. C., Barbosa, Christopher, Tam, Ying K., Barclay, Wendy S., Shattock, Robin J.

Volltext

Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines von Blakney, Anna K., McKay, Paul F., Hu, Kai, Samnuan, Karnyart, Jain, Nikita, Brown, Andrew, Thomas, Anitha, Rogers, Paul, Polra, Krunal, Sallah, Hadijatou, Yeow, Jonathan, Zhu, Yunqing, Stevens, Molly M., Geall, Andrew, Shattock, Robin J.

Volltext

Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice von Spencer, Alexandra J., McKay, Paul F., Belij-Rammerstorfer, Sandra, Ulaszewska, Marta, Bissett, Cameron D., Hu, Kai, Samnuan, Karnyart, Blakney, Anna K., Wright, Daniel, Sharpe, Hannah R., Gilbride, Ciaran, Truby, Adam, Allen, Elizabeth R., Gilbert, Sarah C., Shattock, Robin J., Lambe, Teresa

Volltext

Innate Inhibiting Proteins Enhance Expression and Immunogenicity of Self-Amplifying RNA von Blakney, Anna K., McKay, Paul F., Bouton, Clément R., Hu, Kai, Samnuan, Karnyart, Shattock, Robin J.

Volltext

Advances in HIV-1 Vaccine Development von Gao, Yong, McKay, Paul F, Mann, Jamie F S

Volltext

Effects of cationic adjuvant formulation particle type, fluidity and immunomodulators on delivery and immunogenicity of saRNA von Blakney, Anna K., McKay, Paul F., Christensen, Dennis, Yus, Bárbara Ibarzo, Aldon, Yoann, Follmann, Frank, Shattock, Robin J.

Volltext

An Overview of Rift Valley Fever Vaccine Development Strategies von Kitandwe, Paul Kato, McKay, Paul F, Kaleebu, Pontiano, Shattock, Robin J

Volltext

Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers von Aldon, Yoann, McKay, Paul F., Allen, Joel, Ozorowski, Gabriel, Felfödiné Lévai, Réka, Tolazzi, Monica, Rogers, Paul, He, Linling, de Val, Natalia, Fábián, Katalin, Scarlatti, Gabriella, Zhu, Jiang, Ward, Andrew B., Crispin, Max, Shattock, Robin J.

Volltext

A self-amplifying RNA vaccine provides protection in a murine model of bubonic plague von Shattock, Robin John, Andrianaivoarimanana, Voahangy, McKay, Paul F., Randriantseheno, Lovasoa Nomena, Murugaiah, Valarmathy, Samnuan, K., Rogers, Paul, Tregoning, John S., Rajerison, Minoarisoa, Moore, Kristoffer M., Laws, Thomas Robert, Williamson, E. Diane

Volltext

A sort and sequence approach to dissect heterogeneity of response to a self-amplifying RNA vector in a novel human muscle cell line von Barton, Rachel D., Tregoning, John S., Wang, Ziyin, Gonçalves-Carneiro, Daniel, Patel, Radhika, McKay, Paul F., Shattock, Robin J.

Volltext

Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines von Tregoning, John S., Stirling, David C., Wang, Ziyin, Flight, Katie E., Brown, Jonathan C., Blakney, Anna K., McKay, Paul F., Cunliffe, Robert F., Murugaiah, Valarmathy, Fox, Christopher B., Beattie, Mitchell, Tam, Ying K., Johansson, Cecilia, Shattock, Robin J.

Volltext

Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model von Lorenzen, Emma, Contreras, Vanessa, Olsen, Anja W, Andersen, Peter, Desjardins, Delphine, Rosenkrands, Ida, Juel, Helene Bæk, Delache, Benoit, Langlois, Sebastien, Delaugerre, Constance, Joubert, Christophe, Dereuddre-Bosquet, Nathalie, Bébéar, Cécile, De Barbeyrac, Bertille, Touati, Arabella, McKay, Paul F, Shattock, Robin J, Le Grand, Roger, Follmann, Frank, Dietrich, Jes

Volltext

Chlamydia trachomatis: Cell biology, immunology and vaccination von Murray, Sam M., McKay, Paul F.

Volltext

Increasing human monoclonal antibody cloning efficiency with a whole-cell modified immunoglobulin-capture assay (mICA) von Siris, Sara, Gladstone, Camilla A, Guo, Yanping, Patel, Radhika, Pinder, Christopher L, Shattock, Robin J, McKay, Paul F, Langford, Paul R, Bidmos, Fadil A

Volltext

Immunogenicity of stabilized HIV-1 Env trimers delivered by self-amplifying mRNA von Aldon, Yoann, McKay, Paul F., Moreno Herrero, Jorge, Vogel, Annette B., Lévai, Réka, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Haas, Heinrich, Fábián, Katalin, Le Grand, Roger, Sahin, Ugur, Shattock, Robin J.

Volltext

TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes von McKay, Paul F, King, Deborah F L, Mann, Jamie F S, Barinaga, Guillermo, Carter, Darrick, Shattock, Robin J

Volltext

Structural Components for Amplification of Positive and Negative Strand VEEV Splitzicons von Blakney, Anna K, McKay, Paul F, Shattock, Robin J

Volltext

Identification of potential biomarkers of vaccine inflammation in mice von McKay, Paul F, Cizmeci, Deniz, Aldon, Yoann, Maertzdorf, Jeroen, Weiner, January, Kaufmann, Stefan He, Lewis, David Jm, van den Berg, Robert A, Del Giudice, Giuseppe, Shattock, Robin J

Volltext

Presentation of antigen on extracellular vesicles using transmembrane domains from viral glycoproteins for enhanced immunogenicity von Hu, Kai, McKay, Paul F., Samnuan, Karnyart, Najer, Adrian, Blakney, Anna K., Che, Junyi, O'Driscoll, Gwen, Cihova, Martina, Stevens, Molly M., Shattock, Robin J.

Volltext