From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs von McIntyre, Rebecca L, Daniels, Eileen G, Molenaars, Marte, Houtkooper, Riekelt H, Janssens, Georges E

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Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion von Liu, Yasmine J, Janssens, Georges E, McIntyre, Rebecca L, Molenaars, Marte, Kamble, Rashmi, Gao, Arwen W, Jongejan, Aldo, Weeghel, Michel van, MacInnes, Alyson W, Houtkooper, Riekelt H

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Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models von Costa-Machado, Luis Filipe, Garcia-Dominguez, Esther, McIntyre, Rebecca L., Lopez-Aceituno, Jose Luis, Ballesteros-Gonzalez, Álvaro, Tapia-Gonzalez, Andrea, Fabregat-Safont, David, Eisenberg, Tobias, Gomez, Jesús, Plaza, Adrian, Sierra-Ramirez, Aranzazu, Perez, Manuel, Villanueva-Bermejo, David, Fornari, Tiziana, Loza, María Isabel, Herradon, Gonzalo, Hofer, Sebastian J., Magnes, Christoph, Madeo, Frank, Duerr, Janet S., Pozo, Oscar J., Galindo, Maximo-Ibo, del Pino, Isabel, Houtkooper, Riekelt H., Megias, Diego, Viña, Jose, Gomez-Cabrera, Mari Carmen, Fernandez-Marcos, Pablo J.

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Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction von van der Rijt, Sanne, Molenaars, Marte, McIntyre, Rebecca L., Janssens, Georges E., Houtkooper, Riekelt H.

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Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4 von McIntyre, Rebecca L., Molenaars, Marte, Schomakers, Bauke V., Gao, Arwen W., Kamble, Rashmi, Jongejan, Aldo, van Weeghel, Michel, van Kuilenburg, André B.P., Possemato, Richard, Houtkooper, Riekelt H., Janssens, Georges E.

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Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease von Liu, Yasmine J., McIntyre, Rebecca L., Janssens, Georges E., Houtkooper, Riekelt H.

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Considerations Regarding Public Use of Longevity Interventions von Liu, Yasmine J, McIntyre, Rebecca L, Janssens, Georges E

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Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging von McIntyre, Rebecca L., Rahman, Mizanur, Vanapalli, Siva A., Houtkooper, Riekelt H., Janssens, Georges E.

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Cutting through dogma: a novel tool to dissect lactate biology von Rausch, Niclas, McIntyre, Rebecca L., Finger, Fabian, Lund, Jens

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Low-dose naltrexone extends healthspan and lifespan in C. elegans via SKN-1 activation von Li, Weisha, McIntyre, Rebecca L., Schomakers, Bauke V., Kamble, Rashmi, Luesink, Anne H.G., van Weeghel, Michel, Houtkooper, Riekelt H., Gao, Arwen W., Janssens, Georges E.

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Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice von Zapata‐Pérez, Rubén, Tammaro, Alessandra, Schomakers, Bauke V., Scantlebery, Angelique M. L., Denis, Simone, Elfrink, Hyung L., Giroud‐Gerbetant, Judith, Cantó, Carles, López‐Leonardo, Carmen, McIntyre, Rebecca L., van Weeghel, Michel, Sánchez‐Ferrer, Álvaro, Houtkooper, Riekelt H.

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Repurposing nucleoside reverse transcriptase inhibitors (NRTIs) to slow aging von Brochard, Thomas, McIntyre, Rebecca L, Houtkooper, Riekelt H, Seluanov, Andrei, Gorbunova, Vera, Janssens, Georges E

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Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30 von Liu, Yasmine J., McIntyre, Rebecca L., Janssens, Georges E., Williams, Evan G., Lan, Jiayi, van Weeghel, Michel, Schomakers, Bauke, van der Veen, Henk, van der Wel, Nicole N., Yao, Pallas, Mair, William B., Aebersold, Ruedi, MacInnes, Alyson W., Houtkooper, Riekelt H.

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Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity von McIntyre, Rebecca L., Liu, Yasmine J., Hu, Man, Morris, Brian J., Willcox, Bradley J., Donlon, Timothy A., Houtkooper, Riekelt H., Janssens, Georges E.

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Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF‐16‐induced longevity von McIntyre, Rebecca L., Denis, Simone W., Kamble, Rashmi, Molenaars, Marte, Petr, Michael, Schomakers, Bauke V., Rahman, Mizanur, Gupta, Siddhartha, Toth, Marton L., Vanapalli, Siva A., Jongejan, Aldo, Scheibye‐Knudsen, Morten, Houtkooper, Riekelt H., Janssens, Georges E.

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CIAO1 and MMS19 deficiency: A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders von van Karnebeek, Clara D.M., Tarailo-Graovac, Maja, Leen, René, Meinsma, Rutger, Correard, Solenne, Jansen-Meijer, Judith, Prykhozhij, Sergey V., Pena, Izabella A., Ban, Kevin, Schock, Sarah, Saxena, Vishal, Pras-Raves, Mia L., Drögemöller, Britt I., Grootemaat, Anita E., van der Wel, Nicole N., Dobritzsch, Doreen, Roseboom, Winfried, Schomakers, Bauke V., Jaspers, Yorrick R.J., Zoetekouw, Lida, Roelofsen, Jeroen, Ferreira, Carlos R., van der Lee, Robin, Ross, Colin J., Kochan, Jakub, McIntyre, Rebecca L., van Klinken, Jan B., van Weeghel, Michel, Kramer, Gertjan, Weschke, Bernhard, Labrune, Philippe, Willemsen, Michèl A., Riva, Daria, Garavaglia, Barbara, Moeschler, John B., Filiano, James J., Ekker, Marc, Berman, Jason N., Dyment, David, Vaz, Frédéric M., Wasserman, Wyeth W., Houtkooper, Riekelt H., van Kuilenburg, André B.P.

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Akt and mTORC1 Have Different Roles During Liver Tumorigenesis in Mice von Kenerson, Heidi L, Yeh, Matthew M, Kazami, Machiko, Jiang, Xiuyun, Riehle, Kimberly J, McIntyre, Rebecca L, Park, James O, Kwon, Steve, Campbell, Jean S, Yeung, Raymond S

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Polybrominated diphenyl ether congener, BDE-47, impairs insulin sensitivity in mice with liver-specific Pten deficiency von McIntyre, Rebecca L, Kenerson, Heidi L, Subramanian, Savitha, Wang, Shari A, Kazami, Machiko, Stapleton, Heather M, Yeung, Raymond S

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CIAO1 and MMS19 de fi ciency: A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders von van Karnebeek, Clara D. M., Tarailo-Graovac, Maja, Leen, Rene, Meinsma, Rutger, Correard, Solenne, Jansen-Meijer, Judith, Prykhozhij, Sergey V., Pena, Izabella A., Ban, Kevin, Schock, Sarah, Saxena, Vishal, Pras-Raves, Mia L., Drogemoller, Britt I., Grootemaat, Anita E., van der Wel, Nicole N., Dobritzsch, Doreen, Roseboom, Winfried, Schomakers, Bauke V., Jaspers, Yorrick R. J., Zoetekouw, Lida, Roelofsen, Jeroen, Ferreira, Carlos R., van der Lee, Robin, Ross, Colin J., Kochan, Jakub, McIntyre, Rebecca L., van Klinken, Jan B., van Weeghel, Michel, Kramer, Gertjan, Weschke, Bernhard, Labrune, Philippe, Willemsen, Michel A., Riva, Daria, Garavaglia, Barbara, Moeschler, John B., Filiano, James J., Ekker, Marc, Berman, Jason N., Dyment, David, Vaz, Frederic M., Wassermann, Wyeth W., Houtkooper, Riekelt H., van Kuilenburg, Andre B. P.

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CIAO1 and MMS19 de fi ciency : A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders von van Karnebeek, Clara D. M, Tarailo-Graovac, Maja, Leen, Rene, Meinsma, Rutger, Correard, Solenne, Jansen-Meijer, Judith, Prykhozhij, Sergey V, Pena, Izabella A, Ban, Kevin, Schock, Sarah, Saxena, Vishal, Pras-Raves, Mia L, Drogemoller, Britt I, Grootemaat, Anita E, van der Wel, Nicole N, Dobritzsch, Doreen, Roseboom, Winfried, Schomakers, Bauke V, Jaspers, Yorrick R. J, Zoetekouw, Lida, Roelofsen, Jeroen, Ferreira, Carlos R, van der Lee, Robin, Ross, Colin J, Kochan, Jakub, McIntyre, Rebecca L, van Klinken, Jan B, van Weeghel, Michel, Kramer, Gertjan, Weschke, Bernhard, Labrune, Philippe, Willemsen, Michel A, Riva, Daria, Garavaglia, Barbara, Moeschler, John B, Filiano, James J, Ekker, Marc, Berman, Jason N, Dyment, David, Vaz, Frederic M, Wassermann, Wyeth W, Houtkooper, Riekelt H, van Kuilenburg, Andre B. P

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