Adenovirus Type 5 Rupture of Lysosomes Leads to Cathepsin B-Dependent Mitochondrial Stress and Production of Reactive Oxygen Species von MCGUIRE, Kathleen A, BARLAN, Arlene U, GRIFFIN, Tina M, WIETHOFF, Christopher M

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New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission von McGuire, Kathleen A, Miura, Kazutoyo, Wiethoff, Christopher M, Williamson, Kim C

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Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications von Patel, Shitalben, Karlsson, Marie, Klahn, Joseph T., Gambino, Frank, Costa, Helena, McGuire, Kathleen A., Baumgartner, Christina K., Williams, Jon, Sandoz, Sarah, Kath, James E.

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PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity von Juneja, Vikram R, McGuire, Kathleen A, Manguso, Robert T, LaFleur, Martin W, Collins, Natalie, Haining, W Nicholas, Freeman, Gordon J, Sharpe, Arlene H

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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity von Baumgartner, Christina K., Ebrahimi-Nik, Hakimeh, Iracheta-Vellve, Arvin, Hamel, Keith M., Olander, Kira E., Davis, Thomas G. R., McGuire, Kathleen A., Halvorsen, Geoff T., Avila, Omar I., Patel, Chirag H., Kim, Sarah Y., Kammula, Ashwin V., Muscato, Audrey J., Halliwill, Kyle, Geda, Prasanthi, Klinge, Kelly L., Xiong, Zhaoming, Duggan, Ryan, Mu, Liang, Yeary, Mitchell D., Patti, James C., Balon, Tyler M., Mathew, Rebecca, Backus, Carey, Kennedy, Domenick E., Chen, Angeline, Longenecker, Kenton, Klahn, Joseph T., Hrusch, Cara L., Krishnan, Navasona, Hutchins, Charles W., Dunning, Jax P., Bulic, Marinka, Tiwari, Payal, Colvin, Kayla J., Chuong, Cun Lan, Kohnle, Ian C., Rees, Matthew G., Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A., Wu, Meng-Ju, Suermondt, Juliette S. M. T., Knudsen, Nelson H., Cheruiyot, Collins K., Sen, Debattama R., Griffin, Gabriel K., Golub, Todd R., El-Bardeesy, Nabeel, Decker, Joshua H., Yang, Yi, Guffroy, Magali, Fossey, Stacey, Trusk, Patricia, Sun, Im-Meng, Liu, Yue, Qiu, Wei, Sun, Qi, Paddock, Marcia N., Farney, Elliot P., Matulenko, Mark A., Beauregard, Clay, Frost, Jennifer M., Yates, Kathleen B., Kym, Philip R., Manguso, Robert T.

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Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses von Bu, Xia, Juneja, Vikram R., Reynolds, Carol G., Mahoney, Kathleen M., Bu, Melissa T., McGuire, Kathleen A., Maleri, Seth, Hua, Ping, Zhu, Baogong, Klein, Sarah R., Greenfield, Edward A., Armand, Philippe, Ritz, Jerome, Sharpe, Arlene H., Freeman, Gordon J.

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999 The PTPN2/N1 small molecule inhibitor ABBV-CLS-484 promotes NK cell activity driving primary tumor regression and preventing metastasis von Patel, Chirag, McGuire, Kathleen A, Ebrahimi-Nik, Hakimeh, Sun, Meng, Liu, Yue, Klinge, Kelly, Aguado, Jacqueline, Muscato, Audrey J, Tiwari, Payal, Avila-Monge, Omar, Colvin, Kayla J, Olander, Kira, Halliwill, Kyle, Klahn, Joseph, Schutte, Alexander, Paddock, Marcia N, Powell, Jonathan, Hamel, Keith M, Frost, Jennifer M, Yates, Kathleen B, Kym, Philip R, Manguso, Robert T, Baumgartner, Christina K

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1403-A PTPN2/N1 inhibitor ABBV-CLS-484 unleashes potent anti-tumor immunity von Ebrahimi-Nik, Hakimeh, Baumgartner, Christina K, Iracheta-Vellve, Arvin, Hamel, Keith M, Olander, Kira, Davis, Thomas GR, McGuire, Kathleen A, Halvorsen, Geoff T, Avila, Omar I, Patel, Chirag, Kim, Sarah, Kammula, Ashwin V, Muscato, Audrey J, Halliwill, Kyle, Geda, Prasanthi, Klinge, Kelly, Xiong, Zhaoming, Duggan, Ryan, Mu, Liang, Yeary, Mitchell D, Patti, James C, Balon, Tyler M, Mathew, Rebecca, Backus, Carey, Kennedy, Domenick, Chen, Angeline, Longenecker, Kenton, Klahn, Joseph, Hrusch, Cara, Krishnan, Navasona, Hutchins, Charles W, Aguado, Jacqueline, Bulic, Marinka, Tiwari, Payal, Colvin, Kayla J, Chuong, Cun Lan, Kohnle, Ian C, Rees, Matthew G, Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A, Wu, Meng-Ju, Sen, Debattama R, Griffin, Gabriel K, El-Bardeesy, Nabeel, Trusk, Patricia, Sun, Meng, Liu, Yue, Decker, Joshua H, Yang, Yi, Fossey, Stacey, Qiu, Wei, Sun, Qi, Paddock, Marcia N, Farney, Elliot P, Beauregard, Clay, Frost, Jennifer M, Yates, Kathleen B, Kym, Philip R, Manguso, Robert T

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Monitoring PD-1 Signaling in Tumor Infiltrating Lymphocytes von Bu, Xia, Juneja, Vikram R., Mahoney, Katheleen M., Renolds, Carol G., Mcguire, Kathleen A., Maleri, Seth, Hua, Ping, Zhu, Baogong, Klein, Sarah R, Greenfield, Edward, Armand, Philippe, Ritz, Jerome, Sharpe, Arlene, Freeman, Gordon J

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Monitoring PD-1 phosphorylation to evaluate PD-1 signaling during anti-tumor immune responses von Bu, Xia, Juneja, Vikram R., Reynolds, Carol G., Mahoney, Kathleen M., Bu, Melissa T., McGuire, Kathleen A., Maleri, Seth, Hua, Ping, Zhu, Baogong, Klein, Sarah R., Greenfield, Edward A., Armand, Philippe, Ritz, Jerome, Sharpe, Arlene H., Freeman, Gordon J.

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Abstract A41: Small molecule inhibition of PTPN2/1 inflames the tumour microenvironment and unleashes potent CD8+ T cell immunity von Ebrahimi-Nik, Hakimeh, Iracheta-Vellve, Arvin, Olander, Kira E., Davis, Thomas R.G., Kim, Sarah Y., Yeary, Mitchell D., Patti, James C., Balon, Tyler M., Avila, Omar Ismail, Chuong, Cun Lan, Wu, Meng-Ju, Baumgartner, Christina K., Hamel, Keith M., McGuire, Kathleen A., Mathew, Rebecca, Backus, Carey, Kohnle, Ian C., Xiong, Zhaoming, Farney, Elliot P., Frost, Jennifer M., Halvorsen, Geoff T., Rees, Matthew, Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A., Golub, Todd R., Griffin, Gabriel K., El-Bardeesy, Nabeel, Beauregard, Clay C., Kym, Philip R., Yates, Kathleen B., Manguso, Robert T.

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Abstract ND06: ABBV-CLS-484: An active site PTPN2/N1 inhibitor that augments the immune response and sensitizes tumors to immune-mediated killing von Baumgartner, Christina K., Paddock, Marcia N., Frost, Jennifer M., Hamel, Keith M., McGuire, Kathleen A., Halliwill, Kyle, Xiong, Zhaoming, Mu, Liang, Klinge, Kelly, Geda, Prasanthi, Aguado, Jaqueline, Bulic, Marinka, Farney, Elliot P., Yates, Kathleen B., Manguso, Robert T., Beauregard, Clay, Kym, Philip R.

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Abstract 606: Targeting the immune checkpoint PTPN2 with ABBV-CLS-484 inflames the tumor microenvironment and unleashes potent CD8+ T cell immunity von Iracheta-Vellve, Arvin, Ebrahimi-Nik, Hakimeh, Davis, Thomas R., Olander, Kira E., Kim, Sarah Y., Yeary, Mitchell D., Patti, James C., Kohnle, Ian C., Baumgartner, Christina K., Hamel, Keith M., McGuire, Kathleen A., Chuong, Cun Lan, Xiong, Zhaoming, Farney, Elliot P., Frost, Jennifer M., Rees, Matthew, Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A., Golub, Todd R., Griffin, Gabriel K., Beauregard, Clay, Kym, Philip R., Yates, Kathleen B., Manguso, Robert T.

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Abstract A097: Tumor PDL1 blocks CTL cytotoxicity von McGuire, Kathleen A., Juneja, Vikram R., Manguso, Robert T., LaFleur, Martin W., Collins, Natalie, Haining, W. Nicholas, Freeman, Gordon J., Sharpe, Arlene H.

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NON-AQUEOUS ELECTRODEPOSITABLE CATIONIC DISPERSIONS von MCGUIRE, KATHLEEN A, CHRISTENSON, ROGER M, HANSEN, CHARLES M

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A METHOD OF ELECTRODEPOSITING NON-AQUEOUS CATIONIC DISPERSIONS AND ARTICLES PRODUCED THEREBY von CHRISTENSON, ROGER M, MCGUIRE, KATHLEEN A, HANSEN, CHARLES M

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Ectomycorrhizal-dominated boreal and tropical forests have distinct fungal communities, but analogous spatial patterns across soil horizons von McGuire, Krista L, Allison, Steven D, Fierer, Noah, Treseder, Kathleen K

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Microbial communities and their relevance for ecosystem models: Decomposition as a case study von McGuire, Krista L., Treseder, Kathleen K.

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Functional diversity in resource use by fungi von McGuire, Krista L., Bent, Elizabeth, Borneman, James, Majumder, Arundhati, Allison, Steven D., Treseder, Kathleen K.

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Adding Fuel to the Fire? Examining Exposure to Potentially Stressful or Traumatic Events Before and During the COVID-19 Pandemic in Low-Income, Black Families von McGuire, Austen B., Jackson, Yo, McDonald, Jennifer

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