Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian Carcinoma von Tamura, Naoka, Shaikh, Nadeem, Muliaditan, Daniel, Soliman, Tanya N, McGuinness, Jennifer R, Maniati, Eleni, Moralli, Daniela, Durin, Mary-Anne, Green, Catherine M, Balkwill, Frances R, Wang, Jun, Curtius, Kit, McClelland, Sarah E

Volltext

Subthreshold Nanosecond Laser Intervention in Age-Related Macular Degeneration: The LEAD Randomized Controlled Clinical Trial von Guymer, Robyn H, Wu, Zhichao, Hodgson, Lauren A B, Caruso, Emily, Brassington, Kate H, Tindill, Nicole, Aung, Khin Zaw, McGuinness, Myra B, Fletcher, Erica L, Chen, Fred K, Chakravarthy, Usha, Arnold, Jennifer J, Heriot, Wilson J, Durkin, Shane R, Lek, Jia Jia, Harper, Colin A, Wickremasinghe, Sanjeewa S, Sandhu, Sukhpal S, Baglin, Elizabeth K, Sharangan, Pyrawy, Braat, Sabine, Luu, Chi D

Volltext

Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial von Bradbury, Charlotte A, Lawler, Patrick R, Stanworth, Simon J, McVerry, Bryan J, McQuilten, Zoe, Higgins, Alisa M, Mouncey, Paul R, Al-Beidh, Farah, Rowan, Kathryn M, Berry, Lindsay R, Lorenzi, Elizabeth, Zarychanski, Ryan, Arabi, Yaseen M, Annane, Djillali, Beane, Abi, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bihari, Shailesh, Bonten, Marc J. M, Brunkhorst, Frank M, Buzgau, Adrian, Buxton, Meredith, Carrier, Marc, Cheng, Allen C, Cove, Matthew, Detry, Michelle A, Estcourt, Lise J, Fitzgerald, Mark, Girard, Timothy D, Goligher, Ewan C, Goossens, Herman, Haniffa, Rashan, Hills, Thomas, Huang, David T, Horvat, Christopher M, Hunt, Beverley J, Ichihara, Nao, Lamontagne, Francois, Leavis, Helen L, Linstrum, Kelsey M, Litton, Edward, Marshall, John C, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, Middeldorp, Saskia, Montgomery, Stephanie K, Morpeth, Susan C, Murthy, Srinivas, Neal, Matthew D, Nichol, Alistair D, Parke, Rachael L, Parker, Jane C, Reyes, Luis F, Saito, Hiroki, Santos, Marlene S, Saunders, Christina T, Serpa-Neto, Ary, Seymour, Christopher W, Shankar-Hari, Manu, Singh, Vanessa, Tolppa, Timo, Turgeon, Alexis F, Turner, Anne M, van de Veerdonk, Frank L, Green, Cameron, Lewis, Roger J, Angus, Derek C, McArthur, Colin J, Berry, Scott, Derde, Lennie P. G, Webb, Steve A, Gordon, Anthony C

Volltext

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 von Goligher, Ewan C, Bradbury, Charlotte A, McVerry, Bryan J, Lawler, Patrick R, Berger, Jeffrey S, Gong, Michelle N, Carrier, Marc, Reynolds, Harmony R, Kumar, Anand, Turgeon, Alexis F, Kornblith, Lucy Z, Kahn, Susan R, Marshall, John C, Kim, Keri S, Houston, Brett L, Derde, Lennie P G, Cushman, Mary, Tritschler, Tobias, Angus, Derek C, Godoy, Lucas C, McQuilten, Zoe, Kirwan, Bridget-Anne, Farkouh, Michael E, Brooks, Maria M, Lewis, Roger J, Berry, Lindsay R, Lorenzi, Elizabeth, Gordon, Anthony C, Ahuja, Tania, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Contreras, Aira, Costantini, Todd W, de Brouwer, Sophie, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Eng, Heather F, Escobedo, Jorge, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Froess, Joshua D, Fu, Zhuxuan, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, Girard, Timothy D, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Haniffa, Rashan, Hegde, Sheila M, Hendrickson, Carolyn M, Higgins, Alisa M, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Huang, David T, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Kutcher, Matthew E, Laffan, Michael A, Lamontagne, Francois, Le Gal, Grégoire

Volltext

Autonomic dysfunction is a major feature of cerebellar ataxia, neuropathy, vestibular areflexia 'CANVAS' syndrome von WU, Teddy Y, TAYLOR, Jennifer M, ANDERSON, Neil E, SNOW, Barry J, ANDERSON, Tim J, PAERMENTIER, Laura A. F, CUTFIELD, Nick J, CHANCELLOR, Andrew M, MOSSMAN, Stuart S, ROXBURGH, Richard H, KILFOYLE, Dean H, SMITH, Andrew D, MCGUINNESS, Ben J, SIMPSON, Mark P, WALKER, Elizabeth B, BERGIN, Peter S, CLELAND, James C, HUTCHINSON, David O

Volltext

Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial von Estcourt, Lise J, Turgeon, Alexis F, McQuilten, Zoe K, McVerry, Bryan J, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Arnold, Donald M, Beane, Abigail, Bégin, Philippe, van Bentum-Puijk, Wilma, Berry, Lindsay R, Bhimani, Zahra, Birchall, Janet E, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Buxton, Meredith, Callum, Jeannie L, Chassé, Michaël, Cheng, Allen C, Cove, Matthew E, Daly, James, Derde, Lennie, Detry, Michelle A, De Jong, Menno, Evans, Amy, Fergusson, Dean A, Fish, Matthew, Fitzgerald, Mark, Foley, Claire, Goossens, Herman, Gordon, Anthony C, Gosbell, Iain B, Green, Cameron, Haniffa, Rashan, Harvala, Heli, Higgins, Alisa M, Hills, Thomas E, Hoad, Veronica C, Horvat, Christopher, Huang, David T, Hudson, Cara L, Ichihara, Nao, Laing, Emma, Lamikanra, Abigail A, Lamontagne, François, Lawler, Patrick R, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, MacLennan, Sheila, Marshall, John, McAuley, Daniel F, McDyer, John F, McGlothlin, Anna, McGuinness, Shay, Miflin, Gail, Montgomery, Stephanie, Mouncey, Paul R, Murthy, Srinivas, Nichol, Alistair, Parke, Rachael, Parker, Jane C, Priddee, Nicole, Purcell, Damian F. J, Reyes, Luis F, Richardson, Peter, Robitaille, Nancy, Rowan, Kathryn M, Rynne, Jennifer, Saito, Hiroki, Santos, Marlene, Saunders, Christina T, Serpa Neto, Ary, Seymour, Christopher W, Silversides, Jon A, Tinmouth, Alan A, Triulzi, Darrell J, Turner, Anne M, van de Veerdonk, Frank, Walsh, Timothy S, Wood, Erica M, Berry, Scott, Lewis, Roger J, Menon, David K, McArthur, Colin, Zarychanski, Ryan, Angus, Derek C, Webb, Steve A, Roberts, David J, Shankar-Hari, Manu

Volltext

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries von Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.

Volltext

Prospective Longitudinal Evaluation of Nascent Geographic Atrophy in Age-Related Macular Degeneration von Wu, Zhichao, Luu, Chi D., Hodgson, Lauren A.B., Caruso, Emily, Tindill, Nicole, Aung, Khin Zaw, McGuinness, Myra B., Makeyeva, Galina, Chen, Fred K., Chakravarthy, Usha, Arnold, Jennifer J., Heriot, Wilson J., Durkin, Shane R., Guymer, Robyn H.

Volltext

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial von Higgins, Alisa M, Berry, Lindsay R, Lorenzi, Elizabeth, Murthy, Srinivas, McQuilten, Zoe, Mouncey, Paul R, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Beane, Abi, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Burrell, Aiden, Buzgau, Adrian, Buxton, Meredith, Charles, Walton N, Cove, Matthew, Detry, Michelle A, Estcourt, Lise J, Fagbodun, Elizabeth O, Fitzgerald, Mark, Girard, Timothy D, Goligher, Ewan C, Goossens, Herman, Haniffa, Rashan, Hills, Thomas, Horvat, Christopher M, Huang, David T, Ichihara, Nao, Lamontagne, Francois, Marshall, John C, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McVerry, Bryan J, Neal, Matthew D, Nichol, Alistair D, Parke, Rachael L, Parker, Jane C, Parry-Billings, Karen, Peters, Sam E. C, Reyes, Luis F, Rowan, Kathryn M, Saito, Hiroki, Santos, Marlene S, Saunders, Christina T, Serpa-Neto, Ary, Seymour, Christopher W, Shankar-Hari, Manu, Stronach, Lucy M, Turgeon, Alexis F, Turner, Anne M, van de Veerdonk, Frank L, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, McArthur, Colin J, Berry, Scott, Derde, Lennie P. G, Gordon, Anthony C, Webb, Steve A, Lawler, Patrick R

Volltext

Discerning autotrophy, mixotrophy and heterotrophy in marine TACK archaea from the North Atlantic von Seyler, Lauren M, McGuinness, Lora R, Gilbert, Jack A, Biddle, Jennifer F, Gong, Donglai, Kerkhof, Lee J

Volltext

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19: A Randomized Clinic... von Lawler, Patrick R, Derde, Lennie P. G, van de Veerdonk, Frank L, McVerry, Bryan J, Huang, David T, Berry, Lindsay R, Lorenzi, Elizabeth, van Kimmenade, Roland, Gommans, Frank, Vaduganathan, Muthiah, Leaf, David E, Baron, Rebecca M, Kim, Edy Y, Frankfurter, Claudia, Epelman¸, Slava, Kwan, Yvonne, Grieve, Richard, O'Neill, Stephen, Sadique, Zia, Puskarich, Michael, Marshall, John C, Higgins, Alisa M, Mouncey, Paul R, Rowan, Kathryn M, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Au, Carly, Beane, Abi, van Bentum-Puijk, Wilma, Bonten, Marc J. M, Bradbury, Charlotte A, Brunkhorst, Frank M, Burrell, Aidan, Buzgau, Adrian, Buxton, Meredith, Cecconi, Maurizio, Cheng, Allen C, Cove, Matthew, Detry, Michelle A, Estcourt, Lise J, Ezekowitz, Justin, Fitzgerald, Mark, Gattas, David, Godoy, Lucas C, Goossens, Herman, Haniffa, Rashan, Harrison, David A, Hills, Thomas, Horvat, Christopher M, Ichihara, Nao, Lamontagne, Francois, Linstrum, Kelsey M, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McQuilten, Zoe, Murthy, Srinivas, Nichol, Alistair D, Owen, David R. J, Parke, Rachael L, Parker, Jane C, Pollock, Katrina M, Reyes, Luis Felipe, Saito, Hiroki, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Singh, Vanessa, Turgeon, Alexis F, Turner, Anne M, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, Berry, Scott, Gordon, Anthony C, McArthur, Colin J, Webb, Steve A

Volltext

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials von Adhikari, Neill K. J, Hashmi, Madiha, Tirupakuzhi Vijayaraghavan, Bharath Kumar, Haniffa, Rashan, Beane, Abi, Webb, Steve A, Angus, Derek C, Gordon, Anthony C, Cook, Deborah J, Guyatt, Gordon H, Berry, Lindsay R, Lorenzi, Elizabeth, Mouncey, Paul R, Au, Carly, Pinto, Ruxandra, Ménard, Julie, Sprague, Sheila, Masse, Marie-Hélène, Huang, David T, Heyland, Daren K, Nichol, Alistair D, McArthur, Colin J, de Man, Angelique, Al-Beidh, Farah, Annane, Djillali, Anstey, Matthew, Arabi, Yaseen M, Battista, Marie-Claude, Berry, Scott, Bhimani, Zahra, Bonten, Marc J. M, Bradbury, Charlotte A, Brant, Emily B, Brunkhorst, Frank M, Burrell, Aidan, Buxton, Meredith, Cecconi, Maurizio, Cheng, Allen C, Cohen, Dian, Cove, Matthew E, Day, Andrew G, Derde, Lennie P. G, Detry, Michelle A, Estcourt, Lise J, Fagbodun, Elizabeth O, Fitzgerald, Mark, Goossens, Herman, Green, Cameron, Higgins, Alisa M, Hills, Thomas E, Horvat, Christopher, Ichihara, Nao, Jayakumar, Devachandran, Kanji, Salmaan, Khoso, Muhammad Nasir, Lawler, Patrick R, Lewis, Roger J, Litton, Edward, Marshall, John C, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McQuilten, Zoe K, McVerry, Bryan J, Murthy, Srinivas, Parke, Rachael L, Parker, Jane C, Reyes, Luis Felipe, Rowan, Kathryn M, Saito, Hiroki, Salahuddin, Nawal, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Tolppa, Timo, Trapani, Tony, Turgeon, Alexis F, Turner, Anne M, Udy, Andrew A, van de Veerdonk, Frank L, Zarychanski, Ryan, Lamontagne, François

Volltext

The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis von Fiorito, Giovanni, Pedron, Sara, Ochoa-Rosales, Carolina, McCrory, Cathal, Polidoro, Silvia, Zhang, Yan, Dugué, Pierre-Antoine, Ratliff, Scott, Zhao, Wei N, McKay, Gareth J, Costa, Giuseppe, Solinas, Maria Giuliana, Harris, Kathleen Mullan, Tumino, Rosario, Grioni, Sara, Ricceri, Fulvio, Panico, Salvatore, Brenner, Hermann, Schwettmann, Lars, Waldenberger, Melanie, Matias-Garcia, Pamela R, Peters, Annette, Hodge, Allison, Giles, Graham G, Schmitz, Lauren L, Levine, Morgan, Smith, Jennifer A, Liu, Yongmei, Kee, Frank, Young, Ian S, McGuinness, Bernadette, McKnight, Amy Jayne, van Meurs, Joyce, Voortman, Trudy, Kenny, Rose A, Vineis, Paolo, Carmeli, Cristian

Volltext

Genome-wide association study of Alzheimer's disease with psychotic symptoms von Hollingworth, P, Sweet, R, Sims, R, Harold, D, Russo, G, Abraham, R, Stretton, A, Jones, N, Gerrish, A, Chapman, J, Ivanov, D, Moskvina, V, Lovestone, S, Priotsi, P, Lupton, M, Brayne, C, Gill, M, Lawlor, B, Lynch, A, Craig, D, McGuinness, B, Johnston, J, Holmes, C, Livingston, G, Bass, N J, Gurling, H, McQuillin, A, Holmans, P, Jones, L, Devlin, B, Klei, L, Barmada, M M, Demirci, F Y, DeKosky, S T, Lopez, O L, Passmore, P, Owen, M J, O'Donovan, M C, Mayeux, R, Kamboh, M I, Williams, J

Volltext

Associations with photoreceptor thickness measures in the UK Biobank von Chua, Sharon Y. L., Dhillon, Baljean, Aslam, Tariq, Balaskas, Konstantinos, Yang, Qi, Keane, Pearse A., Tufail, Adnan, Reisman, Charles, Foster, Paul J., Patel, Praveen J.

Volltext

Suitability of UK Biobank Retinal Images for Automatic Analysis of Morphometric Properties of the Vasculature von MacGillivray, Thomas J, Cameron, James R, Zhang, Qiuli, El-Medany, Ahmed, Mulholland, Carl, Sheng, Ziyan, Dhillon, Bal, Doubal, Fergus N, Foster, Paul J, Trucco, Emmanuel, Sudlow, Cathie

Volltext

Cohort profile: design and methods in the eye and vision consortium of UK Biobank von Chua, Sharon Yu Lin, Thomas, Dhanes, Allen, Naomi, Lotery, Andrew, Desai, Parul, Patel, Praveen, Muthy, Zaynah, Sudlow, Cathie, Peto, Tunde, Khaw, Peng Tee, Foster, Paul J

Volltext

Secondary and Exploratory Outcomes of the Subthreshold Nanosecond Laser Intervention Randomized Trial in Age-Related Macular Degeneration: A LEAD Study Report von Wu, Zhichao, Luu, Chi D., Hodgson, Lauren A.B., Caruso, Emily, Brassington, Kate H., Tindill, Nicole, Aung, Khin Zaw, Harper, Colin A., Wickremasinghe, Sanjeewa S., Sandhu, Sukhpal S., McGuinness, Myra B., Chen, Fred K., Chakravarthy, Usha, Arnold, Jennifer J., Heriot, Wilson J., Durkin, Shane R., Wintergerst, Maximilian W.M., Gorgi Zadeh, Shekoufeh, Schultz, Thomas, Finger, Robert P., Cohn, Amy C., Baglin, Elizabeth K., Sharangan, Pyrawy, Guymer, Robyn H.

Volltext

Induction of labour care in the UK: A cross-sectional survey of maternity units von Taylor, Beck, Cross-Sudworth, Fiona, Rimmer, Michael, Quinn, Laura, Morris, R Katie, Johnston, Tracey, Morad, Sharon, Davidson, Louisa, Kenyon, Sara

Volltext

Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease von Chaudhury, Sultan, Patel, Tulsi, Barber, Imelda S., Guetta-Baranes, Tamar, Brookes, Keeley J., Chappell, Sally, Turton, James, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Hardy, John, Mann, David, Passmore, Peter, Craig, David, Johnston, Janet, McGuinness, Bernadette, Todd, Stephen, Heun, Reinhard, Kölsch, Heike, Kehoe, Patrick G., Vardy, Emma R.L.C., Hooper, Nigel M., Pickering-Brown, Stuart, Snowden, Julie, Richardson, Anna, Jones, Matthew, Neary, David, Harris, Jennifer, Lowe, James, Smith, A. David, Wilcock, Gordon, Warden, Donald, Holmes, Clive, Morgan, Kevin

Volltext