Mode of action of bullatacin: A potent antitumor and pesticidal Annonaceous acetogenin von Ahammadsahib, K.I., Hollingworth, R.M., McGovren, J.P., Hui, Y.-H, McLaughlin, J.L.

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Studies of the efficacy and pharmacology of irinotecan against human colon tumor xenograft models von Zamboni, W C, Stewart, C F, Cheshire, P J, Richmond, L B, Hanna, S K, Luo, X, Poquette, C, McGovren, J P, Houghton, J A, Houghton, P J

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Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue von Li, L H, DeKoning, T F, Kelly, R C, Krueger, W C, McGovren, J P, Padbury, G E, Petzold, G L, Wallace, T L, Ouding, R J, Prairie, M D

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Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065 von Warpehoski, M. A, Gebhard, I, Kelly, R. C, Krueger, W. C, Li, L. H, McGovren, J. P, Prairie, M. D, Wicnienski, N, Wierenga, W

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Preclinical antitumor activity of bizelesin in mice von CARTER, C. A, WAUD, W. R, LI, L. H, DEKONING, T. F, MCGOVREN, J. P, PLOWMAN, J

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Molecular basis for sequence-specific DNA alkylation by CC-1065 von Hurley, Laurence H, Lee, Chong Soon, McGovren, J. Patrick, Warpehoski, Martha A, Mitchell, Mark A, Kelly, Robert C, Aristoff, Paul A

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Lethality, DNA alkylation, and cell cycle effects of adozelesin (U-73975) on rodent and human cells von BHUYAN, B. K, SMITH, K. S, ADAMS, E. G, PETZOLD, G. L, MCGOVREN, J. P

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Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065 von LI, L. H, KELLY, R. C, WARPEHOSKI, M. A, MCGOVREN, J. P, GEBHARD, I, DEKONING, T. F

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THE CHEMISTRY, MECHANISM OF ACTION AND BIOLOGICAL PROPERTIES OF CC-1065, A POTENT ANTITUMOR ANTIBIOTIC von REYNOLDS, VINCENT L., MCGOVREN, J. PATRICK, HURLEY, LAURENCE H.

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12,13-Isotaxanes:  Synthesis of New Potent Analogs and X-ray Crystallographic Confirmation of Structure von Johnson, Roy A, Dobrowolski, Paul J, Nidy, Eldon G, Gebhard, Ilse, Qualls, Samuel J, Wicnienski, Nancy A, Kelly, Robert C, Pitts, Thomas W, Lopes, Narima M, DeKoning, Thomas F, Mattern, Sally J, Weed, Sheldon D, McGovren, J. Patrick, Chidester, Constance G

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PRELIMINARY TOXICITY STUDIES WITH THE DNA-BINDING ANTIBIOTIC, CC-1065 von MCGOVREN, J. PATRICK, CLARKE, GEORGE L., PRATT, EVELYN A., DEKONING, THOMAS F.

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Sequence specificity of DNA alkylation by the unnatural enantiomer of CC-1065 and its synthetic analogs von Hurley, Laurence H, Warpehoski, Martha A, Lee, Chong Soon, McGovren, J. Patrick, Scahill, Terrence A, Kelly, Robert C, Mitchell, Mark A, Wicnienski, Nancy A, Gebhard, Ilse

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Relationship of Baseline Serum Bilirubin to Efficacy and Toxicity of Single-Agent Irinotecan in Patients With Metastatic Colorectal Cancer von MEYERHARDT, Jeffrey A, KWOK, Ambrose, RATAIN, Mark J, MCGOVREN, J. Patrick, FUCHS, Charles S

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Pharmacokinetics and systemic bioavailability of menogaril, and anthracycline antitumor agent, in the mouse, dog, and monkey von ADAMS, W. J, MCGOVREN, J. P, DALM, E. A, BREWER, J. E, HOSLEY, J. D

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Quantitation of anthracycline antitumor agent menogarol in plasma using liquid chromatography with fluorescence detection von McGovren, J. Patrick, Hamilton, Ramon D, Adams, Wade J, Pratt, Evelyn A

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Didemnins: Antiviral and Antitumor Depsipeptides from a Caribbean Tunicate von Rinehart, Kenneth L., Gloer, James B., Hughes, Robert G., Renis, Harold E., McGovren, J. Patrick, Swynenberg, Everett B., Stringfellow, Dale A., Kuentzel, Sandra L., Li H. Li

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Quantitation of antitumor agent acivicin in plasma by gas chromatography/mass spectrometry von McGovren, J. Patrick, Williams, Marta G, Robins, Russell H, Roach, Braden L

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Phase I and pharmacokinetic study of edotecarin, a novel topoisomerase I inhibitor, administered once every 3 weeks in patients with solid tumors von YAMADA, Yasuhide, TAMURA, Tomohide, MCGOVREN, J. Patrick, NATSUMEDA, Yutaka, YAMAMOTO, Noboru, SHIMOYAMA, Tatsu, UEDA, Yutaka, MURAKAMI, Haruyasu, KUSABA, Hitoshi, KAMIYA, Yoshikazu, SAKA, Hideo, TANIGAWARA, Yusuke

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Biologically active peptides and their mass spectra von Rinehart, K. L., Cook, J. C., Pandey, R. C., Gaudioso, L. A., Meng, Hsi, Moore, M. L., Gloer, J. B., Wilson, G. R., Gutowsky, R. E., Zierath, P. D., Shield, L. S., Li, L. H., Renis, H. E., McGovren, J. P., Canonico, P. G.

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Prevention of central nervous system toxicity of the antitumor antibiotic acivicin by concomitant infusion of an amino acid mixture von Williams, M G, Earhart, R H, Bailey, H, McGovren, J P

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