IL-15 induces strong but short-lived tumor-infiltrating CD8 T cell responses through the regulation of Tim-3 in breast cancer von Heon, Elise K., Wulan, Hasi, Macdonald, Loch P., Malek, Adel O., Braunstein, Glenn H., Eaves, Connie G., Schattner, Mark D., Allen, Peter M., Alexander, Michael O., Hawkins, Cynthia A., McGovern, Dermot W., Freeman, Richard L., Amir, Eitan P., Huse, Jason D., Zaltzman, Jeffrey S., Kauff, Noah P., Meyers, Paul G., Gleason, Michelle H., Overholtzer, Michael G., Wiseman, Sam S., Streutker, Catherine D., Asa, Sylvia W., McAlindon, Timothy P., Newcomb, Polly O., Sorensen, Poul M., Press, Oliver A.

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Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease von Chu, Hiutung, Khosravi, Arya, Kusumawardhani, Indah P., Kwon, Alice H. K., Vasconcelos, Anilton C., Cunha, Larissa D., Mayer, Anne E., Shen, Yue, Wu, Wei-Li, Kambal, Amal, Targan, Stephan R., Xavier, Ramnik J., Ernst, Peter B., Green, Douglas R., McGovern, Dermot P. B., Virgin, Herbert W., Mazmanian, Sarkis K.

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Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans von Ha, Connie W.Y., Martin, Anthony, Sepich-Poore, Gregory D., Shi, Baochen, Wang, Yizhou, Gouin, Kenneth, Humphrey, Gregory, Sanders, Karenina, Ratnayake, Yasiru, Chan, Kelvin S.L., Hendrick, Gustaf, Caldera, J.R., Arias, Christian, Moskowitz, Jacob E., Ho Sui, Shannan J., Yang, Shaohong, Underhill, David, Brady, Matthew J., Knott, Simon, Kaihara, Kelly, Steinbaugh, Michael J., Li, Huiying, McGovern, Dermot P.B., Knight, Rob, Fleshner, Phillip, Devkota, Suzanne

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Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease von Norman, Jason M., Handley, Scott A., Baldridge, Megan T., Droit, Lindsay, Liu, Catherine Y., Keller, Brian C., Kambal, Amal, Monaco, Cynthia L., Zhao, Guoyan, Fleshner, Phillip, Stappenbeck, Thaddeus S., McGovern, Dermot P.B., Keshavarzian, Ali, Mutlu, Ece A., Sauk, Jenny, Gevers, Dirk, Xavier, Ramnik J., Wang, David, Parkes, Miles, Virgin, Herbert W.

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Dynamics of metatranscription in the inflammatory bowel disease gut microbiome von Schirmer, Melanie, Franzosa, Eric A., Lloyd-Price, Jason, McIver, Lauren J., Schwager, Randall, Poon, Tiffany W., Ananthakrishnan, Ashwin N., Andrews, Elizabeth, Barron, Gildardo, Lake, Kathleen, Prasad, Mahadev, Sauk, Jenny, Stevens, Betsy, Wilson, Robin G., Braun, Jonathan, Denson, Lee A., Kugathasan, Subra, McGovern, Dermot P. B., Vlamakis, Hera, Xavier, Ramnik J., Huttenhower, Curtis

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T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling von Marchelletta, Ronald R., Krishnan, Moorthy, Spalinger, Marianne R., Placone, Taylaur W., Alvarez, Rocio, Sayoc-Becerra, Anica, Canale, Vinicius, Shawki, Ali, Park, Young Su, Bernts, Lucas H. P., Myers, Stephen, Tremblay, Michel L., Barrett, Kim E., Krystofiak, Evan, Kachar, Bechara, McGovern, Dermot P. B., Weber, Christopher R., Hanson, Elaine M., Eckmann, Lars, McCole, Declan F.

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Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease von Rivas, Manuel A, Daly, Mark J, Beaudoin, Mélissa, Gardet, Agnes, Stevens, Christine, Sharma, Yashoda, Zhang, Clarence K, Boucher, Gabrielle, Ripke, Stephan, Ellinghaus, David, Burtt, Noel, Fennell, Tim, Kirby, Andrew, Latiano, Anna, Goyette, Philippe, Green, Todd, Halfvarson, Jonas, Haritunians, Talin, Korn, Joshua M, Kuruvilla, Finny, Lagacé, Caroline, Neale, Benjamin, Lo, Ken Sin, Schumm, Phil, Törkvist, Leif, Dubinsky, Marla C, Brant, Steven R, Silverberg, Mark S, Duerr, Richard H, Altshuler, David, Gabriel, Stacey, Lettre, Guillaume, Franke, Andre, D'Amato, Mauro, McGovern, Dermot P B, Cho, Judy H, Rioux, John D, Xavier, Ramnik J

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Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases von Lloyd-Price, Jason, Arze, Cesar, Ananthakrishnan, Ashwin N., Schirmer, Melanie, Avila-Pacheco, Julian, Poon, Tiffany W., Andrews, Elizabeth, Ajami, Nadim J., Bonham, Kevin S., Brislawn, Colin J., Casero, David, Courtney, Holly, Gonzalez, Antonio, Graeber, Thomas G., Hall, A. Brantley, Lake, Kathleen, Landers, Carol J., Mallick, Himel, Plichta, Damian R., Prasad, Mahadev, Rahnavard, Gholamali, Sauk, Jenny, Shungin, Dmitry, Vázquez-Baeza, Yoshiki, White, Richard A., Braun, Jonathan, Denson, Lee A., Jansson, Janet K., Knight, Rob, Kugathasan, Subra, McGovern, Dermot P. B., Petrosino, Joseph F., Stappenbeck, Thaddeus S., Winter, Harland S., Clish, Clary B., Franzosa, Eric A., Vlamakis, Hera, Xavier, Ramnik J., Huttenhower, Curtis

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Molecular classification of Crohn's disease reveals two clinically relevant subtypes von Weiser, Matthew, Simon, Jeremy M, Kochar, Bharati, Tovar, Adelaide, Israel, Jennifer W, Robinson, Adam, Gipson, Gregory R, Schaner, Matthew S, Herfarth, Hans H, Sartor, R Balfour, McGovern, Dermot P B, Rahbar, Reza, Sadiq, Timothy S, Koruda, Mark J, Furey, Terrence S, Sheikh, Shehzad Z

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Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases von Šimurina, Mirna, de Haan, Noortje, Vučković, Frano, Kennedy, Nicholas A., Štambuk, Jerko, Falck, David, Trbojević-Akmačić, Irena, Clerc, Florent, Razdorov, Genadij, Khon, Anna, Latiano, Anna, D'Incà, Renata, Danese, Silvio, Targan, Stephan, Landers, Carol, Dubinsky, Marla, Campbell, Harry, Zoldoš, Vlatka, Permberton, Iain K., Kolarich, Daniel, Fernandes, Daryl L., Theorodorou, Evropi, Merrick, Victoria, Spencer, Daniel I., Gardner, Richard A., Doran, Ray, Shubhakar, Archana, Boyapati, Ray, Rudan, Igor, Lionetti, Paolo, Krištić, Jasminka, Novokmet, Mislav, Pučić-Baković, Maja, Gornik, Olga, Andriulli, Angelo, Cantoro, Laura, Sturniolo, Giancarlo, Fiorino, Gionata, Manetti, Natalia, Arnott, Ian D., Noble, Colin L., Lees, Charlie W., Shand, Alan G., Ho, Gwo-Tzer, Dunlop, Malcolm G., Murphy, Lee, Gibson, Jude, Evenden, Louise, Wrobel, Nicola, Gilchrist, Tamara, Fawkes, Angie, Kammeijer, Guinevere S.M., Vojta, Aleksandar, Samaržija, Ivana, Markulin, Dora, Klasić, Marija, Dobrinić, Paula, Aulchenko, Yurii, van den Heuve, Tim, Jonkers, Daisy, Pierik, Marieke, McGovern, Dermot P.B., Annese, Vito, Wuhrer, Manfred, Lauc, Gordan

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Trans-ancestry, Bayesian meta-analysis discovers 20 novel risk loci for inflammatory bowel disease in an African American, East Asian and European cohort von Cordero, Roberto Y, Cordero, Jennifer B, Stiemke, Andrew B, Datta, Lisa W, Buyske, Steven, Kugathasan, Subra, McGovern, Dermot P B, Brant, Steven R, Simpson, Claire L

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Mutations in Tetratricopeptide Repeat Domain 7A Result in a Severe Form of Very Early Onset Inflammatory Bowel Disease von Avitzur, Yaron, Guo, Conghui, Mastropaolo, Lucas A, Bahrami, Ehsan, Chen, Hannah, Zhao, Zhen, Elkadri, Abdul, Dhillon, Sandeep, Murchie, Ryan, Fattouh, Ramzi, Huynh, Hien, Walker, Jennifer L, Wales, Paul W, Cutz, Ernest, Kakuta, Yoichi, Dudley, Joel, Kammermeier, Jochen, Powrie, Fiona, Shah, Neil, Walz, Christoph, Nathrath, Michaela, Kotlarz, Daniel, Puchaka, Jacek, Krieger, Jonathan R, Racek, Tomas, Kirchner, Thomas, Walters, Thomas D, Brumell, John H, Griffiths, Anne M, Rezaei, Nima, Rashtian, Parisa, Najafi, Mehri, Monajemzadeh, Maryam, Pelsue, Stephen, McGovern, Dermot P.B, Uhlig, Holm H, Schadt, Eric, Klein, Christoph, Snapper, Scott B, Muise, Aleixo M

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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients von Wu, Yiming, Gettler, Kyle, Kars, Meltem Ece, Giri, Mamta, Li, Dalin, Bayrak, Cigdem Sevim, Zhang, Peng, Jain, Aayushee, Maffucci, Patrick, Sabic, Ksenija, Van Vleck, Tielman, Nadkarni, Girish, Denson, Lee A., Ostrer, Harry, Levine, Adam P., Schiff, Elena R., Segal, Anthony W., Kugathasan, Subra, Stenson, Peter D., Cooper, David N., Philip Schumm, L., Snapper, Scott, Daly, Mark J., Haritunians, Talin, Duerr, Richard H., Silverberg, Mark S., Rioux, John D., Brant, Steven R., McGovern, Dermot P. B., Cho, Judy H., Itan, Yuval

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Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease von Brant, Steven R, Okou, David T, Simpson, Claire L, Cutler, David J, Haritunians, Talin, Bradfield, Jonathan P, Chopra, Pankaj, Prince, Jarod, Begum, Ferdouse, Kumar, Archana, Huang, Chengrui, Venkateswaran, Suresh, Datta, Lisa W, Wei, Zhi, Thomas, Kelly, Herrinton, Lisa J, Klapproth, Jan-Micheal A, Quiros, Antonio J, Seminerio, Jenifer, Liu, Zhenqiu, Alexander, Jonathan S, Baldassano, Robert N, Dudley-Brown, Sharon, Cross, Raymond K, Dassopoulos, Themistocles, Denson, Lee A, Dhere, Tanvi A, Dryden, Gerald W, Hanson, John S, Hou, Jason K, Hussain, Sunny Z, Hyams, Jeffrey S, Isaacs, Kim L, Kader, Howard, Kappelman, Michael D, Katz, Jeffry, Kellermayer, Richard, Kirschner, Barbara S, Kuemmerle, John F, Kwon, John H, Lazarev, Mark, Li, Ellen, Mack, David, Mannon, Peter, Moulton, Dedrick E, Newberry, Rodney D, Osuntokun, Bankole O, Patel, Ashish S, Saeed, Shehzad A, Targan, Stephan R, Valentine, John F, Wang, Ming-Hsi, Zonca, Martin, Rioux, John D, Duerr, Richard H, Silverberg, Mark S, Cho, Judy H, Hakonarson, Hakon, Zwick, Michael E, McGovern, Dermot P.B, Kugathasan, Subra

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Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab von Kennedy, Nicholas A, Goodhand, James R, Bewshea, Claire, Nice, Rachel, Chee, Desmond, Lin, Simeng, Chanchlani, Neil, Butterworth, Jeffrey, Cooney, Rachel, Croft, Nicholas M, Hart, Ailsa L, Irving, Peter M, Kok, Klaartje B, Lamb, Christopher A, Limdi, Jimmy K, Macdonald, Jonathan, McGovern, Dermot PB, Mehta, Shameer J, Murray, Charles D, Patel, Kamal V, Pollok, Richard CG, Raine, Timothy, Russell, Richard K, Selinger, Christian P, Smith, Philip J, Bowden, Jack, McDonald, Timothy J, Lees, Charlie W, Sebastian, Shaji, Powell, Nicholas, Ahmad, Tariq

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Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease von Somineni, Hari K., Nagpal, Sini, Venkateswaran, Suresh, Cutler, David J., Okou, David T., Haritunians, Talin, Simpson, Claire L., Begum, Ferdouse, Datta, Lisa W., Quiros, Antonio J., Seminerio, Jenifer, Mengesha, Emebet, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Iskandar, Heba, Dryden, Gerald W., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kuemmerle, John F., Lazarev, Mark, Li, Ellen, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Patel, Ashish S., Pekow, Joel, Saeed, Shehzad A., Valentine, John F., Wang, Ming-Hsi, McCauley, Jacob L., Abreu, Maria T., Jester, Traci, Molle-Rios, Zarela, Palle, Sirish, Scherl, Ellen J., Kwon, John, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Zwick, Michael E., Stevens, Christine, Daly, Mark J., Cho, Judy H., Gibson, Greg, McGovern, Dermot P.B., Brant, Steven R., Kugathasan, Subra

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A screen of Crohn’s disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells von Chang, Yu-Ling, Rossetti, Maura, Vlamakis, Hera, Casero, David, Sunga, Gemalene, Harre, Nicholas, Miller, Shelley, Humphries, Romney, Stappenbeck, Thaddeus, Simpson, Kenneth W., Sartor, R. Balfour, Wu, Gary, Lewis, James, Bushman, Frederic, McGovern, Dermot P. B., Salzman, Nita, Borneman, James, Xavier, Ramnik, Huttenhower, Curtis, Braun, Jonathan

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Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility von Stevens, Christine R., Venkataraman, Guhan R., Avila, Brandon, Abreu, Maria T., Ahmad, Tariq, Allez, Matthieu, Ananthakrishnan, Ashwin N., Barrett, Jeffrey C., Barzilai, Nir, Beaugerie, Laurent, Beecham, Ashley, Bokemeyer, Bernd, Chan, Andrew, Cleynen, Isabelle, Cosnes, Jacques, Cutler, David J., Daly, Allan, Damas, Oriana M., Datta, Lisa W., Dawany, Noor, Devoto, Marcella, Dodge, Sheila, Ellinghaus, Eva, Farkkila, Martti, Faubion, William, Ferreira, Manuel, Gabriel, Stacey B., Ge, Tian, Georges, Michel, Gettler, Kyle, Giri, Mamta, Goyette, Philippe, Graham, Daniel, Hämäläinen, Eija, Haritunians, Talin, Heap, Graham A., Hiltunen, Mikko, Hoeppner, Marc, Horowitz, Julie E., Iyer, Vivek, Kelsen, Judith, Khalili, Hamed, Kirschner, Barbara S., Koskela, Jukka T., Kugathasan, Subra, Kupcinskas, Juozas, Laudes, Matthias, Levine, Adam P., Liefferinckx, Claire, Loescher, Britt-Sabina, Louis, Edouard, Mansfield, John, May, Sandra, McCauley, Jacob L., Mengesha, Emebet, Mni, Myriam, Moayyedi, Paul, Newberry, Rodney D., Okou, David T., Ostrer, Harry, Paquette, Jean, Pekow, Joel, Pierik, Marieke J., Ponsioen, Cyriel Y., Pontikos, Nikolas, Prescott, Natalie, Pulver, Ann E., Rahmouni, Souad, Sands, Bruce, Sartor, R. Balfour, Schiff, Elena R., Schreiber, Stefan, Schumm, L. Philip, Segal, Anthony W., Seksik, Philippe, Sheikh, Shehzad Z., Silverberg, Mark S., Simmons, Alison, Skeiceviciene, Jurgita, Sokol, Harry, Solomonson, Matthew, Somineni, Hari, Sun, Dylan, Targan, Stephan, Turner, Dan, van der Meulen, Andrea E., Vermeire, Séverine, Verstockt, Sare, Voskuil, Michiel D., Duerr, Richard H., Franke, Andre, Brant, Steven R., Cho, Judy, Parkes, Miles, Xavier, Ramnik J., Rivas, Manuel A., Rioux, John D., McGovern, Dermot P. B., Huang, Hailiang, Anderson, Carl A.

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci von Jostins, Luke, Dubinsky, Marla, Baldassano, Robert N, Cho, Judy H, Mathew, Christopher G, Cohen, Albert, Prescott, Natalie J, Barclay, Murray, Annese, Vito, Silverberg, Mark S, Taylor, Kent D, Weersma, Rinse K, Satsangi, Jack, Haritunians, Talin, Roberts, Rebecca, Steinhart, A Hillary, Libioulle, Cecile, Regueiro, Miguel, Stronati, Laura, De Vos, Martine, Sans, Miquel, Anderson, Carl A, Wilson, David, Levine, Arie, Glas, Jürgen, McGovern, Dermot P B, Ellinghaus, David, Daly, Mark J, Laukens, Debby, Proctor, Deborah D, Lawrance, Ian, Raychaudhuri, Soumya, Gearry, Richard, Latiano, Anna, Cottone, Mario, Edwards, Cathryn, Sharma, Yashoda, Duerr, Richard H, Florin, Tim, Louis, Edouard, Rutgeerts, Paul, Ahmad, Tariq, Griffiths, Anne M, Hakonarson, Hakon, Festen, Eleonora M, Schumm, Philip, Sanderson, Jeremy, Franchimont, Denis, Verspaget, Hein W, Barrett, Jeffrey C, Lemann, Marc, Kullak-Ublick, Gerd, Rioux, John D, Newman, William, Stokkers, Pieter C F, Brant, Steven R, Balschun, Tobias, Karban, Amir, Montgomery, Grant W, Brand, Stephan, Kugathasan, Subra, D'Amato, Mauro, Lees, Charlie W, Denson, Ted, Halfvarson, Jonas, Bis, Joshua C, Schreiber, Stefan, D'Inca, Renata, Simms, Lisa A, Bumpstead, Suzanne, Torkvist, Leif, Mowat, Craig, Russell, Richard, Bayless, Theodore M, Seibold, Frank, Vermeire, Severine, Franke, Andre, Lee, James, Green, Todd, Van Gossum, Andre, Colombel, Jean-Frederick, Georges, Michel, Walters, Thomas, Wijmenga, Cisca, Targan, Stephan R, Radford-Smith, Graham L, Guthery, Stephen L, Mansfield, John C, Büning, Carsten, Wang, Kai, Parkes, Miles, Panés, Julián, Phillips, Anne, Rotter, Jerome I, Whiteman, David, Hugot, Jean-Pierre

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HLA-DQA1∗05 Genotype and Immunogenicity to Tumor Necrosis Factor-α Antagonists: A Systematic Review and Meta-analysis von Solitano, Virginia, Facciorusso, Antonio, McGovern, Dermot P.B., Nguyen, Tran, Colman, Ruben J., Zou, Lily, Boland, Brigid S., Syversen, Silje W., Jørgensen, Kristin Kaasen, Ma, Christopher, Armuzzi, Alessandro, Wilson, Aze, Jairath, Vipul, Singh, Siddharth

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