Pyranonaphthoquinone Lactones: A New Class of AKT Selective Kinase Inhibitors Alkylate a Regulatory Loop Cysteine von Salaski, Edward J, Krishnamurthy, Girija, Ding, Wei-Dong, Yu, Ker, Insaf, Shabana S, Eid, Clark, Shim, Jaechul, Levin, Jeremy I, Tabei, Keiko, Toral-Barza, Lourdes, Zhang, Wei-Guo, McDonald, Leonard A, Honores, Erick, Hanna, Cilien, Yamashita, Ayako, Johnson, Bernard, Li, Zhong, Laakso, Leif, Powell, Dennis, Mansour, Tarek S

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Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors von McDonald, Leonard A, Barbieri, Laurel R, Carter, Guy T, Lenoy, Eileen, Lotvin, Jason, Petersen, Peter J, Siegel, Marshall M, Singh, Guy, Williamson, R. Thomas

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Fermentative production of self-toxic fungal secondary metabolites von Singh, Maya P, Leighton, Margaret M, Barbieri, Laurel R, Roll, Deborah M, Urbance, Susan E, Hoshan, Linda, McDonald, Leonard A

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Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines von Toral-Barza, Lourdes, Zhang, Wei-Guo, Huang, Xinyi, McDonald, Leonard A, Salaski, Edward J, Barbieri, Laurel R, Ding, Wei-Dong, Krishnamurthy, Girija, Hu, Yong Bo, Lucas, Judy, Bernan, Valerie S, Cai, Ping, Levin, Jeremy I, Mansour, Tarek S, Gibbons, James J, Abraham, Robert T, Yu, Ker

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Stereoselective Synthesis of an Active Metabolite of the Potent PI3 Kinase Inhibitor PKI-179 von Chen, Zecheng, Venkatesan, Aranapakam M, Dos Santos, Osvaldo, Delos Santos, Efren, Dehnhardt, Christoph M, Ayral-Kaloustian, Semiramis, Ashcroft, Joseph, McDonald, Leonard A, Mansour, Tarek S

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07H239-A, a New Cytotoxic Eremophilane Sesquiterpene from the Marine-Derived Xylariaceous Fungus LL-07H239 von McDonald, Leonard A, Barbieri, Laurel R, Bernan, Valerie S, Janso, Jeffrey, Lassota, Peter, Carter, Guy T

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The Lecanindoles, Nonsteroidal Progestins from the Terrestrial Fungus Verticillium lecanii 6144 von Roll, Deborah M, Barbieri, Laurel R, Bigelis, Ramunas, McDonald, Leonard A, Arias, Daniel A, Chang, Li-Ping, Singh, Maya P, Luckman, Scott W, Berrodin, Thomas J, Yudt, Matthew R

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Namenamicin, a New Enediyne Antitumor Antibiotic from the Marine Ascidian Polysyncraton lithostrotum von McDonald, Leonard A, Capson, Todd L, Krishnamurthy, Girija, Ding, Wei-Dong, Ellestad, George A, Bernan, Valerie S, Maiese, William M, Lassota, Piotr, Kramer, Robert A, Ireland, Chris M

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Depsides isolated from the Sri Lankan lichen Parmotrema sp. exhibit selective Plk1 inhibitory activity von Williams, David E., Loganzo, Frank, Whitney, Lauren, Togias, Jenny, Harrison, Richard, Singh, Maya P., McDonald, Leonard A., Kathirgamanathar, Selvaluxmy, Karunaratne, Veranja, Andersen, Raymond J.

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Fibrosterol Sulfates from the Philippine Sponge Lissodendoryx (Acanthodoryx) fibrosa: Sterol Dimers that Inhibit PKCζ von Whitson, Emily L, Bugni, Tim S, Chockalingam, Priya S, Concepcion, Gisela P, Feng, Xidong, Jin, Guixian, Harper, Mary Kay, Mangalindan, Gina C, McDonald, Leonard A, Ireland, Chris M

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Absolute stereochemistry of the spiroxins von Wang, Tao, Shirota, Osamu, Nakanishi, Koji, Berova, Nina, McDonald, Leonard A, Barbieri, Laurel R, Carter, Guy T

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Tawicyclamides A and B, new cyclic peptides from the Ascidian Lissoclinum patella: studies on the solution- and solid-state conformations von McDonald, Leonard A, Foster, Mark P, Phillips, Dennis R, Ireland, Chris M, Lee, Angela Y, Clardy, Jon

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FTMS structure elucidation of natural products: application to muraymycin antibiotics using ESI multi-CHEF SORI-CID FTMS(n), the top-down/bottom-up approach, and HPLC ESI capillary... von McDonald, Leonard A, Barbieri, Laurel R, Carter, Guy T, Kruppa, Gary, Feng, Xidong, Lotvin, Jason A, Siegel, Marshall M

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Rare 1,2'-binaphthyls Produced by Nodulisporium hinnuleum Smith (ATCC 36102) von Schlingman, Gerhard, Luckman, Scott, McDonald, Leonard A, Koehn, Frank E

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FTMS Structure Elucidation of Natural Products:  Application to Muraymycin Antibiotics Using ESI Multi-CHEF SORI-CID FTMSn, the Top-Down/Bottom-Up Approach, and HPLC ESI Capillary-... von MCDONALD, Leonard A., BARBIERI, Laurel R., CARTER, Guy T., KRUPPA, Gary, FENG, Xidong, LOTVIN, Jason A., SIEGEL, Marshall M.

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Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of Their derivatives von Lin, Yang-I, Li, Zhong, Francisco, Gerardo D, McDonald, Leonard A, Davis, Rachel A, Singh, Guy, Yang, Youjun, Mansour, Tarek S

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In Support of the Original Medermycin/Lactoquinomycin A Structure von Williamson, R. Thomas, McDonald, Leonard A, Barbieri, Laurel R, Carter, Guy T

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Inhibition of Topoisomerase II Catalytic Activity by Pyridoacridine Alkaloids from a Cystodytes sp. Ascidian: A Mechanism for the Apparent Intercalator-Induced Inhibition of Topois... von McDonald, Leonard A, Eldredge, Glenn S, Barrows, Louis R, Ireland, Chris M

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Spiroxins, DNA cleaving antitumor antibiotics from a marine-derived fungus von McDonald, Leonard A., Abbanat, Darren R., Barbieri, Laurel R., Bernan, Valerie S., Discafani, Carolyn M., Greenstein, Michael, Janota, Katarzyna, Korshalla, Joseph D., Lassota, Piotr, Tischler, Mark, Carter, Guy T.

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FTMS Structure Elucidation of Natural Products:  Application to Muraymycin Antibiotics Using ESI Multi-CHEF SORI-CID FTMS n , the Top-Down/Bottom-Up Approach, and HPLC ESI Capillar... von McDonald, Leonard A, Barbieri, Laurel R, Carter, Guy T, Kruppa, Gary, Feng, Xidong, Lotvin, Jason A, Siegel, Marshall M

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