Synthesis and Activity of New Aryl- and Heteroaryl-Substituted Pyrazole Inhibitors of the Transforming Growth Factor-β Type I Receptor Kinase Domain von Sawyer, J. Scott, Anderson, Bryan D, Beight, Douglas W, Campbell, Robert M, Jones, Michael L, Herron, David K, Lampe, John W, McCowan, Jefferson R, McMillen, William T, Mort, Nicholas, Parsons, Stephen, Smith, Edward C. R, Vieth, Michal, Weir, Leonard C, Yan, Lei, Zhang, Faming, Yingling, Jonathan M

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Benzylamine antioxidants: relationship between structure, peroxyl radical scavenging, lipid peroxidation inhibition and cytoprotection von Yu, Melvin J, McCowan, Jefferson R, Phebus, Lee A, Towner, Richard D, Ho, Peter P. K, Keith, Priscilla T, Luttman, Charlotte A, Saunders, Royal D, Ruterbories, Kenneth J

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Diamino Benzo[b]thiophene Derivatives as a Novel Class of Active Site Directed Thrombin Inhibitors. 5. Potency, Efficacy, and Pharmacokinetic Properties of Modified C-3 Side Chain... von Sall, Daniel J, Bailey, Dianna L, Bastian, Jolie A, Buben, John A, Chirgadze, Nickolay Y, Clemens-Smith, Amy C, Denney, Michael L, Fisher, Matthew J, Giera, Deborah D, Gifford-Moore, Donetta S, Harper, Richard W, Johnson, Lea M, Klimkowski, Valentine J, Kohn, Todd J, Lin, Ho-Shen, McCowan, Jefferson R, Palkowitz, Alan D, Richett, Michael E, Smith, Gerald F, Snyder, David W, Takeuchi, Kumiko, Toth, John E, Zhang, Minsheng

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Fibrinogen Receptor (GPIIb-IIIa) Antagonists Derived from 5,6-Bicyclic Templates. Amidinoindoles, Amidinoindazoles, and Amidinobenzofurans Containing the N-α-Sulfonamide Carboxylic... von Su, Ting, Naughton, Mary Ann H, Smyth, Mark S, Rose, Jack W, Arfsten, Ann E, McCowan, Jefferson R, Jakubowski, Joseph A, Wyss, Virginia L, Ruterbories, Kenneth J, Sall, Daniel J, Scarborough, Robert M

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Use of Conformationally Restricted Benzamidines as Arginine Surrogates in the Design of Platelet GPIIb-IIIa Receptor Antagonists von Sall, Daniel J, Arfsten, Ann E, Bastian, Jolie A, Denney, Michael L, Harms, Cathy S, McCowan, Jefferson R, Morin, John M, Rose, Jack W, Scarborough, Robert M, Smyth, Mark S, Um, Suzane L, Utterback, Barbara G, Vasileff, Robert T, Wikel, James H, Wyss, Virginia L, Jakubowski, Joseph A

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Quinazolinone cholecystokinin-B receptor ligands von Yu, Melvin J, Thrasher, K. Jeff, McCowan, Jefferson R, Mason, Norma R, Mendelsohn, Laurane G

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Dibasic benzo[ b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. 2. Exploring interactions at the proximal (S 2) binding site von Sall, Daniel J., Briggs, Stephen L., Chirgadze, Nickolay Y., Clawson, David K., Gifford-Moore, Donetta S., Klimkowski, Valentine J., McCowan, Jefferson R., Smith, Gerald F., Wikel, James H.

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Synthesis and x-ray crystallographic analysis of quinazolinone cholecystokinin/gastrin receptor ligands von Yu, Melvin J, McCowan, Jefferson R, Mason, Norman R, Deeter, Jack B, Mendelsohn, Laurane G

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Atrial natriuretic peptide receptor modulators: effects of disubstituted quinazolines on receptor binding and in vitro biological activity von Yu, Melvin J, McCowan, Jefferson R, Steinberg, Mitchell I, Wiest, Sally A, Wyss, Virginia L, Horng, Jong Sin

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Phenothiazines as lipid peroxidation inhibitors and cytoprotective agents von Yu, Melvin J, McCowan, Jefferson R, Thrasher, K. Jeff, Keith, Priscilla T, Luttman, Charlotte A, Ho, Peter P. K, Towner, Richard D, Bertsch, Barbara, Horng, J. S

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Stabase-protected 2-chloroallylamine: a useful synthon for primary allylic amines via nickel-catalyzed cross-coupling von Bargar, Thomas M, McCowan, Jefferson R, McCarthy, James R, Wagner, Eugene R

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Dibasic benzo[ b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 4. SAR studies on the conformationally restricted C3-side chain of hydroxybenzo... von Takeuchi, Kumiko, Kohn, Todd J., Sall, Daniel J., Denney, Michael L., McCowan, Jefferson R., Smith, Gerry F., Gifford-Moore, Donetta S.

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Dibasic Benzo[b]thiophene Derivatives as a Novel Class of Active Site-Directed Thrombin Inhibitors. 1. Determination of the Serine Protease Selectivity, Structure−Activity Relation... von Sall, Daniel J, Bastian, Jolie A, Briggs, Stephen L, Buben, John A, Chirgadze, Nickolay Y, Clawson, David K, Denney, Michael L, Giera, Deborah D, Gifford-Moore, Donetta S, Harper, Richard W, Hauser, Kenneth L, Klimkowski, Valentine J, Kohn, Todd J, Lin, Ho-Shen, McCowan, Jefferson R, Palkowitz, Alan D, Smith, Gerald F, Takeuchi, Kumiko, Thrasher, Kenneth J, Tinsley, Jennifer M, Utterback, Barbara G, Yan, Sau-Chi B, Zhang, Minsheng

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Solid phase chemistry approach to the SAR development of a novel class of active site-directed thrombin inhibitors von Johnson, Mary George, Bronson, Duane D., Gillespie, Jan E., Gifford-Moore, Donetta S., Kalter, Kyomi, Lynch, Michael P., McCowan, Jefferson R., Redick, Catherine C., Sall, Daniel J., Smith, Gerald F., Foglesong, Robert J.

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A phenothiazine derivative reduces rat brain damage after global or focal ischemia von Yu, M J, McCowan, J R, Smalstig, E B, Bennett, D R, Roush, M E, Clemens, J A

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Platelet glycoprotein IIb–IIIa receptor (GPIIb–IIIa) antagonists derived from amidinoindoles von Sall, Daniel J., Arfsten, Ann E., Berry, Dennis R., Denney, Michael L., Harms, Cathy S., McCowan, Jefferson R., Ray, Judith K., Scarborough, Robert M., Um, Suzane L., Utterback, Barbara G., Jakubowski, Joseph A.

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Enzymic and nonenzymic lipid peroxidation: inhibition by substituted phenoxazines von Yu, Melvin J., McCowan, Jefferson R., Bertsch, Barbara, Ho, Peter P.K.

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Phenothiazine and phenoxazine derivatives of nafazatrom. In vitro evaluation as 5-lipoxygenase and iron-dependent lipid peroxidation inhibitors von Yu, Melvin J., McCowan, Jefferson R., Bertsch, Barbara, Ho, Peter P.K., Phebus, Lee A., Ruterbories, Kenneth J., Lindstrom, Terry D., Smallwood, Jeffrey K., Simpson, Paul J.

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Structurally novel antiarrhythmic / antioxidant quinazolines von Yu, Melvin J., McCowan, Jefferson R., Towner, Richard D., Ho, Peter P.K., Phebus, Lee A., Ruterbories, Kenneth J., Lindstrom, Terry D., Boyd, Robert, Jackson, William T., Ertel, Phillip J., Steinberg, Mitchell I., Murphy, Anthony, Breau, Alan, Donald Pollock, G., Hahn, Richard A.

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Atrial natriuretic peptide modulators: Dissociation of receptor binding and particulate guanylate cyclase activity von Horng, Jong S., Wyss, Virginia L., Schirmer, Elmer W., McCowan, Jefferson R., Yu, Melvin J.

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