Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure von Dean, J L, Thangavel, C, McClendon, A K, Reed, C A, Knudsen, E S

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Retraction Note: Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly von Braden, W. A., McClendon, A. K., Knudsen, E. S.

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Targeting cell cycle and hormone receptor pathways in cancer von Comstock, C E S, Augello, M A, Goodwin, J F, de Leeuw, R, Schiewer, M J, Ostrander, W F, Burkhart, R A, McClendon, A K, McCue, P A, Trabulsi, E J, Lallas, C D, Gomella, L G, Centenera, M M, Brody, J R, Butler, L M, Tilley, W D, Knudsen, K E

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RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1 von Reed, C A, Mayhew, C N, McClendon, A K, Yang, X, Witkiewicz, A, Knudsen, E S

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Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context von Dean, J L, McClendon, A K, Stengel, K R, Knudsen, E S

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Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly von BRADEN, W. A, MCCLENDON, A. K, KNUDSEN, E. S

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The Geometry of DNA Supercoils Modulates Topoisomerase-Mediated DNA Cleavage and Enzyme Response to Anticancer Drugs von McClendon, A. Kathleen, Osheroff, Neil

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DNA topoisomerase II, genotoxicity, and cancer von McClendon, A K, Osheroff, N

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Human Topoisomerase II alpha Rapidly Relaxes Positively Supercoiled DNA: IMPLICATIONS FOR ENZYME ACTION AHEAD OF REPLICATION FORKS von McClendon, AKathleen, Rodriguez, AChapin, Osheroff, Neil

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RETRACTED ARTICLE: Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly von Braden, W A, McClendon, A K, Knudsen, E S

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Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal von Frøhlich, Rikke From, Veigaard, Christopher, Andersen, Félicie Faucon, McClendon, A. Kathleen, Gentry, Amanda C, Andersen, Anni Hangaard, Osheroff, Neil, Stevnsner, Tinna, Knudsen, Birgitta Ruth

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Ability of Viral Topoisomerase II To Discern the Handedness of Supercoiled DNA: Bimodal Recognition of DNA Geometry by Type II Enzymes von McClendon, A K, Dickey, J S, Osheroff, N

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P2-02-10: Differential Targeting of the RB-Pathway To Expand the Therapeutic Index in the Treatment of Triple Negative Breast Cancer von Knudsen, ES, Dean, J, Thangavel, C, Ertel, A, Witkiewicz, AK, McClendon, AK

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Biological characterization of MLN944: a potent DNA binding agent von Sappal, Darshan S, McClendon, A Kathleen, Fleming, James A, Thoroddsen, Vala, Connolly, Kelly, Reimer, Corinne, Blackman, Ronald K, Bulawa, Christine E, Osheroff, Neil, Charlton, Peter, Rudolph-Owen, Laura A

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The influence of temperature and moisture contents regimes on the aerobic microbial activity of a biosolids composting blend von Liang, C, Das, K.C, McClendon, R.W

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Dynamic architecture of a protein kinase von McClendon, Christopher L, Kornev, Alexandr P, Gilson, Michael K, Taylor, Susan S

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Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors von Dean, Jeffry L., McClendon, A. Kathleen, Hickey, Theresa E., Butler, Lisa M., Tilley, Wayne D., Witkiewicz, Agnieszka K., Knudsen, Erik S.

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Ivermectin performance in horses diagnosed with equine endocrine disorders von Nielsen, M.K., Finnerty, C.A., Ripley, N.E., Page, A.E., McClendon, M.E., Adams, A.A.

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Sulfated glycopeptide nanostructures for multipotent protein activation von Lee, Sungsoo S., Fyrner, Timmy, Chen, Feng, Álvarez, Zaida, Sleep, Eduard, Chun, Danielle S., Weiner, Joseph A., Cook, Ralph W., Freshman, Ryan D., Schallmo, Michael S., Katchko, Karina M., Schneider, Andrew D., Smith, Justin T., Yun, Chawon, Singh, Gurmit, Hashmi, Sohaib Z., McClendon, Mark T., Yu, Zhilin, Stock, Stuart R., Hsu, Wellington K., Hsu, Erin L., Stupp, Samuel I.

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RB Restricts DNA Damage-Initiated Tumorigenesis through an LXCXE-Dependent Mechanism of Transcriptional Control von Bourgo, Ryan J., Thangavel, Chellappagounder, Ertel, Adam, Bergseid, Jacqueline, McClendon, A. Kathleen, Wilkens, Ludwig, Witkiewicz, Agnieszka K., Wang, Jean Y.J., Knudsen, Erik S.

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