Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid‑4 (TRPV4) von Brooks, Carl A, Barton, Linda S, Behm, David J, Brnardic, Edward J, Costell, Melissa H, Holt, Dennis A, Jolivette, Larry J, Matthews, Jay M, McAtee, John J, McCleland, Brent W, Patterson, Jaclyn R, Pero, Joseph E, Rivero, Ralph A, Roethke, Theresa J, Sanchez, Robert M, Shenje, Raynold, Terrell, Lamont R, Lawhorn, Brian G

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Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid‑4 with in Vivo Activity in a Pulmonary Edema Model von Pero, Joseph E, Matthews, Jay M, Behm, David J, Brnardic, Edward J, Brooks, Carl, Budzik, Brian W, Costell, Melissa H, Donatelli, Carla A, Eisennagel, Stephen H, Erhard, Karl, Fischer, Michael C, Holt, Dennis A, Jolivette, Larry J, Li, Huijie, Li, Peng, McAtee, John J, McCleland, Brent W, Pendrak, Israil, Posobiec, Lorraine M, Rivera, Katrina L.K, Rivero, Ralph A, Roethke, Theresa J, Sender, Matthew R, Shu, Arthur, Terrell, Lamont R, Vaidya, Kalindi, Xu, Xiaoping, Lawhorn, Brian G

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Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X‑ray Fragment Screening von Woolford, Alison J.-A, Pero, Joseph E, Aravapalli, Sridhar, Berdini, Valerio, Coyle, Joseph E, Day, Philip J, Dodson, Andrew M, Grondin, Pascal, Holding, Finn P, Lee, Lydia Y. W, Li, Peng, Manas, Eric S, Marino, Joseph, Martin, Agnes C. L, McCleland, Brent W, McMenamin, Rachel L, Murray, Christopher W, Neipp, Christopher E, Page, Lee W, Patel, Vipulkumar K, Potvain, Florent, Rich, Sharna, Rivero, Ralph A, Smith, Kirsten, Somers, Donald O, Trottet, Lionel, Velagaleti, Ranganadh, Williams, Glyn, Xie, Ren

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Evaluation of Potent and Selective Small-Molecule Antagonists for the CXCR2 Chemokine Receptor von Widdowson, Katherine L, Elliott, John D, Veber, Daniel F, Nie, Hong, Rutledge, Melvin C, McCleland, Brent W, Xiang, Jia-Ning, Jurewicz, Anthony J, Hertzberg, Robert P, Foley, James J, Griswold, Don E, Martin, Lenox, Lee, Judithann M, White, John R, Sarau, Henry M

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Comparison of N, N′-diarylsquaramides and N, N′-diarylureas as antagonists of the CXCR2 chemokine receptor von McCleland, Brent W., Davis, Roderick S., Palovich, Michael R., Widdowson, Katherine L., Werner, Michelle L., Burman, Miriam, Foley, James J., Schmidt, Dulcie B., Sarau, Henry M., Rogers, Martin, Salyers, Kevin L., Gorycki, Peter D., Roethke, Theresa J., Stelman, Gary J., Azzarano, Leonard M., Ward, Keith W., Busch-Petersen, Jakob

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Discovery of potent and orally bioavailable N, N′-diarylurea antagonists for the CXCR2 chemokine receptor von Jin, Qi, Nie, Hong, McCleland, Brent W., Widdowson, Katherine L., Palovich, Michael R., Elliott, John D., Goodman, Richard M., Burman, Miriam, Sarau, Henry M., Ward, Keith W., Nord, Melanie, Orr, Bonnie M., Gorycki, Peter D., Busch-Petersen, Jakob

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Mechanistic Studies of the Zirconium−Triisopropanolamine-Catalyzed Enantioselective Addition of Azide to Cyclohexene Oxide von McCleland, Brent W, Nugent, William A, Finn, M. G

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Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo von Boehm, Jeffrey, Davis, Roderick, Murar, Claudia E., Li, Tindy, McCleland, Brent, Dong, Shuping, Yan, Hongxing, Kerns, Jeffrey, Moody, Christopher J., Wilson, Anthony J., Graves, Alan P., Mentzer, Mary, Qi, Hongwei, Yonchuk, John, Kou, Jen-Pyng, Foley, Joseph, Sanchez, Yolanda, Podolin, Patricia L., Bolognese, Brian, Booth-Genthe, Catherine, Galop, Marc, Wolfe, Lawrence, Carr, Robin, Callahan, James F.

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Discovery of Novel Cyanamide-Based Inhibitors of Cathepsin C von Lainé, Dramane, Palovich, Michael, McCleland, Brent, Petitjean, Emilie, Delhom, Isabelle, Xie, Haibo, Deng, Jianghe, Lin, Guoliang, Davis, Roderick, Jolit, Anais, Nevins, Neysa, Zhao, Baoguang, Villa, Jim, Schneck, Jessica, McDevitt, Patrick, Midgett, Robert, Kmett, Casey, Umbrecht, Sandra, Peck, Brian, Davis, Alicia Bacon, Bettoun, David

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Discovery of Novel 1-Azoniabicyclo[2.2.2]octane Muscarinic Acetylcholine Receptor Antagonists von Lainé, Dramane I, McCleland, Brent, Thomas, Sonia, Neipp, Christopher, Underwood, Brian, Dufour, Jeremy, Widdowson, Katherine L, Palovich, Michael R, Blaney, Frank E, Foley, James J, Webb, Edward F, Luttmann, Mark A, Burman, Miriam, Belmonte, Kristen, Salmon, Michael

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Discovery of Novel l-Azoniabicyclo[2.2.2]octane Muscarinic Acetylcholine Receptor Antagonists von LAINE, Dramane I, MCCLELAND, Brent, WEBB, Edward F, LUTTMANN, Mark A, BURMAN, Miriam, BELMONTE, Kristen, SALMON, Michael, THOMAS, Sonia, NEIPP, Christopher, UNDERWOOD, Brian, DUFOUR, Jeremy, WIDDOWSON, Katherine L, PALOVICH, Michael R, BLANEY, Frank E, FOLEY, James J

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Homogeneous catalysis as a tool for organic synthesis von Nugent, W. A., Licini, G., Bonchio, Marcella, Bortolini, Olga, Finn, M. G., McCleland, B. W.

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MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS von NEIPP CHRISTOPHER E, PALOVICH MICHAEL R, THOMAS SONIA M, MCCLELAND BRENT W, LAINE DRAMANE I

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LU92565I von THOMAS Sonia, M, MCCLELAND Brent, W, NEIPP Christopher, E, PALOVICH Michael, R, LAINE Dramane, I

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Muskariniske acetylkolinreceptorantagonister, farmasøytiske preparater samt slike forbindelser for anvendelse von Laine, Dramane Ibrahim, McCleland, Brent W, Palovich, Michael R, Neipp, Christopher E, Thomas, Sonia M

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Arylcyclohexyl pyrazoles as NRF2 regulators von Kerns, Jeffrey K, Woolford, Alison Jo-Anne, Griffiths-Jones, Charlotte Mary, Norton, David, McCleland, Brent W, Pero, Joseph E, Verdonk, Marinus Leendert, Callahan, James, Nie, Hong, Davies, Thomas Glanmor, Li, Tindy, Heightman, Thomas Daniel, Howard, Steven

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MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS von NEIPP CHRISTOPHER E, PALOVICH MICHAEL R, THOMAS SONIA M, LAINE DRAMANE IBRAHIM, MCCLELAND BRENT W

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Muscarinic acetylcholine receptor antagonists von NEIPP CHRISTOPHER E, PALOVICH MICHAEL R, THOMAS SONIA M, LAINE DRAMANE IBRAHIM, MCCLELAND BRENT W

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MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS von NEIPP CHRISTOPHER E, PALOVICH MICHAEL R, THOMAS SONIA M, LAINE DRAMANE IBRAHIM, MCCLELAND BRENT W

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ARYLCYCLOHEXYL PYRAZOLES AS NRF2 REGULATORS von KERNS, Jeffrey K, LI, Tindy, VERDONK, Marinus Leendert, GRIFFITHS-JONES, Charlotte Mary, DAVIES, Thomas Glanmor, WOOLFORD, Alison Jo-Anne, HEIGHTMAN, Thomas Daniel, NORTON, David, CALLAHAN, James, PERO, Joseph E, NIE, Hong, HOWARD, Steven, McCLELAND, Brent W

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