Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivo von Rousalova, Ilona, Banerjee, Sulagna, Sangwan, Veena, Evenson, Kristen, McCauley, Joel A, Kratzke, Robert, Vickers, Selwyn M, Saluja, Ashok, D'Cunha, Jonathan

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The RhoA/Rho Kinase Pathway Regulates Nuclear Localization of Serum Response Factor von Liu, Hong Wei, Halayko, Andrew J, Fernandes, Darren J, Harmon, Gregory S, McCauley, Joel A, Kocieniewski, Pawel, McConville, John, Fu, Yiping, Forsythe, Sean M, Kogut, Paul, Bellam, Shashi, Dowell, Maria, Churchill, Jason, Lesso, Heinte, Kassiri, Kamrouz, Mitchell, Richard W, Hershenson, Marc B, Camoretti-Mercado, Blanca, Solway, Julian

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Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma von Jacobson, Blake A, Chen, Esther Z, Tang, Shaogeng, Belgum, Holly Sedgwick, McCauley, Joel A, Evenson, Kristen A, Etchison, Ryan G, Jay-Dixon, Joe, Patel, Manish R, Raza, Ahmad, Saluja, Ashok K, D'Cunha, Jonathan, Kratzke, Robert A

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Structure and Transcription of the Human m3 Muscarinic Receptor Gene von Forsythe, Sean M, Kogut, Paul C, McConville, John F, Fu, Yiping, McCauley, Joel A, Halayko, Andrew J, Liu, Hong Wei, Kao, Allen, Fernandes, Darren J, Bellam, Shashi, Fuchs, Elaine, Sinha, Satrajit, Bell, Graeme I, Camoretti-Mercado, Blanca, Solway, Julian

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Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma von Jacobson, Blake A., Chen, Esther Z., Tang, Shaogeng, Belgum, Holly Sedgwick, McCauley, Joel A., Evenson, Kristen A., Etchison, Ryan G., Jay-Dixon, Joe, Patel, Manish R., Raza, Ahmad, Saluja, Ashok K., D’Cunha, Jonathan, Kratzke, Robert A.

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Abstract 2347: Translational control and lung cancer: eIF4F activation promotes tumorigenesis in vivo von McCauley, Joel A., Evenson, Kristen, Truitt, Morgan, Kratzke, Robert, Polunovsky, Vitaly, Ruggero, Davide, BItterman, Peter, D'Cunha, Jonathan

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Antiretroviral Therapy for the Prevention of HIV-1 Transmission von Cohen, Myron S, Chen, Ying Q, McCauley, Marybeth, Gamble, Theresa, Hosseinipour, Mina C, Kumarasamy, Nagalingeswaran, Hakim, James G, Kumwenda, Johnstone, Grinsztejn, Beatriz, Pilotto, Jose H.S, Godbole, Sheela V, Chariyalertsak, Suwat, Santos, Breno R, Mayer, Kenneth H, Hoffman, Irving F, Eshleman, Susan H, Piwowar-Manning, Estelle, Cottle, Leslie, Zhang, Xinyi C, Makhema, Joseph, Mills, Lisa A, Panchia, Ravindre, Faesen, Sharlaa, Eron, Joseph, Gallant, Joel, Havlir, Diane, Swindells, Susan, Elharrar, Vanessa, Burns, David, Taha, Taha E, Nielsen-Saines, Karin, Celentano, David D, Essex, Max, Hudelson, Sarah E, Redd, Andrew D, Fleming, Thomas R

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Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries von Liu, Zhanju, Liu, Ruize, Gao, Han, Jung, Seulgi, Gao, Xiang, Sun, Ruicong, Liu, Xiaoming, Kim, Yongjae, Lee, Ho-Su, Kawai, Yosuke, Nagasaki, Masao, Umeno, Junji, Tokunaga, Katsushi, Kinouchi, Yoshitaka, Masamune, Atsushi, Shi, Wenzhao, Shen, Chengguo, Guo, Zhenglin, Yuan, Kai, Zhu, Shu, Li, Dalin, Liu, Jianjun, Ge, Tian, Cho, Judy, Daly, Mark J., McGovern, Dermot P. B., Ye, Byong Duk, Song, Kyuyoung, Kakuta, Yoichi, Li, Mingsong, Huang, Hailiang

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"I Don't Know What the Hell You'd Call It": A Qualitative Thematic Synthesis of Men's Experiences With Sexual Violence in Adulthood as Contextualized by Hegemonic Masculinity von PettyJohn, Morgan E., Reid, Taylor A., Cary, Kyla M., Greer, Kirsten M., Nason, Jacob A., Agundez, Juan C., Graves, Carin, McCauley, Heather L.

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Stress Training Improves Performance During a Stressful Flight von McClernon, Christopher K., McCauley, Michael E., O’Connor, Paul E., Warm, Joel S.

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Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity von Scott, Jack D, DeMong, Duane E, Greshock, Thomas J, Basu, Kallol, Dai, Xing, Harris, Joel, Hruza, Alan, Li, Sarah W, Lin, Sue-Ing, Liu, Hong, Macala, Megan K, Hu, Zhiyong, Mei, Hong, Zhang, Honglu, Walsh, Paul, Poirier, Marc, Shi, Zhi-Cai, Xiao, Li, Agnihotri, Gautam, Baptista, Marco A. S, Columbus, John, Fell, Matthew J, Hyde, Lynn A, Kuvelkar, Reshma, Lin, Yinghui, Mirescu, Christian, Morrow, John A, Yin, Zhizhang, Zhang, Xiaoping, Zhou, Xiaoping, Chang, Ronald K, Embrey, Mark W, Sanders, John M, Tiscia, Heather E, Drolet, Robert E, Kern, Jonathan T, Sur, Sylvie M, Renger, John J, Bilodeau, Mark T, Kennedy, Matthew E, Parker, Eric M, Stamford, Andrew W, Nargund, Ravi, McCauley, John A, Miller, Michael W

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Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial von Grinsztejn, Beatriz, MD, Hosseinipour, Mina C, MD, Ribaudo, Heather J, PhD, Swindells, Susan, MBBS, Eron, Joseph, MD, Chen, Ying Q, PhD, Wang, Lei, PhD, Ou, San-San, MS, Anderson, Maija, MN, McCauley, Marybeth, MPH, Gamble, Theresa, PhD, Kumarasamy, Nagalingeshwaran, MB, Hakim, James G, MD, Kumwenda, Johnstone, FRCP, Pilotto, Jose H S, MD, Godbole, Sheela V, MD, Chariyalertsak, Suwat, MD, de Melo, Marineide Gonçalves, MD, Mayer, Kenneth H, MD, Eshleman, Susan H, MD, Piwowar-Manning, Estelle, MT, Makhema, Joseph, FRCP, Mills, Lisa A, MD, Panchia, Ravindre, MBBCh, Sanne, Ian, MBBCh, Gallant, Joel, MD, Hoffman, Irving, PA, Taha, Taha E, MBBS, Nielsen-Saines, Karin, MD, Celentano, David, ScD, Essex, Max, DVM, Havlir, Diane, MD, Cohen, Myron S, Dr

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Prevention of HIV-1 Infection with Early Antiretroviral Therapy von Cohen, Myron S, Chen, Ying Q, McCauley, Marybeth, Gamble, Theresa, Hosseinipour, Mina C, Kumarasamy, Nagalingeswaran, Hakim, James G, Kumwenda, Johnstone, Grinsztejn, Beatriz, Pilotto, Jose H.S, Godbole, Sheela V, Mehendale, Sanjay, Chariyalertsak, Suwat, Santos, Breno R, Mayer, Kenneth H, Hoffman, Irving F, Eshleman, Susan H, Piwowar-Manning, Estelle, Wang, Lei, Makhema, Joseph, Mills, Lisa A, de Bruyn, Guy, Sanne, Ian, Eron, Joseph, Gallant, Joel, Havlir, Diane, Swindells, Susan, Ribaudo, Heather, Elharrar, Vanessa, Burns, David, Taha, Taha E, Nielsen-Saines, Karin, Celentano, David, Essex, Max, Fleming, Thomas R

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Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease von Somineni, Hari K., Nagpal, Sini, Venkateswaran, Suresh, Cutler, David J., Okou, David T., Haritunians, Talin, Simpson, Claire L., Begum, Ferdouse, Datta, Lisa W., Quiros, Antonio J., Seminerio, Jenifer, Mengesha, Emebet, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Iskandar, Heba, Dryden, Gerald W., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kuemmerle, John F., Lazarev, Mark, Li, Ellen, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Patel, Ashish S., Pekow, Joel, Saeed, Shehzad A., Valentine, John F., Wang, Ming-Hsi, McCauley, Jacob L., Abreu, Maria T., Jester, Traci, Molle-Rios, Zarela, Palle, Sirish, Scherl, Ellen J., Kwon, John, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Zwick, Michael E., Stevens, Christine, Daly, Mark J., Cho, Judy H., Gibson, Greg, McGovern, Dermot P.B., Brant, Steven R., Kugathasan, Subra

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The genomic basis of the plant island syndrome in Darwin’s giant daisies von Cerca, José, Petersen, Bent, Lazaro-Guevara, José Miguel, Rivera-Colón, Angel, Birkeland, Siri, Vizueta, Joel, Li, Siyu, Li, Qionghou, Loureiro, João, Kosawang, Chatchai, Díaz, Patricia Jaramillo, Rivas-Torres, Gonzalo, Fernández-Mazuecos, Mario, Vargas, Pablo, McCauley, Ross A., Petersen, Gitte, Santos-Bay, Luisa, Wales, Nathan, Catchen, Julian M., Machado, Daniel, Nowak, Michael D., Suh, Alexander, Sinha, Neelima R., Nielsen, Lene R., Seberg, Ole, Gilbert, M. Thomas P., Leebens-Mack, James H., Rieseberg, Loren H., Martin, Michael D.

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Treatment of Breast and Lung Cancer Cells with a N-7 Benzyl Guanosine Monophosphate Tryptamine Phosphoramidate Pronucleotide (4Ei-1) Results in Chemosensitization to Gemcitabine an... von Li, Shui, Jia, Yan, Jacobson, Blake, McCauley, Joel, Kratzke, Robert, Bitterman, Peter B., Wagner, Carston R.

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Structure–Activity Relationships of Natural and Semisynthetic Plecomacrolides Suggest Distinct Pathways for HIV‑1 Immune Evasion and Vacuolar ATPase-Dependent Lysosomal Acidificati... von McCauley, Morgan, Huston, Matthew, Condren, Alanna R., Pereira, Filipa, Cline, Joel, Yaple-Maresh, Marianne, Painter, Mark M., Zimmerman, Gretchen E., Robertson, Andrew W., Carney, Nolan, Goodall, Christopher, Terry, Valeri, Müller, Rolf, Sherman, David H., Collins, Kathleen L.

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Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling von Johnson, Brett V., Alexander, Suzy, Vega, Michelle Sanchez, Domingo, Deepti, Oh, Tracey, Lines, Matthew, Grønborg, Sabine, Mercier, Sandra, Küry, Sébastien, Billette de Villemeur, Thierry, Koolen, David A., Sa, Joaquim, Santiago-Fernández, Olaya, Fernández-Jaén, Alberto, Goldstein, Amy, Madan-Khetarpal, Suneeta, Sullivan, Jennifer A., Bacino, Carlos A., Baker, Eva, Bellen, Hugo J., Bernstein, Jonathan A., Bick, David P., Butte, Manish J., Davids, Mariska, Davidson, Jean M., Dayal, Jyoti G., Dhar, Shweta U., Douine, Emilie D., Draper, David D., Emrick, Lisa T., Esteves, Cecilia, Estwick, Tyra, Fernandez, Liliana, Ferreira, Carlos, Forghani, Irman, Friedman, Noah D., Gahl, William A., Godfrey, Rena A., Hanchard, Neil A., Jiang, Yong-hui, Karaviti, Lefkothea, Korrick, Susan, Koziura, Mary, Krier, Joel B., Lanpher, Brendan C., LeBlanc, Kimberly, Lee, Brendan H., Liu, Xue Zhong, Marwaha, Shruti, McCauley, Jacob, Morimoto, Marie, Nath, Avi, Nelson, Stan F., Newman, John H., Oglesbee, Devin, Orengo, James P., Pak, Stephen, Parker, Neil H., Phillips, John A., Reuter, Chloe M., Rives, Lynette, Robertson, Amy K., Rodan, Lance H., Sampson, Jacinda B., Schedl, Timothy, Shakachite, Lisa, Sharma, Prashant, Signer, Rebecca, Silverman, Edwin K., Sinsheimer, Janet S., Tekin, Mustafa, Thorson, Willa, Tran, Alyssa A., Vogel, Tiphanie P., Wahl, Colleen E., Walsh, Chris A., Wang, Lee-kai, Wangler, Michael F., Worthey, Elizabeth A., Yu, Guoyun, Zastrow, Diane B., Zhao, Chunli, Gahl, William, Sullivan, Jennifer A., Barnett, Sarah S., Perry, M. Scott, Schuette, Jane L., Smith, Laurie D., Rosenfeld, Jill A., Bhoj, Elizabeth, Kaplan, Paige, Oegema, Renske, Armstrong, Martin, Lin, Angela E., Hollander, Nicolette den, Hoffer, Mariëtte J.V., Mosher, Theresa Mihalic, Tezcan, Kamer, Penzes, Peter, Piper, Michael

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De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation von Mao, Dongxue, Reuter, Chloe M., Farrow, Emily G., Rosenfeld, Jill A., Mackenzie, Katherine M., Küry, Sébastien, Genetti, Casie A., Alejandro, Mercedes, Agrawal, Pankaj B., Alvey, Justin, Ashley, Euan A., Balasubramanyam, Ashok, Beck, Anita, Bellen, Hugo J., Berg-Rood, Beverly, Bernier, Raphael, Bivona, Stephanie, Bohnsack, John, Briere, Lauren C., Burke, Elizabeth A., Butte, Manish J., Carrasquillo, Olveen, Cogan, Joy D., Cole, F. Sessions, Colley, Heather A., Cooper, Cynthia M., Craigen, William J., Cunningham, Michael, Dasari, Surendra, Dayal, Jyoti G., Dhar, Shweta U., Emrick, Lisa T., Estwick, Tyra, Ferreira, Carlos, Fieg, Elizabeth L., Fogel, Brent L., Forghani, Irman, Gahl, William A., Godfrey, Rena A., Goldman, Alica M., Hahn, Sihoun, Hanchard, Neil A., Hing, Anne, Holm, Ingrid A., Huang, Yong, Jamal, Fariha, Jayadev, Suman, Karaviti, Lefkothea, Kelley, Emily G., Kohane, Isaac S., Kohler, Jennefer N., Krakow, Deborah, Korrick, Susan, Koziura, Mary, Krier, Joel B., Lam, Byron, Lanpher, Brendan C., Lanza, Ian R., Lee, Brendan H., Lewis, Richard A., Loo, Sandra K., Majcherska, Marta M., Malicdan, May Christine V., Mamounas, Laura A., Markello, Thomas C., Martin, Martin G., Martínez-Agosto, Julian A., McCormack, Colleen E., Merritt, J. Lawrence, Moretti, Paolo M., Mulvihill, John J., Murdock, David R., Nickerson, Deborah, Pallais, J. Carl, Posey, Jennifer E., Potocki, Lorraine, Raja, Archana N., Renteria, Genecee, Rosenfeld, Jill A., Samson, Susan L., Schedl, Timothy, Shakachite, Lisa, Signer, Rebecca, Silverman, Edwin K., Sybert, Virginia, Tekin, Mustafa, Thorson, Willa, Tran, Alyssa A., Urv, Tiina K., Wahl, Colleen E., Wegner, Daniel, Wheeler, Matthew T., Yamamoto, Shinya, Yang, John, Yoon, Amanda J., Yu, Guoyun, Zastrow, Diane B., Zhao, Chunli, Bernstein, Jonathan A., Chao, Hsiao-Tuan

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SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia von Srivastava, Siddharth, Shaked, Hagar Mor, Gable, Kenneth, Gupta, Sita D, Pan, Xueyang, Somashekarappa, Niranjanakumari, Han, Gongshe, Mohassel, Payam, Gotkine, Marc, Doney, Elizabeth, Goldenberg, Paula, Tan, Queenie K G, Gong, Yi, Kleinstiver, Benjamin, Wishart, Brian, Cope, Heidi, Pires, Claudia Brito, Stutzman, Hannah, Spillmann, Rebecca C, Sadjadi, Reza, Elpeleg, Orly, Lee, Chia-Hsueh, Bellen, Hugo J, Edvardson, Simon, Eichler, Florian, Dunn, Teresa M

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