Platelet Mechanotransduction von Hansen, Caroline E, Qiu, Yongzhi, McCarty, Owen J.T, Lam, Wilbur A

Volltext

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial von Lorentz, Christina U, Verbout, Norah G, Wallisch, Michael, Hagen, Matthew W, Shatzel, Joseph J, Olson, Sven R, Puy, Cristina, Hinds, Monica T, McCarty, Owen J.T, Gailani, David, Gruber, András, Tucker, Erik I

Volltext

The prothrombotic activity of cancer cells in the circulation von Mitrugno, Annachiara, Tormoen, Garth W, Kuhn, Peter, McCarty, Owen J.T

Volltext

The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear von Loren, Cassandra P, Aslan, Joseph E, Rigg, Rachel A, Nowak, Marie S, Healy, Laura D, Gruber, András, Druker, Brian J, McCarty, Owen J.T

Volltext

Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo von Zilberman-Rudenko, Jevgenia, Deguchi, Hiroshi, Shukla, Meenal, Oyama, Yoshimasa, Orje, Jennifer N., Guo, Zihan, Wyseure, Tine, Mosnier, Laurent O., McCarty, Owen J.T., Ruggeri, Zaverio M., Eckle, Tobias, Griffin, John H.

Volltext

The amniotic fluid proteome changes across gestation in humans and rhesus macaques von Shorey-Kendrick, Lyndsey E., Crosland, B. Adam, Spindel, Eliot R., McEvoy, Cindy T., Wilmarth, Phillip A., Reddy, Ashok P., Zientek, Keith D., Roberts, Victoria H. J., D’Mello, Rahul J., Ryan, Kimberly S., Olyaei, Amy F., Hagen, Olivia L., Drake, Matthew G., McCarty, Owen J.T., Scottoline, Brian P., Lo, Jamie O.

Volltext

Identification of Coagulation Factor XI as a Ligand for Platelet Apolipoprotein E Receptor 2 (ApoER2) von White-Adams, Tara C, Berny, Michelle A, Tucker, Erik I, Gertz, Jacqueline M, Gailani, David, Urbanus, Rolf T, de Groot, Philip G, Gruber, András, McCarty, Owen J.T

Volltext

The hemostatic role of factor XI von Puy, Cristina, Rigg, Rachel A, McCarty, Owen J.T

Volltext

Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo von Healy, Laura D., Puy, Cristina, Fernández, José A., Mitrugno, Annachiara, Keshari, Ravi S., Taku, Nyiawung A., Chu, Tiffany T., Xu, Xiao, Gruber, András, Lupu, Florea, Griffin, John H., McCarty, Owen J.T.

Volltext

Microfluidics and coagulation biology von Colace, Thomas V, Tormoen, Garth W, McCarty, Owen J T, Diamond, Scott L

Volltext

Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI) von Puy, Cristina, Ngo, Anh T.P, Pang, Jiaqing, Keshari, Ravi S, Hagen, Matthew W, Hinds, Monica T, Gailani, David, Gruber, András, Lupu, Florea, McCarty, Owen J.T

Volltext

Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen von Ivanov, Ivan, Shakhawat, Ruhama, Sun, Mao-fu, Dickeson, S. Kent, Puy, Cristina, McCarty, Owen J.T, Gruber, Andras, Matafonov, Anton, Gailani, David

Volltext

Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo von Zilberman-Rudenko, Jevgenia, Reitsma, Stéphanie E, Puy, Cristina, Rigg, Rachel A, Smith, Stephanie A, Tucker, Erik I, Silasi, Robert, Merkulova, Alona, McCrae, Keith R, Maas, Coen, Urbanus, Rolf T, Gailani, David, Morrissey, James H, Gruber, András, Lupu, Florea, Schmaier, Alvin H, McCarty, Owen J.T

Volltext

TRPing out Platelet Calcium: TRPM7 (Transient Receptor Potential Melastatin-Like 7) Modulates Calcium Mobilization and Platelet Function via Phospholipase C Interactions von Ngo, Anh T.P, McCarty, Owen J.T, Aslan, Joseph E

Volltext

Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow von Zilberman-Rudenko, Jevgenia, Itakura, Asako, Wiesenekker, Chantal P, Vetter, Ralf, Maas, Coen, Gailani, David, Tucker, Erik I, Gruber, András, Gerdes, Christoph, McCarty, Owen J.T

Volltext

Colocalization of neutrophils, extracellular DNA and coagulation factors during NETosis: Development and utility of an immunofluorescence-based microscopy platform von Healy, Laura D., Puy, Cristina, Itakura, Asako, Chu, Tiffany, Robinson, David K., Bylund, Alan, Phillips, Kevin G., Gardiner, Elizabeth E., McCarty, Owen J.T.

Volltext

Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group von Key, Nigel S, Khorana, Alok A, Mackman, Nigel, McCarty, Owen J T, White, Gilbert C, Francis, Charles W, McCrae, Keith R, Palumbo, Joseph S, Raskob, Gary E, Chan, Andrew T, Sood, Anil K

Volltext

Coated platelets function in platelet-dependent fibrin formation via integrin αIIbβ3 and transglutaminase factor XIII von Mattheij, Nadine J A, Swieringa, Frauke, Mastenbroek, Tom G, Berny-Lang, Michelle A, May, Frauke, Baaten, Constance C F M J, van der Meijden, Paola E J, Henskens, Yvonne M C, Beckers, Erik A M, Suylen, Dennis P L, Nolte, Marc W, Hackeng, Tilman M, McCarty, Owen J T, Heemskerk, Johan W M, Cosemans, Judith M E M

Volltext

The contact pathway and sepsis von Raghunathan, Vikram, Zilberman‐Rudenko, Jevgenia, Olson, Sven R., Lupu, Florea, McCarty, Owen J.T., Shatzel, Joseph J.

Volltext

Differential Roles for the Coagulation Factors XI and XII in Regulating the Physical Biology of Fibrin von Sylman, Joanna L., Daalkhaijav, Uranbileg, Zhang, Ying, Gray, Elliot M., Farhang, Parsa A., Chu, Tiffany T., Zilberman-Rudenko, Jevgenia, Puy, Cristina, Tucker, Erik I., Smith, Stephanie A., Morrissey, James H., Walker, Travis W., Nan, Xiaolin L., Gruber, András, McCarty, Owen J. T.

Volltext