The Remarkable Structural and Functional Organization of the Eukaryotic Pyruvate Dehydrogenase Complexes von Zhou, Z. Hong, McCarthy, Diane B., O'Connor, Catherine M., Reed, Lester J., Stoops, James K.

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3D Electron Microscopy Reveals the Variable Deposition and Protein Dynamics of the Peripheral Pyruvate Dehydrogenase Component about the Core von Gu, Yingqi, Zhou, Z. Hong, McCarthy, Diane B., Reed, Lester J., Stoops, James K.

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Serum protein expression profiling for cancer detection: validation of a SELDI-based approach for prostate cancer von Grizzle, William E, Adam, Bao-Ling L, Bigbee, William L, Conrads, Thomas P, Carroll, Christopher, Feng, Ziding, Izbicka, Elzbieta, Jendoubi, Moncef, Johnsey, Donald, Kagan, Jacob, Leach, Robin J, McCarthy, Diane B, Semmes, O John, Srivastava, Shiv, Srivastava, Sudhir, Thompson, Ian M, Thornquist, Mark D, Verma, Mukesh, Zhang, Zhen, Zou, Zhiqiang

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One-Step Purification of the Recombinant Catalytic Subunit of Pyruvate Dehydrogenase Phosphatase von Soo Choi, Wahn, Yan, Jiangong, McCarthy, Diane B., Hee Park, Seung, Reed, Lester J.

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Health Policy Agenda for the American People von McCarthy, D B

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Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits von Speliotes, Elizabeth K, Yerges-Armstrong, Laura M, Wu, Jun, Hernaez, Ruben, Kim, Lauren J, Palmer, Cameron D, Gudnason, Vilmundur, Eiriksdottir, Gudny, Garcia, Melissa E, Launer, Lenore J, Nalls, Michael A, Clark, Jeanne M, Mitchell, Braxton D, Shuldiner, Alan R, Butler, Johannah L, Tomas, Marta, Hoffmann, Udo, Hwang, Shih-Jen, Massaro, Joseph M, O'Donnell, Christopher J, Sahani, Dushyant V, Salomaa, Veikko, Schadt, Eric E, Schwartz, Stephen M, Siscovick, David S, Voight, Benjamin F, Carr, J Jeffrey, Feitosa, Mary F, Harris, Tamara B, Fox, Caroline S, Smith, Albert V, Kao, W H Linda, Hirschhorn, Joel N, Borecki, Ingrid B

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Genome-wide association of body fat distribution in African ancestry populations suggests new loci von Liu, Ching-Ti, Monda, Keri L, Taylor, Kira C, Lange, Leslie, Demerath, Ellen W, Palmas, Walter, Wojczynski, Mary K, Ellis, Jaclyn C, Vitolins, Mara Z, Liu, Simin, Papanicolaou, George J, Irvin, Marguerite R, Xue, Luting, Griffin, Paula J, Nalls, Michael A, Adeyemo, Adebowale, Liu, Jiankang, Li, Guo, Ruiz-Narvaez, Edward A, Chen, Wei-Min, Chen, Fang, Henderson, Brian E, Millikan, Robert C, Ambrosone, Christine B, Strom, Sara S, Guo, Xiuqing, Andrews, Jeanette S, Sun, Yan V, Mosley, Thomas H, Yanek, Lisa R, Shriner, Daniel, Haritunians, Talin, Rotter, Jerome I, Speliotes, Elizabeth K, Smith, Megan, Rosenberg, Lynn, Mychaleckyj, Josyf, Nayak, Uma, Spruill, Ida, Garvey, W Timothy, Pettaway, Curtis, Nyante, Sarah, Bandera, Elisa V, Britton, Angela F, Zonderman, Alan B, Rasmussen-Torvik, Laura J, Chen, Yii-Der Ida, Ding, Jingzhong, Lohman, Kurt, Kritchevsky, Stephen B, Zhao, Wei, Peyser, Patricia A, Kardia, Sharon L R, Kabagambe, Edmond, Broeckel, Ulrich, Chen, Guanjie, Zhou, Jie, Wassertheil-Smoller, Sylvia, Neuhouser, Marian L, Rampersaud, Evadnie, Psaty, Bruce, Kooperberg, Charles, Manson, Joann E, Kuller, Lewis H, Ochs-Balcom, Heather M, Johnson, Karen C, Sucheston, Lara, Ordovas, Jose M, Palmer, Julie R, Haiman, Christopher A, McKnight, Barbara, Howard, Barbara V, Becker, Diane M, Bielak, Lawrence F, Liu, Yongmei, Allison, Matthew A, Grant, Struan F A, Burke, Gregory L, Patel, Sanjay R, Schreiner, Pamela J, Borecki, Ingrid B, Evans, Michele K, Taylor, Herman, Sale, Michele M, Howard, Virginia, Carlson, Christopher S, Rotimi, Charles N, Cushman, Mary, Harris, Tamara B, Reiner, Alexander P, Cupples, L Adrienne, North, Kari E, Fox, Caroline S

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MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus von Deng, Yun, Zhao, Jian, Sakurai, Daisuke, Kaufman, Kenneth M, Edberg, Jeffrey C, Kimberly, Robert P, Kamen, Diane L, Gilkeson, Gary S, Jacob, Chaim O, Scofield, R Hal, Langefeld, Carl D, Kelly, Jennifer A, Ramsey-Goldman, Rosalind, Petri, Michelle A, Reveille, John D, Vilá, Luis M, Alarcón, Graciela S, Vyse, Timothy J, Pons-Estel, Bernardo A, Freedman, Barry I, Gaffney, Patrick M, Sivils, Kathy Moser, James, Judith A, Gregersen, Peter K, Anaya, Juan-Manuel, Niewold, Timothy B, Merrill, Joan T, Criswell, Lindsey A, Stevens, Anne M, Boackle, Susan A, Cantor, Rita M, Chen, Weiling, Grossman, Jeniffer M, Hahn, Bevra H, Harley, John B, Alarcόn-Riquelme, Marta E, Brown, Elizabeth E, Tsao, Betty P

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Transcatheter Mitral-Valve Repair in Patients with Heart Failure von Stone, Gregg W, Lindenfeld, JoAnn, Abraham, William T, Kar, Saibal, Lim, D. Scott, Mishell, Jacob M, Whisenant, Brian, Grayburn, Paul A, Rinaldi, Michael, Kapadia, Samir R, Rajagopal, Vivek, Sarembock, Ian J, Brieke, Andreas, Marx, Steven O, Cohen, David J, Weissman, Neil J, Mack, Michael J

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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4 von Manku, Harinder, Langefeld, Carl D, Guerra, Sandra G, Malik, Talat H, Alarcon-Riquelme, Marta, Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan A, Brown, Elizabeth E, Criswell, Lindsey A, Freedman, Barry I, Gaffney, Patrick M, Gregersen, Peter A, Guthridge, Joel M, Han, Sang-Hoon, Harley, John B, Jacob, Chaim O, James, Judith A, Kamen, Diane L, Kaufman, Kenneth M, Kelly, Jennifer A, Martin, Javier, Merrill, Joan T, Moser, Kathy L, Niewold, Timothy B, Park, So-Yeon, Pons-Estel, Bernardo A, Sawalha, Amr H, Scofield, R Hal, Shen, Nan, Stevens, Anne M, Sun, Celi, Gilkeson, Gary S, Edberg, Jeff C, Kimberly, Robert P, Nath, Swapan K, Tsao, Betty P, Vyse, Tim J

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure von Henry, Albert, Roselli, Carolina, Sveinbjörnsson, Garðar, Fatemifar, Ghazaleh, Hedman, Åsa K., Morley, Michael P., Helgadottir, Anna, Verweij, Niek, Dehghan, Abbas, Almgren, Peter, Andersson, Charlotte, Backman, Joshua D., Biggs, Mary L., Brandimarto, Jeffrey, Buckbinder, Leonard, Carey, David J., Chasman, Daniel I., Chen, Xu, Chung, Jonathan, Cook, James P., Delgado, Graciela E., Denaxas, Spiros, Dörr, Marcus, Dudley, Samuel C., Esko, Tõnu, Finan, Chris, Gottdiener, John S., Gross, Stefan, Guðbjartsson, Daníel F., Gutmann, Rebecca, Haggerty, Christopher M., Hyde, Craig L., Ingelsson, Erik, Jukema, J. Wouter, Kavousi, Maryam, Khaw, Kay-Tee, Kleber, Marcus E., Køber, Lars, Koekemoer, Andrea, Langenberg, Claudia, Lind, Lars, Lotta, Luca A., Luan, Jian’an, März, Winfried, Melander, Olle, Mordi, Ify R., Morgan, Thomas, Morris, Andrew D., Morris, Andrew P., Morrison, Alanna C., Nelson, Christopher P., Niessner, Alexander, Niiranen, Teemu, O’Donoghue, Michelle L., Owens, Anjali T., Parry, Helen M., Perola, Markus, Rice, Kenneth M., Ridker, Paul M., Rotter, Jerome I., Salo, Perttu, Salomaa, Veikko, Smelser, Diane T., Stender, Steen, Stott, David J., Tammesoo, Mari-Liis, Taylor, Kent D., Teder-Laving, Maris, Thorsteinsdottir, Unnur, Torp-Pedersen, Christian, Trompet, Stella, Tyl, Benoit, Uitterlinden, Andre G., Veluchamy, Abirami, Völker, Uwe, Voors, Adriaan A., Wareham, Nicholas J., Waterworth, Dawn, Weiss, Raul, Wiggins, Kerri L., Yerges-Armstrong, Laura M., Yu, Bing, Zannad, Faiez, Zhao, Jing Hua, Hemingway, Harry, McMurray, John J. V., Yang, Jian, Visscher, Peter M., Malarstig, Anders, Holm, Hilma, Sattar, Naveed, Holmes, Michael V., Cappola, Thomas P., Hingorani, Aroon D., Kuchenbaecker, Karoline, Ellinor, Patrick T., Smith, J. Gustav, Vasan, Ramachandran S., Swerdlow, Daniel I., Lumbers, R. Thomas

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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression von Sakurai, Daisuke, Zhao, Jian, Deng, Yun, Kelly, Jennifer A, Brown, Elizabeth E, Harley, John B, Bae, Sang-Cheol, Alarcόn-Riquelme, Marta E, Edberg, Jeffrey C, Kimberly, Robert P, Ramsey-Goldman, Rosalind, Petri, Michelle A, Reveille, John D, Vilá, Luis M, Alarcón, Graciela S, Kaufman, Kenneth M, Vyse, Timothy J, Jacob, Chaim O, Gaffney, Patrick M, Sivils, Kathy Moser, James, Judith A, Kamen, Diane L, Gilkeson, Gary S, Niewold, Timothy B, Merrill, Joan T, Scofield, R Hal, Criswell, Lindsey A, Stevens, Anne M, Boackle, Susan A, Kim, Jae-Hoon, Choi, Jiyoung, Pons-Estel, Bernardo A, Freedman, Barry I, Anaya, Juan-Manuel, Martin, Javier, Yu, C Yung, Chang, Deh-Ming, Song, Yeong Wook, Langefeld, Carl D, Chen, Weiling, Grossman, Jennifer M, Cantor, Rita M, Hahn, Bevra H, Tsao, Betty P

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Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility von Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Dauriz, Marco, Raghavan, Sridharan, Hidalgo, Bertha, An, Ping, Lu, Yingchang, Ehm, Margaret G, Baldridge, Abigail S, Freitag, Daniel F, Garcia, Melissa E, Hara, Kazuo, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Morrison, Alanna C, Peters, Marjolein J, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Varga, Tibor V, Barbieri, Caterina, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Frånberg, Mattias, Gambaro, Giovanni, Goel, Anuj, Grove, Megan L, Karaleftheri, Maria, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, I T, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Lindgren, Cecilia M, Malerba, Giovanni, Mamakou, Vasiliki, Maruthur, Nisa M, McLeod, Olga, Mohlke, Karen L, Muzny, Donna M, Renström, Frida, Rice, Ken, Sala, Cinzia F, Soranzo, Nicole, Speliotes, Elizabeth K, Stirrups, Kathleen, Thanopoulou, Anastasia, Traglia, Michela, Tsafantakis, Emmanouil, Javad, Sundas, Yanek, Lisa R, Becker, Diane M, Bis, Joshua C, Brown, James B, Ingelsson, Erik, Karter, Andrew J, Lorenzo, Carlos, Peloso, Gina M, Vaidya, Dhananjay, Varma, Rohit, Wagenknecht, Lynne E, Dedoussis, George, Deloukas, Panos, Franco, Oscar H, Gibbs, Richard A, Gudnason, Vilmundur, Hofman, Albert, Jansson, Jan-Håkan, Langenberg, Claudia, Launer, Lenore J, Levy, Daniel, Oostra, Ben A, Padmanabhan, Sandosh, Pankow, James S, Rudan, Igor, Schulze, Matthias B, Smith, Blair H, Walker, Mark, Wong, Tien Y, Laakso, Markku, Borecki, Ingrid B, van Duijn, Cornelia M, Waterworth, Dawn M, Loos, Ruth J.F., Meigs, James B, Scott, Robert A, Goodarzi, Mark O

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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche von Perry, John R. B., Ferreira, Teresa, Chasman, Daniel I., Esko, Tõnu, Thorleifsson, Gudmar, Albrecht, Eva, Ang, Wei Q., Corre, Tanguy, Cousminer, Diana L., Franceschini, Nora, Ganna, Andrea, Johnson, Andrew D., Kjellqvist, Sanela, Lunetta, Kathryn L., Porcu, Eleonora, Teumer, Alexander, Tikkanen, Emmi, Hottenga, Jouke-Jan, Pers, Tune H., Yerges-Armstrong, Laura M., Hua Zhao, Jing, Andrulis, Irene L., Anton-Culver, Hoda, Benitez, Javier, Blomqvist, Carl, Bolla, Manjeet K., Brenner, Hermann, Chang-Claude, Jenny, Chanock, Stephen, Chen, Jinhui, Chenevix-Trench, Georgia, Collée, J. Margriet, Davey Smith, George, Demerath, Ellen W., Dieffenbach, Aida K., Eriksson, Johan G., Flyger, Henrik, Franke, Lude, Gudbjartsson, Daniel F., Gudnason, Vilmundur, Guénel, Pascal, Guo, Suiqun, Hall, Per, Hartman, Catharina A., Heath, Andrew C., Hofman, Albert, Hooning, Maartje J., Hu, Frank B., Karasik, David, Kiel, Douglas P., Knight, Julia A., Kutalik, Zoltan, Lambrechts, Diether, Lindblom, Annika, Mägi, Reedik, Mannermaa, Arto, Martin, Nicholas G., Masson, Gisli, McArdle, Patrick F., Mihailov, Evelin, Nohr, Ellen A., Oostra, Ben A., Peacock, Munro, Peterlongo, Paolo, Peto, Julian, Postma, Dirkje S., Radice, Paolo, Rivadeneira, Fernando, Rose, Lynda M., Rudolph, Anja, Schlessinger, David, Sovio, Ulla, Tyrer, Jonathan, Vollenweider, Peter, Winqvist, Robert, Wolffenbuttel, Bruce H. R., Wright, Margaret J., Econs, Michael J., Loos, Ruth J. F., McCarthy, Mark I., Montgomery, Grant W., Rice, John P., Thorsteinsdottir, Unnur, van Duijn, Cornelia M., Alizadeh, Behrooz Z., Bergmann, Sven, Boerwinkle, Eric, Crisponi, Laura, Gasparini, Paolo, Gieger, Christian, Järvelin, Marjo-Riitta, Kraft, Peter, Ridker, Paul M., Snieder, Harold, Sørensen, Thorkild I. A., Spector, Tim D., Uitterlinden, André G., Zygmunt, Marek, Murray, Anna, Ong, Ken K.

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Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome von Balmus, Gabriel, Larrieu, Delphine, Barros, Ana C., Collins, Casey, Abrudan, Monica, Demir, Mukerrem, Geisler, Nicola J., Lelliott, Christopher J., White, Jacqueline K., Karp, Natasha A., Atkinson, James, Kirton, Andrea, Jacobsen, Matt, Clift, Dean, Rodriguez, Raphael, Adams, David J., Jackson, Stephen P.

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A genomic mutational constraint map using variation in 76,156 human genomes von Chen, Siwei, Francioli, Laurent C., Goodrich, Julia K., Collins, Ryan L., Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A., Vittal, Christopher, Gauthier, Laura D., Poterba, Timothy, Wilson, Michael W., Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T., Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O’Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R., Talkowski, Michael E., Rehm, Heidi L., Daly, Mark J., Tiao, Grace, Neale, Benjamin M., MacArthur, Daniel G., Karczewski, Konrad J.

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The minimal important difference of exercise tests in severe COPD von PUHAN, M. A, CHANDRA, D, MOSENIFAR, Z, RIES, A, MAKE, B, HANSEL, N. N, WISE, R. A, SCIURBA, F

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Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity von Cousminer, Diana L, Berry, Diane J, Timpson, Nicholas J, Ang, Wei, Thiering, Elisabeth, Byrne, Enda M, Taal, H Rob, Huikari, Ville, Bradfield, Jonathan P, Kerkhof, Marjan, Groen-Blokhuis, Maria M, Kreiner-Møller, Eskil, Marinelli, Marcella, Holst, Claus, Leinonen, Jaakko T, Perry, John R B, Surakka, Ida, Pietiläinen, Olli, Kettunen, Johannes, Anttila, Verneri, Kaakinen, Marika, Sovio, Ulla, Pouta, Anneli, Das, Shikta, Lagou, Vasiliki, Power, Chris, Prokopenko, Inga, Evans, David M, Kemp, John P, St Pourcain, Beate, Ring, Susan, Palotie, Aarno, Kajantie, Eero, Osmond, Clive, Lehtimäki, Terho, Viikari, Jorma S, Kähönen, Mika, Warrington, Nicole M, Lye, Stephen J, Palmer, Lyle J, Tiesler, Carla M T, Flexeder, Claudia, Montgomery, Grant W, Medland, Sarah E, Hofman, Albert, Hakonarson, Hakon, Guxens, Mònica, Bartels, Meike, Salomaa, Veikko, Murabito, Joanne M, Kaprio, Jaakko, Sørensen, Thorkild I A, Ballester, Ferran, Bisgaard, Hans, Boomsma, Dorret I, Koppelman, Gerard H, Grant, Struan F A, Jaddoe, Vincent W V, Martin, Nicholas G, Heinrich, Joachim, Pennell, Craig E, Raitakari, Olli T, Eriksson, Johan G, Smith, George Davey, Hyppönen, Elina, Järvelin, Marjo-Riitta, McCarthy, Mark I, Ripatti, Samuli, Widén, Elisabeth

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The contribution of hospital-acquired infections to the COVID-19 epidemic in England in the first half of 2020 von Knight, Gwenan M, Pham, Thi Mui, Stimson, James, Funk, Sebastian, Jafari, Yalda, Pople, Diane, Evans, Stephanie, Yin, Mo, Brown, Colin S, Bhattacharya, Alex, Hope, Russell, Semple, Malcolm G, Read, Jonathan M, Cooper, Ben S, Robotham, Julie V

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Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty von Cousminer, Diana L, Stergiakouli, Evangelia, Berry, Diane J, Ang, Wei, Groen-Blokhuis, Maria M, Körner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R B, Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J, Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kähönen, Mika, Viikari, Jorma, Lehtimäki, Terho, Middeldorp, Christel M, Hulshoff Pol, Hilleke E, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope, Bustamante, Mariona, Penninx, Brenda W J H, Murabito, Joanne, Torrent, Maties, Dedoussis, George V, Kiess, Wieland, Boomsma, Dorret I, Pennell, Craig E, Raitakari, Olli T, Hyppönen, Elina, Davey Smith, George, Ripatti, Samuli, McCarthy, Mark I, Widén, Elisabeth

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