Proteomics reveals a core molecular response of Pseudomonas putida F1 to acute chromate challenge von Thompson, Dorothea K, Chourey, Karuna, Wickham, Gene S, Thieman, Stephanie B, VerBerkmoes, Nathan C, Zhang, Bing, McCarthy, Andrea T, Rudisill, Matt A, Shah, Manesh, Hettich, Robert L

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Common genetic variation and the control of HIV-1 in humans von Fellay, Jacques, Ge, Dongliang, Shianna, Kevin V, Colombo, Sara, Ledergerber, Bruno, Cirulli, Elizabeth T, Urban, Thomas J, Zhang, Kunlin, Gumbs, Curtis E, Smith, Jason P, Castagna, Antonella, Cozzi-Lepri, Alessandro, De Luca, Andrea, Easterbrook, Philippa, Günthard, Huldrych F, Mallal, Simon, Mussini, Cristina, Dalmau, Judith, Martinez-Picado, Javier, Miro, José M, Obel, Niels, Wolinsky, Steven M, Martinson, Jeremy J, Detels, Roger, Margolick, Joseph B, Jacobson, Lisa P, Descombes, Patrick, Antonarakis, Stylianos E, Beckmann, Jacques S, O'Brien, Stephen J, Letvin, Norman L, McMichael, Andrew J, Haynes, Barton F, Carrington, Mary, Feng, Sheng, Telenti, Amalio, Goldstein, David B

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Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes von Zhou, Xueya, Feliciano, Pamela, Shu, Chang, Wang, Tianyun, Astrovskaya, Irina, Hall, Jacob B., Obiajulu, Joseph U., Wright, Jessica R., Murali, Shwetha C., Xu, Simon Xuming, Brueggeman, Leo, Thomas, Taylor R., Marchenko, Olena, Fleisch, Christopher, Barns, Sarah D., Snyder, LeeAnne Green, Han, Bing, Chang, Timothy S., Turner, Tychele N., Harvey, William T., Nishida, Andrew, O’Roak, Brian J., Geschwind, Daniel H., Michaelson, Jacob J., Volfovsky, Natalia, Eichler, Evan E., Shen, Yufeng, Chung, Wendy K.

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Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1 von Winkelmann, Juliane, Czamara, Darina, Schormair, Barbara, Knauf, Franziska, Schulte, Eva C, Trenkwalder, Claudia, Dauvilliers, Yves, Polo, Olli, Högl, Birgit, Berger, Klaus, Fuhs, Andrea, Gross, Nadine, Stiasny-Kolster, Karin, Oertel, Wolfgang, Bachmann, Cornelius G, Paulus, Walter, Xiong, Lan, Montplaisir, Jacques, Rouleau, Guy A, Fietze, Ingo, Vávrová, Jana, Kemlink, David, Sonka, Karel, Nevsimalova, Sona, Lin, Siong-Chi, Wszolek, Zbigniew, Vilariño-Güell, Carles, Farrer, Matthew J, Gschliesser, Viola, Frauscher, Birgit, Falkenstetter, Tina, Poewe, Werner, Allen, Richard P, Earley, Christopher J, Ondo, William G, Le, Wei-Dong, Spieler, Derek, Kaffe, Maria, Zimprich, Alexander, Kettunen, Johannes, Perola, Markus, Silander, Kaisa, Cournu-Rebeix, Isabelle, Francavilla, Marcella, Fontenille, Claire, Fontaine, Bertrand, Vodicka, Pavel, Prokisch, Holger, Lichtner, Peter, Peppard, Paul, Faraco, Juliette, Mignot, Emmanuel, Gieger, Christian, Illig, Thomas, Wichmann, H-Erich, Müller-Myhsok, Bertram, Meitinger, Thomas

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A qualitative review of challenges in recruitment and retention in obstetrics and gynecology in Ireland: The consultants' solution based perspective von McCarthy, Claire M, Meaney, Sarah, O'Sullivan, Suzanne, Horgan, Mary, Bennett, Deirdre, O'Donoghue, Keelin

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Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer von Chi, Kim N, Agarwal, Neeraj, Bjartell, Anders, Chung, Byung Ha, Pereira de Santana Gomes, Andrea J, Given, Robert, Juárez Soto, Álvaro, Merseburger, Axel S, Özgüroğlu, Mustafa, Uemura, Hirotsugu, Ye, Dingwei, Deprince, Kris, Naini, Vahid, Li, Jinhui, Cheng, Shinta, Yu, Margaret K, Zhang, Ke, Larsen, Julie S, McCarthy, Sharon, Chowdhury, Simon

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The mutational constraint spectrum quantified from variation in 141,456 humans von Karczewski, Konrad J., Francioli, Laurent C., Tiao, Grace, Cummings, Beryl B., Alföldi, Jessica, Wang, Qingbo, Collins, Ryan L., Laricchia, Kristen M., Ganna, Andrea, Birnbaum, Daniel P., Gauthier, Laura D., Brand, Harrison, Solomonson, Matthew, Watts, Nicholas A., Rhodes, Daniel, Singer-Berk, Moriel, England, Eleina M., Seaby, Eleanor G., Kosmicki, Jack A., Walters, Raymond K., Tashman, Katherine, Farjoun, Yossi, Banks, Eric, Poterba, Timothy, Wang, Arcturus, Seed, Cotton, Whiffin, Nicola, Chong, Jessica X., Samocha, Kaitlin E., Pierce-Hoffman, Emma, Zappala, Zachary, O’Donnell-Luria, Anne H., Minikel, Eric Vallabh, Weisburd, Ben, Lek, Monkol, Ware, James S., Vittal, Christopher, Armean, Irina M., Bergelson, Louis, Cibulskis, Kristian, Connolly, Kristen M., Covarrubias, Miguel, Donnelly, Stacey, Ferriera, Steven, Gabriel, Stacey, Gentry, Jeff, Gupta, Namrata, Jeandet, Thibault, Kaplan, Diane, Llanwarne, Christopher, Munshi, Ruchi, Novod, Sam, Petrillo, Nikelle, Roazen, David, Ruano-Rubio, Valentin, Saltzman, Andrea, Schleicher, Molly, Soto, Jose, Tibbetts, Kathleen, Tolonen, Charlotte, Wade, Gordon, Talkowski, Michael E., Neale, Benjamin M., Daly, Mark J., MacArthur, Daniel G.

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Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial von Young, Paul, Bailey, Michael, Beasley, Richard, Henderson, Seton, Mackle, Diane, McArthur, Colin, McGuinness, Shay, Mehrtens, Jan, Myburgh, John, Psirides, Alex, Reddy, Sumeet, Bellomo, Rinaldo

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Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma von Richardson, Paul G., Jacobus, Susanna J., Weller, Edie A., Hassoun, Hani, Lonial, Sagar, Raje, Noopur S., Medvedova, Eva, McCarthy, Philip L., Libby, Edward N., Voorhees, Peter M., Orlowski, Robert Z., Anderson, Larry D., Zonder, Jeffrey A., Milner, Carter P., Gasparetto, Cristina, Agha, Mounzer E., Khan, Abdullah M., Hurd, David D., Gowin, Krisstina, Kamble, Rammurti T., Jagannath, Sundar, Nathwani, Nitya, Alsina, Melissa, Cornell, R. Frank, Hashmi, Hamza, Campagnaro, Erica L., Andreescu, Astrid C., Gentile, Teresa, Liedtke, Michaela, Godby, Kelly N., Cohen, Adam D., Openshaw, Thomas H., Pasquini, Marcelo C., Giralt, Sergio A., Kaufman, Jonathan L., Yee, Andrew J., Scott, Emma, Torka, Pallawi, Foley, Amy, Fulciniti, Mariateresa, Hebert, Kyle, Samur, Mehmet K., Masone, Kelly, Maglio, Michelle E., Zeytoonjian, Andrea A., Nadeem, Omar, Schlossman, Robert L., Laubach, Jacob P., Paba-Prada, Claudia, Ghobrial, Irene M., Perrot, Aurore, Moreau, Philippe, Avet-Loiseau, Hervé, Attal, Michel, Anderson, Kenneth C., Munshi, Nikhil C.

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A reference map of potential determinants for the human serum metabolome von Bar, Noam, Korem, Tal, Weissbrod, Omer, Zeevi, David, Rothschild, Daphna, Leviatan, Sigal, Kosower, Noa, Lotan-Pompan, Maya, Weinberger, Adina, Le Roy, Caroline I., Menni, Cristina, Visconti, Alessia, Falchi, Mario, Spector, Tim D., Adamski, Jerzy, Franks, Paul W., Pedersen, Oluf, Segal, Eran

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Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression von Cuomo, Anna S. E., Seaton, Daniel D., McCarthy, Davis J., Martinez, Iker, Bonder, Marc Jan, Garcia-Bernardo, Jose, Amatya, Shradha, Madrigal, Pedro, Isaacson, Abigail, Buettner, Florian, Knights, Andrew, Natarajan, Kedar Nath, Vallier, Ludovic, Marioni, John C., Chhatriwala, Mariya, Stegle, Oliver

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Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis von Baeten, Dominique, Sieper, Joachim, Braun, Jürgen, Baraliakos, Xenofon, Dougados, Maxime, Emery, Paul, Deodhar, Atul, Porter, Brian, Martin, Ruvie, Andersson, Mats, Mpofu, Shephard, Richards, Hanno B

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Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome von Balmus, Gabriel, Larrieu, Delphine, Barros, Ana C., Collins, Casey, Abrudan, Monica, Demir, Mukerrem, Geisler, Nicola J., Lelliott, Christopher J., White, Jacqueline K., Karp, Natasha A., Atkinson, James, Kirton, Andrea, Jacobsen, Matt, Clift, Dean, Rodriguez, Raphael, Adams, David J., Jackson, Stephen P.

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Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial von Smolen, Josef S, Prof, Beaulieu, Andre, MD, Rubbert-Roth, Andrea, MD, Ramos-Remus, Cesar, Prof, Rovensky, Josef, Prof, Alecock, Emma, MSc, Woodworth, Thasia, MD, Alten, Rieke, MD

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An integrated map of genetic variation from 1,092 human genomes von Abecasis, Goncalo R, Auton, Adam, Brooks, Lisa D, DePristo, Mark A, Durbin, Richard M, Handsaker, Robert E, Kang, Hyun Min, Marth, Gabor T, McVean, Gil A

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Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer: Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study von Chi, Kim N, Chowdhury, Simon, Bjartell, Anders, Chung, Byung Ha, Pereira de Santana Gomes, Andrea J, Given, Robert, Juárez, Alvaro, Merseburger, Axel S, Özgüroğlu, Mustafa, Uemura, Hirotsugu, Ye, Dingwei, Brookman-May, Sabine, Mundle, Suneel D, McCarthy, Sharon A, Larsen, Julie S, Sun, Weili, Bevans, Katherine B, Zhang, Ke, Bandyopadhyay, Nibedita, Agarwal, Neeraj

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Teplizumab and β-Cell Function in Newly Diagnosed Type 1 Diabetes von Ramos, Eleanor L, Dayan, Colin M, Chatenoud, Lucienne, Sumnik, Zdenek, Simmons, Kimber M, Szypowska, Agnieszka, Gitelman, Stephen E, Knecht, Laura A, Niemoeller, Elisabeth, Tian, Wei, Herold, Kevan C

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Genetic studies of body mass index yield new insights for obesity biology von Croteau-Chonka, Damien C., Wood, Andrew R., Absher, Devin, Bragg-Gresham, Jennifer L., Buyske, Steven, Feitosa, Mary F., Mangino, Massimo, Mateo Leach, Irene, Palmer, Cameron D., Pasko, Dorota, Ju Sung, Yun, Teumer, Alexander, van der Laan, Sander W., Ärnlöv, Johan, Berne, Christian, Bonnycastle, Lori L., Bruinenberg, Marcel, Ida Chen, Yii-Der, de Craen, Anton J. M., Delgado, Graciela, Fraser, Ross M., Grönberg, Henrik, Gusto, Gaëlle, Hassinen, Maija, Jeff, Janina M., Kinnunen, Leena, Kratzer, Wolfgang, Lee, Nanette R., Lichtner, Peter, Lind, Lars, Sin Lo, Ken, Lorbeer, Roberto, Mahajan, Anubha, Milani, Lili, Monda, Keri L., Nolte, Ilja M., Pilz, Stefan, Rettig, Rainer, Ripke, Stephan, Sanna, Serena, Schumacher, Fredrick R., Scott, William R., Smolonska, Joanna, Stirrups, Kathleen, Stringham, Heather M., Uh, Hae-Won, Vandenput, Liesbeth, Warren, Helen R., Brennan, Eoin P., Drong, Alexander W., Min, Josine L., Okada, Yukinori, Takahashi, Atsushi, Tanaka, Toshihiro, Westra, Harm-Jan, Campbell, Harry, den Ruijter, Hester M., Erbel, Raimund, Farrall, Martin, Franco, Oscar H., Gejman, Pablo V., Gieger, Christian, Gottesman, Omri, Hingorani, Aroon D., Hyppönen, Elina, Jarvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Johansen, Berit, Kooperberg, Charles, Langenberg, Claudia, Postma, Dirkje S., Price, Jackie F., Rao, D. C., Rioux, John D., Schunkert, Heribert, Shuldiner, Alan R., Strauch, Konstantin, Tremblay, Angelo, Adair, Linda S., de Bakker, Paul I. W., Ferrucci, Luigi, Hveem, Kristian, März, Winfried, Munroe, Patricia B., Njølstad, Inger, Palmer, Colin N. A., Pedersen, Nancy L., Pérusse, Louis, Saaristo, Timo E., Saleheen, Danish, Sattar, Naveed, Eline Slagboom, P., Tuomilehto, Jaakko, Deloukas, Panos, Stefansson, Kari, van Duijn, Cornelia M., Willer, Cristen J., Ingelsson, Erik, Hirschhorn, Joel N., Loos, Ruth J. F.

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2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient manage... von Calkins, Hugh, Kuck, Karl Heinz, Cappato, Riccardo, Brugada, Josep, Camm, A John, Chen, Shih-Ann, Crijns, Harry J G, Damiano, Jr, Ralph J, Davies, D Wyn, DiMarco, John, Edgerton, James, Ellenbogen, Kenneth, Ezekowitz, Michael D, Haines, David E, Haissaguerre, Michel, Hindricks, Gerhard, Iesaka, Yoshito, Jackman, Warren, Jalife, José, Jais, Pierre, Kalman, Jonathan, Keane, David, Kim, Young-Hoon, Kirchhof, Paulus, Klein, George, Kottkamp, Hans, Kumagai, Koichiro, Lindsay, Bruce D, Mansour, Moussa, Marchlinski, Francis E, McCarthy, Patrick M, Mont, J Lluis, Morady, Fred, Nademanee, Koonlawee, Nakagawa, Hiroshi, Natale, Andrea, Nattel, Stanley, Packer, Douglas L, Pappone, Carlo, Prystowsky, Eric, Raviele, Antonio, Reddy, Vivek, Ruskin, Jeremy N, Shemin, Richard J, Tsao, Hsuan-Ming, Wilber, David

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Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma: The PROPPR Randomized Clinical Trial von Holcomb, John B, Tilley, Barbara C, Baraniuk, Sarah, Fox, Erin E, Wade, Charles E, Podbielski, Jeanette M, del Junco, Deborah J, Brasel, Karen J, Bulger, Eileen M, Callcut, Rachael A, Cohen, Mitchell Jay, Cotton, Bryan A, Fabian, Timothy C, Inaba, Kenji, Kerby, Jeffrey D, Muskat, Peter, O’Keeffe, Terence, Rizoli, Sandro, Robinson, Bryce R. H, Scalea, Thomas M, Schreiber, Martin A, Stein, Deborah M, Weinberg, Jordan A, Callum, Jeannie L, Hess, John R, Matijevic, Nena, Miller, Christopher N, Pittet, Jean-Francois, Hoyt, David B, Pearson, Gail D, Leroux, Brian, van Belle, Gerald

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