Base editing of haematopoietic stem cells rescues sickle cell disease in mice von Newby, Gregory A., Yen, Jonathan S., Woodard, Kaitly J., Mayuranathan, Thiyagaraj, Lazzarotto, Cicera R., Li, Yichao, Sheppard-Tillman, Heather, Porter, Shaina N., Yao, Yu, Mayberry, Kalin, Everette, Kelcee A., Jang, Yoonjeong, Podracky, Christopher J., Thaman, Elizabeth, Lechauve, Christophe, Sharma, Akshay, Henderson, Jordana M., Richter, Michelle F., Zhao, Kevin T., Miller, Shannon M., Wang, Tina, Koblan, Luke W., McCaffrey, Anton P., Tisdale, John F., Kalfa, Theodosia A., Pruett-Miller, Shondra M., Tsai, Shengdar Q., Weiss, Mitchell J., Liu, David R.

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Small RNA Library Preparation Method for Next-Generation Sequencing Using Chemical Modifications to Prevent Adapter Dimer Formation von Shore, Sabrina, Henderson, Jordana M, Lebedev, Alexandre, Salcedo, Michelle P, Zon, Gerald, McCaffrey, Anton P, Paul, Natasha, Hogrefe, Richard I

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Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes von Graff, Joel W., Dickson, Anne M., Clay, Gwendolyn, McCaffrey, Anton P., Wilson, Mary E.

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Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification von Vaidyanathan, Sriram, Azizian, Krist T., Haque, A.K.M. Ashiqul, Henderson, Jordana M., Hendel, Ayal, Shore, Sabrina, Antony, Justin S., Hogrefe, Richard I., Kormann, Michael S.D., Porteus, Matthew H., McCaffrey, Anton P.

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Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope von Jiang, Tingting, Henderson, Jordana M., Coote, Kevin, Cheng, Yi, Valley, Hillary C., Zhang, Xiao-Ou, Wang, Qin, Rhym, Luke H., Cao, Yueying, Newby, Gregory A., Bihler, Hermann, Mense, Martin, Weng, Zhiping, Anderson, Daniel G., McCaffrey, Anton P., Liu, David R., Xue, Wen

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Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors von Dassie, Justin P, Thomas, Gregory S, Thiel, Kristina W, Meyerholz, David K, McCaffrey, Anton P, McNamara, James O, Whitaker, Ryan M, Stockdale, Katie R, Liu, Xiu-ying, Giangrande, Paloma H

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Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs von Cradick, Thomas J, Keck, Kathy, Bradshaw, Shannon, Jamieson, Andrew C, McCaffrey, Anton P

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Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture von Bandyopadhyay, Sarmistha, Friedman, Robin C., Marquez, Rebecca T., Keck, Kathy, Kong, Benjamin, Icardi, Michael S., Brown, Kyle E., Burge, Christopher B., Schmidt, Warren N., Wang, Yulei, McCaffrey, Anton P.

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ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites von Cradick, Thomas J, Ambrosini, Giovanna, Iseli, Christian, Bucher, Philipp, McCaffrey, Anton P

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In vivo activity of nuclease-resistant siRNAs von Layzer, Juliana M, McCaffrey, Anton P, Tanner, Alice K, Huang, Zan, Kay, Mark A, Sullenger, Bruce A

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Inhibition of hepatitis B virus in mice by RNA interference von Kay, Mark A, McCaffrey, Anton P, Nakai, Hiroyuki, Pandey, Kusum, Huang, Zan, Salazar, Felix H, Xu, Hui, Wieland, Stefan F, Marion, Patricia L

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Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects von Ramirez, Cherie L, Certo, Michael T, Mussolino, Claudio, Goodwin, Mathew J, Cradick, Thomas J, McCaffrey, Anton P, Cathomen, Toni, Scharenberg, Andrew M, Joung, J Keith

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Efficient Production of On-Target Reads for Small RNA Sequencing of Single Cells Using Modified Adapters von Khnouf, Ruba, Shore, Sabrina, Han, Crystal M, Henderson, Jordana M, Munro, Sarah A, McCaffrey, Anton P, Shintaku, Hirofumi, Santiago, Juan G

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Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans von Marquez, Rebecca T, Bandyopadhyay, Sarmistha, Wendlandt, Erik B, Keck, Kathy, Hoffer, Brandon A, Icardi, Michael S, Christensen, Randolph N, Schmidt, Warren N, McCaffrey, Anton P

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Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: Mechanism for the antiviral effects of heme oxygenase? von Zhu, Zhaowen, Wilson, Anne T., Luxon, Bruce A., Brown, Kyle E., Mathahs, M. Meleah, Bandyopadhyay, Sarmistha, McCaffrey, Anton P., Schmidt, Warren N.

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The role of MicroRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation von Wendlandt, Erik B, Graff, Joel W, Gioannini, Theresa L, McCaffrey, Anton P, Wilson, Mary E

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CleanTag Adapters Improve Small RNA Next-Generation Sequencing Library Preparation by Reducing Adapter Dimers von Shore, Sabrina, Henderson, Jordana M., McCaffrey, Anton P.

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RNA interference in adult mice von McCaffrey, Anton P, Meuse, Leonard, Pham, Thu-Thao T, Conklin, Douglas S, Hannon, Gregory J, Kay, Mark A

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RNA Interference Inhibitors of Hepatitis B Virus von McCaffrey, Anton P.

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In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs von Urak, Kevin T., Shore, Sabrina, Rockey, William M., Chen, Shi-Jie, McCaffrey, Anton P., Giangrande, Paloma H.

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