Abstract 251: Thrombolysis, DAPT, and Anticoagulation Administration in the Region Around Amarillo, Texas, in Patients with ST Elevation Myocardial Infarction From 2013-2016 von McMaster, Kelly S, Wang, Grace C, McBrayer, Michael A, Chatterjee, Totini S, Patel, Manish, Urban, Steven, Brabham, David G

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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate von Chakraborty, Abhishek A., Laukka, Tuomas, Myllykoski, Matti, Ringel, Alison E., Booker, Matthew A., Tolstorukov, Michael Y., Meng, Yuzhong Jeff, Meier, Samuel R., Jennings, Rebecca B., Creech, Amanda L., Herbert, Zachary T., McBrayer, Samuel K., Olenchock, Benjamin A., Jaffe, Jacob D., Haigis, Marcia C., Beroukhim, Rameen, Signoretti, Sabina, Koivunen, Peppi, Kaelin, William G.

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GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis von Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.

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De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma von Shi, Diana D, Savani, Milan R, Levitt, Michael M, Wang, Adam C, Endress, Jennifer E, Bird, Cylaina E, Buehler, Joseph, Stopka, Sylwia A, Regan, Michael S, Lin, Yu-Fen, Puliyappadamba, Vinesh T, Gao, Wenhua, Khanal, Januka, Evans, Laura, Lee, Joyce H, Guo, Lei, Xiao, Yi, Xu, Min, Huang, Bofu, Jennings, Rebecca B, Bonal, Dennis M, Martin-Sandoval, Misty S, Dang, Tammie, Gattie, Lauren C, Cameron, Amy B, Lee, Sungwoo, Asara, John M, Kornblum, Harley I, Mak, Tak W, Looper, Ryan E, Nguyen, Quang-De, Signoretti, Sabina, Gradl, Stefan, Sutter, Andreas, Jeffers, Michael, Janzer, Andreas, Lehrman, Mark A, Zacharias, Lauren G, Mathews, Thomas P, Losman, Julie-Aurore, Richardson, Timothy E, Cahill, Daniel P, DeBerardinis, Ralph J, Ligon, Keith L, Xu, Lin, Ly, Peter, Agar, Nathalie Y R, Abdullah, Kalil G, Harris, Isaac S, Kaelin, Jr, William G, McBrayer, Samuel K

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Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice von Rao, Mala V, McBrayer, Mary Kate, Campbell, Jabbar, Kumar, Asok, Hashim, Audrey, Sershen, Henry, Stavrides, Philip H, Ohno, Masuo, Hutton, Michael, Nixon, Ralph A

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A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma von Pal, Sharmistha, Kaplan, Jakub P., Nguyen, Huy, Stopka, Sylwia A., Savani, Milan R., Regan, Michael S., Nguyen, Quang-De, Jones, Kristen L., Moreau, Lisa A., Peng, Jingyu, Dipiazza, Marina G., Perciaccante, Andrew J., Zhu, Xiaoting, Hunsel, Bradley R., Liu, Kevin X., Alexandrescu, Sanda, Drissi, Rachid, Filbin, Mariella G., McBrayer, Samuel K., Agar, Nathalie Y.R., Chowdhury, Dipanjan, Haas-Kogan, Daphne A.

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Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication von Clark, Jeremy L, Hollecker, Laurent, Mason, J. Christian, Stuyver, Lieven J, Tharnish, Phillip M, Lostia, Stefania, McBrayer, Tamara R, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J, Furman, Phillip A, Stec, Wojciech J, Patterson, Steven E, Pankiewicz, Krzysztof W

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Forebrain-Specific Loss of BMPRII in Mice Reduces Anxiety and Increases Object Exploration von McBrayer, Zofeyah L, Dimova, Jiva, Pisansky, Marc T, Sun, Mu, Beppu, Hideyuki, Gewirtz, Jonathan C, O'Connor, Michael B

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Calendar aging of silicon-containing batteries von McBrayer, Josefine D., Rodrigues, Marco-Tulio F., Schulze, Maxwell C., Abraham, Daniel P., Apblett, Christopher A., Bloom, Ira, Carroll, Gerard Michael, Colclasure, Andrew M., Fang, Chen, Harrison, Katharine L., Liu, Gao, Minteer, Shelley D., Neale, Nathan R., Veith, Gabriel M., Johnson, Christopher S., Vaughey, John T., Burrell, Anthony K., Cunningham, Brian

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Establishment of patient-derived organoid models of lower-grade glioma von Abdullah, Kalil G, Bird, Cylaina E, Buehler, Joseph D, Gattie, Lauren C, Savani, Milan R, Sternisha, Alex C, Xiao, Yi, Levitt, Michael M, Hicks, William H, Li, Wenhao, Ramirez, Denise M O, Patel, Toral, Garzon-Muvdi, Tomas, Barnett, Samuel, Zhang, Gao, Ashley, David M, Hatanpaa, Kimmo J, Richardson, Timothy E, McBrayer, Samuel K

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Prothoracicotropic Hormone Regulates Developmental Timing and Body Size in Drosophila von McBrayer, Zofeyah, Ono, Hajime, Shimell, MaryJane, Parvy, Jean-Philippe, Beckstead, Robert B., Warren, James T., Thummel, Carl S., Dauphin-Villemant, Chantal, Gilbert, Lawrence I., O'Connor, Michael B.

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Catalytic fast pyrolysis of biomass: the reactions of water and aromatic intermediates produces phenols von Mukarakate, Calvin, McBrayer, Josefine D, Evans, Tabitha J, Budhi, Sridhar, Robichaud, David J, Iisa, Kristiina, ten Dam, Jeroen, Watson, Michael J, Baldwin, Robert M, Nimlos, Mark R

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EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation von Guo, Gao, Gong, Ke, Beckley, Nicole, Zhang, Yue, Yang, Xiaoyao, Chkheidze, Rati, Hatanpaa, Kimmo J., Garzon-Muvdi, Tomas, Koduru, Prasad, Nayab, Arifa, Jenks, Jennifer, Sathe, Adwait Amod, Liu, Yan, Xing, Chao, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Mukherjee, Bipasha, Burma, Sandeep, Wohlfeld, Bryan, Patel, Toral, Mickey, Bruce, Abdullah, Kalil, Youssef, Michael, Pan, Edward, Gerber, David E., Tian, Shulan, Sarkaria, Jann N., McBrayer, Samuel K., Zhao, Dawen, Habib, Amyn A.

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Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture von STUYVER, Lieven J, WHITAKER, Tony, RACHAKONDA, Suguna, WATANABE, Kyoichi A, OTTO, Michael J, SCHINAZI, Raymond F, MCBRAYER, Tamara R, HERNANDEZ-SANTIAGO, Brenda I, LOSTIA, Stefania, THARNISH, Phillip M, RAMESH, Mangala, CHU, Chung K, JORDAN, Robert, JUNXING SHI

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Extracellular vesicles restrict dengue virus fusion in Aedes aegypti cells von Freitas, Megan N., Marten, Andrew D., Moore, Gavin A., Tree, Maya O., McBrayer, Sean P., Conway, Michael J.

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(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers von Gunn, Kathryn, Myllykoski, Matti, Cao, John Z, Ahmed, Manna, Huang, Bofu, Rouaisnel, Betty, Diplas, Bill H, Levitt, Michael M, Looper, Ryan, Doench, John G, Ligon, Keith L, Kornblum, Harley I, McBrayer, Samuel K, Yan, Hai, Duy, Cihangir, Godley, Lucy A, Koivunen, Peppi, Losman, Julie-Aurore

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Capsaicin-treated bait is ineffective in deterring non-target mammals from trap disturbance during invasive lizard control von McBrayer, Lance D., Haro, Daniel, Brennan, Michael, Falk, Bryan G., Yackel Adams, Amy A.

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Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions von Miller, Julie J, Gonzalez Castro, L Nicolas, McBrayer, Samuel, Weller, Michael, Cloughesy, Timothy, Portnow, Jana, Andronesi, Ovidiu, Barnholtz-Sloan, Jill S, Baumert, Brigitta G, Berger, Mitchell S, Bi, Wenya Linda, Bindra, Ranjit, Cahill, Daniel P, Chang, Susan M, Costello, Joseph F, Horbinski, Craig, Huang, Raymond Y, Jenkins, Robert B, Ligon, Keith L, Mellinghoff, Ingo K, Nabors, L Burt, Platten, Michael, Reardon, David A, Shi, Diana D, Schiff, David, Wick, Wolfgang, Yan, Hai, von Deimling, Andreas, van den Bent, Martin, Kaelin, William G, Wen, Patrick Y

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Semi-Automated Computational Assessment of Cancer Organoid Viability Using Rapid Live-Cell Microscopy von Buehler, Joseph D, Bird, Cylaina E, Savani, Milan R, Gattie, Lauren C, Hicks, William H, Levitt, Michael M, El Shami, Mohamad, Hatanpaa, Kimmo J, Richardson, Timothy E, McBrayer, Samuel K, Abdullah, Kalil G

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Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms von McBrayer, Samuel K, Yarrington, Michael, Qian, Jun, Feng, Gang, Shanmugam, Mala, Gandhi, Varsha, Krett, Nancy L, Rosen, Steven T

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