Phase II, Open-Label Study Evaluating the Activity of Imatinib in Treating Life-Threatening Malignancies Known to Be Associated with Imatinib-Sensitive Tyrosine Kinases von Heinrich, Michael C, Joensuu, Heikki, Demetri, George D, Corless, Christopher L, Apperley, Jane, Fletcher, Jonathan A, Soulieres, Denis, Dirnhofer, Stephan, Harlow, Amy, Town, Ajia, McKinley, Arin, Supple, Shane G, Seymour, John, Di Scala, Lilla, van Oosterom, Allan, Herrmann, Richard, Nikolova, Zariana, McArthur, And Grant

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Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation von Chapman, Paul B, Hauschild, Axel, Robert, Caroline, Haanen, John B, Ascierto, Paolo, Larkin, James, Dummer, Reinhard, Garbe, Claus, Testori, Alessandro, Maio, Michele, Hogg, David, Lorigan, Paul, Lebbe, Celeste, Jouary, Thomas, Schadendorf, Dirk, Ribas, Antoni, O'Day, Steven J, Sosman, Jeffrey A, Kirkwood, John M, Eggermont, Alexander M.M, Dreno, Brigitte, Nolop, Keith, Li, Jiang, Nelson, Betty, Hou, Jeannie, Lee, Richard J, Flaherty, Keith T, McArthur, and Grant A

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Melanoma staging: Evidence‐based changes in the American Joint Committee on Cancer eighth edition cancer staging manual von Gershenwald, Jeffrey E., Scolyer, Richard A., Hess, Kenneth R., Sondak, Vernon K., Long, Georgina V., Ross, Merrick I., Lazar, Alexander J., Faries, Mark B., Kirkwood, John M., McArthur, Grant A., Haydu, Lauren E., Eggermont, Alexander M. M., Flaherty, Keith T., Balch, Charles M., Thompson, John F., Gershenwald, Jeffrey E., Scolyer, Richard A., Atkins, Michael B., Balch, Charles M., Barnhill, Raymond L., Bilimoria, Karl Y., Buzaid, Antonio C., Byrd, David R., Cochran, Alistair J., Eggermont, Alexander M. M., Elder, David E., Faries, Mark B., Flaherty, Keith T., Garbe, Claus, Gardner, Julie M., Gimotty, Phyllis A., Halpern, Allan C., Haydu, Lauren E., Hess, Kenneth R., Johnson, Timothy M., Kirkwood, John M., Lazar, Alexander J., Lee, Anne W. M., Long, Georgina V., McArthur, Grant A., Mihm Jr, Martin C., Prieto, Victor G., Ross, Merrick I., Sober, Arthur J., Sondak, Vernon K., Thompson, John F., Wong, Sandra L., Delman, Keith A., Santinami, Mario, Maurichi, Andrea, Nagore, Eduardo, Faries, Mark B., Thompson, John F., Scolyer, Richard A., McArthur, Grant A., Gyorki, David E., Henderson, Michael, Stratigos, Alexander J., Gogas, Helen, Gershenwald, Jeffrey E., Haydu, Lauren E., Rossi, Carlo Riccardo, Sommariva, Antonio

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Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium von Amaria, Rodabe N, Menzies, Alexander M, Burton, Elizabeth M, Scolyer, Richard A, Tetzlaff, Michael T, Antdbacka, Robert, Ariyan, Charlotte, Bassett, Roland, Carter, Brett, Daud, Adil, Faries, Mark, Fecher, Leslie A, Flaherty, Keith T, Gershenwald, Jeffrey E, Hamid, Omid, Hong, Angela, Kirkwood, John M, Lo, Serigne, Margolin, Kim, Messina, Jane, Postow, Michael A, Rizos, Helen, Ross, Merrick I, Rozeman, Elisa A, Saw, Robyn P M, Sondak, Vernon, Sullivan, Ryan J, Taube, Janis M, Thompson, John F, van de Wiel, Bart A, Eggermont, Alexander M, Davies, Michael A, Andrews, Miles C, Berry, Donald A, Block, Matthew S, Boland, Genevieve M, Bollin, Kathryn B, Carlino, Matteo S, Carvajal, Richard D, Cohen, Jonathan, Davar, Diwakar, Delman, Keith A, Dummer, Reinhard, Farwell, Michael D, Fisher, David E, Fusi, Alberto, Glitza, Isabella C, de Gruijl, Tanja D, Gyorki, David E, Hauschild, Axel, Hieken, Tina J, Larkin, James, Lawson, David H, Lebbe, Celeste, Lee, Jeffrey E, Lowe, Michael C, Luke, Jason J, McArthur, Grant A, McDermott, David F, McQuade, Jennifer L, Mitchell, Tara C, Petrella, Teresa M, Prieto, Peter A, Puzanov, Igor, Robert, Caroline, Salama, April K, Sandhu, Shaneen, Schadendorf, Dirk, Shoushtari, Alexander N, Sosman, Jeffrey A, Swetter, Susan M, Tanabe, Ken K, Turajlic, Samra, Tyler, Douglas S, Woodman, Scott E, Wright, Frances C, Zager, Jonathan S, Ascierto, Paolo A, Spillane, Andrew J, van Akkooi, Alexander C J, Wargo, Jennifer A, Blank, Christian U, Tawbi, Hussein A, Long, Georgina V

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Long-Term Survival after Complete Surgical Resection and Adjuvant Immunotherapy for Distant Melanoma Metastases von Faries, Mark B., Mozzillo, Nicola, Kashani-Sabet, Mohammed, Thompson, John F., Kelley, Mark C., DeConti, Ronald C., Lee, Jeffrey E., Huth, James F., Wagner, Jeffrey, Dalgleish, Angus, Pertschuk, Daniel, Nardo, Christopher, Stern, Stacey, Elashoff, Robert, Gammon, Guy, Morton, Donald L.

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Combination Immune Checkpoint Inhibition: Is First Line Best? von McArthur, Grant A

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The Cell-Cycle Regulator CDK4: An Emerging Therapeutic Target in Melanoma von SHEPPARD, Karen E, MCARTHUR, Grant A

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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53 von Bywater, Megan J., Poortinga, Gretchen, Sanij, Elaine, Hein, Nadine, Peck, Abigail, Cullinane, Carleen, Wall, Meaghan, Cluse, Leonie, Drygin, Denis, Anderes, Kenna, Huser, Nanni, Proffitt, Chris, Bliesath, Joshua, Haddach, Mustapha, Schwaebe, Michael K., Ryckman, David M., Rice, William G., Schmitt, Clemens, Lowe, Scott W., Johnstone, Ricky W., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.

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Targeting Oncogenic Drivers and the Immune System in Melanoma von MCARTHUR, Grant A, RIBAS, Antoni

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Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor von KIM, Kevin B, KEFFORD, Richard, GONZALEZ, Rene, OTT, Patrick A, LONG, Georgina V, GARDNER, Olivia S, OUELLET, Daniele, YANMEI XU, DEMARINI, Douglas J, LE, Ngocdiep T, PATEL, Kiran, LEWIS, Karl D, PAVLICK, Anna C, INFANTE, Jeffrey R, RIBAS, Antoni, SOSMAN, Jeffrey A, FECHER, Leslie A, MILLWARD, Michael, MCARTHUR, GrantA, HWU, Patrick

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An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp von Ahmad, Shehryar, Wang, Boyuan, Walker, Matthew D., Tran, Hiu-Ki R., Stogios, Peter J., Savchenko, Alexei, Grant, Robert A., McArthur, Andrew G., Laub, Michael T., Whitney, John C.

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Dermatofibrosarcoma protuberans: recent clinical progress von McArthur, Grant

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Dysregulation of the basal RNA polymerase transcription apparatus in cancer von Bywater, Megan J., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma von Flaherty, Keith T, Puzanov, Igor, Kim, Kevin B, Ribas, Antoni, McArthur, Grant A, Sosman, Jeffrey A, O'Dwyer, Peter J, Lee, Richard J, Grippo, Joseph F, Nolop, Keith, Chapman, Paul B

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Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study von McArthur, G.A., Maio, M., Arance, A., Nathan, P., Blank, C., Avril, M.-F., Garbe, C., Hauschild, A., Schadendorf, D., Hamid, O., Fluck, M., Thebeau, M., Schachter, J., Kefford, R., Chamberlain, M., Makrutzki, M., Robson, S., Gonzalez, R., Margolin, K.

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Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study von Long, Georgina V, Atkinson, Victoria, Lo, Serigne, Sandhu, Shahneen, Guminski, Alexander D, Brown, Michael P, Wilmott, James S, Edwards, Jarem, Gonzalez, Maria, Scolyer, Richard A, Menzies, Alexander M, McArthur, Grant A

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A Microenvironment-Induced Myeloproliferative Syndrome Caused by Retinoic Acid Receptor γ Deficiency von Walkley, Carl R., Olsen, Gemma Haines, Dworkin, Sebastian, Fabb, Stewart A., Swann, Jeremy, McArthur, Grant A., Westmoreland, Susan V., Chambon, Pierre, Scadden, David T., Purton, Louise E.

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Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma von RIBAS, Antoni, KEFFORD, Richard, LORIGAN, Paul, KENDRA, Kari L, MAIO, Michele, TREFZER, Uwe, SMYLIE, Michael, MCARTHUR, Grant A, DRENO, Brigitte, NATHAN, Paul D, MACKIEWICZ, Jacek, KIRKWOOD, John M, MARSHALL, Margaret A, GOMEZ-NAVARRO, Jesus, BO HUANG, PAVLOV, Dmitri, HAUSCHILD, Axel, PUNT, Cornelis J. A, HAANEN, John B, MARMOL, Maribel, GARBE, Claus, GOGAS, Helen, SCHACHTER, Jacob, LINETTE, Gerald

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A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells von Solomon, Benjamin J, Desai, Jayesh, Rosenthal, Mark, McArthur, Grant A, Pattison, Scott T, Pattison, Stacey L, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Scott, Andrew M

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Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial von Ascierto, Paolo A, McArthur, Grant A, Dréno, Brigitte, Atkinson, Victoria, Liszkay, Gabrielle, Di Giacomo, Anna Maria, Mandalà, Mario, Demidov, Lev, Stroyakovskiy, Daniil, Thomas, Luc, de la Cruz-Merino, Luis, Dutriaux, Caroline, Garbe, Claus, Yan, Yibing, Wongchenko, Matthew, Chang, Ilsung, Hsu, Jessie J, Koralek, Daniel O, Rooney, Isabelle, Ribas, Antoni, Larkin, James

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