Patient-reported outcomes in high-risk HR+ /HER2- early breast cancer patients treated with endocrine therapy with or without palbociclib within the randomized PENELOPEB study von García-Sáenz, José Angel, Marmé, Frederik, Untch, Michael, Bonnefoi, Hervé, Kim, Sung-Bae, Bear, Harry, Mc Carthy, Nicole, Gelmon, Karen, Martin, Miguel, Kelly, Catherine M., Reimer, Toralf, Toi, Masakazu, Law, Ernest, Bhattacharyya, Helen, Gnant, Michael, Makris, Andreas, Seiler, Sabine, Burchardi, Nicole, Nekljudova, Valentina, Loibl, Sibylle, Rugo, Hope S.

Volltext

Detection of circulating tumor DNA following neoadjuvant chemotherapy and surgery to anticipate early relapse in ER positive and HER2 negative breast cancer: Analysis from the PENE... von Turner, Nicholas C., Marmé, Frederik, Kim, Sung-Bae, Bonnefoi, Herve R., García-Sáenz, José A., Torres, Antonio A., Bear, Harry Douglas, Tesch, Hans, Melé Olivé, Mireia, Mc Carthy, Nicole, Cruz Jurado, Josefina, Im, Seock-Ah, Liu, Yuan, Zhang, Zhe, Weber, Karsten Ernst, Felder, Bärbel, Nekljudova, Valentina, Reimer, Toralf, Denkert, Carsten, Loibl, Sibylle

Volltext

Abstract GS1-02: Phase III study of palbociclib combined with endocrine therapy (ET) in patients with hormone-receptor-positive (HR+), HER2-negative primary breast cancerand with h... von Loibl, Sibylle, Marmé, Frederik, Martin, Miguel, Untch, Michael, Bonnefoi, Hervé, Kim, Sung-Bae, Bear, Harry, Carthy, Nicole Mc, Olivé, Mireia Melé, Gelmon, Karen, Sáenz, José García, Kelly, Catherine M, Reimer, Toralf, Toi, Masakazu, Rugo, Hope S, Seiler, Sabine, Nekljudova, Valentina, Denkert, Carsten, Gnant, Michael, Makris, Andreas, Burchardi, Nicole, von Minckwitz, Gunter

Volltext

Palbociclib combined with endocrine treatment in breast cancer patients with high relapse risk after neoadjuvant chemotherapy: Subgroup analyses of premenopausal patients in PENELO... von Marmé, Frederik, Martin, Miguel, Untch, Michael, Bonnefoi, Herve R., Kim, Sung-Bae, Bear, Harry Douglas, Mc Carthy, Nicole, Gelmon, Karen A., García-Sáenz, José A., Kelly, Catherine Margaret, Reimer, Toralf, Toi, Masakazu, Rugo, Hope S., Gnant, Michael, Makris, Andreas, Lechuga, Mariajose, Seiler, Sabine, Seither, Fenja, Loibl, Sibylle

Volltext

Subgroup of post-neoadjuvant luminal-B tumors assessed by HTG in PENELOPE-B investigating palbociclib in high risk HER2-/HR+ breast cancer with residual disease von Denkert, Carsten, Marmé, Frederik, Martin, Miguel, Untch, Michael, Bonnefoi, Herve R., Witkiewicz, Agnieszka Katarzyna, Im, Seock-Ah, DeMichele, Angela, van 't Veer, Laura, Mc Carthy, Nicole, Gelmon, Karen A., Turner, Nicholas C., Rojo, Federico, Fasching, Peter A., Teply-Szymanski, Julia, Liu, Yuan, Toi, Masakazu, Gnant, Michael, Weber, Karsten Ernst, Loibl, Sibylle

Volltext

Patient-reported outcomes in high-risk HR+ /HER2- early breast cancer patients treated with endocrine therapy with or without palbociclib within the randomized PENELOPE B study von García-Sáenz, José Angel, Marmé, Frederik, Untch, Michael, Bonnefoi, Hervé, Kim, Sung-Bae, Bear, Harry, Mc Carthy, Nicole, Gelmon, Karen, Martin, Miguel, Kelly, Catherine M, Reimer, Toralf, Toi, Masakazu, Law, Ernest, Bhattacharyya, Helen, Gnant, Michael, Makris, Andreas, Seiler, Sabine, Burchardi, Nicole, Nekljudova, Valentina, Loibl, Sibylle, Rugo, Hope S

Volltext

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo von Ikram, M Kamran, Sim, Xueling, Xueling, Sim, Jensen, Richard A, Cotch, Mary Frances, Hewitt, Alex W, Ikram, M Arfan, Wang, Jie Jin, Klein, Ronald, Klein, Barbara E K, Breteler, Monique M B, Cheung, Ning, Liew, Gerald, Mitchell, Paul, Uitterlinden, Andre G, Rivadeneira, Fernando, Hofman, Albert, de Jong, Paulus T V M, van Duijn, Cornelia M, Kao, Linda, Cheng, Ching-Yu, Smith, Albert Vernon, Glazer, Nicole L, Lumley, Thomas, McKnight, Barbara, Psaty, Bruce M, Jonasson, Fridbert, Eiriksdottir, Gudny, Aspelund, Thor, Harris, Tamara B, Launer, Lenore J, Taylor, Kent D, Li, Xiaohui, Iyengar, Sudha K, Xi, Quansheng, Sivakumaran, Theru A, Mackey, David A, Macgregor, Stuart, Martin, Nicholas G, Young, Terri L, Bis, Josh C, Wiggins, Kerri L, Heckbert, Susan R, Hammond, Christopher J, Andrew, Toby, Fahy, Samantha, Attia, John, Holliday, Elizabeth G, Scott, Rodney J, Islam, F M Amirul, Rotter, Jerome I, McAuley, Annie K, Boerwinkle, Eric, Tai, E Shyong, Gudnason, Vilmundur, Siscovick, David S, Vingerling, Johannes R, Wong, Tien Y

Volltext

Genetic effects on gene expression across human tissues von Battle, Alexis, Brown, Christopher D, Engelhardt, Barbara E, Montgomery, Stephen B

Volltext

Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes von Zhou, Xueya, Feliciano, Pamela, Shu, Chang, Wang, Tianyun, Astrovskaya, Irina, Hall, Jacob B., Obiajulu, Joseph U., Wright, Jessica R., Murali, Shwetha C., Xu, Simon Xuming, Brueggeman, Leo, Thomas, Taylor R., Marchenko, Olena, Fleisch, Christopher, Barns, Sarah D., Snyder, LeeAnne Green, Han, Bing, Chang, Timothy S., Turner, Tychele N., Harvey, William T., Nishida, Andrew, O’Roak, Brian J., Geschwind, Daniel H., Michaelson, Jacob J., Volfovsky, Natalia, Eichler, Evan E., Shen, Yufeng, Chung, Wendy K.

Volltext

Analysis of protein-coding genetic variation in 60,706 humans von Lek, Monkol, Karczewski, Konrad J., Minikel, Eric V., Samocha, Kaitlin E., Banks, Eric, Fennell, Timothy, O’Donnell-Luria, Anne H., Ware, James S., Hill, Andrew J., Cummings, Beryl B., Tukiainen, Taru, Birnbaum, Daniel P., Kosmicki, Jack A., Duncan, Laramie E., Estrada, Karol, Zhao, Fengmei, Zou, James, Pierce-Hoffman, Emma, Berghout, Joanne, Cooper, David N., Deflaux, Nicole, DePristo, Mark, Do, Ron, Flannick, Jason, Fromer, Menachem, Gauthier, Laura, Goldstein, Jackie, Gupta, Namrata, Howrigan, Daniel, Kiezun, Adam, Kurki, Mitja I., Moonshine, Ami Levy, Natarajan, Pradeep, Orozco, Lorena, Peloso, Gina M., Poplin, Ryan, Rivas, Manuel A., Ruano-Rubio, Valentin, Rose, Samuel A., Ruderfer, Douglas M., Shakir, Khalid, Stenson, Peter D., Stevens, Christine, Thomas, Brett P., Tiao, Grace, Tusie-Luna, Maria T., Weisburd, Ben, Won, Hong-Hee, Yu, Dongmei, Altshuler, David M., Ardissino, Diego, Boehnke, Michael, Danesh, John, Donnelly, Stacey, Elosua, Roberto, Florez, Jose C., Gabriel, Stacey B., Getz, Gad, Glatt, Stephen J., Hultman, Christina M., Kathiresan, Sekar, Laakso, Markku, McCarroll, Steven, McCarthy, Mark I., McGovern, Dermot, McPherson, Ruth, Neale, Benjamin M., Palotie, Aarno, Purcell, Shaun M., Saleheen, Danish, Scharf, Jeremiah M., Sklar, Pamela, Sullivan, Patrick F., Tuomilehto, Jaakko, Tsuang, Ming T., Watkins, Hugh C., Wilson, James G., Daly, Mark J., MacArthur, Daniel G.

Volltext

Randomized Trial of Closed-Loop Control in Very Young Children with Type 1 Diabetes von Ware, Julia, Allen, Janet M, Boughton, Charlotte K, Wilinska, Malgorzata E, Hartnell, Sara, Thankamony, Ajay, de Beaufort, Carine, Schierloh, Ulrike, Fröhlich-Reiterer, Elke, Mader, Julia K, Kapellen, Thomas M, Rami-Merhar, Birgit, Tauschmann, Martin, Nagl, Katrin, Hofer, Sabine E, Campbell, Fiona M, Yong, James, Hood, Korey K, Lawton, Julia, Roze, Stephane, Sibayan, Judy, Bocchino, Laura E, Kollman, Craig, Hovorka, Roman

Volltext

Landscape of X chromosome inactivation across human tissues von Tukiainen, Taru, Villani, Alexandra-Chloé, Yen, Angela, Rivas, Manuel A., Marshall, Jamie L., Satija, Rahul, Aguirre, Matt, Gauthier, Laura, Fleharty, Mark, Kirby, Andrew, Cummings, Beryl B., Castel, Stephane E., Karczewski, Konrad J., Aguet, François, Byrnes, Andrea, Lappalainen, Tuuli, Regev, Aviv, Ardlie, Kristin G., Hacohen, Nir, MacArthur, Daniel G.

Volltext

Dynamic landscape and regulation of RNA editing in mammals von Tan, Meng How, Li, Qin, Shanmugam, Raghuvaran, Piskol, Robert, Kohler, Jennefer, Young, Amy N., Liu, Kaiwen Ivy, Zhang, Rui, Ramaswami, Gokul, Ariyoshi, Kentaro, Gupte, Ankita, Keegan, Liam P., George, Cyril X., Ramu, Avinash, Huang, Ni, Pollina, Elizabeth A., Leeman, Dena S., Rustighi, Alessandra, Goh, Y. P. Sharon, Chawla, Ajay, Del Sal, Giannino, Peltz, Gary, Brunet, Anne, Conrad, Donald F., Samuel, Charles E., O’Connell, Mary A., Walkley, Carl R., Nishikura, Kazuko, Li, Jin Billy

Volltext

The UK10K project identifies rare variants in health and disease von Walter, Klaudia, Min, Josine L, Huang, Jie, Crooks, Lucy, Memari, Yasin, McCarthy, Shane, Perry, John R B, Xu, ChangJiang, Futema, Marta, Lawson, Daniel, Iotchkova, Valentina, Schiffels, Stephan, Hendricks, Audrey E, Danecek, Petr, Li, Rui, Floyd, James, Wain, Louise V, Barroso, Inês, Humphries, Steve E, Hurles, Matthew E, Zeggini, Eleftheria, Barrett, Jeffrey C, Plagnol, Vincent, Richards, J Brent, Greenwood, Celia M T, Timpson, Nicholas J, Durbin, Richard, Soranzo, Nicole

Volltext

The Genotype-Tissue Expression (GTEx) project von Lonsdale, John, Thomas, Jeffrey, Salvatore, Mike, Phillips, Rebecca, Hasz, Richard, Walters, Gary, Garcia, Fernando, Young, Nancy, Karasik, Ellen, Gillard, Bryan, Ramsey, Kimberley, Magazine, Harold, Syron, John, Fleming, Johnelle, Traino, Heather, Mosavel, Maghboeba, Barker, Laura, Rohrer, Dan, Maxim, Dan, Filkins, Dana, Harbach, Philip, Cortadillo, Eddie, Berghuis, Bree, Turner, Lisa, Hudson, Eric, Robb, James, Branton, Phillip, Korzeniewski, Greg, Shive, Charles, Tabor, David, Groch, Kevin, Nampally, Sreenath, Buia, Steve, Zimmerman, Angela, Smith, Anna, Burges, Robin, Robinson, Karna, Valentino, Kim, Bradbury, Deborah, Diaz-Mayoral, Norma, Kennedy, Mary, Erickson, Kenyon, Ardlie, Kristin, Winckler, Wendy, Getz, Gad, MacArthur, Daniel, Kellis, Manolis, Thomson, Alexander, Gelfand, Ellen, Donovan, Molly, Meng, Yan, Marcus, Yvonne, Basile, Margaret, Zhu, Jun, Tu, Zhidong, Cox, Nancy J, Gamazon, Eric R, Im, Hae Kyung, Konkashbaev, Anuar, Pritchard, Jonathan, Flutre, Timothèe, Wen, Xiaoquan, Dermitzakis, Emmanouil T, Guigo, Roderic, Monlong, Jean, Sammeth, Michael, Koller, Daphne, Battle, Alexis, Mostafavi, Sara, McCarthy, Mark, Rivas, Manual, Rusyn, Ivan, Nobel, Andrew, Wright, Fred, Shabalin, Andrey, Sturcke, Anne, Paschal, Justin, Anderson, James M, Wilder, Elizabeth L, Derr, Leslie K, Green, Eric D, Temple, Gary, Volpi, Simona, Boyer, Joy T, Thomson, Elizabeth J, Guyer, Mark S, Ng, Cathy, Abdallah, Assya, Colantuoni, Deborah, Insel, Thomas R, Koester, Susan E, Little, A Roger, Bender, Patrick K, Lehner, Thomas, Compton, Carolyn C, Vaught, Jimmie B, Sawyer, Sherilyn, Lockhart, Nicole C, Demchok, Joanne, Moore, Helen F

Volltext

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project von Carithers, Latarsha J, Ardlie, Kristin, Barcus, Mary, Branton, Philip A, Britton, Angela, Buia, Stephen A, Compton, Carolyn C, DeLuca, David S, Peter-Demchok, Joanne, Gelfand, Ellen T, Guan, Ping, Korzeniewski, Greg E, Lockhart, Nicole C, Rabiner, Chana A, Rao, Abhi K, Robinson, Karna L, Roche, Nancy V, Sawyer, Sherilyn J, Segrè, Ayellet V, Shive, Charles E, Smith, Anna M, Sobin, Leslie H, Undale, Anita H, Valentino, Kimberly M, Vaught, Jim, Young, Taylor R, Moore, Helen M

Volltext

Timing, rates and spectra of human germline mutation von Rahbari, Raheleh, Wuster, Arthur, Lindsay, Sarah J, Hardwick, Robert J, Alexandrov, Ludmil B, Al Turki, Saeed, Dominiczak, Anna, Morris, Andrew, Porteous, David, Smith, Blair, Stratton, Michael R, Hurles, Matthew E

Volltext

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements von Grundberg, Elin, Meduri, Eshwar, Sandling, Johanna K., Hedman, Åsa K., Keildson, Sarah, Buil, Alfonso, Busche, Stephan, Yuan, Wei, Nisbet, James, Sekowska, Magdalena, Wilk, Alicja, Barrett, Amy, Small, Kerrin S., Ge, Bing, Caron, Maxime, Shin, So-Youn, Ahmadi, Kourosh R., Ainali, Chrysanthi, Barrett, Amy, Bataille, Veronique, Bell, Jordana T., Buil, Alfonso, Deloukas, Panos, Dermitzakis, Emmanouil T., Dimas, Antigone S., Durbin, Richard, Glass, Daniel, Grundberg, Elin, Hassanali, Neelam, Hedman, Åsa K., Ingle, Catherine, Knowles, David, Krestyaninova, Maria, Lindgren, Cecilia M., Lowe, Christopher E., McCarthy, Mark I., Meduri, Eshwar, di Meglio, Paola, Min, Josine L., Montgomery, Stephen B., Nestle, Frank O., Nica, Alexandra C., Nisbet, James, O’Rahilly, Stephen, Parts, Leopold, Potter, Simon, Sandling, Johanna, Sekowska, Magdalena, Shin, So-Youn, Small, Kerrin S., Soranzo, Nicole, Spector, Tim D., Surdulescu, Gabriela, Travers, Mary E., Tsaprouni, Loukia, Tsoka, Sophia, Wilk, Alicja, Yang, Tsun-Po, Zondervan, Krina T., Lathrop, Mark, Dermitzakis, Emmanouil T., McCarthy, Mark I., Spector, Timothy D., Bell, Jordana T., Deloukas, Panos

Volltext

A Demonstration of the Collaborative Replication and Education Project: Replication Attempts of the Red-Romance Effect von Wagge, Jordan R, Baciu, Cristina, Banas, Kasia, Nadler, Joel T, Schwarz, Sascha, Weisberg, Yanna, IJzerman, Hans

Volltext

Sequence variants at CHRNB3 - CHRNA6 and CYP2A6 affect smoking behavior von Perola, Markus, McCarthy, Mark I, Keskitalo, Kaisu, Pergadia, Michele L, Salomaa, Veikko, Stefansson, Hreinn, Kovacs, Peter, Aben, Katja K, Peltonen, Leena, Giegling, Ina, Lezcano, Victoria, Mueller, Thomas, Thorsteinsdottir, Unnur, Geller, Frank, Hartikainen, Anna-Liisa, Rujescu, Dan, Franklin, Wilbur A, Ashraf, Haseem, Stefansson, Kari, Walter, Stefan, van Duijn, Cornelia M, Mayordomo, Jose I, Willemsen, Gonneke, Kiemeney, Lambertus A, Pedersen, Jesper Holst, Huei-Yi, Shen, Tyrfingsson, Thorarinn, Stumvoll, Michael, Jones, Gregory T, Uitterlinden, André G, Allen, Maxine, Dieplinger, Benjamin, Krestyaninova, Maria, Amin, Najaf, van Rij, Andre M, Gulcher, Jeffrey R, Valdes, Ana M, Mangino, Massimo, Heath, Andrew C, Döring, Angela, Gieger, Christian, Gudjonsdottir, Iris H, Hofman, Albert, Jonsson, Steinn, Kaprio, Jaakko, Mägi, Reedik, Dirksen, Asger, Nelis, Mari, Thompson, John R, Hottenga, Jouke Jan, Garcia-Prats, Maria D, Metspalu, Andres, Hall, Alistair S, Oostra, Ben A, Matthiasson, Stefan E, Prokopenko, Inga, Dahmen, Norbert, Madden, Pamela A F, Wolf, Holly, Steves, Claire, Nitz, Barbara, Kettunen, Johannes, Martin, Nicholas G, Spector, Tim D, Thorgeirsson, Thorgeir E, Haltmayer, Meinhard, Ripatti, Samuli, Gudbjartsson, Daniel F, Esko, Tõnu, Rafnar, Thorunn, Soranzo, Nicole, Vink, Jacqueline M, De Diego, Veronica, Laitinen, Jaana, Järvelin, Marjo-Riitta, Wichmann, H-Erich, Pouta, Anneli, Penninx, Brenda W, Boomsma, Dorret I, Surakka, Ida, Rawal, Rajesh, Aulchenko, Yurii S, Sulem, Patrick, Gretarsdottir, Solveig, Oskarsson, Hogni, Isohanni, Matti, Tönjes, Anke, Saez, Berta, Lindholt, Jes S, Tiemeier, Henning, Samani, Nilesh J, den Heijer, Martin, Vogelzangs, Nicole, Montgomery, Grant W

Volltext