In vitro generation of human pluripotent stem cell derived lung organoids von Dye, Briana R, Hill, David R, Ferguson, Michael A H, Tsai, Yu-Hwai, Nagy, Melinda S, Dyal, Rachel, Wells, James M, Mayhew, Christopher N, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R

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An in vivo model of human small intestine using pluripotent stem cells von Watson, Carey L, Mahe, Maxime M, Múnera, Jorge, Howell, Jonathan C, Sundaram, Nambirajan, Poling, Holly M, Schweitzer, Jamie I, Vallance, Jefferson E, Mayhew, Christopher N, Sun, Ying, Grabowski, Gregory, Finkbeiner, Stacy R, Spence, Jason R, Shroyer, Noah F, Wells, James M, Helmrath, Michael A

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A review of protocols for brain organoids and applications for disease modeling von Mayhew, Christopher N., Singhania, Richa

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Properties of neurons derived from induced pluripotent stem cells of Gaucher disease type 2 patient fibroblasts: potential role in neuropathology von Sun, Ying, Florer, Jane, Mayhew, Christopher N, Jia, Zhanfeng, Zhao, Zhiying, Xu, Kui, Ran, Huimin, Liou, Benjamin, Zhang, Wujuan, Setchell, Kenneth D R, Gu, Jianguo, Grabowski, Gregory A

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Proliferative Suppression by CDK4/6 Inhibition: Complex Function of the Retinoblastoma Pathway in Liver Tissue and Hepatoma Cells von Rivadeneira, Dayana B, Mayhew, Christopher N, Thangavel, Chellappagounder, Sotillo, Elena, Reed, Christopher A, Graña, Xavier, Knudsen, Erik S

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iPSC-derived neural precursor cells engineering GBA1 recovers acid β-glucosidase deficiency and diminishes α-synuclein and neuropathology von Peng, Yanyan, Liou, Benjamin, Lin, Yi, Mayhew, Christopher N., Fleming, Sheila M., Sun, Ying

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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids von Ouchi, Rie, Togo, Shodai, Kimura, Masaki, Shinozawa, Tadahiro, Koido, Masaru, Koike, Hiroyuki, Thompson, Wendy, Karns, Rebekah A., Mayhew, Christopher N., McGrath, Patrick S., McCauley, Heather A., Zhang, Ran-Ran, Lewis, Kyle, Hakozaki, Shoyo, Ferguson, Autumn, Saiki, Norikazu, Yoneyama, Yosuke, Takeuchi, Ichiro, Mabuchi, Yo, Akazawa, Chihiro, Yoshikawa, Hiroshi Y., Wells, James M., Takebe, Takanori

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Activated STAT5 Confers Resistance to Intestinal Injury by Increasing Intestinal Stem Cell Proliferation and Regeneration von Gilbert, Shila, Nivarthi, Harini, Mayhew, Christopher N., Lo, Yuan-Hung, Noah, Taeko K., Vallance, Jefferson, Rülicke, Thomas, Müller, Mathias, Jegga, Anil G., Tang, Wenjuan, Zhang, Dongsheng, Helmrath, Michael, Shroyer, Noah, Moriggl, Richard, Han, Xiaonan

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Modelling human development and disease in pluripotent stem-cell-derived gastric organoids von McCracken, Kyle W., Catá, Emily M., Crawford, Calyn M., Sinagoga, Katie L., Schumacher, Michael, Rockich, Briana E., Tsai, Yu-Hwai, Mayhew, Christopher N., Spence, Jason R., Zavros, Yana, Wells, James M.

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Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells von Matsui, Satoshi, Shiley, Joseph R., Buckley, Morgan, Lim, Hee-Woong, Hu, Yueh-Chiang, Mayhew, Christopher N., Iwafuchi, Makiko

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High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids von Xia, Sunny, Bozóky, Zoltán, Di Paola, Michelle, Laselva, Onofrio, Ahmadi, Saumel, Jiang, Jia Xin, Pitstick, Amy L, Jiang, Chong, Rotin, Daniela, Mayhew, Christopher N, Jones, Nicola L, Bear, Christine E

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Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage von Chlon, Timothy M., Ruiz-Torres, Sonya, Maag, Logan, Mayhew, Christopher N., Wikenheiser-Brokamp, Kathryn A., Davies, Stella M., Mehta, Parinda, Myers, Kasiani C., Wells, James M., Wells, Susanne I.

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Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells von Ji, Hong, PhD, Zhang, Xue, PhD, Oh, Sunghee, PhD, Mayhew, Christopher N., PhD, Ulm, Ashley, BA, Somineni, Hari K., MS, Ericksen, Mark, BS, Wells, James M., PhD, Khurana Hershey, Gurjit K., MD, PhD

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Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro von Spence, Jason R., Mayhew, Christopher N., Rankin, Scott A., Kuhar, Matthew F., Vallance, Jefferson E., Tolle, Kathryn, Hoskins, Elizabeth E., Kalinichenko, Vladimir V., Wells, Susanne I., Zorn, Aaron M., Shroyer, Noah F., Wells, James M.

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Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency von Li, Chao Zheng, Ogawa, Hiromi, Ng, Soon Seng, Chen, Xindi, Kishimoto, Eriko, Sakabe, Kokoro, Fukami, Aiko, Hu, Yueh-Chiang, Mayhew, Christopher N., Hellmann, Jennifer, Miethke, Alexander, Tasnova, Nahrin L., Blackford, Samuel J.I., Tang, Zu Ming, Syanda, Adam M., Ma, Liang, Xiao, Fang, Sambrotta, Melissa, Tavabie, Oliver, Soares, Filipa, Baker, Oliver, Danovi, Davide, Hayashi, Hisamitsu, Thompson, Richard J., Rashid, S. Tamir, Asai, Akihiro

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Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate von Matsui, Satoshi, Granitto, Marissa, Buckley, Morgan, Ludwig, Katie, Koigi, Sandra, Shiley, Joseph, Zacharias, William J., Mayhew, Christopher N., Lim, Hee-Woong, Iwafuchi, Makiko

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Digitalized Human Organoid for Wireless Phenotyping von Kimura, Masaki, Azuma, Momoko, Zhang, Ran-Ran, Thompson, Wendy, Mayhew, Christopher N., Takebe, Takanori

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E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis von Powers, John T, Hong, SungKi, Mayhew, Christopher N, Rogers, Pamela M, Knudsen, Erik S, Johnson, David G

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Intravenous infusion of iPSC-derived neural precursor cells increases acid β-glucosidase function in the brain and lessens the neuronopathic phenotype in a mouse model of Gaucher d... von Peng, Yanyan, Liou, Benjamin, Inskeep, Venette, Blackwood, Rachel, Mayhew, Christopher N, Grabowski, Gregory A, Sun, Ying

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RB Loss Promotes Aberrant Ploidy by Deregulating Levels and Activity of DNA Replication Factors von Srinivasan, Seetha V., Mayhew, Christopher N., Schwemberger, Sandy, Zagorski, William, Knudsen, Erik S.

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