The Minimally Clinically Important Difference (MCID): What Difference Does It Make? von Bernstein, Jonathan A., MD, Mauger, Dave T., PhD

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Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma von Huang, Brendan K, Elicker, Brett M, Henry, Travis S, Kallianos, Kimberly G, Hahn, Lewis D, Tang, Monica, Heng, Franklin, McCulloch, Charles E, Bhakta, Nirav R, Majumdar, Sharmila, Choi, Jiwoong, Denlinger, Loren C, Fain, Sean B, Hastie, Annette T, Hoffman, Eric A, Israel, Elliot, Jarjour, Nizar N, Levy, Bruce D, Mauger, Dave T, Sumino, Kaharu, Wenzel, Sally E, Castro, Mario, Woodruff, Prescott G, Fahy, John V, Sarp, For The Nhlbi Severe Asthma Research Program

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Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone von Guilbert, Theresa W., MD, Mauger, David T., PhD, Allen, David B., MD, Zeiger, Robert S., MD, PhD, Lemanske, Robert F., MD, Szefler, Stanley J., MD, PhD, Strunk, Robert C., MD, Bacharier, Leonard B., MD, Covar, Ronina, MD, Sorkness, Christine A., PharmD, Taussig, Lynn M., MD, Martinez, Fernando D., MD

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The Human Gut Microbiomial Metabolite Enterolactone Associates With Better Asthma Control von Cardet, Juan Carlos, Wang, Zeneng, Casale, Thomas, Comhair, Suzy, Hazen, Stanley, Lampe, Johanna, Mauger, Dave, Phillips, Brenda, Israel, Elliot

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Assessment of genetic factor and depression interactions for asthma symptom severity in cohorts of childhood and elderly asthmatics von Park, Heung-Woo, Song, Woo-Jung, Cho, Sang-Heon, McGeachie, Michael J., Martinez, Fernando, Mauger, Dave, Bender, Bruce G., Tantisira, Kelan G.

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Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children von Guilbert, Theresa W., Beigelman, Avraham, Fitzpatrick, Anne M., Cabana, Michael D., Castro, Mario, Chmiel, James F., Daines, Michael, Gaffin, Jonathan M., Gentile, Deborah A., Kelly, H. William, Lazarus, Stephen C., Morgan, Wayne, Moy, James, Peters, Stephen P., Pongracic, Jacqueline A., Raissy, Hengameh H., Ross, Kristie, Sorkness, Christine, Teague, W. Gerald, Thyne, Shannon, Bartnikas, Lisa, Bouzaher, Alisha, Burke, Christopher, Cavanaugh, Matthew, Chen, Julia, Cunningham, Elizabeth, Cunningham, Amparito, Friedlander, James, Kantor, David, Permaul, Perdita, Rossi, Melinda, Schierembergg, Doris, Troung, Jennifer, Zhou, Joseph, Chmielewski, Jill, Fishbein, Anna, Kumar, Rajesh, Qamar, Nashmia, Riordan, Mary, Szychlinski, Christine, Tsang, Daniel, Munoz-Mendoza, Diana, Thompson, Benjamin, Malka, Jonathan, Phillips, Melanie, Sundstrom, D., Davies, Lea, Kelly, Franceska, Morales, Esmeralda, Redway, Abby, Spicher, Mary, Knutson, Megan R., Miller, Kelly, Promer, Jennifer, Dubin, Patricia, Holt, Lori, Kufen, Adam, Parente, Julianne, Smith, Catherine, Spahr, Jonathan, Weiner, Daniel J., Kerns, Leigh A., Logan, Laurie, Misplay, Sara, Skoner, David, Smith, Glennys, Caldwell, Wanda, Dula, Courtney, Ellis, Alysa, Horner, Caroline, Norris, Tina, Rivera-Spoljaric, Katherine, Rodriguez, Oscar, Bowman, Jessica, Bowyer, Vicky, Hawkey, Sara, McKean, Michelle, Tom, Katherine, Harrison, Keonna, Long, Dayna, Marbin, Jyothi, Mok, Robert, Stessel, Hollie, Green, Deb, Wolf, Donna, Beaty, Timothy, DeMuth, Karen, Dodds, Jennifer, Simon, Dawn M., Whitlock, Denise, Brown, Shanae, Boehmer, Susan, Bowman, Matthew, Ferrari, Linda, Gern, Beth, Merchlinski, Aimee, Tekely, Daniel, Texter, Lindsay, Updegrave, Angela, Zimmerman, Ronald

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Genome-wide Association Identifies the T Gene as a Novel Asthma Pharmacogenetic Locus von TANTISIRA, Kelan G, DAMASK, Amy, BOUSHEY, Homer A, CHINCHILLI, Vernon M, MAUGER, Dave, WEISS, Scott T, ISRAEL, Elliot, SZEFLER, Stanley J, SCHUEMANN, Brooke, MARKEZICH, Amy, SU, Jessica, KLANDERMAN, Barbara, SYLVIA, Jody, RONGLING WU, MARTINEZ, Fernando

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Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design von Oelsner, Elizabeth C, Krishnaswamy, Akshaya, Balte, Pallavi P, Allen, Norrina Bai, Ali, Tauqeer, Anugu, Pramod, Andrews, Howard F, Arora, Komal, Asaro, Alyssa, Barr, R Graham, Bertoni, Alain G, Bon, Jessica, Boyle, Rebekah, Chang, Arunee A, Chen, Grace, Coady, Sean, Cole, Shelley A, Coresh, Josef, Cornell, Elaine, Correa, Adolfo, Couper, David, Cushman, Mary, Demmer, Ryan T, Elkind, Mitchell S V, Folsom, Aaron R, Fretts, Amanda M, Gabriel, Kelley P, Gallo, Linda C, Gutierrez, Jose, Han, Mei Lan K, Henderson, Joel M, Howard, Virginia J, Isasi, Carmen R, Jacobs Jr, David R, Judd, Suzanne E, Mukaz, Debora Kamin, Kanaya, Alka M, Kandula, Namratha R, Kaplan, Robert C, Kinney, Gregory L, Kucharska-Newton, Anna, Lee, Joyce S, Lewis, Cora E, Levine, Deborah A, Levitan, Emily B, Levy, Bruce D, Make, Barry J, Malloy, Kimberly, Manly, Jennifer J, Mendoza-Puccini, Carolina, Meyer, Katie A, Min, Yuan-I Nancy, Moll, Matthew R, Moore, Wendy C, Mauger, David, Ortega, Victor E, Palta, Priya, Parker, Monica M, Phipatanakul, Wanda, Post, Wendy S, Postow, Lisa, Psaty, Bruce M, Regan, Elizabeth A, Ring, Kimberly, Roger, Véronique L, Rotter, Jerome I, Rundek, Tatjana, Sacco, Ralph L, Schembri, Michael, Schwartz, David A, Seshadri, Sudha, Shikany, James M, Sims, Mario, Hinckley Stukovsky, Karen D, Talavera, Gregory A, Tracy, Russell P, Umans, Jason G, Vasan, Ramachandran S, Watson, Karol E, Wenzel, Sally E, Winters, Karen, Woodruff, Prescott G, Xanthakis, Vanessa, Zhang, Ying, Zhang, Yiyi

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Genome-wide association study of the age of onset of childhood asthma von Forno, Erick, MD, MPH, Lasky-Su, Jessica, ScD, Himes, Blanca, PhD, Howrylak, Judie, MD, Ramsey, Clare, MD, MPH, Brehm, John, MD, MPH, Klanderman, Barbara, PhD, Ziniti, John, BA, Melén, Erik, MD, PhD, Pershagen, Goran, MD, PhD, Wickman, Magnus, MD, PhD, Martinez, Fernando, MD, Mauger, Dave, PhD, Sorkness, Christine, PharmD, Tantisira, Kelan, MD, Raby, Benjamin A., MD, MPH, Weiss, Scott T., MD, MS, Celedón, Juan C., MD, DrPH

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Genome-wide association study of short-acting β2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3 von Israel, Elliot, Lasky-Su, Jessica, Markezich, Amy, Damask, Amy, Szefler, Stanley J, Schuemann, Brooke, Klanderman, Barbara, Sylvia, Jody, Kazani, Shamsah, Wu, Rongling, Martinez, Fernando, Boushey, Homer A, Chinchilli, Vernon M, Mauger, Dave, Weiss, Scott T, Tantisira, Kelan G

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Loss of bronchoprotection with ICS plus LABA treatment, β-receptor dynamics, and the effect of alendronate von Cardet, Juan Carlos, Jiang, Xiaofeng, Lu, Quan, Gerard, Norma, McIntire, Kristen, Boushey, Homer A., Castro, Mario, Chinchilli, Vernon M., Codispoti, Christopher D., Dyer, Anne-Marie, Holguin, Fernando, Kraft, Monica, Lazarus, Stephen, Lemanske, Robert F., Lugogo, Njira, Mauger, Dave, Moore, Wendy C., Moy, James, Ortega, Victor E., Peters, Stephen P., Smith, Lewis J., Solway, Julian, Sorkness, Christine A., Sumino, Kaharu, Wechsler, Michael E., Wenzel, Sally, Israel, Elliot

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Reply von Cardet, Juan Carlos, Jiang, Xiaofeng, Lu, Quan, Gerard, Norma, McIntire, Kristen, Boushey, Homer A., Castro, Mario, Chinchilli, Vernon M., Codispoti, Christopher D., Dyer, Anne-Marie, Holguin, Fernando, Kraft, Monica, Lazarus, Stephen, Lemanske, Robert F., Lugogo, Njira, Mauger, Dave, Moore, Wendy C., Moy, James, Ortega, Victor E., Peters, Stephen P., Smith, Lewis J., Solway, Julian, Sorkness, Christine A., Sumino, Kaharu, Wechsler, Michael E., Wenzel, Sally, Israel, Elliot

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Reply von Cardet, Juan Carlos, Jiang, Xiaofeng, Lu, Quan, Gerard, Norma, McIntire, Kristen, Boushey, Homer A, Castro, Mario, Chinchilli, Vernon M, Codispoti, Christopher D, Dyer, Anne-Marie, Holguin, Fernando, Kraft, Monica, Lazarus, Stephen, Lemanske, Robert F, Lugogo, Njira, Mauger, Dave, Moore, Wendy C, Moy, James, Ortega, Victor E, Peters, Stephen P, Smith, Lewis J, Solway, Julian, Sorkness, Christine A, Sumino, Kaharu, Wechsler, Michael E, Wenzel, Sally, Israel, Elliot

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Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents von Park, So-Young, Fowler, Stephen, Shaw, Dominic E, Adcock, Ian M, Sousa, Ana R, Djukanovic, Ratko, Dahlen, Sven-Erik, Sterk, Peter J, Kermani, Nazanin Zounemat, Calhoun, William, Israel, Elliot, Castro, Mario, Mauger, Dave, Meyers, Deborah, Bleecker, Eugene, Moore, Wendy, Busse, William, Jarjour, Nizar, Denlinger, Loren, Levy, Bruce, Choi, Byoung-Hwui, Kim, Sae-Hoon, Jang, An-Soo, Lee, Taehoon, Cho, Young-Joo, Shin, Yoo Seob, Cho, Sang-Heon, Won, Sungho, Cruz, Alvaro A, Wenzel, Sally E, Chung, Kian Fan, Kim, Tae-Bum

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Assessment of genetic factor and depression interactions for asthma symptom severity in cohorts of childhood and elderly asthmatics von Park, Heung-Woo, Song, Woo-Jung, Cho, Sang-Heon, McGeachie, Michael J., Martinez, Fernando, Mauger, Dave, Bender, Bruce G., Tantisira, Kelan G.

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Abstract B082: A novel, potent and selective ribonucleotide reductase (RNR) inhibitor, BBI-825, blocks extrachromosomal DNA (ecDNA) amplification-mediated resistance to KRASG12C in... von Chowdhry, Sudhir, Hansen, Ryan, Mauger, Jacques, Pferdekamper, AnneMarie, Tse, Edison, Norman, Ben, Moininazeri, Jafar, Garcia, Salvador, Truong, Yen, Liao, Debbie, Lange, Joshua, Holmes, Evan, Celeste, Anthony, Solis, Dave, Steffy, Auzon, Plum, Joshua, Wiese, Julie, Apuy, Julius, Ardeshiri, Ardalan, Milutinovic, Snezana, Wilkinson, Deepti, Pinkerton, Anthony, Hassig, Christian, Kasibhatla, Shailaja

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Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma von Ortega, Victor E, Daya, Michelle, Szefler, Stanley J, Bleecker, Eugene R, Chinchilli, Vernon M, Phipatanakul, Wanda, Mauger, Dave, Martinez, Fernando D, Herrera-Luis, Esther, Pino-Yanes, Maria, Hawkins, Gregory A, Ampleford, Elizabeth J, Kunselman, Susan J, Cox, Corey, Bacharier, Leonard B, Cabana, Michael D, Cardet, Juan Carlos, Castro, Mario, Denlinger, Loren C, Eng, Celeste, Fitzpatrick, Anne M, Holguin, Fernando, Hu, Donglei, Jackson, Daniel J, Jarjour, Nizar, Kraft, Monica, Krishnan, Jerry A, Lazarus, Stephen C, Lemanske, Robert F, Lima, John J, Lugogo, Njira, Mak, Angel, Moore, Wendy C, Naureckas, Edward T, Peters, Stephen P, Pongracic, Jacqueline A, Sajuthi, Satria P, Seibold, Max A, Smith, Lewis J, Solway, Julian, Sorkness, Christine A, Wenzel, Sally, White, Steven R, Burchard, Esteban G, Barnes, Kathleen, Meyers, Deborah A, Israel, Elliot, Wechsler, Michael E, Ali-Dinar, Tarig, Bartnikas, Lisa, Baxi, Sachin, Beigelman, Avraham, Benson, Mindy, Blake, Kathryn V., Burke-Roberts, Elizabeth, Cernadas, Manuela, Chmiel, James F., Covar, Ronina, DiMango, Emily, Gaffin, Jonathan, Gentile, Deborah, Grossman, Nicole, Hautpman, Marissa, Kantor, David, Kumar, Harsha, LaForce, Craig F., Lang, Jason, Long, Dayna, Louisias, Margee, Morgan, Wayne, Moy, James, Myers, Ross E., Olin, J. Tod, Permaul, Perdita, Que, Loretta, Raissy, Hengameh, Robison, Rachel G., Ross, Kristie, Sheehan, William, Sullivan-Vedder, Lisa, Wright, Lakeia

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Genome-Wide Association Study of Short-Acting β 2 -Agonists. A Novel Genome-Wide Significant Locus on Chromosome 2 near ASB3 von Israel, Elliot, Lasky-Su, Jessica, Markezich, Amy, Damask, Amy, Szefler, Stanley J., Schuemann, Brooke, Klanderman, Barbara, Sylvia, Jody, Kazani, Shamsah, Wu, Rongling, Martinez, Fernando, Boushey, Homer A., Chinchilli, Vernon M., Mauger, Dave, Weiss, Scott T., Tantisira, Kelan G.

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Genome-Wide Association Study of Short-Acting [Beta]^sub 2^-Agonists: A Novel Genome-Wide Significant Locus on Chromosome 2 near ASB3 von Israel, Elliot, Lasky-Su, Jessica, Markezich, Amy, Damask, Amy, Szefler, Stanley J, Schuemann, Brooke, Klanderman, Barbara, Sylvia, Jody, Kazani, Shamsah, Wu, Rongling, Martinez, Fernando, Boushey, Homer A, Chinchilli, Vernon M, Mauger, Dave, Weiss, Scott T, Tantisira, Kelan G

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Pharmacogenetic Studies of Long-Acting Beta Agonist and Inhaled Corticosteroid Response in Randomized Controlled Trials of African Descent Minorities with Asthma von Ortega, Victor E., Daya, Michelle, Szefler, Stanley J., Bleecker, Eugene R., Chinchilli, Vernon M., Phipatanakul, Wanda, Mauger, Dave, Martinez, Fernando D., Herrera-Luis, Esther, Pino-Yanes, Maria, Hawkins, Gregory A., Ampleford, Elizabeth J., Kunselman, Susan J., Cox, Corey, Bacharier, Leonard B., Cabana, Michael D., Cardet, Juan Carlos, Castro, Mario, Denlinger, Loren C., Eng, Celeste, Fitzpatrick, Anne M., Holguin, Fernando, Hu, Donglei, Jackson, Daniel J., Jarjour, Nizar, Kraft, Monica, Krishnan, Jerry A., Lazarus, Stephen C., Lemanske, Robert F., Lima, John J., Lugogo, Njira, Mak, Angel, Moore, Wendy C., Naureckas, Edward T., Peters, Stephen P., Pongracic, Jacqueline A., Sajuthi, Satria P., Seibold, Max A., Smith, Lewis J., Solway, Julian, Sorkness, Christine A., Wenzel, Sally, White, Steven R., Burchard, Esteban G., Barnes, Kathleen, Meyers, Deborah A., Israel, Elliot, Wechsler, Michael E.

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