Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC von Morrone, Seamus R., Matyszewski, Mariusz, Yu, Xiong, Delannoy, Michael, Egelman, Edward H., Sohn, Jungsan

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Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome von Matyszewski, Mariusz, Zheng, Weili, Lueck, Jacob, Mazanek, Zachary, Mohideen, Naveen, Lau, Albert Y., Egelman, Edward H., Sohn, Jungsan

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Digital signaling network drives the assembly of the AIM2-ASC inflammasome von Matyszewski, Mariusz, Morrone, Seamus R., Sohn, Jungsan

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Preparation of filamentous proteins for electron microscopy visualization and reconstruction von Matyszewski, Mariusz, Sohn, Jungsan

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Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules von Snead, David M., Matyszewski, Mariusz, Dickey, Andrea M., Lin, Yu Xuan, Leschziner, Andres E., Reck-Peterson, Samara L.

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Mechanism of Parkinson's Disease-Linked LRRK2's Interaction with Microtubules von Reck-Peterson, Samara L., Snead, David, Matyszewski, Mariusz, Dickey, Andrea M., Xuan Lin, Yu, Leschziner, Andres

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Mechanism of Parkinson’s disease-linked LRRK2 microtubule binding von Matyszewski, Mariusz, Snead, David M., Dickey, Andrea M., Lin, Yu X., Leschziner, Andres E., Reck-Peterson, Samara L.

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Characterization of AIM2 DNA-Binding Properties and Filament Formation von Morrone, Seamus, Matyszewski, Mariusz, Sohn, Jungsan

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Cryo-EM structure of the NLRC4CARD filament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly von Matyszewski, Mariusz, Zheng, Weili, Lueck, Jacob, Antiochos, Brendan, Egelman, Edward H., Sohn, Jungsan

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IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome von Antiochos, Brendan, Matyszewski, Mariusz, Sohn, Jungsan, Casciola-Rosen, Livia, Rosen, Antony

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Cryo-EM structure of the NLRC4 CARD filament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly von Matyszewski, Mariusz, Zheng, Weili, Lueck, Jacob, Antiochos, Brendan, Egelman, Edward H, Sohn, Jungsan

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Structural basis for Parkinson's Disease-linked LRRK2's binding to microtubules von Snead, David M., Matyszewski, Mariusz, Dickey, Andrea M., Lin, Yu Xuan, Leschziner, Andres E., Reck-Peterson, Samara L.

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Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase von Mazur, Marzena, Bartoszewicz, Agnieszka, Dymek, Barbara, Salamon, Magdalena, Andryianau, Gleb, Kowalski, Michał, Olejniczak, Sylwia, Matyszewski, Krzysztof, Pluta, Elżbieta, Borek, Bartłomiej, Stefaniak, Filip, Zagozdzon, Agnieszka, Mazurkiewicz, Marcin, Koralewski, Robert, Czestkowski, Wojciech, Piotrowicz, Michał, Niedziejko, Piotr, Gruza, Mariusz M., Dzwonek, Karolina, Golebiowski, Adam, Golab, Jakub, Olczak, Jacek

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Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis von Koralewski, Robert, Dymek, Barbara, Mazur, Marzena, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Czestkowski, Wojciech, Matyszewski, Krzysztof, Andryianau, Gleb, Niedziejko, Piotr, Kowalski, Michal, Gruza, Mariusz, Borek, Bartłomiej, Jedrzejczak, Karol, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Kania, Magdalena, Rejczak, Tomasz, Piasecka, Sylwia, Mlacki, Michal, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Agnieszka, Bartlomiejczak, Aneta, Mozga, Witold, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Nowotny, Marcin, Olczak, Jacek, Golebiowski, Adam

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Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase von Andryianau, Gleb, Kowalski, Michal, Piotrowicz, Michal C., Rajkiewicz, Adam A., Dymek, Barbara, Sklepkiewicz, Piotr L., Pluta, Elzbieta, Stefaniak, Filip, Czestkowski, Wojciech, Olejniczak, Sylwia, Mazur, Marzena, Niedziejko, Piotr, Koralewski, Robert, Matyszewski, Krzysztof, Gruza, Mariusz, Zagozdzon, Agnieszka, Salamon, Magdalena, Rymaszewska, Aleksandra, Welzer, Mikolaj, Dzwonek, Karolina, Golab, Jakub, Olczak, Jacek, Bartoszewicz, Agnieszka, Golebiowski, Adam

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