Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia von Wang, Feng, Morita, Kiyomi, DiNardo, Courtney D., Furudate, Ken, Tanaka, Tomoyuki, Yan, Yuanqing, Patel, Keyur P., MacBeth, Kyle J., Wu, Bin, Liu, Guowen, Frattini, Mark, Matthews, Jairo A., Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Thompson, Erika J., Kadia, Tapan M., Garcia-Manero, Guillermo, Jabbour, Elias, Ravandi, Farhad, Bhalla, Kapil N., Konopleva, Marina, Kantarjian, Hagop M., Andrew Futreal, P., Takahashi, Koichi

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Comparison of the Transcriptomic Signatures in Pediatric and Adult CML von Youn, Minyoung, Smith, Stephanie M, Lee, Alex Gia, Chae, Hee-Don, Spiteri, Elizabeth, Erdmann, Jason, Galperin, Ilana, Jones, Lara Murphy, Donato, Michele, Abidi, Parveen, Bittencourt, Henrique, Lacayo, Norman, Dahl, Gary, Aftandilian, Catherine, Davis, Kara L, Matthews, Jairo A, Kornblau, Steven M, Huang, Min, Sumarsono, Nathan, Redell, Michele S, Fu, Cecilia H, Chen, I-Ming, Alonzo, Todd A, Eklund, Elizabeth, Gotlib, Jason, Khatri, Purvesh, Sweet-Cordero, E Alejandro, Hijiya, Nobuko, Sakamoto, Kathleen M

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“Triple” Combination of Targeting Methyltransferase, BCL-2 and PD-1 Facilitates Therapeutic Responses in Acute Myeloid Leukemia (AML) von Zeng, Zhihong, Herbrich, Shelley, Cai, Tianyu, Cavazos, Antonio, Manzella, Taylor, Ma, Helen, Kuruvilla, Vinitha Mary, Hayes, Kala, Matthews, Jairo A., DiNardo, Courtney D., Daver, Naval, Konopleva, Marina

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Ultrasensitive Next-Generation Sequencing-Based Measurable Residual Disease Assessment in Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia after Frontline Therapy: Cor... von Short, Nicholas J., Kantarjian, Hagop M., Patel, Keyur, Kornblau, Steven M., Jorgensen, Jeffrey L., Wang, Sa A, Konopleva, Marina, Jain, Nitin, Kebriaei, Partow, Yilmaz, Musa, Issa, Ghayas C., Matthews, Jairo A., Noor, Munazza, Garris, Rebecca, Ravandi, Farhad, Jabbour, Elias

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Quizartinib (Quiz) with Decitabine (DAC) and Venetoclax (VEN) Is Highly Active in Patients (pts) with FLT3-ITD Mutated Acute Myeloid Leukemia (AML) - RAS/MAPK Mutations Continue to... von Yilmaz, Musa, Muftuoglu, Muharrem, Kantarjian, Hagop, DiNardo, Courtney D., Kadia, Tapan M., Konopleva, Marina, Borthakur, Gautam, Pemmaraju, Naveen, Short, Nicholas J., Alvarado, Yesid, Maiti, Abhishek, Masarova, Lucia, Montalban-Bravo, Guillermo, Jurisprudencia, Carissa, Pike, Allison M., Loghavi, Sanam, Patel, Keyur, Tang, Guilin, Matthews, Jairo A., Kornblau, Steven M., Jabbour, Elias J., Garcia-Manero, Guillermo, Ruvolo, Vivian, Ravandi, Farhad, Andreeff, Michael, Daver, Naval

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Gene Expression Analysis of CML Patients across the Age Spectrum von Youn, Minyoung, Smith, Stephanie M., Lee, Alex Gia, Chae, Hee-Don, Spiteri, Elizabeth, Erdmann, Jason, Galperin, Ilana, Murphy, Lara C., Donato, Michele, Abidi, Parveen, Bittencourt, Henrique, Lacayo, Norman J., Dahl, Gary, Aftandilian, Catherine, Davis, Kara L., Matthews, Jairo A., Kornblau, Steven M., Huang, Min, Sumarsono, Nathan, Redell, Michele, Fu, Cecilia H., Chen, I-Ming L, Alonzo, Todd A., Eklund, Elizabeth A., Gotlib, Jason, Khatri, Purvesh, Sweet-Cordero, Alejandro, Hijiya, Nobuko, Sakamoto, Kathleen M.

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Comparison of the Transcriptomic Signatures in Pediatric and Adult CML von Youn, Minyoung, Chae, Hee-Don, Smith, Stephanie M., Lee, Alex Gia, Murphy, Lara C., Donato, Michele, Sweet-Cordero, Alejandro, Abidi, Parveen, Bittencourt, Henrique, Lacayo, Norman J., Dahl, Gary, Aftandilian, Catherine, Davis, Kara L, Matthews, Jairo A., Kornblau, Steven M., Huang, Min, Sumarsono, Nathan, Redell, Michele, Fu, Cecilia H., Chen, I-Ming L, Alonzo, Todd A., Eklund, Elizabeth A., Gotlib, Jason, Khatri, Purvesh, Hijiya, Nobuko, Sakamoto, Kathleen M.

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Azacitidine (AZA) with Nivolumab (Nivo), and AZA with Nivo + Ipilimumab (Ipi) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia: Clinical and Immune Biomarkers of Response von Daver, Naval, Basu, Sreyashi, Garcia-Manero, Guillermo, Abbas, Hussein A, Konopleva, Marina, Kadia, Tapan M., DiNardo, Courtney D., Borthakur, Gautam, Alotaibi, Ahmad S., Pemmaraju, Naveen, Jabbour, Elias, Pierce, Sherry A., Brandt, Mark, Takahashi, Koichi, Ning, Jing, Kornblau, Steven M., Sasaki, Koji, Yilmaz, Musa, Issa, Ghayas C., Short, Nicholas J., Matthews, Jairo A., Flores, Wilmer, Andreeff, Michael, Cortes, Jorge E., Ravandi, Farhad, Allison, James P, Kantarjian, Hagop M., Sharma, Padmanee

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Single-Cell Characterization of Acute Myeloid Leukemia (AML) and Its Microenvironment Identifies Signatures of Resistance to PD-1 Blockade Based Therapy von Abbas, Hussein A, Hao, Dapeng, Tomczak, Katarzyna, Barrodia, Praveen, Im, Jin S., Reville, Patrick K, Alaniz, Zoe, Wang, Wei, Wang, Ruiping, Wang, Feng, Takahashi, Koichi, Ning, Jing, Ding, Maomao, Matthews, Jairo A., Little, Latasha, Zhang, Jianhua, Basu, Sreyashi, DiNardo, Courtney D., Kadia, Tapan M., Ravandi, Farhad, Borthakur, Gautam, Konopleva, Marina, Garcia-Manero, Guillermo, Green, Michael R, Alatrash, Gheath, Sharma, Padmanee, Allison, James P, Kornblau, Steven M., Rai, Kunal, Wang, Linghua, Futreal, P Andrew, Daver, Naval

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Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma von Yang, L, Wang, H, Kornblau, S M, Graber, D A, Zhang, N, Matthews, J A, Wang, M, Weber, D M, Thomas, S K, Shah, J J, Zhang, L, Lu, G, Zhao, M, Muddasani, R, Yoo, S-Y, Baggerly, K A, Orlowski, R Z

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Activation of the Wnt/β-Catenin Pathway Mediates Lenalidomide Resistance in Multiple Myeloma von Bjorklund, Chad C., Kuhn, Deborah J., Matthews, Jairo A., Wang, Michael, Baladandayuthapani, Veerabhadran, Orlowski, Robert Z.

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Myeloma and the Microenvironment: Macrophages Are a Protector of Myeloma Cells Apoptosis Induced by Chemotherapy Drugs von Yang, Jing, Zheng, Yuhuan, Cai, Zhen, Qian, Jianfei, Hong, Sungyoul, Li, Haiyan, Matthews, Jairo A., Wang, Michael, Yi, Qing

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Bortezomib Resistance Is Mediated by Increased Signaling through the Insulin-Like Growth Factor-1/Akt Axis von Kuhn, Deborah J., Bjorklund, Chad C., Magarotto, Valeria, Matthews, Jairo A., Wang, Michael, Baladandayuthapani, Veerabhadran, Orlowski, Robert Z.

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Inhibition of Interleukin-6 Signaling with CNTO 328 Sensitizes Plasma Cell Dyscrasias to the Effects of Melphalan in Association with Suppression of Signaling through Protein Kinas... von Hunsucker, Sally A., Magarotto, Valeria, Matthews, Jairo A., Wang, Michael, Baladandayuthapani, Veerabhadran, Voorhees, Peter M., Xie, Hong, Cornfeld, Mark, Nemeth, Jeffrey A., Orlowski, Robert Z.

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Constitutive Activation of p38 MAPK in Myeloma Cells Contributes to Myeloma-Induced Osteolytic Bone Lesions von Yang, Jing, Cao, Yabing, Zheng, Yuhuan, Hong, Sungyoul, Li, Haiyan, Qian, Jianfei, Matthews, Jairo A., Wang, Michael, Kwak, Larry W., Yi, Qing

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Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics von Morita, Kiyomi, Wang, Feng, Jahn, Katharina, Hu, Tianyuan, Tanaka, Tomoyuki, Sasaki, Yuya, Kuipers, Jack, Loghavi, Sanam, Wang, Sa A., Yan, Yuanqing, Furudate, Ken, Matthews, Jairo, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Song, Xingzhi, Thompson, Erika, Patel, Keyur P., Bueso-Ramos, Carlos E., DiNardo, Courtney D., Ravandi, Farhad, Jabbour, Elias, Andreeff, Michael, Cortes, Jorge, Bhalla, Kapil, Garcia-Manero, Guillermo, Kantarjian, Hagop, Konopleva, Marina, Nakada, Daisuke, Navin, Nicholas, Beerenwinkel, Niko, Futreal, P. Andrew, Takahashi, Koichi

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A roadmap for island biology: 50 fundamental questions after 50 years of "The Theory of Island Biogeography" von Patiño, Jairo, Whittaker, Robert J., Borges, Paulo A.V., Fernández-Palacios, José María, Ah-Peng, Claudine, Araújo, Miguel B., Ávila, Sergio P., Cardoso, Pedro, Cornuault, Josselin, de Boer, Erik J., de Nascimento, Lea, Gil, Artur, González-Castro, Aarón, Gruner, Daniel S., Heleno, Ruben, Hortal, Joaquín, Illera, Juan Carlos, Kaiser-Bunbury, Christopher N., Matthews, Thomas J., Papadopoulou, Anna, Pettorelli, Nathalie, Price, Jonathan P., Santos, Ana M. C., Steinbauer, Manuel J., Triantis, Kostas A., Valente, Luis, Vargas, Pablo, Weigelt, Patrick, Emerson, Brent C.

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The effect of eltrombopag in managing thrombocytopenia associated with tyrosine kinase therapy in patients with chronic myeloid leukemia and myelofibrosis von Shoukier, Mahran, Borthakur, Gautam, Jabbour, Elias, Ravandi, Farhad, Garcia-Manero, Guillermo, Kadia, Tapan, Matthews, Jairo, Masarova, Lucia, Naqvi, Kiran, Sasaki, Koji, Verstovsek, Srdan, Cortes, Jorge

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Clonal dynamics and clinical implications of postremission clonal hematopoiesis in acute myeloid leukemia von Tanaka, Tomoyuki, Morita, Kiyomi, Loghavi, Sanam, Wang, Feng, Furudate, Ken, Sasaki, Yuya, Little, Latasha, Gumbs, Curtis, Matthews, Jairo, Daver, Naval, Pemmaraju, Naveen, DiNardo, Courtney D., Sasaki, Koji, Yilmaz, Musa, Kadia, Tapan M., Ravandi, Farhad, Konopleva, Marina Y., Kantarjian, Hagop M., Champlin, Richard E., Al-Atrash, Gheath, Garcia-Manero, Guillermo, Wang, Sa A., Futreal, P. Andrew, Takahashi, Koichi

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A Multicenter, Randomized Trial of Ramped Position vs Sniffing Position During Endotracheal Intubation of Critically Ill Adults von Semler, Matthew W., Janz, David R., Russell, Derek W., Casey, Jonathan D., Lentz, Robert J., Zouk, Aline N., deBoisblanc, Bennett P., Santanilla, Jairo I., Khan, Yasin A., Joffe, Aaron M., Stigler, William S., Rice, Todd W., Creek, Grady P., Haddock, Jody L., Vonderhaar, Derek J., Lapinel, Nicole C., Samant, Sneha D., Paccione, Rose, Dischert, Kevin, Majid-Moosa, Abdulla, Crespo, Joaquin, Fashho, Michael B., Matthews, Daniel T., Zinggeler Berg, Jeannette, Assad, Tufik R., McKown, Andrew C., Huerta, Luis E., Kocurek, Emily G., Halliday, Stephen J., Kerchberger, Vern E., Merrick, Christopher M., Warren, Melissa A., Brown, Ryan M., Self, Wesley H., Sharif, Roozbeh, Garcia, Bryan, Gulati, Swati, He, Chao, LaFon, David C.

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