Adaptive designs in clinical trials: why use them, and how to run and report them von Pallmann, Philip, Bedding, Alun W, Choodari-Oskooei, Babak, Dimairo, Munyaradzi, Flight, Laura, Hampson, Lisa V, Holmes, Jane, Mander, Adrian P, Odondi, Lang'o, Sydes, Matthew R, Villar, Sofía S, Wason, James M S, Weir, Christopher J, Wheeler, Graham M, Yap, Christina, Jaki, Thomas

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Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis von Burdett, Sarah, Boevé, Liselotte M., Ingleby, Fiona C., Fisher, David J., Rydzewska, Larysa H., Vale, Claire L., van Andel, George, Clarke, Noel W., Hulshof, Maarten C., James, Nicholas D., Parker, Christopher C., Parmar, Mahesh K., Sweeney, Christopher J., Sydes, Matthew R., Tombal, Bertrand, Verhagen, Paul C., Tierney, Jayne F.

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Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggreg... von Vale, Claire L, Dr, Burdett, Sarah, MSc, Rydzewska, Larysa H M, BSc, Albiges, Laurence, MD, Clarke, Noel W, Prof, Fisher, David, MSc, Fizazi, Karim, Prof, Gravis, Gwenaelle, MD, James, Nicholas D, Prof, Mason, Malcolm D, Prof, Parmar, Mahesh K B, Prof, Sweeney, Christopher J, MBBS, Sydes, Matthew R, CStat, Tombal, Bertrand, Prof, Tierney, Jayne F, PhD

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Practical methods for incorporating summary time-to-event data into meta-analysis von Tierney, Jayne F, Stewart, Lesley A, Ghersi, Davina, Burdett, Sarah, Sydes, Matthew R

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Abiraterone in “High-” and “Low-risk” Metastatic Hormone-sensitive Prostate Cancer von Hoyle, Alex P., Ali, Adnan, James, Nicholas D., Cook, Adrian, Parker, Christopher C., de Bono, Johann S., Attard, Gerhardt, Chowdhury, Simon, Cross, William R., Dearnaley, David P., Brawley, Christopher D., Gilson, Clare, Ingleby, Fiona, Gillessen, Silke, Aebersold, Daniel M., Jones, Rob J., Matheson, David, Millman, Robin, Mason, Malcolm D., Ritchie, Alastair W.S., Russell, Martin, Douis, Hassan, Parmar, Mahesh K.B., Sydes, Matthew R., Clarke, Noel W.

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Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partn... von Law, Martin, Couturier, Dominique-Laurent, Choodari-Oskooei, Babak, Crout, Phillip, Gamble, Carrol, Jacko, Peter, Pallmann, Philip, Pilling, Mark, Robertson, David S, Robling, Michael, Sydes, Matthew R, Villar, Sofía S, Wason, James, Wheeler, Graham, Williamson, S Faye, Yap, Christina, Jaki, Thomas

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Escalated-dose versus control-dose conformal radiotherapy for prostate cancer: long-term results from the MRC RT01 randomised controlled trial von Dearnaley, David P, Prof, Jovic, Gordana, PhD, Syndikus, Isabel, FRCR, Khoo, Vincent, FRCR, Cowan, Richard A, FRCR, Graham, John D, FRCR, Aird, Edwin G, PhD, Bottomley, David, FRCR, Huddart, Robert A, FRCR, Jose, Chakiath C, FRANZCR, Matthews, John H L, FRANZCR, Millar, Jeremy L, FRANZCR, Murphy, Claire, BSc, Russell, J Martin, FRCR, Scrase, Christopher D, FRCR, Parmar, Mahesh K B, Prof, Sydes, Matthew R, MSc

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Combined androgen deprivation therapy and radiation therapy for locally advanced prostate cancer: a randomised, phase 3 trial von Warde, Padraig, Dr, Mason, Malcolm, MB, Ding, Keyue, PhD, Kirkbride, Peter, MB, Brundage, Michael, MD, Cowan, Richard, MB, Gospodarowicz, Mary, MD, Sanders, Karen, BSc, Kostashuk, Edmund, MD, Swanson, Greg, MD, Barber, Jim, MB, Hiltz, Andrea, MSc, Parmar, Mahesh KB, PhD, Sathya, Jinka, MB, Anderson, John, MB, Hayter, Charles, MD, Hetherington, John, MB, Sydes, Matthew R, CStat, Parulekar, Wendy, MD

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Final Report of the Intergroup Randomized Study of Combined Androgen-Deprivation Therapy Plus Radiotherapy Versus Androgen-Deprivation Therapy Alone in Locally Advanced Prostate Ca... von Mason, Malcolm D, Parulekar, Wendy R, Sydes, Matthew R, Brundage, Michael, Kirkbride, Peter, Gospodarowicz, Mary, Cowan, Richard, Kostashuk, Edmund C, Anderson, John, Swanson, Gregory, Parmar, Mahesh K B, Hayter, Charles, Jovic, Gordana, Hiltz, Andrea, Hetherington, John, Sathya, Jinka, Barber, James B P, McKenzie, Michael, El-Sharkawi, Salah, Souhami, Luis, Hardman, P D John, Chen, Bingshu E, Warde, Padraig

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Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy von Kerns, Sarah L, Fachal, Laura, Dorling, Leila, Barnett, Gillian C, Baran, Andrea, Peterson, Derick R, Hollenberg, Michelle, Hao, Ke, Narzo, Antonio Di, Ahsen, Mehmet Eren, Pandey, Gaurav, Bentzen, Søren M, Janelsins, Michelle, Elliott, Rebecca M, Pharoah, Paul D P, Burnet, Neil G, Dearnaley, David P, Gulliford, Sarah L, Hall, Emma, Sydes, Matthew R, Aguado-Barrera, Miguel E, Gómez-Caamaño, Antonio, Carballo, Ana M, Peleteiro, Paula, Lobato-Busto, Ramón, Stock, Richard, Stone, Nelson N, Ostrer, Harry, Usmani, Nawaid, Singhal, Sandeep, Tsuji, Hiroshi, Imai, Takashi, Saito, Shiro, Eeles, Rosalind, DeRuyck, Kim, Parliament, Matthew, Dunning, Alison M, Vega, Ana, Rosenstein, Barry S, West, Catharine M L

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Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial von South, Annabelle, Joharatnam-Hogan, Nalinie, Purvis, Cara, James, Elizabeth C., Diaz-Montana, Carlos, Cragg, William J., Tweed, Conor, Macnair, Archie, Sydes, Matthew R., Snowdon, Claire, Gillies, Katie, Isaacs, Talia, Bierer, Barbara E., Copas, Andrew J., Davidson, Callam

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Reporting guidelines for clinical trials of artificial intelligence interventions: the SPIRIT-AI and CONSORT-AI guidelines von Ibrahim, Hussein, Liu, Xiaoxuan, Rivera, Samantha Cruz, Moher, David, Chan, An-Wen, Sydes, Matthew R., Calvert, Melanie J., Denniston, Alastair K.

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Dose–Volume Constraints to Reduce Rectal Side Effects From Prostate Radiotherapy: Evidence From MRC RT01 Trial ISRCTN 47772397 von Gulliford, Sarah L., Ph.D, Foo, Kerwyn, F.R.A.N.Z.C.R, Morgan, Rachel C., M.Sc, Aird, Edwin G., Ph.D, Bidmead, A. Margaret, M.Sc, Critchley, Helen, Ph.D, Evans, Philip M., D.Phil, Gianolini, Stefano, Ph.D, Mayles, W. Philip, Ph.D, Moore, A. Rollo, M.Sc, Sánchez-Nieto, Beatriz, Ph.D, Partridge, Mike, Ph.D, Sydes, Matthew R., C.Stat, Webb, Steve, D.Sc, Dearnaley, David P., F.R.C.R

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A new trial monitoring plan (TMP) template for clinical trials: output from a Delphi process von Taheri, Shiva, Yorke-Edwards, Victoria, Sydes, Matthew R, Isaacs, Talia, Love, Sharon B

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The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site sta... von South, Annabelle, Snowdon, Claire, Burnett, Eva, Bierer, Barbara E, Gillies, Katie, Isaacs, Talia, Sydes, Matthew R

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Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled... von Dearnaley, David P, Prof, Mason, Malcolm D, Prof, Parmar, Mahesh KB, Prof, Sanders, Karen, BSc, Sydes, Matthew R, MSc

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A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1 von Fachal, Laura, Gómez-Caamaño, Antonio, Barnett, Gillian C, Peleteiro, Paula, Carballo, Ana M, Calvo-Crespo, Patricia, Kerns, Sarah L, Sánchez-García, Manuel, Lobato-Busto, Ramón, Dorling, Leila, Elliott, Rebecca M, Dearnaley, David P, Sydes, Matthew R, Hall, Emma, Burnet, Neil G, Carracedo, Ángel, Rosenstein, Barry S, West, Catharine M L, Dunning, Alison M, Vega, Ana

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Clinical trial designs for rare diseases: Studies developed and discussed by the International Rare Cancers Initiative von Bogaerts, Jan, Sydes, Matthew R, Keat, Nicola, McConnell, Andrea, Benson, Al, Ho, Alan, Roth, Arnaud, Fortpied, Catherine, Eng, Cathy, Peckitt, Clare, Coens, Corneel, Pettaway, Curtis, Arnold, Dirk, Hall, Emma, Marshall, Ernie, Sclafani, Francesco, Hatcher, Helen, Earl, Helena, Ray-Coquard, Isabelle, Paul, James, Blay, Jean-Yves, Whelan, Jeremy, Panageas, Kathy, Wheatley, Keith, Harrington, Kevin, Licitra, Lisa, Billingham, Lucinda, Hensley, Martee, McCabe, Martin, Patel, Poulam M, Carvajal, Richard, Wilson, Richard, Glynne-Jones, Rob, McWilliams, Rob, Leyvraz, Serge, Rao, Sheela, Nicholson, Steve, Filiaci, Virginia, Negrouk, Anastassia, Lacombe, Denis, Dupont, Elisabeth, Pauporté, Iris, Welch, John J, Law, Kate, Trimble, Ted, Seymour, Matthew

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Prospective reporting of statistical analysis plans for randomised controlled trials von Hemming, Karla, Kearney, Anna, Gamble, Carrol, Li, Tianjing, Juni, Peter, Chan, An-Wen, Sydes, Matthew R.

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Monitoring in practice - How are UK academic clinical trials monitored? A survey von Love, Sharon B., Yorke-Edwards, Victoria, Lensen, Sarah, Sydes, Matthew R.

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