Cellular senescence: a key therapeutic target in aging and diseases von Zhang, Lei, Pitcher, Louise E, Yousefzadeh, Matthew J, Niedernhofer, Laura J, Robbins, Paul D, Zhu, Yi

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Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks von Wyatt, David W., Feng, Wanjuan, Conlin, Michael P., Yousefzadeh, Matthew J., Roberts, Steven A., Mieczkowski, Piotr, Wood, Richard D., Gupta, Gaorav P., Ramsden, Dale A.

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Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice von Yousefzadeh, Matthew J., Zhao, Jing, Bukata, Christina, Wade, Erin A., McGowan, Sara J., Angelini, Luise A., Bank, Michael P., Gurkar, Aditi U., McGuckian, Collin A., Calubag, Mariah F., Kato, Jonathan I., Burd, Christin E., Robbins, Paul D., Niedernhofer, Laura J.

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Mechanism of suppression of chromosomal instability by DNA polymerase POLQ von Yousefzadeh, Matthew J, Wyatt, David W, Takata, Kei-Ichi, Mu, Yunxiang, Hensley, Sean C, Tomida, Junya, Bylund, Göran O, Doublié, Sylvie, Johansson, Erik, Ramsden, Dale A, McBride, Kevin M, Wood, Richard D

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Exercise reduces circulating biomarkers of cellular senescence in humans von Englund, Davis A., Sakamoto, Ayumi E., Fritsche, Chad M., Heeren, Amanda A., Zhang, Xu, Kotajarvi, Brian R., Lecy, Denise R., Yousefzadeh, Matthew J., Schafer, Marissa J., White, Thomas A., Atkinson, Elizabeth J., LeBrasseur, Nathan K.

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DNA polymerase POLQ and cellular defense against DNA damage von Yousefzadeh, Matthew J., Wood, Richard D.

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The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical Ramifications von Gullickson, Peter, Xu, Yunwen W, Niedernhofer, Laura J, Thompson, Elizabeth L, Yousefzadeh, Matthew J

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The 3 I's of immunity and aging: immunosenescence, inflammaging, and immune resilience von Wrona, Marianna V, Ghosh, Rituparna, Coll, Kaitlyn, Chun, Connor, Yousefzadeh, Matthew J

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Cellular senescence in acute human infectious disease: a systematic review von Miller, William C, Wallace, Stephanie, Kamm, William, Reardon, Erin, Theis-Mahon, Nicole, Yousefzadeh, Matthew J, Schmidt, Elizabeth L, Niedernhofer, Laura J, Puskarich, Michael A

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An aged immune system drives senescence and ageing of solid organs von Yousefzadeh, Matthew J., Flores, Rafael R., Zhu, Yi, Schmiechen, Zoe C., Brooks, Robert W., Trussoni, Christy E., Cui, Yuxiang, Angelini, Luise, Lee, Kyoo-A, McGowan, Sara J., Burrack, Adam L., Wang, Dong, Dong, Qing, Lu, Aiping, Sano, Tokio, O’Kelly, Ryan D., McGuckian, Collin A., Kato, Jonathan I., Bank, Michael P., Wade, Erin A., Pillai, Smitha P. S., Klug, Jenna, Ladiges, Warren C., Burd, Christin E., Lewis, Sara E., LaRusso, Nicholas F., Vo, Nam V., Wang, Yinsheng, Kelley, Eric E., Huard, Johnny, Stromnes, Ingunn M., Robbins, Paul D., Niedernhofer, Laura J.

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Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance von Takata, Kei-Ichi, Reh, Shelley, Yousefzadeh, Matthew J, Zelazowski, Maciej J, Bhetawal, Sarita, Trono, David, Lowery, Megan G, Sandoval, Maria, Takata, Yoko, Lu, Yue, Lin, Kevin, Shen, Jianjun, Kusewitt, Donna F, McBride, Kevin M, Cole, Francesca, Wood, Richard D

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Senolytics reduce coronavirus-related mortality in old mice von Camell, Christina D, Yousefzadeh, Matthew J, Zhu, Yi, Prata, Larissa G P Langhi, Huggins, Matthew A, Pierson, Mark, Zhang, Lei, O'Kelly, Ryan D, Pirtskhalava, Tamar, Xun, Pengcheng, Ejima, Keisuke, Xue, Ailing, Tripathi, Utkarsh, Espindola-Netto, Jair Machado, Giorgadze, Nino, Atkinson, Elizabeth J, Inman, Christina L, Johnson, Kurt O, Cholensky, Stephanie H, Carlson, Timothy W, LeBrasseur, Nathan K, Khosla, Sundeep, O'Sullivan, M Gerard, Allison, David B, Jameson, Stephen C, Meves, Alexander, Li, Ming, Prakash, Y S, Chiarella, Sergio E, Hamilton, Sara E, Tchkonia, Tamara, Niedernhofer, Laura J, Kirkland, James L, Robbins, Paul D

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Fisetin is a senotherapeutic that extends health and lifespan von Yousefzadeh, Matthew J., Zhu, Yi, McGowan, Sara J., Angelini, Luise, Fuhrmann-Stroissnigg, Heike, Xu, Ming, Ling, Yuan Yuan, Melos, Kendra I., Pirtskhalava, Tamar, Inman, Christina L., McGuckian, Collin, Wade, Erin A., Kato, Jonathon I., Grassi, Diego, Wentworth, Mark, Burd, Christin E., Arriaga, Edgar A., Ladiges, Warren L., Tchkonia, Tamara, Kirkland, James L., Robbins, Paul D., Niedernhofer, Laura J.

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Senescence and Inflammation: Summary of a Gerontological Society of America and National Institute on Aging-Sponsored Symposium von Zhang, Xu, Tyrrell, Daniel J, Alliston, Tamara, Schilling, Birgit, Yousefzadeh, Matthew J, Schafer, Marissa J

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Ending a diagnostic odyssey: Moving from exome to genome to identify cockayne syndrome von Friedman, Jennifer, Bird, Lynne M., Haas, Richard, Robbins, Shira L., Nahas, Shareef A., Dimmock, David P., Yousefzadeh, Matthew J., Witt, Mariah A., Niedernhofer, Laura J., Chowdhury, Shimul

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Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging von Zhang, Lei, Zhao, Jing, Mu, Xiaodong, McGowan, Sara J., Angelini, Luise, O'Kelly, Ryan D., Yousefzadeh, Matthew J., Sakamoto, Ayumi, Aversa, Zaira, LeBrasseur, Nathan K., Suh, Yousin, Huard, Johnny, Kamenecka, Theodore M., Niedernhofer, Laura J., Robbins, Paul D.

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Circulating levels of monocyte chemoattractant protein‐1 as a potential measure of biological age in mice and frailty in humans von Yousefzadeh, Matthew J., Schafer, Marissa J., Noren Hooten, Nicole, Atkinson, Elizabeth J., Evans, Michele K., Baker, Darren J., Quarles, Ellen K., Robbins, Paul D., Ladiges, Warren C., LeBrasseur, Nathan K., Niedernhofer, Laura J.

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Heterochronic parabiosis: a valuable tool to investigate cellular senescence and other hallmarks of aging von Yousefzadeh, Matthew J, Robbins, Paul D, Huffman, Derek M

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ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging von Zhao, Jing, Zhang, Lei, Lu, Aiping, Han, Yingchao, Colangelo, Debora, Bukata, Christina, Scibetta, Alex, Yousefzadeh, Matthew J, Li, Xuesen, Gurkar, Aditi U, McGowan, Sara J, Angelini, Luise, O'Kelly, Ryan, Li, Hongshuai, Corbo, Lana, Sano, Tokio, Nick, Heather, Pola, Enrico, Pilla, Smitha P S, Ladiges, Warren C, Vo, Nam, Huard, Johnny, Niedernhofer, Laura J, Robbins, Paul D

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The Ercc1 -/Δ mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration von Narasimhan, Akilavalli, Min, Seok Hong, Johnson, Laura L, Roehrich, Heidi, Cho, William, Her, Tracy K, Windschitl, Caeden, O'Kelly, Ryan D, Angelini, Luise, Yousefzadeh, Matthew J, McLoon, Linda K, Hauswirth, William W, Robbins, Paul D, Skowronska-Krawczyk, Dorota, Niedernhofer, Laura J

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