Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS von Varcianna, André, Myszczynska, Monika A., Castelli, Lydia M., O'Neill, Brendan, Kim, Yeseul, Talbot, Jordan, Nyberg, Sophie, Nyamali, Immanuelle, Heath, Paul R., Stopford, Matthew J., Hautbergue, Guillaume M., Ferraiuolo, Laura

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SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits von Hautbergue, Guillaume M., Castelli, Lydia M., Ferraiuolo, Laura, Sanchez-Martinez, Alvaro, Cooper-Knock, Johnathan, Higginbottom, Adrian, Lin, Ya-Hui, Bauer, Claudia S., Dodd, Jennifer E., Myszczynska, Monika A., Alam, Sarah M., Garneret, Pierre, Chandran, Jayanth S., Karyka, Evangelia, Stopford, Matthew J., Smith, Emma F., Kirby, Janine, Meyer, Kathrin, Kaspar, Brian K., Isaacs, Adrian M., El-Khamisy, Sherif F., De Vos, Kurt J., Ning, Ke, Azzouz, Mimoun, Whitworth, Alexander J., Shaw, Pamela J.

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C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten von Stopford, Matthew J, Higginbottom, Adrian, Hautbergue, Guillaume M, Cooper-Knock, Johnathan, Mulcahy, Padraig J, De Vos, Kurt J, Renton, Alan E, Pliner, Hannah, Calvo, Andrea, Chio, Adriano, Traynor, Bryan J, Azzouz, Mimoun, Heath, Paul R, Kirby, Janine, Shaw, Pamela J

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MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis von Glajch, Kelly E, Ferraiuolo, Laura, Mueller, Kaly A, Stopford, Matthew J, Prabhkar, Varsha, Gravanis, Achille, Shaw, Pamela J, Sadri-Vakili, Ghazaleh

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Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy von Cooper-Knock, Johnathan, Higginbottom, Adrian, Stopford, Matthew J., Highley, J. Robin, Ince, Paul G., Wharton, Stephen B., Pickering-Brown, Stuart, Kirby, Janine, Hautbergue, Guillaume M., Shaw, Pamela J.

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Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis von Allen, Scott P, Hall, Benjamin, Castelli, Lydia M, Francis, Laura, Woof, Ryan, Siskos, Alexandros P, Kouloura, Eirini, Gray, Elizabeth, Thompson, Alexander G, Talbot, Kevin, Higginbottom, Adrian, Myszczynska, Monika, Allen, Chloe F, Stopford, Matthew J, Hemingway, Jordan, Bauer, Claudia S, Webster, Christopher P, De Vos, Kurt J, Turner, Martin R, Keun, Hector C, Hautbergue, Guillaume M, Ferraiuolo, Laura, Shaw, Pamela J

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Invited Review: Decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art von Walsh, Matthew J., Cooper-Knock, Johnathan, Dodd, Jennifer E., Stopford, Matthew J., Mihaylov, Simeon R., Kirby, Janine, Shaw, Pamela J., Hautbergue, Guillaume M.

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A High-throughput and Pathophysiologically Relevant Astrocyte-motor Neuron Co-culture Assay for Amyotrophic Lateral Sclerosis Therapeutic Discovery von Stopford, Matthew J, Allen, Scott P, Ferraiuolo, Laura

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Inosine reverses motor neuron toxicity observed in amyotrophic lateral sclerosis patient astrocytes with an adenosine deaminase deficiency von Allen, Scott P., Hall, Benjamin, Castelli, Lydia, Francis, Laura, Woof, Ryan, Higginbottom, Adrian, Myszczynska, Monika, Allen, Chloe F., Stopford, Matthew J., Webster, Christopher P., De Vos, Kurt, Hautbergue, Guillaume M., Ferraiuolo, Laura, Shaw, Pamela J.

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Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALSResearch in context von André Varcianna, Monika A. Myszczynska, Lydia M. Castelli, Brendan O'Neill, Yeseul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R. Heath, Matthew J. Stopford, Guillaume M. Hautbergue, Laura Ferraiuolo

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SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits von Hautbergue, Guillaume M, Castelli, Lydia M, Ferraiuolo, Laura, Sanchez-Martinez, Alvaro, Cooper-Knock, Johnathan, Higginbottom, Adrian, Lin, Ya-Hui, Bauer, Claudia S, Dodd, Jennifer E, Myszczynska, Monika A, Alam, Sarah M, Garneret, Pierre, Chandran, Jayanth S, Karyka, Evangelia, Stopford, Matthew J, Smith, Emma F, Kirby, Janine, Meyer, Kathrin, Kaspar, Brian K, Isaacs, Adrian M, El-Khamisy, Sherif F, De Vos, Kurt J, Ning, Ke, Azzouz, Mimoun, Whitworth, Alexander J, Shaw, Pamela J

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Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations von SNOWDEN, Julie S, ROLLINSON, Sara, GIBBONS, Linda, QUAN HU, DUPLESSIS, Daniel, NEARY, David, MANN, David M. A, PICKERING-BROWN, Stuart M, THOMPSON, Jennifer C, HARRIS, Jennifer M, STOPFORD, Cheryl L, RICHARDSON, Anna M. T, JONES, Matthew, GERHARD, Alex, DAVIDSON, Yvonne S, ROBINSON, Andrew

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FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma von Walker, Matthew P, Stopford, Charles M, Cederlund, Maria, Fang, Fang, Jahn, Christopher, Rabinowitz, Alex D, Goldfarb, Dennis, Graham, David M, Yan, Feng, Deal, Allison M, Fedoriw, Yuri, Richards, Kristy L, Davis, Ian J, Weidinger, Gilbert, Damania, Blossom, Major, Michael B

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Co-ordinated Airborne Studies in the Tropics (CAST) von Harris, Neil, Carpenter, Lucy J, Lee, James D, Vaughan, Geraint, Filus, Michal T, Jones, Roderick L, OuYang, Bin, Pyle, John A, Robinson, Andrew D, Andrews, Steven, Lewis, Alistair C, Minaeian, Jamie, Vaughan, Adam, Dorsey, James, Gallagher, Martin W, Le, Breton Michael, Newton, Richard, Percival, Carl, Ricketts, Hugo, Baugitte, Stephane, Nott, Graeme, Wellpott, Axel, Ashfold, Matthew, Flemming, Johannes, Butler, Robyn, Palmer, Paul, Stopford, Chris, Chemel, Charles, Kaye, Paul, Boesch, Hartmut, Humpage, Neil, Vick, Andy, MacKenzie, AR, Hyde, Richard, Angelov, Plamen, Manning, Alistair, Meneguz, Elena

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