PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells von Raab, Monika, Sanhaji, Mourad, Matthess, Yves, Hörlin, Albrecht, Lorenz, Ioana, Dötsch, Christina, Habbe, Nils, Waidmann, Oliver, Kurunci-Csacsko, Elisabeth, Firestein, Ron, Becker, Sven, Strebhardt, Klaus

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Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity von Matthess, Yves, Raab, Monika, Sanhaji, Mourad, Lavrik, Inna N., Strebhardt, Klaus

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Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome von Wegner, Martin, Diehl, Valentina, Bittl, Verena, de Bruyn, Rahel, Wiechmann, Svenja, Matthess, Yves, Hebel, Marie, Hayes, Michael Gb, Schaubeck, Simone, Benner, Christopher, Heinz, Sven, Bremm, Anja, Dikic, Ivan, Ernst, Andreas, Kaulich, Manuel

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Optimized metrics for orthogonal combinatorial CRISPR screens von Cetin, Ronay, Wegner, Martin, Luwisch, Leah, Saud, Sarada, Achmedov, Tatjana, Süsser, Sebastian, Vera-Guapi, Antonella, Müller, Konstantin, Matthess, Yves, Quandt, Eva, Schaubeck, Simone, Beisel, Chase L., Kaulich, Manuel

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Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8 von Helmke, Christina, Raab, Monika, Rödel, Franz, Matthess, Yves, Oellerich, Thomas, Mandal, Ranadip, Sanhaji, Mourad, Urlaub, Henning, Rödel, Claus, Becker, Sven, Strebhardt, Klaus

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Synthetic lethality in CCNE1 -amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics von Noack, Sabrina, Raab, Monika, Matthess, Yves, Sanhaji, Mourad, Krämer, Andrea, Győrffy, Balázs, Kaderali, Lars, El-Balat, Ahmed, Becker, Sven, Strebhardt, Klaus

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Conditional inhibition of cancer cell proliferation by tetracycline-responsive, H1 promoter-driven silencing of PLK1 von Matthess, Yves, Kappel, Sven, Spänkuch, Birgit, Zimmer, Brigitte, Kaufmann, Manfred, Strebhardt, Klaus

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Tumor inhibition by genomically integrated inducible RNAi-cassettes von Kappel, Sven, Matthess, Yves, Zimmer, Brigitte, Kaufmann, Manfred, Strebhardt, Klaus

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Correction: A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1 von Raab, Monika, Matthess, Yves, Raab, Christopher A., Gutfreund, Niklas, Dötsch, Volker, Becker, Sven, Sanhaji, Mourad, Strebhardt, Klaus

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A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1 von Raab, Monika, Matthess, Yves, Raab, Christopher A., Gutfreund, Niklas, Dötsch, Volker, Becker, Sven, Sanhaji, Mourad, Strebhardt, Klaus

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Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis von Matthess, Yves, Raab, Monika, Knecht, Rainald, Becker, Sven, Strebhardt, Klaus

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Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21WAF1/CIP1 von Kreis, Nina-Naomi, Sommer, Katharina, Sanhaji, Mourad, Krämer, Andrea, Matthess, Yves, Kaufmann, Manfred, Strebhardt, Klaus, Yuan, Juping

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pERK 1/2 inhibit Caspase-8 induced apoptosis in cancer cells by phosphorylating it in a cell cycle specific manner von Mandal, Ranadip, Raab, Monika, Matthess, Yves, Becker, Sven, Knecht, Rainald, Strebhardt, Klaus

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SKAP1 Protein PH Domain Determines RapL Membrane Localization and Rap1 Protein Complex Formation for T Cell Receptor (TCR) Activation of LFA-1 von Raab, Monika, Smith, Xin, Matthess, Yves, Strebhardt, Klaus, Rudd, Christopher E.

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Silencing of mammalian genes by tetracycline-inducible shRNA expression von Kappel, Sven, Matthess, Yves, Kaufmann, Manfred, Strebhardt, Klaus

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Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells von Raab, Monika, Kappel, Sven, Krämer, Andrea, Sanhaji, Mourad, Matthess, Yves, Kurunci-Csacsko, Elisabeth, Calzada-Wack, Julia, Rathkolb, Birgit, Rozman, Jan, Adler, Thure, Busch, Dirk H., Esposito, Irene, Fuchs, Helmut, Gailus-Durner, Valérie, Klingenspor, Martin, Wolf, Eckhard, Sänger, Nicole, Prinz, Florian, Angelis, Martin Hrabě de, Seibler, Jost, Yuan, Juping, Bergmann, Martin, Knecht, Rainald, Kreft, Bertolt, Strebhardt, Klaus

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Cancer Inhibition in Nude Mice After Systemic Application of U6 Promoter–Driven Short Hairpin RNAs Against PLK1 von Spänkuch, Birgit, Matthess, Yves, Knecht, Rainald, Zimmer, Brigitte, Kaufmann, Manfred, Strebhardt, Klaus

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Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) von Kreis, Nina-Naomi, Sommer, Katharina, Sanhaji, Mourad, Krämer, Andrea, Matthess, Yves, Kaufmann, Manfred, Strebhardt, Klaus, Yuan, Juping

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Ligand stimulation of CD95 induces activation of PIk3 followed by phosphorylation of caspase-8 von Christina Helmke Monika Raab Franz Rodel Yves Matthess Thomas Oellerich Ranadip Mandal Mourad Sanhaji Henning Urlaub Claus Rodel Sven Becker Klaus Strebhardt

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Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherap... von Rödel, Franz, Martin, Daniel, Helmke, Christina, Balermpas, Panagiotis, Fokas, Emmanouil, Wieland, Ulrike, Rave-Fränk, Margret, Kitz, Julia, Matthess, Yves, Raab, Monika, Strebhardt, Klaus, Rödel, Claus

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