Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS von Mattheisen, M, Samuels, J F, Wang, Y, Greenberg, B D, Fyer, A J, McCracken, J T, Geller, D A, Murphy, D L, Knowles, J A, Grados, M A, Riddle, M A, Rasmussen, S A, McLaughlin, N C, Nurmi, E L, Askland, K D, Qin, H-D, Cullen, B A, Piacentini, J, Pauls, D L, Bienvenu, O J, Stewart, S E, Liang, K-Y, Goes, F S, Maher, B, Pulver, A E, Shugart, Y Y, Valle, D, Lange, C, Nestadt, G

Volltext

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways von O'Dushlaine, C., Rossin, L., Lee P., H., Duncan, L., Parikshak N., N., Newhouse, S., Ripke, S., Neale B., M., Purcell S., M., Posthuma, D., Nurnberger J., I., Lee S., H., Faraone S., V., Perlis R., H., Mowry B., J., Thapar, A., Goddard M., E., Witte J., S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen O., A., Anjorin, A., Anney, R., Anttila, V., Arking D., E., Asherson, P., Azevedo M., H., Backlund, L., Badner J., A., Bailey A., J., Banaschewski, T., Barchas J., D., Barnes M., R., Barrett T., B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen S., E., Berrettini, W., Betancur, Catalina, Bettecken, T., Biederman, J., Binder E., B., Black D., W., Blackwood D., H., Bloss C., S., Boehnke, M., Boomsma D., I., Breuer, R., Bruggeman, R., Cormican, P., Buccola N., G., Buitelaar J., K., Bunney W., E., Buxbaum J., D., Byerley W., F., Byrne E., M., Caesar, S., Cahn, W., Cantor R., M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Mattheisen, M., Cloninger C., R., Collier D., A., Cook E., H., Coon, H., Cormand, B., Corvin, A., Coryell W., H., Craig D., W., Craig I., W., Crosbie, J., Cuccaro M., L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., de Geus E., J., Degenhardt, F., Djurovic, S., Donohoe G., J., Doyle A., E., Duan, J., Dudbridge, F., Duketis, E., Ebstein R., P., Edenberg H., J., Elia, J., Ennis, S., Etain, B., Fanous, F.

Volltext

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG, and PDCL3 von Herold, C, Hooli, B V, Mullin, K, Liu, T, Roehr, J T, Mattheisen, M, Parrado, A R, Bertram, L, Lange, C, Tanzi, R E

Volltext

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia von The Psychiatric Genomics Consortium, The Autism Spectrum Disorders Working Group Of, Anney, Richard J L, Ripke, Stephan, Anttila, Verneri, Grove, Jakob, Holmans, Peter, Huang, Hailiang, Klei, Lambertus, Lee, Phil H, Medland, Sarah E, Neale, Benjamin, Robinson, Elise, Weiss, Lauren A, Zwaigenbaum, Lonnie, Yu, Timothy W, Wittemeyer, Kerstin, Willsey, a Jeremy, Wijsman, Ellen M, Werge, Thomas, Wassink, Thomas H, Waltes, Regina, Walsh, Christopher A, Wallace, Simon, Vorstman, Jacob a S, Vieland, Veronica J, Vicente, Astrid M, Vanengeland, Herman, Tsang, Kathryn, Thompson, Ann P, Szatmari, Peter, Svantesson, Oscar, Steinberg, Stacy, Stefansson, Kari, Stefansson, Hreinn, State, Matthew W, Soorya, Latha, Silagadze, Teimuraz, Scherer, Stephen W, Schellenberg, Gerard D, Sandin, Sven, Sanders, Stephan J, Saemundsen, Evald, Rouleau, Guy A, Rogé, Bernadette, Roeder, Kathryn, Roberts, Wendy, Reichert, Jennifer, Reichenberg, Abraham, Rehnström, Karola, Regan, Regina, Poustka, Fritz, Poultney, Christopher S, Piven, Joseph, Pinto, Dalila, Pericak-Vance, Margaret A, Pejovic-Milovancevic, Milica, Pedersen, Marianne Giørtz, Pedersen, Carsten Bøcker, Paterson, Andrew D, Parr, Jeremy R, Pagnamenta, Alistair T, Oliveira, Guiomar, Nurnberger, John I, Nordentoft, Merete, Murtha, Michael T, Mouga, Susana, Mortensen, Preben Bo, Mors, Ole, Morrow, Eric M, Moreno-De-Luca, Daniel, Monaco, Anthony P, Minshew, Nancy, Merikangas, Alison, Mcmahon, William M, Mcgrew, Susan G, Mattheisen, Manuel, Martsenkovsky, Igor, Martin, Donna M, Mane, Shrikant M, Magnusson, Pall, Magalhaes, Tiago, Maestrini, Elena, Lowe, Jennifer K, Lord, Catherine, Levitt, Pat, Martin, Christa Lese, Ledbetter, David H, Leboyer, Marion, Lecouteur, Ann S, Ladd-Acosta, Christine, Kolevzon, Alexander, Klauck, Sabine M, Jacob, Suma, Iliadou, Bozenna, Hultman, Christina M, Hougaard, David M, Hertz-Picciotto, Irva, Hendren, Robert, Hansen, Christine Søholm, Haines, Jonathan L

Volltext

Rare autosomal copy number variations in early-onset familial Alzheimer’s disease von Hooli, B V, Kovacs-Vajna, Z M, Mullin, K, Blumenthal, M A, Mattheisen, M, Zhang, C, Lange, C, Mohapatra, G, Bertram, L, Tanzi, R E

Volltext

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci von Børglum, A D, Demontis, D, Grove, J, Pallesen, J, Hollegaard, M V, Pedersen, C B, Hedemand, A, Mattheisen, M, Uitterlinden, A, Nyegaard, M, Ørntoft, T, Wiuf, C, Didriksen, M, Nordentoft, M, Nöthen, M M, Rietschel, M, Ophoff, R A, Cichon, S, Yolken, R H, Hougaard, D M, Mortensen, P B, Mors, O

Volltext

Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling von Ceraudo, Emilie, Horioka, Mizuho, Mattheisen, Jordan M., Hitchman, Tyler D., Moore, Amanda R., Kazmi, Manija A., Chi, Ping, Chen, Yu, Sakmar, Thomas P., Huber, Thomas

Volltext

High loading of polygenic risk in cases with chronic schizophrenia von Meier, S M, Agerbo, E, Maier, R, Pedersen, C B, Lang, M, Grove, J, Hollegaard, M V, Demontis, D, Trabjerg, B B, Hjorthøj, C, Ripke, S, Degenhardt, F, Nöthen, M M, Rujescu, D, Maier, W, Werge, T, Mors, O, Hougaard, D M, Børglum, A D, Wray, N R, Rietschel, M, Nordentoft, M, Mortensen, P B, Mattheisen, M

Volltext

Common variant at 16p11.2 conferring risk of psychosis von Steinberg, S, de Jong, S, Pietiläinen, O P H, Lin, K, Papiol, S, Huttenlocher, J, Sigurdsson, E, Giegling, I, Breuer, R, Fraser, G, Walker, N, Melle, I, Djurovic, S, Tuulio-Henriksson, A, Suvisaari, J, Lönnqvist, J, Paunio, T, Olsen, L, Ingason, A, Pirinen, M, Strengman, E, Hougaard, D M, Ørntoft, T, Didriksen, M, Abramova, L, Kaleda, V, Arrojo, M, Arango, C, Etain, B, Bellivier, F, Méary, A, Schürhoff, F, Szoke, A, Ribolsi, M, Magni, V, Siracusano, A, Sperling, S, Rossner, M, Christiansen, C, Kiemeney, L A, Franke, B, Veldink, J, Curran, S, Bolton, P, Poot, M, Rehnstrom, K, Freitag, C M, Magnusson, P, Saemundsen, E, Martsenkovsky, I, Bikshaieva, I, Martsenkovska, I, Vashchenko, O, Raleva, M, Paketchieva, K, Pejovic Milovancevic, M, Naneishvili, N, Mikeladze, N, Vincent, J B, Farmer, A, Mitchell, P B, Wright, A, Schofield, P R, Fullerton, J M, Montgomery, G W, Rubino, I A, Kenis, G, Bitter, I, Terenius, L, Jönsson, E G, Bakker, S, van Os, J, Jablensky, A, Powell, J, Murray, R, Corvin, A, Gill, M, Morris, D, O'Neill, F A, Kendler, K, Riley, B, Craddock, N, O'Donovan, M C, Thorsteinsdottir, U, Ehrenreich, H, Carracedo, A, Golimbet, V, Børglum, A D, Mortensen, P B, Werge, T, Ophoff, R A, Rietschel, M, Cichon, S, Ruggeri, M, Tosato, S, Palotie, A, St Clair, D, Rujescu, D, Collier, D A, Stefansson, K

Volltext

Noncanonical Amino Acid Tools and Their Application to Membrane Protein Studies von De Faveri, Chiara, Mattheisen, Jordan M., Sakmar, Thomas P., Coin, Irene

Volltext

Expanding the range of ZNF804A variants conferring risk of psychosis von Steinberg, S, Mors, O, Børglum, A D, Gustafsson, O, Werge, T, Mortensen, P B, Andreassen, O A, Sigurdsson, E, Thorgeirsson, T E, Böttcher, Y, Olason, P, Ophoff, R A, Cichon, S, Gudjonsdottir, I H, Pietiläinen, O P H, Nyegaard, M, Tuulio-Henriksson, A, Ingason, A, Hansen, T, Athanasiu, L, Suvisaari, J, Lonnqvist, J, Paunio, T, Hartmann, A, Jürgens, G, Nordentoft, M, Hougaard, D, Norgaard-Pedersen, B, Breuer, R, Möller, H-J, Giegling, I, Glenthøj, B, Rasmussen, H B, Mattheisen, M, Bitter, I, Réthelyi, J M, Sigmundsson, T, Fossdal, R, Thorsteinsdottir, U, Ruggeri, M, Tosato, S, Strengman, E, Kiemeney, L A, Melle, I, Djurovic, S, Abramova, L, Kaleda, V, Walshe, M, Bramon, E, Vassos, E, Li, T, Fraser, G, Walker, N, Toulopoulou, T, Yoon, J, Freimer, N B, Cantor, R M, Murray, R, Kong, A, Golimbet, V, Jönsson, E G, Terenius, L, Agartz, I, Petursson, H, Nöthen, M M, Rietschel, M, Peltonen, L, Rujescu, D, Collier, D A, Stefansson, H, St Clair, D, Stefansson, K

Volltext

Role of common and rare APP DNA sequence variants in Alzheimer disease von Hooli, B V, Mohapatra, G, Mattheisen, M, Parrado, A R, Roehr, J T, Shen, Y, Gusella, J F, Moir, R, Saunders, A J, Lange, C, Tanzi, R E, Bertram, L

Volltext

Effects of BDNF Val66Met genotype and schizophrenia familial risk on a neural functional network for cognitive control in humans von Schweiger, J. I., Bilek, E., Schäfer, A., Braun, U., Moessnang, C., Harneit, A., Post, P., Otto, K., Romanczuk-Seiferth, N., Erk, S., Wackerhagen, C., Mattheisen, M., Mühleisen, T. W., Cichon, S., Nöthen, M. M., Frank, J., Witt, S. H., Rietschel, M., Heinz, A., Walter, H., Meyer-Lindenberg, A., Tost, H.

Volltext

Whole-genome association analysis of treatment response in obsessive-compulsive disorder von Qin, H, Samuels, J F, Wang, Y, Zhu, Y, Grados, M A, Riddle, M A, Greenberg, B D, Knowles, J A, Fyer, A J, McCracken, J T, Murphy, D L, Rasmussen, S A, Cullen, B A, Piacentini, J, Geller, D, Stewart, S E, Pauls, D, Bienvenu, O J, Goes, F S, Maher, B, Pulver, A E, Valle, D, Lange, C, Mattheisen, M, McLaughlin, N C, Liang, K-Y, Nurmi, E L, Askland, K D, Nestadt, G, Shugart, Y Y

Volltext

Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder von Priebe, L, Degenhardt, F A, Herms, S, Haenisch, B, Mattheisen, M, Nieratschker, V, Weingarten, M, Witt, S, Breuer, R, Paul, T, Alblas, M, Moebus, S, Lathrop, M, Leboyer, M, Schreiber, S, Grigoroiu-Serbanescu, M, Maier, W, Propping, P, Rietschel, M, Nöthen, M M, Cichon, S, Mühleisen, T W

Volltext

The Coronavirus Calendar (CoronaCal): a simplified SARS-CoV-2 test system for sampling and retrospective analysis von Kazmi, Manija A, Thaler, David S, Åberg, Karina C, Mattheisen, Jordan M, Huber, Thomas, Sakmar, Thomas P

Volltext

Genetic code expansion to enable site‐specific bioorthogonal labeling of functional G protein‐coupled receptors in live cells von Mattheisen, Jordan M., Wollowitz, Jaina S., Huber, Thomas, Sakmar, Thomas P.

Volltext

Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susc... von Li, M, Luo, X-j, Rietschel, M, Lewis, C M, Mattheisen, M, Müller-Myhsok, B, Jamain, S, Leboyer, M, Landén, M, Thompson, P M, Cichon, S, Nöthen, M M, Schulze, T G, Sullivan, P F, Bergen, S E, Donohoe, G, Morris, D W, Hargreaves, A, Gill, M, Corvin, A, Hultman, C, Toga, A W, Shi, L, Lin, Q, Shi, H, Gan, L, Meyer-Lindenberg, A, Czamara, D, Henry, C, Etain, B, Bis, J C, Ikram, M A, Fornage, M, Debette, S, Launer, L J, Seshadri, S, Erk, S, Walter, H, Heinz, A, Bellivier, F, Stein, J L, Medland, S E, Arias Vasquez, A, Hibar, D P, Franke, B, Martin, N G, Wright, M J, Su, B

Volltext

Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD von Guo, W, Samuels, J.F, Wang, Y, Cao, H, Ritter, M, Nestadt, P.S, Krasnow, J, Greenberg, B.D, Fyer, A.J, McCracken, J.T, Geller, D.A, Murphy, D.L, Knowles, J.A, Grados, M.A, Riddle, M.A, Rasmussen, S.A, McLaughlin, N.C, Nurmi, E.L, Askland, K.D, Cullen, B.A, Piacentini, J, Pauls, D.L, Bienvenu, O.J, Stewart, S.E, Goes, F.S, Maher, B, Pulver, A.E, Valle, D, Mattheisen, M, Qian, J, Nestadt, G, Shugart, Y.Y

Volltext

Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder von Lescai, F, Als, T D, Li, Q, Nyegaard, M, Andorsdottir, G, Biskopstø, M, Hedemand, A, Fiorentino, A, O'Brien, N, Jarram, A, Liang, J, Grove, J, Pallesen, J, Eickhardt, E, Mattheisen, M, Bolund, L, Demontis, D, Wang, A G, McQuillin, A, Mors, O, Wang, J, Børglum, A D

Volltext