Bridging academic science and clinical research in the search for novel targeted anti-cancer agents von Matter, Alex

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Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug von Capdeville, Renaud, Buchdunger, Elisabeth, Zimmermann, Juerg, Matter, Alex

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Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors von Zhong, Wenhe, Koay, Ann, Ngo, Anna, Li, Yan, Nah, Qianhui, Wong, Yee Hwa, Chionh, Yok Hian, Ng, Hui Qi, Koh-Stenta, Xiaoying, Poulsen, Anders, Foo, Klement, McBee, Megan, Choong, Meng Ling, El Sahili, Abbas, Kang, Congbao, Matter, Alex, Lescar, Julien, Hill, Jeffrey, Dedon, Peter

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Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3 von Huang, Chuhui, Liew, Si Si, Lin, Grace R, Poulsen, Anders, Ang, Melgious J. Y, Chia, Brian C. S, Chew, Sin Yin, Kwek, Zekui P, Wee, John L. K, Ong, Esther H, Retna, Priya, Baburajendran, Nithya, Li, Rong, Yu, Weixuan, Koh-Stenta, Xiaoying, Ngo, Anna, Manesh, Sravanthy, Fulwood, Justina, Ke, Zhiyuan, Chung, Hwa Hwa, Sepramaniam, Sugunavathi, Chew, Xin Hui, Dinie, Nurul, Lee, May Ann, Chew, Yun Shan, Low, Choon Bing, Pendharkar, Vishal, Manoharan, Vithya, Vuddagiri, Susmitha, Sangthongpitag, Kanda, Joy, Joma, Matter, Alex, Hill, Jeffrey, Keller, Thomas H, Foo, Klement

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First‐in‐Human, Healthy Volunteers Integrated Protocol of ETC‐206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug von Teneggi, Vincenzo, Novotny‐Diermayr, Veronica, Lee, Lay Hoon, Yasin, Maryam, Yeo, Pauline, Ethirajulu, Kantharaj, Gan, Sylvia Bong Hwa, Blanchard, Stephanie E., Nellore, Ranjani, Umrani, Dhananjay N., Gomeni, Roberto, Teck, Darren Lim Wan, Li, Greg, Lu, Qing Shu, Cao, Yang, Matter, Alex

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Enhanced neutralizing antibody titers and Th1 polarization from a novel Escherichia coli derived pandemic influenza vaccine von Skibinski, David A G, Hanson, Brendon J, Lin, Yufang, von Messling, Veronika, Jegerlehner, Andrea, Tee, Jason Boon Sern, Chye, De Hoe, Wong, Steven K K, Ng, Amanda A P, Lee, Hui Yin, Au, Bijin, Lee, Bernett T K, Santoso, Lucia, Poidinger, Michael, Fairhurst, Anna-Marie, Matter, Alex, Bachmann, Martin F, Saudan, Philippe, Connolly, John E

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Rescue of oxytocin response and social behaviour in a mouse model of autism von Hörnberg, Hanna, Pérez-Garci, Enrique, Schreiner, Dietmar, Hatstatt-Burklé, Laetitia, Magara, Fulvio, Baudouin, Stephane, Matter, Alex, Nacro, Kassoum, Pecho-Vrieseling, Eline, Scheiffele, Peter

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The quest for a H1N1 flu vaccine von Matter, Alex

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Tumor angiogenesis as a therapeutic target von Matter, Alex

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Drugs’ development in acute heart failure: what went wrong? von Teneggi, Vincenzo, Sivakumar, Nithy, Chen, Deborah, Matter, Alex

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Protein kinases as antibacterial targets von Schreiber, Mark, Res, Ivica, Matter, Alex

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Rescue of oxytocin response and social behavior in a rodent model of autism von Hörnberg, Hanna, Perez-Garci, Enrique, Schreiner, Dietmar, Hattstatt-Burklé, Laetitia, Magara, Fulvio, Baudouin, Stephane, Matter, Alex, Nacro, Kassoum, Pecho-Vrieseling, Eline, Scheiffele, Peter

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Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia von Yang, Haiyan, Chennamaneni, Lohitha Rao, Ho, Melvyn Wai Tuck, Ang, Shi Hua, Tan, Eldwin Sum Wai, Jeyaraj, Duraiswamy Athisayamani, Yeap, Yoon Sheng, Liu, Boping, Ong, Esther Hq, Joy, Joma Kanikadu, Wee, John Liang Kuan, Kwek, Perlyn, Retna, Priya, Dinie, Nurul, Nguyen, Thuy Thi Hanh, Tai, Shi Jing, Manoharan, Vithya, Pendharkar, Vishal, Low, Choon Bing, Chew, Yun Shan, Vuddagiri, Susmitha, Sangthongpitag, Kanda, Choong, Meng Ling, Lee, May Ann, Kannan, Srinivasaraghavan, Verma, Chandra S, Poulsen, Anders, Lim, Sharon, Chuah, Charles, Ong, Tiong Sin, Hill, Jeffrey, Matter, Alex, Nacro, Kassoum

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A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and In vitro anti‐proliferative as well as In vivo anti‐tumor activity von Meyer, Thomas, Regenass, Urs, Fabbro, Doriano, Alteri, Enrica, Röusel, Johannes, Möller, Marcel, Caravatti, Giorgio, Matter, Alex

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Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volun... von Low, Jenny G.H, Lee, Lawrence S, Ooi, Eng Eong, Ethirajulu, Kantharaj, Yeo, Pauline, Matter, Alex, Connolly, John E, Skibinski, David A.G, Saudan, Philippe, Bachmann, Martin, Hanson, Brendon J, Lu, Qingshu, Maurer-Stroh, Sebastian, Lim, Sam, Novotny-Diermayr, Veronica

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Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine von Skibinski, David A. G., Jones, Leigh Ann, Zhu, Yuan O., Xue, Lin Wu, Au, Bijin, Lee, Bernett, Naim, Ahmad Nazri Mohamed, Lee, Audrey, Kaliaperumal, Nivashini, Low, Jenny G. H., Lee, Lawrence S., Poidinger, Michael, Saudan, Philippe, Bachmann, Martin, Ooi, Eng Eong, Hanson, Brendon J., Novotny-Diermayr, Veronica, Matter, Alex, Fairhurst, Anna-Marie, Hibberd, Martin L., Connolly, John E.

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Abstract 1172: In vivo pharmacokinetic properties and antitumor efficacy of porcupine lead inhibitors in the orthotopic murine MMTV-Wnt1 breast tumor model and the human HPAF-II pa... von Pendharkar, Vishal, Chew, Yun Shan, Manoharan, Vithya, Low, Choon Bing, Ong, Hongqian Esther, Ho, Soo Yei, Wang, Wei Ling, Athisayamani, Jeyaraj Duraiswamy, Madan, Babita, Virshup, David, Keller, Thomas Hugo, Lee, May Ann, Matter, Alex, Hill, Jeffrey, Sangthongpitag, Kanda

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Healthy Volunteers' Integrated Protocol of ETC-206, an Oral MNK 1/2 Kinase Inhibitor Oncology Drug (vol 13, pg 57, 2020) von Teneggi, Vincenzo, Novotny-Diermayr, Veronica, Lee, Lay Hoon, Yasin, Maryam, Yeo, Pauline, Ethirajulu, Kantharaj, Gan, Sylvia Bong Hwa, Blanchard, Stephanie E., Nellore, Ranjani, Umrani, Dhananjay N., Gomeni, Roberto, Teck, Darren Lim Wan, Li, Greg, Lu, Qing Shu, Cao, Yang, Matter, Alex

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Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine von Skibinski, David AG, Jones, Leigh Ann, Zhu, Yuan O, Xue, Lin Wu, Au, Bijin, Lee, Bernett, Naim, Ahmad Nazri Mohamed, Lee, Audrey, Kaliaperumal, Nivashini, Low, Jenny GH, Lee, Lawrence S, Poidinger, Michael, Saudan, Philippe, Bachmann, Martin, Ooi, Eng Eong, Hanson, Brendon J, Novotny-Diermayr, Veronica, Matter, Alex, Fairhurst, Anna-Marie, Hibberd, Martin L, Connolly, John E

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Abstract B13: ETC-159 is a novel PORCN inhibitor effective for treatment of Wnt-addicted genetically defined cancers von Madan, Babita, Ke, Zhiyuan, Harmston, Nathan, Petretto, Enrico, Hill, Jeffrey, Keller, Thomas H., Lee, May Ann, Matter, Alex, Virshup, David M.

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