Targeting oncogenic Notch signaling with SERCA inhibitors von Pagliaro, Luca, Marchesini, Matteo, Roti, Giovanni

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Hematopoiesis under telomere attrition at the single-cell resolution von Thongon, Natthakan, Ma, Feiyang, Santoni, Andrea, Marchesini, Matteo, Fiorini, Elena, Rose, Ashley, Adema, Vera, Ganan-Gomez, Irene, Groarke, Emma M., Gutierrez-Rodrigues, Fernanda, Chen, Shuaitong, Lockyer, Pamela, Schneider, Sarah, Bueso-Ramos, Carlos, Montalban-Bravo, Guillermo, Class, Caleb A., Soltysiak, Kelly A., Pellegrini, Matteo, Sahin, Ergun, Bertuch, Alison A., DiNardo, Courtney D., Garcia-Manero, Guillermo, Young, Neal S., Dwyer, Karen, Colla, Simona

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Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy von Ganan-Gomez, Irene, Yang, Hui, Ma, Feiyang, Montalban-Bravo, Guillermo, Thongon, Natthakan, Marchica, Valentina, Richard-Carpentier, Guillaume, Chien, Kelly, Manyam, Ganiraju, Wang, Feng, Alfonso, Ana, Chen, Shuaitong, Class, Caleb, Kanagal-Shamanna, Rashmi, Ingram, Justin P., Ogoti, Yamini, Rose, Ashley, Loghavi, Sanam, Lockyer, Pamela, Cambo, Benedetta, Muftuoglu, Muharrem, Schneider, Sarah, Adema, Vera, McLellan, Michael, Garza, John, Marchesini, Matteo, Giuliani, Nicola, Pellegrini, Matteo, Wang, Jing, Walker, Jason, Li, Ziyi, Takahashi, Koichi, Leverson, Joel D., Bueso-Ramos, Carlos, Andreeff, Michael, Clise-Dwyer, Karen, Garcia-Manero, Guillermo, Colla, Simona

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ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma von Marchesini, Matteo, Ogoti, Yamini, Fiorini, Elena, Aktas Samur, Anil, Nezi, Luigi, D'Anca, Marianna, Storti, Paola, Samur, Mehmet Kemal, Ganan-Gomez, Irene, Fulciniti, Maria Teresa, Mistry, Nipun, Jiang, Shan, Bao, Naran, Marchica, Valentina, Neri, Antonino, Bueso-Ramos, Carlos, Wu, Chang-Jiun, Zhang, Li, Liang, Han, Peng, Xinxin, Giuliani, Nicola, Draetta, Giulio, Clise-Dwyer, Karen, Kantarjian, Hagop, Munshi, Nikhil, Orlowski, Robert, Garcia-Manero, Guillermo, DePinho, Ronald A., Colla, Simona

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Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML von Marchesini, Matteo, Gherli, Andrea, Simoncini, Elisa, Tor, Lucas Moron Dalla, Montanaro, Anna, Thongon, Natthakan, Vento, Federica, Liverani, Chiara, Cerretani, Elisa, D’Antuono, Anna, Pagliaro, Luca, Zamponi, Raffaella, Spadazzi, Chiara, Follini, Elena, Cambò, Benedetta, Giaimo, Mariateresa, Falco, Angela, Sammarelli, Gabriella, Todaro, Giannalisa, Bonomini, Sabrina, Adami, Valentina, Piazza, Silvano, Corbo, Claudia, Lorusso, Bruno, Mezzasoma, Federica, Lagrasta, Costanza Anna Maria, Martelli, Maria Paola, La Starza, Roberta, Cuneo, Antonio, Aversa, Franco, Mecucci, Cristina, Quaini, Federico, Colla, Simona, Roti, Giovanni

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Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma von Thongon, Natthakan, Ma, Feiyang, Baran, Natalia, Lockyer, Pamela, Liu, Jintan, Jackson, Christopher, Rose, Ashley, Furudate, Ken, Wildeman, Bethany, Marchesini, Matteo, Marchica, Valentina, Storti, Paola, Todaro, Giannalisa, Ganan-Gomez, Irene, Adema, Vera, Rodriguez-Sevilla, Juan Jose, Qing, Yun, Ha, Min Jin, Fonseca, Rodrigo, Stein, Caleb, Class, Caleb, Tan, Lin, Attanasio, Sergio, Garcia-Manero, Guillermo, Giuliani, Nicola, Berrios Nolasco, David, Santoni, Andrea, Cerchione, Claudio, Bueso-Ramos, Carlos, Konopleva, Marina, Lorenzi, Philip, Takahashi, Koichi, Manasanch, Elisabet, Sammarelli, Gabriella, Kanagal-Shamanna, Rashmi, Viale, Andrea, Chesi, Marta, Colla, Simona

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Author Correction: Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy von Ganan-Gomez, Irene, Yang, Hui, Ma, Feiyang, Montalban-Bravo, Guillermo, Thongon, Natthakan, Marchica, Valentina, Richard-Carpentier, Guillaume, Chien, Kelly, Manyam, Ganiraju, Wang, Feng, Alfonso, Ana, Chen, Shuaitong, Class, Caleb, Kanagal-Shamanna, Rashmi, Ingram, Justin P., Ogoti, Yamini, Rose, Ashley, Loghavi, Sanam, Lockyer, Pamela, Cambo, Benedetta, Muftuoglu, Muharrem, Schneider, Sarah, Adema, Vera, McLellan, Michael, Garza, John, Marchesini, Matteo, Giuliani, Nicola, Pellegrini, Matteo, Wang, Jing, Walker, Jason, Li, Ziyi, Takahashi, Koichi, Leverson, Joel D., Bueso-Ramos, Carlos, Andreeff, Michael, Clise-Dwyer, Karen, Garcia-Manero, Guillermo, Colla, Simona

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Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia von Montanaro, Anna, Kitara, Samuel, Cerretani, Elisa, Marchesini, Matteo, Rompietti, Chiara, Pagliaro, Luca, Gherli, Andrea, Su, Angela, Minchillo, Maria Laura, Caputi, Mariafrancesca, Fioretzaki, Rodanthi, Lorusso, Bruno, Ross, Linda, Alexe, Gabriela, Masselli, Elena, Marozzi, Marina, Rizzi, Federica Maria Angela, La Starza, Roberta, Mecucci, Cristina, Xiong, Yan, Jin, Jian, Falco, Angela, Knoechel, Birgit, Aversa, Franco, Candini, Olivia, Quaini, Federico, Sportoletti, Paolo, Stegmaier, Kimberly, Roti, Giovanni

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P451: GENE FUSIONS AND OTHER GENOMIC EVENTS UNDERLIE VENETOCLAX AND HYPOMETHYLATING AGENT RESISTANCE AND PROVIDE NEW TARGETS IN ACUTE MYELOID LEUKEMIA von Ferrari, Anna, Zacheo, Irene, Fonzi, Eugenio, Teresa Bochicchio, Maria, Capirossi, Giorgia, Nanni, Jacopo, Paganelli, Matteo, Servilli, Chiara, Ledda, Lorenzo, Ghetti, Martina, Jandoubi, Mouna, Marchesini, Matteo, Mattei, Agnese, Martinelli, Giovanni, Simonetti, Giorgia, Marconi, Giovanni

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Strategies to Overcome Resistance Mechanisms in T-Cell Acute Lymphoblastic Leukemia von Follini, Elena, Marchesini, Matteo, Roti, Giovanni

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P953: ROLE OF THE COMBINATION OF FDG PET PLUS WHOLE BODY MRI FOR STAGING NEWLY DIAGNOSED AND RELAPSED/REFRACTORY MULTIPLE MYELOMA: A PROSPECTIVE TRIAL von Cerchione, Claudio, Nappi, Davide, Marchesini, Matteo, Feliciani, Giacomo, Prochowski Iamurri, Andrea, Ronconi, Sonia, Cangini, Delia, Ceccolini, Michela, Matuozzo, Claudia, Mammoli, Fabiana, Frabetti, Federica, Paganelli, Giovanni, Matteucci, Federica, Pallotti, Caterina, Scarpi, Emanuela, Pazzi, Chiara, Barone, Domenico, Romeo, Antonino, Simonetti, Giorgia, Musuraca, Gerardo, Martinelli, Giovanni, Rossi, Alice

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P918: ROLE OF THE COMBINATION OF FDG PET PLUS WHOLE BODY MRI FOR STAGING PATIENTS IN HIGH RISK SMOLDERING MYELOMA: A PROSPECTIVE TRIAL von Cerchione, Claudio, Nappi, Davide, Marchesini, Matteo, Ronconi, Sonia, Cangini, Delia, Ceccolini, Michela, Feliciani, Giacomo, Prochowski Iamurri, Andrea, Matuozzo, Claudia, Mammoli, Fabiana, Frabetti, Federica, Paganelli, Giovanni, Matteucci, Federica, Pallotti, Caterina, Scarpi, Emanuela, Pazzi, Chiara, Barone, Domenico, Romeo, Antonino, Simonetti, Giorgia, Musuraca, Gerardo, Martinelli, Giovanni, Rossi, Alice

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Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function von Viale, Andrea, Pettazzoni, Piergiorgio, Lyssiotis, Costas A., Ying, Haoqiang, Sánchez, Nora, Marchesini, Matteo, Carugo, Alessandro, Green, Tessa, Seth, Sahil, Giuliani, Virginia, Kost-Alimova, Maria, Muller, Florian, Colla, Simona, Nezi, Luigi, Genovese, Giannicola, Deem, Angela K., Kapoor, Avnish, Yao, Wantong, Brunetto, Emanuela, Kang, Ya’an, Yuan, Min, Asara, John M., Wang, Y. Alan, Heffernan, Timothy P., Kimmelman, Alec C., Wang, Huamin, Fleming, Jason B., Cantley, Lewis C., DePinho, Ronald A., Draetta, Giulio F.

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Novel Mechanisms of Venetoclax Resistance in Acute Myeloid Leukemia Based on Genomic Rearrangements von Zacheo, Irene, Ferrari, Anna, Fonzi, Eugenio, Bochicchio, Maria Teresa, Capirossi, Giorgia, Nanni, Jacopo, Paganelli, Matteo, Servilli, Chiara, Ledda, Lorenzo, Ghetti, Martina, Jandoubi, Mouna, Marchesini, Matteo, Mattei, Agnese, Martinelli, Giovanni, Marconi, Giovanni, Simonetti, Giorgia

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Pre-Existing Myeloid Subclones May Account for a Subset of Acute Myeloid Leukemias and Myelodysplastic Neoplasms in Patients with Pre-Existing or Contemporary Lymphoid Disorders von Mattei, Agnese, Marconi, Giovanni, Ronconi, Sonia, Cangini, Delia, Ceccolini, Michela, Cerchione, Claudio, Zacheo, Irene, Giannini, Maria Benedetta, Norata, Marianna, Martinelli, Giovanni, Ferrari, Anna, Bochicchio, Maria Teresa, Ghetti, Martina, Marchesini, Matteo, Simonetti, Giorgia, Musuraca, Gerardo, Nappi, Davide

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The Atypical Protein Kinase WNK1 Controls Leukemia Progression in TAL/LMO T-Cell Acute Lymphoblastic Leukemia von Montanaro, Anna, D'Antuono, Anna, Moron Dalla Tor, Lucas, Andrei, Pietro, Cavazzini, Filippo, Cerretani, Elisa, Vento, Federica, Simoncini, Elisa, Gherli, Andrea, Zamponi, Raffaella, Lorusso, Bruno, Todaro, Giannalisa, Giaimo, Mariateresa, La Starza, Roberta, Mecucci, Cristina, Sammarelli, Gabriella, Marchesini, Matteo, Pagliaro, Luca, Roti, Giovanni

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Significant Advancements and Evolutions in Chimeric Antigen Receptor Design von Gaimari, Anna, De Lucia, Anna, Nicolini, Fabio, Mazzotti, Lucia, Maltoni, Roberta, Rughi, Giovanna, Zurlo, Matteo, Marchesini, Matteo, Juan, Manel, Parras, Daniel, Cerchione, Claudio, Martinelli, Giovanni, Bravaccini, Sara, Tettamanti, Sarah, Pasetto, Anna, Pasini, Luigi, Magnoni, Chiara, Gazzola, Luca, Borges de Souza, Patricia, Mazza, Massimiliano

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P-057 Role of the combination of FDG-PET plus whole body MRI for staging newly diagnosed and relapsed/refractory multiple myeloma: a prospective trial von Cerchione, Claudio, Nappi, Davide, Marchesini, Matteo, Ronconi, Sonia, Cangini, Delia, Ceccolini, Michela, Simonetti, Giorgia, Musuraca, Gerardo, Martinelli, Giovanni, Rossi, Alice

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POSTER: MM-638 Role of the Combination of FDG-PET plus Whole Body MRI for Staging Newly Diagnosed and Relapsed/Refractory Multiple Myeloma (MM): A Prospective Trial von Cerchione, Claudio, Nappi, Davide, Marchesini, Matteo, Cangini, Delia, Ronconi, Sonia, Ceccolini, Michela, Musuraca, Gerardo, Martinelli, Giovanni, Rossi, Alice

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MM-638 Role of the Combination of FDG-PET plus Whole Body MRI for Staging Newly Diagnosed and Relapsed/Refractory Multiple Myeloma (MM): A Prospective Trial von Cerchione, Claudio, Nappi, Davide, Marchesini, Matteo, Cangini, Delia, Ronconi, Sonia, Ceccolini, Michela, Musuraca, Gerardo, Martinelli, Giovanni, Rossi, Alice

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