Understanding Molecular Drivers of Melanin Binding To Support Rational Design of Small Molecule Ophthalmic Drugs von Jakubiak, Paulina, Reutlinger, Michael, Mattei, Patrizio, Schuler, Franz, Urtti, Arto, Alvarez-Sánchez, Rubén

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Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity von Ho, Leona T.Y., Osterwald, Anja, Ruf, Iris, Hunziker, Daniel, Mattei, Patrizio, Challa, Pratap, Vann, Robin, Ullmer, Christoph, Rao, Ponugoti Vasanth

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An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes von Sayyed, Sufyan G., Ryu, Mi, Kulkarni, Onkar P., Schmid, Holger, Lichtnekert, Julia, Grüner, Sabine, Green, Luke, Mattei, Patrizio, Hartmann, Guido, Anders, Hans-Joachim

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Pharmacological Promiscuity: Dependence on Compound Properties and Target Specificity in a Set of Recent Roche Compounds von Peters, Jens-Uwe, Schnider, Patrick, Mattei, Patrizio, Kansy, Manfred

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Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor von Hunziker, Daniel, Reinehr, Sabrina, Palmhof, Marina, Wagner, Natalie, Biniasch, Thomas, Stute, Gesa, Mattei, Patrizio, Schmitz, Petra, DiGiorgio, Patrick, Hert, Jérôme, Rudolph, Markus G, Benz, Joerg, Stihle, Martine, Gsell, Bernard, Müller, Stephan, Gasser, Rodolfo, Schonhoven, Nina, Ullmer, Christoph, Joachim, Stephanie C

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Asymmetric Synthesis of (S)-3-Amino-4-methoxy-butan-1-ol by Way of Reductive Amination von Mattei, Patrizio, Moine, Gérard, Püntener, Kurt, Schmid, Rudolf

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A new antibiotic traps lipopolysaccharide in its intermembrane transporter von Pahil, Karanbir S., Gilman, Morgan S. A., Baidin, Vadim, Clairfeuille, Thomas, Mattei, Patrizio, Bieniossek, Christoph, Dey, Fabian, Muri, Dieter, Baettig, Remo, Lobritz, Michael, Bradley, Kenneth, Kruse, Andrew C., Kahne, Daniel

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A novel antibiotic class targeting the lipopolysaccharide transporter von Zampaloni, Claudia, Mattei, Patrizio, Bleicher, Konrad, Winther, Lotte, Thäte, Claudia, Bucher, Christian, Adam, Jean-Michel, Alanine, Alexander, Amrein, Kurt E., Baidin, Vadim, Bieniossek, Christoph, Bissantz, Caterina, Boess, Franziska, Cantrill, Carina, Clairfeuille, Thomas, Dey, Fabian, Di Giorgio, Patrick, du Castel, Pauline, Dylus, David, Dzygiel, Pawel, Felici, Antonio, García-Alcalde, Fernando, Haldimann, Andreas, Leipner, Matthew, Leyn, Semen, Louvel, Séverine, Misson, Pauline, Osterman, Andrei, Pahil, Karanbir, Rigo, Sébastien, Schäublin, Adrian, Scharf, Sebastian, Schmitz, Petra, Stoll, Theodor, Trauner, Andrej, Zoffmann, Sannah, Kahne, Daniel, Young, John A. T., Lobritz, Michael A., Bradley, Kenneth A.

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Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter von Pahil, Karanbir S., Gilman, Morgan S. A., Baidin, Vadim, Clairfeuille, Thomas, Mattei, Patrizio, Bieniossek, Christoph, Dey, Fabian, Muri, Dieter, Baettig, Remo, Lobritz, Michael, Bradley, Kenneth, Kruse, Andrew C., Kahne, Daniel

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Author Correction: A new antibiotic traps lipopolysaccharide in its intermembrane transporter von Pahil, Karanbir S., Gilman, Morgan S. A., Baidin, Vadim, Clairfeuille, Thomas, Mattei, Patrizio, Bieniossek, Christoph, Dey, Fabian, Muri, Dieter, Baettig, Remo, Lobritz, Michael, Bradley, Kenneth, Kruse, Andrew C., Kahne, Daniel

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A Real-World Perspective on Molecular Design von Kuhn, Bernd, Guba, Wolfgang, Hert, Jérôme, Banner, David, Bissantz, Caterina, Ceccarelli, Simona, Haap, Wolfgang, Körner, Matthias, Kuglstatter, Andreas, Lerner, Christian, Mattei, Patrizio, Neidhart, Werner, Pinard, Emmanuel, Rudolph, Markus G, Schulz-Gasch, Tanja, Woltering, Thomas, Stahl, Martin

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Author Correction: A novel antibiotic class targeting the lipopolysaccharide transporter von Zampaloni, Claudia, Mattei, Patrizio, Bleicher, Konrad, Winther, Lotte, Thäte, Claudia, Bucher, Christian, Adam, Jean-Michel, Alanine, Alexander, Amrein, Kurt E., Baidin, Vadim, Bieniossek, Christoph, Bissantz, Caterina, Boess, Franziska, Cantrill, Carina, Clairfeuille, Thomas, Dey, Fabian, Di Giorgio, Patrick, du Castel, Pauline, Dylus, David, Dzygiel, Pawel, Felici, Antonio, García-Alcalde, Fernando, Haldimann, Andreas, Leipner, Matthew, Leyn, Semen, Louvel, Séverine, Misson, Pauline, Osterman, Andrei, Pahil, Karanbir, Rigo, Sébastien, Schäublin, Adrian, Scharf, Sebastian, Schmitz, Petra, Stoll, Theodor, Trauner, Andrej, Zoffmann, Sannah, Kahne, Daniel, Young, John A. T., Lobritz, Michael A., Bradley, Kenneth A.

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A novel antibiotic class targeting the lipopolysaccharide transporter von Zampaloni, Claudia, Mattei, Patrizio, Bleicher, Konrad, Winther, Lotte, Thäte, Claudia, Bucher, Christian, Adam, Jean-Michel, Alanine, Alexander, Amrein, Kurt E, Baidin, Vadim, Bieniossek, Christoph, Bissantz, Caterina, Boess, Franziska, Cantrill, Carina, Clairfeuille, Thomas, Dey, Fabian, Di Giorgio, Patrick, du Castel, Pauline, Dylus, David, Dzygiel, Pawel, Felici, Antonio, García-Alcalde, Fernando, Haldimann, Andreas, Leipner, Matthew, Leyn, Semen, Louvel, Séverine, Misson, Pauline, Osterman, Andrei, Pahil, Karanbir, Rigo, Sébastien, Schäublin, Adrian, Scharf, Sebastian, Schmitz, Petra, Stoll, Theodor, Trauner, Andrej, Zoffmann, Sannah, Kahne, Daniel, Young, John A. T, Lobritz, Michael A, Bradley, Kenneth A

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Discovery of carmegliptin: A potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes von Mattei, Patrizio, Boehringer, Markus, Di Giorgio, Patrick, Fischer, Holger, Hennig, Michael, Huwyler, Joerg, Koçer, Buelent, Kuhn, Bernd, Loeffler, Bernd M., MacDonald, Alexander, Narquizian, Robert, Rauber, Etienne, Sebokova, Elena, Sprecher, Urs

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ROCK: the Roche medicinal chemistry knowledge application – design, use and impact von Mayweg, Alexander, Hofer, Urs, Schnider, Patrick, Agnetti, Fausto, Galley, Guido, Mattei, Patrizio, Lucas, Matthew, Boehm, Hans-Joachim

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A Real-World Perspective on Molecular Design: Miniperspective von Kuhn, Bernd, Guba, Wolfgang, Hert, Jérôme, Banner, David, Bissantz, Caterina, Ceccarelli, Simona, Haap, Wolfgang, Körner, Matthias, Kuglstatter, Andreas, Lerner, Christian, Mattei, Patrizio, Neidhart, Werner, Pinard, Emmanuel, Rudolph, Markus G, Schulz-Gasch, Tanja, Woltering, Thomas, Stahl, Martin

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Aryl- and heteroaryl-substituted aminobenzo[ a]quinolizines as dipeptidyl peptidase IV inhibitors von Boehringer, Markus, Fischer, Holger, Hennig, Michael, Hunziker, Daniel, Huwyler, Joerg, Kuhn, Bernd, Loeffler, Bernd M., Luebbers, Thomas, Mattei, Patrizio, Narquizian, Robert, Sebokova, Elena, Sprecher, Urs, Wessel, Hans Peter

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Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists von Dehmlow, Henrietta, Alvarez Sánchez, Rubén, Bachmann, Stephan, Bissantz, Caterina, Bliss, Fritz, Conde-Knape, Karin, Graf, Martin, Martin, Rainer E., Obst Sander, Ulrike, Raab, Susanne, Richter, Hans G.F., Sewing, Sabine, Sprecher, Urs, Ullmer, Christoph, Mattei, Patrizio

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1,3-Disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitors von Lübbers, Thomas, Böhringer, Markus, Gobbi, Luca, Hennig, Michael, Hunziker, Daniel, Kuhn, Bernd, Löffler, Bernd, Mattei, Patrizio, Narquizian, Robert, Peters, Jens-Uwe, Ruff, Yves, Wessel, Hans Peter, Wyss, Pierre

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A Flavo-Thiazolio-Cyclophane as a Functional Model for Pyruvate Oxidase von Mattei, Patrizio, Diederich, François

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