NCOA4 Deficiency Impairs Systemic Iron Homeostasis von Bellelli, Roberto, Federico, Giorgia, Matte’, Alessandro, Colecchia, David, Iolascon, Achille, Chiariello, Mario, Santoro, Massimo, De Franceschi, Lucia, Carlomagno, Francesca

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Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice von Franco, Sara Santos, De Falco, Luigia, Ghaffari, Saghi, Brugnara, Carlo, Sinclair, David A, Matte', Alessandro, Iolascon, Achille, Mohandas, Narla, Bertoldi, Mariarita, An, Xiuli, Siciliano, Angela, Rimmelé, Pauline, Cappellini, Maria Domenica, Michan, Shaday, Zoratti, Elisa, Anne, Janin, De Franceschi, Lucia

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Evidence of protective effects of recombinant ADAMTS13 in humanized model for sickle cell disease von Rossato, Paolo, Federti, Enrica, Matte, Alessandro, Glantschnig, Helmut, Canneva, Fabio, Schuster, Maria, Coulibaly, Sogue, Schrenk, Gerald, Voelkel, Dirk, Dockal, Michael, Plaimauer, Barbara, Andolfo, Immacolata, Iolascon, Achille, Rottensteiner, Hanspeter, Gritsch, Herbert, Scheiflinger, Friedrich, Hoellriegl, Werner, Franceschi, Lucia De

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Hypoxia-reperfusion affects osteogenic lineage and promotes sickle cell bone disease von Carbonare, Luca Dalle, Matte', Alessandro, Valenti, Maria Teresa, Siciliano, Angela, Mori, Antonio, Schweiger, Vittorio, Zampieri, Gino, Perbellini, Luigi, De Franceschi, Lucia

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CD66b−CD64dimCD115− cells in the human bone marrow represent neutrophil-committed progenitors von Calzetti, Federica, Finotti, Giulia, Tamassia, Nicola, Bianchetto-Aguilera, Francisco, Castellucci, Monica, Canè, Stefania, Lonardi, Silvia, Cavallini, Chiara, Matte, Alessandro, Gasperini, Sara, Signoretto, Ilaria, Benedetti, Fabio, Bonifacio, Massimiliano, Vermi, William, Ugel, Stefano, Bronte, Vincenzo, Tecchio, Cristina, Scapini, Patrizia, Cassatella, Marco A.

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Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion von Park, Shin-Young, Matte, Alessandro, Jung, Yookyung, Ryu, Jina, Anand, Wilson Babu, Han, Eun-Young, Liu, Min, Carbone, Carmine, Melisi, Davide, Nagasawa, Takashi, Locascio, Joseph J., Lin, Charles P., Silberstein, Leslie E., De Franceschi, Lucia

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Duality of Nrf2 in iron-overload cardiomyopathy von Federti, Enrica, Vinchi, Francesca, Iatcenko, Iana, Ghigo, Alessandra, Matte, Alessandro, Toya, Serge Cedrick Mbiandjeu, Siciliano, Angela, Chiabrando, Deborah, Tolosano, Emanuela, Vance, Steven Zebulon, Riccardi, Veronica, Andolfo, Immacolata, Iezzi, Manuela, Lamolinara, Alessia, Iolascon, Achille, De Franceschi, Lucia

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A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis von Lupo, Francesca, Tibaldi, Elena, Matte, Alessandro, Sharma, Alok K., Brunati, Anna Maria, Alper, Seth L., Zancanaro, Carlo, Benati, Donatella, Siciliano, Angela, Bertoldi, Mariarita, Zonta, Francesca, Storch, Alexander, Walker, Ruth H., Danek, Adrian, Bader, Benedikt, Hermann, Andreas, De Franceschi, Lucia

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Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule von Lombardi, Elisabetta, Matte, Alessandro, Risitano, Antonio M, Ricklin, Daniel, Lambris, John D, De Zanet, Denise, Jokiranta, Sakari T, Martinelli, Nicola, Scambi, Cinzia, Salvagno, Gianluca, Bisoffi, Zeno, Colato, Chiara, Siciliano, Angela, Bortolami, Oscar, Mazzuccato, Mario, Zorzi, Francesco, De Marco, Luigi, De Franceschi, Lucia

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Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis von Beneduce, Elisabetta, Matte, Alessandro, De Falco, Luigia, Mbiandjeu, Serge, Chiabrando, Deborah, Tolosano, Emanuela, Federti, Enrica, Petrillo, Sara, Mohandas, Narla, Siciliano, Angela, Babu, Wilson, Menon, Vijay, Ghaffari, Saghi, Iolascon, Achille, De Franceschi, Lucia

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New Therapeutic Options for the Treatment of Sickle Cell Disease von Matte, Alessandro, Zorzi, Francesco, Mazzi, Filippo, Federti, Enrica, Olivieri, Oliviero, De Franceschi, Lucia

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Dietary ω-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease von Kalish, Brian T, Matte, Alessandro, Andolfo, Immacolata, Iolascon, Achille, Weinberg, Olga, Ghigo, Alessandra, Cimino, James, Siciliano, Angela, Hirsch, Emilio, Federti, Enrica, Puder, Mark, Brugnara, Carlo, De Franceschi, Lucia

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Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band 3 von Matte, Alessandro, Bertoldi, Mariarita, Mohandas, Narla, An, Xiuli, Bugatti, Antonella, Brunati, Anna Maria, Rusnati, Marco, Tibaldi, Elena, Siciliano, Angela, Turrini, Franco, Perrotta, Silverio, De Franceschi, Lucia

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Oxidized and poorly glycosylated band 3 is selectively phosphorylated by Syk kinase to form large membrane clusters in normal and G6PD-deficient red blood cells von Pantaleo, Antonella, Ferru, Emanuela, Giribaldi, Giuliana, Mannu, Franca, Carta, Franco, Matte, Alessandro, de Franceschi, Lucia, Turrini, Franco

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Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity von De Franceschi, Lucia, Tomelleri, Carlo, Matte, Alessandro, Brunati, Anna Maria, Bovee-Geurts, Petra H., Bertoldi, Mariarita, Lasonder, Edwin, Tibaldi, Elena, Danek, Adrian, Walker, Ruth H., Jung, Hans H., Bader, Benedikt, Siciliano, Angela, Ferru, Emanuela, Mohandas, Narla, Bosman, Giel J. C. G.M.

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P1458: MITAPIVAT AMELIORATES IN VITRO HUMAN Β THALASSEMIC ERYTHROID MATURATION INDEX AND MODULATES THE EXPRESSION OF THE CYTOPROTECTOR PEROXIREDOXIN‐2 von Matte’, Alessandro, Huot, Richard Pozzetto, Mattarei, Andrea, Ongaro, Alberto, Passarini, Alice, Siciliano, Angela, Russo, Roberta, Iolascon, Achille, Brugnara, Carlo, De Franceschi, Lucia

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Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis von Federti, Enrica, Matte, Alessandro, Riccardi, Veronica, Peikert, Kevin, Alper, Seth L, Danek, Adrian, Walker, Ruth H, Siciliano, Angela, Iatcenko, Iana, Hermann, Andreas, De Franceschi, Lucia

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Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis von Matte, Alessandro, Wilson, Anand B, Gevi, Federica, Federti, Enrica, Recchiuti, Antonio, Ferri, Giulia, Brunati, Anna Maria, Pagano, Mario Angelo, Russo, Roberta, Leboeuf, Christophe, Janin, Anne, Timperio, Anna Maria, Iolascon, Achille, Gremese, Elisa, Dang, Lenny, Mohandas, Narla, Brugnara, Carlo, De Franceschi, Lucia

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In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury von Federti, Enrica, Matte, Alessandro, Recchiuti, Antonio, Garello, Francesca, Ghigo, Alessandra, El Nemer, Wassim, Terreno, Enzo, Amoresano, Angela, Mattoscio, Domenico, Turrini, Franco, Lebouef, Christophe, Janin, Anne, Pantaleo, Antonella, Russo, Roberta, Marin, Mickael, Iatcencko, Iana, Riccardi, Veronica, Siciliano, Angela, Iolascon, Achille, Brugnara, Carlo, De Franceschi, Lucia

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Oxidation Impacts the Intracellular Signaling Machinery in Hematological Disorders von Tibaldi, Elena, Federti, Enrica, Matte, Alessandro, Iatcenko, Iana, Wilson, Anand B, Riccardi, Veronica, Pagano, Mario Angelo, De Franceschi, Lucia

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