Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity von Sirisoma, Nilantha, Kasibhatla, Shailaja, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Baichwal, Vijay, Mather, Gary G, Jessing, Kevin, Hussain, Raouf, Hoang, Khanh, Pleiman, Christopher M, Tseng, Ben, Drewe, John, Cai, Sui Xiong

Volltext

Phase I clinical trial of MPC-6827 (Azixa), a microtubule destabilizing agent, in patients with advanced cancer von Tsimberidou, Apostolia-Maria, Akerley, Wallace, Schabel, Matthias C, Hong, David S, Uehara, Cynthia, Chhabra, Anil, Warren, Terri, Mather, Gary G, Evans, Brent A, Woodland, Deane P, Swabb, Edward A, Kurzrock, Razelle

Volltext

Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: In vitro and in vivo comparison and calculation of in vivo inhibition constants von Tran, Agnès, Rey, Elisabeth, Pons, Gérard, Rousseau, Marina, d'Athis, Philippe, Olive, Georges, Mather, Gary G., Bishop, Frances E., Wurden, Colleen J., Labroo, Rita, Trager, William F., Kunze, Kent L., Thummel, Kenneth E., Vincent, Jean C., Gillardin, Jean‐Marie, Lepage, Francis, Levy, René H.

Volltext

Cytotoxicity induced by the combination of valproic acid and tumor necrosis factor-α: Implication for valproic acid-associated hepatotoxicity syndrome von Yao, Cai-ping, Mather, Gary G, Stephens, Jeffrey R, Levy, René H

Volltext

Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model von Finnell, Richard H, Bennett, Gregory D, Mather, Gary G, Wlodarczyk, Bogdan, Bajpai, Manoj, Levy, René H

Volltext

Abstract 4386: Administration of nicotinic acid reduces or prevents adverse effects of MPC-9528, a potent and selective Nampt inhibitor von Mather, Gary G., Belcher, Valerie L., Costa, Anna, DeMie, Lynn, Roman, Orvelin, Fotheringham, Lori, Bradford, Chad

Volltext

Abstract 2628: Antitumor activity of MPC-3100, a synthetic Hsp90 inhibitor, in combination with erlotinib and sorafenib von Baichwal, Vijay R., Brown, Brita, Wettstein, Daniel, Papac, Damon I., Mather, Gary G., Carlson, Robert O.

Volltext

Abstract 2617: MPC-3100, a synthetic Hsp90 inhibitor, induces biomarker changes in vitro and i n vivo von Baichwal, Vijay R., Brown, Brita, Robinson, Rosann, Cimbora, Daniel, Wettstein, Daniel, Beelen, Andrew P., Mather, Gary G., Carlson, Robert O.

Volltext

Subchronic 90 day toxicity of dichloroacetic and trichloroacetic acid in rats von Mather, Gary G., Exon, Jerry H., Koller, Loren D.

Volltext

Abstract LB-393: The cancer metabolism inhibitor MPC-9528 induces tumor regression in xenograft models with multiple dosing schedules by causing rapid and sustained reduction in tu... von Baichwal, Vijay R., Willardsen, Adam J., Lockman, Jeff W., Murphy, Brett J., Gordillo, Ruth, Fleischer, Tracey C., Bradford, Chad L., Papac, Damon I., Mather, Gary G., Carlson, Robert O.

Volltext

Pharmacokinetic interactions with felbamate : In vitro-in vivo correlation von GLUE, P, BANFIELD, C. R, PERHACH, J. L, MATHER, G. G, RACHA, J. K, LEVY, R. H

Volltext

Nefopam enantiomers: Preclinical pharmacology/toxicology and pharmacokinetic characteristics in healthy subjects after intravenous administration von Mather, Gary G., Labroo, Rita, Le Guern, Marie-Emmanuelle, Lepage, Francis, Gillardin, Jean-Marie, Levy, René H.

Volltext

Cytotoxicity induced by the combination of valproic acid and tumor necrosis factor-α von Yao, Cai-ping, Mather, Gary G, Stephens, Jeffrey R, Levy, René H

Volltext

Effects of Subchronic Exposure of Rats to 2-Methoxyethanol or 2-Butoxyethanol: Thymic Atrophy and Immunotoxicity von EXON, JERRY H., MATHER, GARY G., BUSSIERE, JEANINE L., OLSON, DAVID P., TALCOTT, PATRICIA A.

Volltext

Characterization of a Chemically Induced Tumor Model and the Effects of Natural Killer Cell Depletion by Antiasialo GM-1 von Mather, Gary G., Talcott, Patricia A., Exon, Jerry H.

Volltext

Correlation of nuclear magnetic resonance coupling constants with transition metal–ligand bond lengths in tertiary phosphine complexes von Mather, Gary G., Pidcock, Alan, Rapsey, Graham J. N.

Volltext

METHODS OF TREATING CANCER AND RELATED DISEASES von MATHER GARY G, PLEIMAN CHRISTOPHER M

Volltext bestellen

X-Ray crystal structure analysis, nuclear magnetic resonance and Mössbauer parameters of trans-tetrachlorobis(triethylphosphine)tin( IV ) von Mather, Gary G., McLaughlin, George M., Pidcock, Alan

Volltext

Proton and phosphorus-31 nuclear magnetic resonance spectra of octahedral trisdimethylphenylphosphine complexes with meridional configurations von Lynden-Bell, Ruth M., Mather, Gary G., Pidcock, Alan

Volltext

Immunotoxicity testing in the rat: An improved multiple assay model von Exon, Jerry H., Bussiere, Jeanine L., Mather, Gary G.

Volltext